Homo sapiens

38 known processes

SMC2

structural maintenance of chromosomes 2

(Aliases: CAPE,hCAP-E,SMC2L1,FLJ10093,CAP-E)

SMC2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna packaging GO:0006323 77 0.997
dna conformation change GO:0071103 113 0.996
meiotic chromosome segregation GO:0045132 4 0.986
Mouse
chromosome segregation GO:0007059 114 0.982
mitotic sister chromatid segregation GO:0000070 53 0.971
purine nucleoside monophosphate catabolic process GO:0009128 158 0.962
Yeast
kinetochore organization GO:0051383 8 0.945
Mouse
sister chromatid segregation GO:0000819 54 0.936
meiosis i GO:0007127 4 0.925
Yeast
microtubule anchoring GO:0034453 24 0.921
regulation of meiotic cell cycle GO:0051445 4 0.909
Yeast
organelle fission GO:0048285 149 0.907
ribonucleoside monophosphate catabolic process GO:0009158 158 0.899
Yeast
nucleoside monophosphate catabolic process GO:0009125 159 0.882
Yeast
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.864
Yeast
negative regulation of meiosis GO:0045835 1 0.805
Yeast
regulation of meiosis GO:0040020 3 0.794
Yeast
nuclear division GO:0000280 128 0.748
purine nucleoside triphosphate catabolic process GO:0009146 392 0.736
Yeast
blastocyst development GO:0001824 3 0.691
mitotic cell cycle GO:0000278 326 0.689
mitotic cell cycle process GO:1903047 286 0.613
nucleoside triphosphate metabolic process GO:0009141 422 0.609
Yeast
nucleoside catabolic process GO:0009164 408 0.606
Yeast
purine ribonucleoside catabolic process GO:0046130 398 0.601
Yeast
purine nucleoside catabolic process GO:0006152 398 0.594
Yeast
mitotic chromosome condensation GO:0007076 11 0.580
meiotic nuclear division GO:0007126 10 0.576
Yeast Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.561
Yeast
purine containing compound catabolic process GO:0072523 411 0.547
Yeast
oxidation reduction process GO:0055114 396 0.534
ribonucleoside triphosphate catabolic process GO:0009203 391 0.514
Yeast
chromosome condensation GO:0030261 15 0.503
nucleoside monophosphate metabolic process GO:0009123 191 0.494
Yeast
chromosome separation GO:0051304 23 0.482
ribonucleoside catabolic process GO:0042454 406 0.450
Yeast
microtubule cytoskeleton organization GO:0000226 176 0.435
Fly
negative regulation of cell cycle process GO:0010948 121 0.418
Yeast
post embryonic development GO:0009791 2 0.413
Worm
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.400
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.398
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 412 0.386
Yeast
chromatin assembly or disassembly GO:0006333 78 0.379
negative regulation of cell cycle GO:0045786 193 0.364
Yeast
nucleoside triphosphate catabolic process GO:0009143 394 0.348
Yeast
purine nucleotide catabolic process GO:0006195 405 0.318
Yeast
nucleotide catabolic process GO:0009166 408 0.312
Yeast
purine ribonucleotide catabolic process GO:0009154 404 0.300
Yeast
mitotic nuclear division GO:0007067 119 0.298
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.278
Yeast
centrosome organization GO:0051297 58 0.270
dna dependent dna replication GO:0006261 44 0.256
regulation of response to dna damage stimulus GO:2001020 94 0.245
glycosyl compound catabolic process GO:1901658 413 0.240
Yeast
spindle organization GO:0007051 53 0.227
Fly
organophosphate catabolic process GO:0046434 430 0.195
Yeast
regulation of dna metabolic process GO:0051052 153 0.195
regulation of nuclear division GO:0051783 65 0.194
Yeast
dna repair GO:0006281 198 0.191
purine ribonucleoside metabolic process GO:0046128 437 0.190
Yeast
microtubule based process GO:0007017 210 0.189
Fly
meiotic cell cycle GO:0051321 13 0.185
Yeast Mouse
single organism reproductive process GO:0044702 98 0.184
ribonucleotide catabolic process GO:0009261 405 0.179
Yeast
gonad development GO:0008406 34 0.177
chordate embryonic development GO:0043009 34 0.173
sex differentiation GO:0007548 45 0.172
digestive tract development GO:0048565 75 0.154
mitotic sister chromatid separation GO:0051306 18 0.147
embryo development GO:0009790 123 0.134
Worm
cell division GO:0051301 168 0.132
Yeast
dna replication GO:0006260 116 0.131
female gamete generation GO:0007292 2 0.122
