Homo sapiens

112 known processes

LTK

leukocyte receptor tyrosine kinase

(Aliases: TYK1)

LTK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 41 0.503
cellular ketone metabolic process GO:0042180 80 0.457
regulation of locomotion GO:0040012 329 0.447
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.385
cellular amino acid metabolic process GO:0006520 116 0.355
regulation of cellular ketone metabolic process GO:0010565 50 0.348
regulation of cellular amine metabolic process GO:0033238 11 0.340
amine metabolic process GO:0009308 44 0.271
regulation of cellular amino acid metabolic process GO:0006521 6 0.261
positive regulation of cellular amine metabolic process GO:0033240 7 0.250
cell cell signaling GO:0007267 155 0.242
Fly
mapk cascade GO:0000165 288 0.239
Human Fly
response to oxygen containing compound GO:1901700 369 0.229
positive regulation of developmental process GO:0051094 314 0.203
anatomical structure formation involved in morphogenesis GO:0048646 284 0.202
positive regulation of cell proliferation GO:0008284 301 0.202
Human
negative regulation of programmed cell death GO:0043069 321 0.202
regulation of mapk cascade GO:0043408 262 0.199
Human Fly
system process GO:0003008 349 0.186
Fly
signal transduction by phosphorylation GO:0023014 297 0.184
Human Fly
negative regulation of multicellular organismal process GO:0051241 317 0.183
regulation of cell motility GO:2000145 299 0.165
Human
response to lipid GO:0033993 206 0.163
regulation of cellular component biogenesis GO:0044087 281 0.163
regulation of secretion by cell GO:1903530 177 0.157
cellular response to endogenous stimulus GO:0071495 336 0.155
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.155
Human
positive regulation of phosphorylation GO:0042327 394 0.152
Human Fly
post embryonic development GO:0009791 2 0.152
Worm
positive regulation of locomotion GO:0040017 186 0.143
Human
secretion GO:0046903 254 0.141
regulation of cellular component movement GO:0051270 334 0.141
Human
epithelium development GO:0060429 227 0.139
negative regulation of developmental process GO:0051093 247 0.135
neuron fate commitment GO:0048663 2 0.134
hematopoietic or lymphoid organ development GO:0048534 186 0.133
response to growth factor GO:0070848 205 0.131
cardiovascular system development GO:0072358 262 0.129
Human
regulation of kinase activity GO:0043549 314 0.129
Human Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.126
Human
ras protein signal transduction GO:0007265 73 0.123
negative regulation of cell death GO:0060548 345 0.121
regulation of cell differentiation GO:0045595 393 0.120
regulation of hormone levels GO:0010817 125 0.118
positive regulation of mapk cascade GO:0043410 190 0.118
Human Fly
sex determination GO:0007530 3 0.117
regulation of anatomical structure morphogenesis GO:0022603 286 0.115
response to hormone GO:0009725 175 0.114
Human
positive regulation of protein phosphorylation GO:0001934 313 0.112
Human Fly
immune system development GO:0002520 195 0.109
locomotory behavior GO:0007626 1 0.109
g protein coupled receptor signaling pathway GO:0007186 207 0.108
Human
amide transport GO:0042886 76 0.107
anion transport GO:0006820 161 0.107
positive regulation of cellular component organization GO:0051130 376 0.107
positive regulation of transport GO:0051050 336 0.107
Human
organophosphate catabolic process GO:0046434 430 0.106
secretion by cell GO:0032940 226 0.105
small gtpase mediated signal transduction GO:0007264 78 0.104
peptidyl tyrosine phosphorylation GO:0018108 170 0.103
Human Fly
negative regulation of cell proliferation GO:0008285 228 0.103
response to biotic stimulus GO:0009607 276 0.103
stem cell division GO:0017145 2 0.101
ameboidal type cell migration GO:0001667 135 0.095
metal ion homeostasis GO:0055065 169 0.095
response to external biotic stimulus GO:0043207 261 0.095
response to cytokine GO:0034097 232 0.093
response to other organism GO:0051707 261 0.093
actin filament based process GO:0030029 224 0.092
Human
cell activation GO:0001775 213 0.091
circulatory system development GO:0072359 262 0.090
Human
response to organic cyclic compound GO:0014070 204 0.089
regulation of cell cycle GO:0051726 393 0.089
Human
cellular calcium ion homeostasis GO:0006874 117 0.088
cytosolic calcium ion homeostasis GO:0051480 89 0.088
immune response GO:0006955 307 0.088
Human
regulation of transferase activity GO:0051338 355 0.087
