Homo sapiens

144 known processes

TAP2

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

(Aliases: D6S217E,ABC18,ABCB3,APT2,RING11,PSF2)

TAP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
antigen processing and presentation via mhc class ib GO:0002475 3 0.991
ribonucleoside monophosphate catabolic process GO:0009158 158 0.875
extracellular transport GO:0006858 4 0.874
intracellular transport of virus GO:0075733 14 0.845
intracellular transport of viral protein in host cell GO:0019060 4 0.807
intracellular protein transport in other organism involved in symbiotic interaction GO:0051708 4 0.796
negative regulation of leukocyte mediated cytotoxicity GO:0001911 5 0.785
Rat
ribonucleoside catabolic process GO:0042454 406 0.683
atp metabolic process GO:0046034 176 0.653
antigen processing and presentation of endogenous antigen GO:0019883 7 0.596
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.527
chemical homeostasis GO:0048878 306 0.527
purine nucleotide catabolic process GO:0006195 405 0.501
nucleoside triphosphate catabolic process GO:0009143 394 0.477
purine nucleoside triphosphate catabolic process GO:0009146 392 0.477
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.473
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.459
transport of virus GO:0046794 14 0.452
amide transport GO:0042886 76 0.446
interaction with host GO:0051701 42 0.440
purine ribonucleotide catabolic process GO:0009154 404 0.439
nucleoside catabolic process GO:0009164 408 0.434
natural killer cell mediated cytotoxicity GO:0042267 23 0.431
Rat
nucleoside monophosphate metabolic process GO:0009123 191 0.413
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.397
purine nucleoside catabolic process GO:0006152 398 0.391
nucleotide catabolic process GO:0009166 408 0.391
purine containing compound catabolic process GO:0072523 411 0.391
peptide transport GO:0015833 74 0.375
determination of adult lifespan GO:0008340 2 0.372
regulation by virus of viral protein levels in host cell GO:0046719 4 0.334
multi organism localization GO:1902579 14 0.328
multi organism transport GO:0044766 14 0.321
intracellular protein transport GO:0006886 270 0.288
regulation of multi organism process GO:0043900 157 0.263
nucleoside monophosphate catabolic process GO:0009125 159 0.260
regulation of viral process GO:0050792 103 0.253
ubiquitin dependent protein catabolic process GO:0006511 206 0.230
cytoplasmic transport GO:0016482 379 0.217
positive regulation of regulatory t cell differentiation GO:0045591 3 0.200
purine nucleoside monophosphate catabolic process GO:0009128 158 0.193
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.192
purine nucleoside triphosphate metabolic process GO:0009144 412 0.178
defense response GO:0006952 315 0.177
Rat
negative regulation of defense response GO:0031348 47 0.162
Rat
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.161
multi organism intracellular transport GO:1902583 14 0.153
regulation of defense response GO:0031347 154 0.151
Rat
post embryonic development GO:0009791 2 0.147
cellular response to dna damage stimulus GO:0006974 379 0.146
mitotic cell cycle GO:0000278 326 0.139
nucleoside triphosphate metabolic process GO:0009141 422 0.137
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.134
purine nucleoside monophosphate metabolic process GO:0009126 186 0.132
glycosyl compound catabolic process GO:1901658 413 0.129
multicellular organismal aging GO:0010259 3 0.122
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 2 0.122
immune effector process GO:0002252 159 0.115
Mouse Rat
purine ribonucleoside catabolic process GO:0046130 398 0.108
viral process GO:0016032 146 0.106
symbiont intracellular protein transport in host GO:0030581 4 0.104
regulation of immune response GO:0050776 201 0.104
Mouse Rat
mitotic cell cycle process GO:1903047 286 0.102
purine ribonucleoside metabolic process GO:0046128 437 0.101
regulation of immune effector process GO:0002697 91 0.100
Mouse Rat
regulation of leukocyte mediated immunity GO:0002703 38 0.099
Mouse Rat
organophosphate catabolic process GO:0046434 430 0.096
regulation of regulatory t cell differentiation GO:0045589 4 0.091
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 6 0.087
lymphocyte mediated immunity GO:0002449 48 0.086
Mouse Rat
mitotic spindle elongation GO:0000022 4 0.084
cell activation GO:0001775 213 0.082
leukocyte mediated immunity GO:0002443 59 0.082
Mouse Rat
t cell differentiation in thymus GO:0033077 4 0.080
positive regulation of developmental process GO:0051094 314 0.080
ribonucleoside triphosphate metabolic process GO:0009199 412 0.079
immune system development GO:0002520 195 0.077
cellular macromolecular complex assembly GO:0034622 324 0.076
hematopoietic or lymphoid organ development GO:0048534 186 0.068
spindle elongation GO:0051231 4 0.066
mononuclear cell proliferation GO:0032943 71 0.065
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.063
Mouse Rat
positive regulation of cell differentiation GO:0045597 211 0.062
positive regulation of immune system process GO:0002684 283 0.059
Mouse Rat
ribonucleotide catabolic process GO:0009261 405 0.057
leukocyte mediated cytotoxicity GO:0001909 27 0.057
Mouse Rat
multi organism cellular process GO:0044764 156 0.057
regulation of dendritic cell differentiation GO:2001198 3 0.057