reproduction GO:0000003 63 0.114
Yeast Mouse
cell development GO:0048468 328 0.111
nervous system development GO:0007399 293 0.109
Fly
reproductive system development GO:0061458 56 0.109
ribonucleoside monophosphate metabolic process GO:0009161 187 0.108
Yeast
regeneration GO:0031099 4 0.106
atp catabolic process GO:0006200 157 0.105
Yeast
development of primary sexual characteristics GO:0045137 35 0.103
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.100
negative regulation of meiotic cell cycle GO:0051447 2 0.100
Yeast
developmental process involved in reproduction GO:0003006 66 0.100
regulation of dna repair GO:0006282 47 0.099
generation of precursor metabolites and energy GO:0006091 68 0.098
cellular macromolecule catabolic process GO:0044265 380 0.098
positive regulation of hydrolase activity GO:0051345 331 0.095
positive regulation of catabolic process GO:0009896 310 0.090
atp metabolic process GO:0046034 176 0.088
Yeast
regulation of nucleotide metabolic process GO:0006140 269 0.087
regulation of nucleoside metabolic process GO:0009118 209 0.084
regulation of cell cycle GO:0051726 393 0.081
Yeast
spindle assembly involved in mitosis GO:0090307 12 0.081
maintenance of location GO:0051235 112 0.080
cellular response to ionizing radiation GO:0071479 32 0.078
positive regulation of nucleotide catabolic process GO:0030813 185 0.075
double strand break repair GO:0006302 101 0.074
reproductive process GO:0022414 106 0.074
positive regulation of cellular component organization GO:0051130 376 0.073
oogenesis GO:0048477 2 0.071
negative regulation of cell division GO:0051782 31 0.070
Yeast
regulation of gene expression epigenetic GO:0040029 73 0.068
Worm
single organism cellular localization GO:1902580 332 0.067
Yeast
cellular response to dna damage stimulus GO:0006974 379 0.067
regulation of atp metabolic process GO:1903578 29 0.067
purine nucleoside monophosphate metabolic process GO:0009126 186 0.062
Yeast
reproductive structure development GO:0048608 55 0.059
tube development GO:0035295 125 0.058
response to radiation GO:0009314 151 0.056
intrinsic apoptotic signaling pathway GO:0097193 127 0.055
regulation of purine nucleotide catabolic process GO:0033121 205 0.053
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.052
Yeast
behavior GO:0007610 112 0.051
meiotic chromosome separation GO:0051307 3 0.049
cell projection organization GO:0030030 252 0.046
regulation of cell division GO:0051302 116 0.043
Yeast
regulation of purine nucleotide metabolic process GO:1900542 264 0.041
protein oligomerization GO:0051259 173 0.040
maintenance of location in cell GO:0051651 62 0.039
dna recombination GO:0006310 77 0.038
cellular macromolecular complex assembly GO:0034622 324 0.036
ribosome assembly GO:0042255 9 0.036
neuron differentiation GO:0030182 138 0.034
protein alkylation GO:0008213 74 0.033
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.032
protein depolymerization GO:0051261 30 0.032
regulation of mitotic cell cycle GO:0007346 189 0.030
histone methylation GO:0016571 60 0.030
regulation of ras protein signal transduction GO:0046578 155 0.030
dna duplex unwinding GO:0032508 30 0.030
neurogenesis GO:0022008 169 0.028
Fly
generation of neurons GO:0048699 152 0.027
sulfate transport GO:0008272 5 0.026
organelle assembly GO:0070925 176 0.025
embryo development ending in birth or egg hatching GO:0009792 34 0.025
Worm
cell part morphogenesis GO:0032990 137 0.025
negative regulation of apoptotic process GO:0043066 316 0.025
digestive tract morphogenesis GO:0048546 56 0.025
meiotic cell cycle process GO:1903046 8 0.025
Yeast Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.025
response to ionizing radiation GO:0010212 65 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.024
negative regulation of cell differentiation GO:0045596 171 0.023
negative regulation of organelle organization GO:0010639 126 0.023
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
Yeast
sister chromatid cohesion GO:0007062 24 0.022
attachment of spindle microtubules to kinetochore GO:0008608 17 0.022
cellular ketone metabolic process GO:0042180 80 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