Human Fly
cellular metal ion homeostasis GO:0006875 146 0.087
regulation of response to external stimulus GO:0032101 222 0.087
hemopoiesis GO:0030097 180 0.086
cellular response to hormone stimulus GO:0032870 125 0.086
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.086
endothelial cell migration GO:0043542 86 0.086
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.085
negative regulation of locomotion GO:0040013 118 0.083
regulation of secretion GO:0051046 194 0.083
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.082
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 1 0.081
ion homeostasis GO:0050801 230 0.081
cellular response to oxygen containing compound GO:1901701 276 0.081
positive regulation of transferase activity GO:0051347 227 0.081
Human Fly
negative regulation of cell differentiation GO:0045596 171 0.080
segmentation GO:0035282 4 0.078
cellular divalent inorganic cation homeostasis GO:0072503 128 0.078
epithelial cell differentiation GO:0030855 141 0.078
negative regulation of apoptotic process GO:0043066 316 0.077
regulation of cell migration GO:0030334 289 0.077
Human
cellular response to cytokine stimulus GO:0071345 181 0.075
positive regulation of catabolic process GO:0009896 310 0.075
Human
positive regulation of immune system process GO:0002684 283 0.074
lipid metabolic process GO:0006629 381 0.074
regulation of protein localization GO:0032880 296 0.074
positive regulation of cell differentiation GO:0045597 211 0.073
peptidyl tyrosine modification GO:0018212 170 0.073
Human Fly
positive regulation of kinase activity GO:0033674 204 0.072
Human Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.070
nucleoside phosphate catabolic process GO:1901292 412 0.070
positive regulation of protein kinase activity GO:0045860 190 0.070
Human Fly
cellular response to nitrogen compound GO:1901699 144 0.070
Human
regulation of protein kinase activity GO:0045859 289 0.067
Human Fly
regulation of cellular response to stress GO:0080135 244 0.066
Human
cell division GO:0051301 168 0.066
Human
positive regulation of cell death GO:0010942 263 0.066
response to abiotic stimulus GO:0009628 336 0.065
Human
positive regulation of cellular catabolic process GO:0031331 284 0.065
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.065
positive regulation of secretion by cell GO:1903532 108 0.064
regulation of thyroid hormone generation GO:2000609 2 0.064
cellular response to organonitrogen compound GO:0071417 124 0.064
Human
protein autophosphorylation GO:0046777 123 0.064
Human
cation homeostasis GO:0055080 189 0.064
somatic stem cell maintenance GO:0035019 4 0.064
biological adhesion GO:0022610 331 0.064
positive regulation of hydrolase activity GO:0051345 331 0.064
ion transmembrane transport GO:0034220 338 0.063
activation of protein kinase activity GO:0032147 90 0.062
Human Fly
pulmonary vein morphogenesis GO:0060577 1 0.062
blood vessel morphogenesis GO:0048514 162 0.062
purine nucleotide catabolic process GO:0006195 405 0.061
regulation of epithelial cell migration GO:0010632 93 0.061
cell morphogenesis GO:0000902 296 0.061
Fly
protein localization to organelle GO:0033365 280 0.059
oogenesis GO:0048477 2 0.058
inner ear morphogenesis GO:0042472 4 0.058
cation transport GO:0006812 331 0.058
regulation of purine nucleotide metabolic process GO:1900542 264 0.057
mitotic cell cycle process GO:1903047 286 0.057
Human
nucleotide catabolic process GO:0009166 408 0.057
cell morphogenesis involved in differentiation GO:0000904 144 0.056
Fly
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.056
cellular homeostasis GO:0019725 196 0.055
cellular lipid metabolic process GO:0044255 303 0.055
cranial nerve development GO:0021545 4 0.055
reactive oxygen species metabolic process GO:0072593 75 0.054
cellular ion homeostasis GO:0006873 168 0.054
cytoplasmic transport GO:0016482 379 0.054
regulation of epithelial cell proliferation GO:0050678 113 0.054
regulation of small gtpase mediated signal transduction GO:0051056 156 0.054
positive regulation of map kinase activity GO:0043406 80 0.053
Human Fly
positive regulation of cytokine production GO:0001819 167 0.053
single organism cellular localization GO:1902580 332 0.053
chemical homeostasis GO:0048878 306 0.053
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.053
Human
regulation of establishment of protein localization GO:0070201 242 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.053