covalent chromatin modification GO:0016569 254 0.022
maintenance of protein location in cell GO:0032507 56 0.022
regulation of double strand break repair GO:2000779 22 0.022
neuron development GO:0048666 113 0.021
mitotic spindle organization GO:0007052 27 0.020
Fly
reciprocal meiotic recombination GO:0007131 4 0.020
regulation of mitotic sister chromatid segregation GO:0033047 27 0.020
positive regulation of apoptotic process GO:0043065 246 0.020
positive regulation of organelle organization GO:0010638 195 0.020
protein targeting GO:0006605 187 0.020
chromatin organization GO:0006325 351 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
double strand break repair via homologous recombination GO:0000724 50 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
dna strand elongation involved in dna replication GO:0006271 3 0.019
tissue morphogenesis GO:0048729 96 0.019
epithelium development GO:0060429 227 0.018
protein import GO:0017038 130 0.018
regulation of cytoskeleton organization GO:0051493 177 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.018
response to inorganic substance GO:0010035 127 0.017
anatomical structure homeostasis GO:0060249 100 0.017
response to abiotic stimulus GO:0009628 336 0.017
sex determination GO:0007530 3 0.017
negative regulation of dna metabolic process GO:0051053 57 0.017
developmental growth GO:0048589 48 0.016
dosage compensation GO:0007549 3 0.016
Worm
single organism membrane organization GO:0044802 268 0.016
positive regulation of protein transport GO:0051222 135 0.016
positive regulation of atp metabolic process GO:1903580 20 0.016
negative regulation of cell death GO:0060548 345 0.016
response to caffeine GO:0031000 3 0.016
tissue regeneration GO:0042246 3 0.015
positive regulation of dna replication GO:0045740 35 0.015
cellular response to radiation GO:0071478 65 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
positive regulation of cell development GO:0010720 92 0.015
regulation of cell cycle process GO:0010564 266 0.015
Yeast
response to hormone GO:0009725 175 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
Yeast
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
receptor mediated endocytosis GO:0006898 84 0.014
regulation of proteasomal protein catabolic process GO:0061136 87 0.014
positive regulation of histone h4 k16 acetylation GO:2000620 1 0.014
wnt signaling pathway GO:0016055 156 0.014
cellular amine metabolic process GO:0044106 41 0.013
dna unwinding involved in dna replication GO:0006268 2 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
hemopoiesis GO:0030097 180 0.013
chromatin assembly GO:0031497 61 0.013
regulation of dna recombination GO:0000018 23 0.012
dendrite development GO:0016358 24 0.012
cell morphogenesis GO:0000902 296 0.012
chromatin modification GO:0016568 298 0.012
recombinational repair GO:0000725 50 0.012
multicellular organismal reproductive process GO:0048609 40 0.012
maintenance of dna repeat elements GO:0043570 4 0.012
multicellular organism reproduction GO:0032504 42 0.012
positive regulation of transport GO:0051050 336 0.012
spindle elongation GO:0051231 4 0.012
regulation of cellular response to stress GO:0080135 244 0.011
regulation of transferase activity GO:0051338 355 0.011
spermatid development GO:0007286 4 0.011
organelle localization GO:0051640 84 0.011
intracellular protein transport GO:0006886 270 0.011
mitotic cell cycle checkpoint GO:0007093 68 0.011
regulation of protein catabolic process GO:0042176 155 0.011
neuron projection development GO:0031175 106 0.011
positive regulation of mitochondrial membrane potential GO:0010918 1 0.011
negative regulation of gene expression epigenetic GO:0045814 19 0.011
genitalia development GO:0048806 10 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
positive regulation of intracellular transport GO:0032388 104 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
circulatory system development GO:0072359 262 0.010
multi organism reproductive process GO:0044703 54 0.010

SMC2 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.047
disease of cellular proliferation DOID:14566 174 0.019