tube development GO:0035295 125 0.053
Fly
cellular response to organic cyclic compound GO:0071407 127 0.053
regulation of nucleotide metabolic process GO:0006140 269 0.053
calcium ion homeostasis GO:0055074 122 0.053
positive regulation of nucleoside metabolic process GO:0045979 186 0.052
female gamete generation GO:0007292 2 0.052
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.051
Fly
myeloid cell differentiation GO:0030099 117 0.051
response to nitrogen compound GO:1901698 184 0.051
Human
neuroblast proliferation GO:0007405 4 0.050
regulation of cell cycle process GO:0010564 266 0.050
Human
muscle structure development GO:0061061 98 0.050
Fly
ribonucleotide catabolic process GO:0009261 405 0.050
blood vessel development GO:0001568 172 0.050
peptide transport GO:0015833 74 0.050
negative regulation of protein metabolic process GO:0051248 391 0.050
Human
nervous system development GO:0007399 293 0.050
cellular response to growth factor stimulus GO:0071363 197 0.049
hindbrain development GO:0030902 3 0.049
defense response to other organism GO:0098542 129 0.049
regulation of protein transport GO:0051223 213 0.049
regulation of ion transport GO:0043269 189 0.049
regulation of protein serine threonine kinase activity GO:0071900 179 0.049
Human Fly
asymmetric stem cell division GO:0098722 1 0.049
apoptotic signaling pathway GO:0097190 268 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.048
divalent inorganic cation homeostasis GO:0072507 136 0.048
embryonic forelimb morphogenesis GO:0035115 4 0.048
regulation of erk1 and erk2 cascade GO:0070372 99 0.048
Fly
fatty acid metabolic process GO:0006631 115 0.048
rhythmic behavior GO:0007622 2 0.048
blastoderm segmentation GO:0007350 2 0.048
forelimb morphogenesis GO:0035136 4 0.047
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.047
sulfur compound metabolic process GO:0006790 101 0.047
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.047
organophosphate biosynthetic process GO:0090407 163 0.047
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.047
Human Fly
mitotic cell cycle GO:0000278 326 0.047
Human
memory GO:0007613 3 0.046
cellular component morphogenesis GO:0032989 314 0.046
Fly
response to organonitrogen compound GO:0010243 156 0.046
Human
epithelial cell migration GO:0010631 119 0.046
circadian behavior GO:0048512 2 0.046
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.046
nitrogen compound transport GO:0071705 191 0.046
response to activity GO:0014823 0 0.046
reactive nitrogen species metabolic process GO:2001057 3 0.045
determination of adult lifespan GO:0008340 2 0.045
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
Human
regulation of reactive oxygen species metabolic process GO:2000377 41 0.045
positive regulation of organelle organization GO:0010638 195 0.044
Human
regulation of angiogenesis GO:0045765 92 0.044
nucleocytoplasmic transport GO:0006913 176 0.044
taxis GO:0042330 157 0.044
Fly
ribonucleoside catabolic process GO:0042454 406 0.044
organ formation GO:0048645 3 0.044
ribonucleoside triphosphate metabolic process GO:0009199 412 0.043
peripheral nervous system development GO:0007422 2 0.043
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
cardiac right ventricle morphogenesis GO:0003215 3 0.043
signal release GO:0023061 70 0.042
rho protein signal transduction GO:0007266 26 0.042
epithelium migration GO:0090132 119 0.042
defense response GO:0006952 315 0.042
cellular response to lipid GO:0071396 127 0.042
purine nucleoside catabolic process GO:0006152 398 0.042
guanosine containing compound catabolic process GO:1901069 239 0.042
cell type specific apoptotic process GO:0097285 125 0.042
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.041
regulation of response to wounding GO:1903034 101 0.041
activation of mapk activity GO:0000187 45 0.041
Human Fly
nerve development GO:0021675 4 0.041
reproductive process GO:0022414 106 0.041
regulation of cell development GO:0060284 161 0.041
behavior GO:0007610 112 0.041
Fly
cell adhesion GO:0007155 325 0.040
positive regulation of cell cycle process GO:0090068 106 0.040
Human
cellular modified amino acid metabolic process GO:0006575 64 0.040
multicellular organismal aging GO:0010259 3 0.040
purine nucleoside triphosphate catabolic process GO:0009146 392 0.040
purine ribonucleoside metabolic process GO:0046128 437 0.039
monocarboxylic acid metabolic process GO:0032787 185 0.039
Human
multi organism cellular process GO:0044764 156 0.039
Human
negative regulation of protein modification process GO:0031400 200 0.039
Human
cation transmembrane transport GO:0098655 238 0.039
immune effector process GO:0002252 159 0.039
guanosine containing compound metabolic process GO:1901068 244 0.039
leukocyte differentiation GO:0002521 98 0.039
cell fate determination GO:0001709 3 0.039
glycosyl compound catabolic process GO:1901658 413 0.039
cytokine production GO:0001816 247 0.039
negative regulation of cellular component organization GO:0051129 235 0.038
lymphocyte activation GO:0046649 133 0.038
regulation of growth GO:0040008 165 0.038
Human Fly
aortic valve development GO:0003176 3 0.038
regulation of homeostatic process GO:0032844 121 0.038
organonitrogen compound biosynthetic process GO:1901566 200 0.037
outflow tract septum morphogenesis GO:0003148 4 0.037
reactive oxygen species biosynthetic process GO:1903409 4 0.037
photoreceptor cell differentiation GO:0046530 2 0.037
Fly
cell growth GO:0016049 160 0.037
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.036
regulation of purine nucleotide catabolic process GO:0033121 205 0.036
regulation of chemotaxis GO:0050920 74 0.036
cellular response to dna damage stimulus GO:0006974 379 0.036
negative regulation of gliogenesis GO:0014014 3 0.036
foramen ovale closure GO:0035922 1 0.036
negative regulation of protein phosphorylation GO:0001933 140 0.036
Human
positive regulation of cell division GO:0051781 59 0.036
Human
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
Human
cellular chemical homeostasis GO:0055082 180 0.035
chromatin organization GO:0006325 351 0.035
hormone secretion GO:0046879 65 0.035
second messenger mediated signaling GO:0019932 78 0.035
regeneration GO:0031099 4 0.035
astrocyte differentiation GO:0048708 4 0.035
positive regulation of cell migration GO:0030335 172 0.035
Human
response to virus GO:0009615 126 0.034
regulation of cell morphogenesis GO:0022604 153 0.034
regulation of anatomical structure size GO:0090066 101 0.034
Fly
vesicle mediated transport GO:0016192 371 0.034
positive regulation of apoptotic process GO:0043065 246 0.034
hormone transport GO:0009914 68 0.034
response to bacterium GO:0009617 144 0.034
organic anion transport GO:0015711 103 0.034
spinal cord development GO:0021510 4 0.033
gtp metabolic process GO:0046039 239 0.033
central nervous system development GO:0007417 123 0.033
embryonic morphogenesis GO:0048598 85 0.033
regulation of ras gtpase activity GO:0032318 128 0.033
protein processing GO:0016485 226 0.033
regulation of immune response GO:0050776 201 0.033
peptidyl serine phosphorylation GO:0018105 101 0.033
metencephalon development GO:0022037 2 0.033
positive regulation of cell cycle GO:0045787 140 0.033
Human
phosphatidylinositol mediated signaling GO:0048015 55 0.032
positive regulation of cortisol biosynthetic process GO:2000066 1 0.032
nucleoside triphosphate catabolic process GO:0009143 394 0.032
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.032
cellular cation homeostasis GO:0030003 163 0.032
transmembrane transport GO:0055085 399 0.032
nuclear transport GO:0051169 179 0.031
regulation of cytokine production GO:0001817 232 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.031
positive regulation of cardioblast differentiation GO:0051891 2 0.031
purine ribonucleotide catabolic process GO:0009154 404 0.031
carbohydrate derivative biosynthetic process GO:1901137 207 0.031
regulation of cytoplasmic transport GO:1903649 149 0.031
heart morphogenesis GO:0003007 48 0.031
Human
response to axon injury GO:0048678 1 0.031
inorganic ion transmembrane transport GO:0098660 231 0.031
neuromuscular junction development GO:0007528 3 0.031
viral process GO:0016032 146 0.031
Human
regulation of gtpase activity GO:0043087 180 0.030
cytokine mediated signaling pathway GO:0019221 109 0.030
response to radiation GO:0009314 151 0.030
protein targeting GO:0006605 187 0.030
regulation of intracellular transport GO:0032386 195 0.030
regulation of proteolysis GO:0030162 293 0.030
innate immune response GO:0045087 178 0.030
regulation of ras protein signal transduction GO:0046578 155 0.030
purine containing compound catabolic process GO:0072523 411 0.030
positive regulation of ras gtpase activity GO:0032320 117 0.030
cell projection organization GO:0030030 252 0.029
regulation of nucleotide catabolic process GO:0030811 205 0.029
peptidyl serine modification GO:0018209 106 0.029
gtp catabolic process GO:0006184 237 0.029
long term memory GO:0007616 2 0.029
protein oligomerization GO:0051259 173 0.029
Human
response to inorganic substance GO:0010035 127 0.029
regulation of vasculature development GO:1901342 97 0.029
prostate gland development GO:0030850 3 0.029
somatic stem cell division GO:0048103 1 0.028
embryo development GO:0009790 123 0.028
Human
regulation of system process GO:0044057 101 0.028
Fly
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.028
angiogenesis GO:0001525 147 0.028
negative regulation of intracellular signal transduction GO:1902532 183 0.028
Human
membrane organization GO:0061024 292 0.028
lipid localization GO:0010876 106 0.028
post embryonic organ development GO:0048569 1 0.027
head development GO:0060322 108 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.027
tissue migration GO:0090130 119 0.027
multicellular organismal response to stress GO:0033555 1 0.027
stem cell differentiation GO:0048863 93 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.027
cellular lactam metabolic process GO:0072338 1 0.027
negative regulation of cell migration GO:0030336 102 0.027
forebrain regionalization GO:0021871 3 0.027
actin cytoskeleton organization GO:0030036 207 0.027
Human
response to oxidative stress GO:0006979 121 0.027
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.026
Human
organ morphogenesis GO:0009887 147 0.026
Human Fly
positive regulation of gtp catabolic process GO:0033126 166 0.026
metal ion transport GO:0030001 272 0.026
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.026
chemotaxis GO:0006935 157 0.026
Fly
defense response to virus GO:0051607 71 0.026
neuroblast division GO:0055057 1 0.026
positive regulation of glucocorticoid secretion GO:2000851 4 0.026
response to wounding GO:0009611 168 0.026
male genitalia development GO:0030539 1 0.026
oxidation reduction process GO:0055114 396 0.026
Human
blood circulation GO:0008015 113 0.026
regulation of dna metabolic process GO:0051052 153 0.026
Human
asymmetric neuroblast division GO:0055059 1 0.025
generation of neurons GO:0048699 152 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
growth GO:0040007 202 0.025
Human Fly
regulation of endopeptidase activity GO:0052548 170 0.025
positive regulation of secretion GO:0051047 116 0.025
developmental programmed cell death GO:0010623 3 0.025
regulation of cytoskeleton organization GO:0051493 177 0.025
positive regulation of cell development GO:0010720 92 0.025
regulation of endothelial cell migration GO:0010594 67 0.025
nucleoside catabolic process GO:0009164 408 0.025
serotonin uptake GO:0051610 2 0.025
response to hypoxia GO:0001666 96 0.025
positive regulation of protein transport GO:0051222 135 0.025
interspecies interaction between organisms GO:0044419 156 0.025
Human
erk1 and erk2 cascade GO:0070371 104 0.025
Fly
leukocyte activation GO:0045321 164 0.025
maintenance of location GO:0051235 112 0.025
response to transforming growth factor beta GO:0071559 94 0.025
intracellular protein transport GO:0006886 270 0.025
cartilage condensation GO:0001502 1 0.025
dephosphorylation GO:0016311 209 0.024
tube morphogenesis GO:0035239 95 0.024
digestive system development GO:0055123 75 0.024
Fly
cellular response to oxidative stress GO:0034599 85 0.024
regulation of intracellular protein transport GO:0033157 123 0.024
peptide hormone secretion GO:0030072 50 0.024
positive regulation of endothelial cell migration GO:0010595 39 0.024
regulation of nucleoside metabolic process GO:0009118 209 0.024
spermatid development GO:0007286 4 0.024
synaptic transmission GO:0007268 61 0.024
Fly
positive regulation of cell motility GO:2000147 177 0.024
Human
tissue morphogenesis GO:0048729 96 0.024
lipid biosynthetic process GO:0008610 177 0.024
detection of mechanical stimulus GO:0050982 4 0.024
vasculature development GO:0001944 181 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
Human
somatic muscle development GO:0007525 1 0.024
muscle system process GO:0003012 81 0.024
endodermal cell fate commitment GO:0001711 4 0.023
sensory perception of temperature stimulus GO:0050951 1 0.023
associative learning GO:0008306 1 0.023
Fly
positive regulation of cellular component movement GO:0051272 181 0.023
Human
cellular protein complex assembly GO:0043623 188 0.023
histone modification GO:0016570 251 0.023
negative regulation of epithelial cell proliferation GO:0050680 48 0.023
positive regulation of programmed cell death GO:0043068 249 0.023
response to decreased oxygen levels GO:0036293 96 0.023
cell substrate adhesion GO:0031589 132 0.023
positive regulation of gtpase activity GO:0043547 166 0.023
regulation of peptidyl serine phosphorylation GO:0033135 50 0.023
neurotrophin trk receptor signaling pathway GO:0048011 4 0.023
steroid metabolic process GO:0008202 94 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
regulation of peptidase activity GO:0052547 180 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.023
alpha amino acid metabolic process GO:1901605 72 0.023
small molecule biosynthetic process GO:0044283 157 0.023
stem cell development GO:0048864 69 0.023
positive regulation of hormone biosynthetic process GO:0046886 4 0.022
motor neuron axon guidance GO:0008045 2 0.022
anion transmembrane transport GO:0098656 76 0.022
positive regulation of mitotic cell cycle GO:0045931 60 0.022
Human
regulation of body fluid levels GO:0050878 99 0.022
brain development GO:0007420 97 0.022
glucose homeostasis GO:0042593 31 0.022
Human
chromatin modification GO:0016568 298 0.022
protein maturation GO:0051604 233 0.022
neurogenesis GO:0022008 169 0.022
wnt signaling pathway GO:0016055 156 0.022
digestive tract development GO:0048565 75 0.022
Fly
aortic valve morphogenesis GO:0003180 3 0.022
neuronal stem cell division GO:0036445 1 0.022
regulation of stem cell differentiation GO:2000736 56 0.022
response to drug GO:0042493 81 0.022
response to molecule of bacterial origin GO:0002237 82 0.022
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.022
epithelial cell development GO:0002064 34 0.021
response to fungus GO:0009620 4 0.021
neurotransmitter secretion GO:0007269 4 0.021
positive regulation of nucleotide catabolic process GO:0030813 185 0.021
luteinizing hormone secretion GO:0032275 1 0.021
regulation of male gonad development GO:2000018 4 0.021
compound eye development GO:0048749 1 0.021
Fly
negative regulation of phosphorylation GO:0042326 174 0.021
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 0.021
positive regulation of epithelial cell proliferation GO:0050679 65 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
Human
positive regulation of nervous system development GO:0051962 54 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
negative regulation of cell cycle GO:0045786 193 0.021
mesenchyme development GO:0060485 59 0.021
cellular response to abiotic stimulus GO:0071214 117 0.021
Human
salivary gland morphogenesis GO:0007435 4 0.021
neuron projection regeneration GO:0031102 1 0.021
organic acid biosynthetic process GO:0016053 97 0.021
limb bud formation GO:0060174 1 0.021
wound healing GO:0042060 115 0.021
regulation of binding GO:0051098 111 0.020
regulation of defense response GO:0031347 154 0.020
positive regulation of odontogenesis GO:0042482 3 0.020
neurological system process GO:0050877 163 0.020
Fly
spermatid differentiation GO:0048515 4 0.020
detection of stimulus involved in sensory perception GO:0050906 43 0.020
single organismal cell cell adhesion GO:0016337 148 0.020
regulation of glial cell differentiation GO:0045685 3 0.020
regulation of multi organism process GO:0043900 157 0.020
regulation of astrocyte differentiation GO:0048710 3 0.020
cell aggregation GO:0098743 1 0.020
heart development GO:0007507 95 0.020
Human

LTK disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.139
disease of cellular proliferation DOID:14566 174 0.059
cancer DOID:162 167 0.050
organ system cancer DOID:0050686 164 0.047
hematopoietic system disease DOID:74 100 0.039
disease of metabolism DOID:0014667 295 0.034
Human
musculoskeletal system disease DOID:17 223 0.032
bone disease DOID:0080001 88 0.024
connective tissue disease DOID:65 109 0.024
central nervous system disease DOID:331 186 0.023
nervous system disease DOID:863 431 0.023
sensory system disease DOID:0050155 203 0.023
eye and adnexa disease DOID:1492 150 0.023
eye disease DOID:5614 149 0.023
diabetes mellitus DOID:9351 31 0.023
type 2 diabetes mellitus DOID:9352 28 0.023
carbohydrate metabolism disease DOID:0050013 32 0.023
glucose metabolism disease DOID:4194 32 0.023
acquired metabolic disease DOID:0060158 58 0.023
inherited metabolic disorder DOID:655 242 0.022
Human