positive regulation of innate immune response GO:0045089 79 0.056
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.055
Mouse Rat
centrosome organization GO:0051297 58 0.055
system process GO:0003008 349 0.054
negative regulation of lymphocyte mediated immunity GO:0002707 12 0.054
Rat
microtubule based process GO:0007017 210 0.053
regulation of leukocyte activation GO:0002694 115 0.053
positive regulation of leukocyte activation GO:0002696 80 0.050
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 2 0.050
immune response activating signal transduction GO:0002757 90 0.049
viral life cycle GO:0019058 132 0.045
microtubule organizing center organization GO:0031023 62 0.044
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.042
innate immune response GO:0045087 178 0.042
Rat
regulation of anatomical structure morphogenesis GO:0022603 286 0.042
cellular macromolecule catabolic process GO:0044265 380 0.041
negative regulation of leukocyte activation GO:0002695 26 0.041
cellular protein catabolic process GO:0044257 261 0.040
negative regulation of leukocyte mediated immunity GO:0002704 14 0.038
Rat
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.038
response to external biotic stimulus GO:0043207 261 0.036
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.035
t cell activation GO:0042110 99 0.034
anatomical structure homeostasis GO:0060249 100 0.033
immune response GO:0006955 307 0.031
Mouse Rat
negative regulation of developmental process GO:0051093 247 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.031
detection of stimulus GO:0051606 85 0.029
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.029
Mouse Rat
immune response regulating signaling pathway GO:0002764 97 0.027
positive regulation of immune response GO:0050778 159 0.026
Mouse Rat
import into cell GO:0098657 2 0.026
positive regulation of leukocyte mediated immunity GO:0002705 24 0.026
Mouse Rat
positive regulation of defense response GO:0031349 87 0.026
regulation of cellular protein catabolic process GO:1903362 96 0.026
natural killer cell mediated immunity GO:0002228 23 0.026
Rat
detection of chemical stimulus involved in sensory perception of taste GO:0050912 31 0.026
regulation of adaptive immune response GO:0002819 33 0.025
Mouse Rat
cell morphogenesis GO:0000902 296 0.024
mitotic spindle organization GO:0007052 27 0.024
cytokine production GO:0001816 247 0.024
regulatory t cell differentiation GO:0045066 5 0.024
regulation of interferon gamma production GO:0032649 36 0.024
inorganic ion import into cell GO:0099587 2 0.023
regulation of transmembrane transport GO:0034762 139 0.022
regeneration GO:0031099 4 0.022
mating GO:0007618 1 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
metal ion homeostasis GO:0055065 169 0.022
detection of stimulus involved in sensory perception GO:0050906 43 0.022
female gamete generation GO:0007292 2 0.022
ras protein signal transduction GO:0007265 73 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
lymphocyte differentiation GO:0030098 35 0.022
compound eye development GO:0048749 1 0.022
positive regulation of response to external stimulus GO:0032103 88 0.021
response to drug GO:0042493 81 0.021
regulation of cellular ketone metabolic process GO:0010565 50 0.021
tissue homeostasis GO:0001894 63 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
regulation of cell cycle process GO:0010564 266 0.021
regulation of cellular component biogenesis GO:0044087 281 0.020
oogenesis GO:0048477 2 0.020
sensory perception GO:0007600 103 0.020
regulation of leukocyte proliferation GO:0070663 67 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
protein localization to organelle GO:0033365 280 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
sensory perception of chemical stimulus GO:0007606 38 0.019
regulation of t cell activation GO:0050863 77 0.019
positive regulation of cell death GO:0010942 263 0.019
protein catabolic process GO:0030163 325 0.019
regulation of kinase activity GO:0043549 314 0.019
cellular ketone metabolic process GO:0042180 80 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
regulation of t cell tolerance induction GO:0002664 4 0.018
antigen processing and presentation of peptide antigen GO:0048002 18 0.018
negative regulation of immune system process GO:0002683 136 0.018
Rat
regulation of response to dna damage stimulus GO:2001020 94 0.018
cell projection organization GO:0030030 252 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
cellular amine metabolic process GO:0044106 41 0.017
cellular protein complex assembly GO:0043623 188 0.017
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.017
ion homeostasis GO:0050801 230 0.017
positive regulation of t cell mediated immunity GO:0002711 12 0.017
Mouse Rat
transmembrane transport GO:0055085 399 0.017
cell division GO:0051301 168 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
antigen processing and presentation GO:0019882 33 0.017
cd8 positive alpha beta t cell activation GO:0036037 3 0.017
blastoderm segmentation GO:0007350 2 0.017
regulation of cell migration GO:0030334 289 0.017
neurogenesis GO:0022008 169 0.016
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.016
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 5 0.016
response to biotic stimulus GO:0009607 276 0.016
Mouse
cell killing GO:0001906 34 0.016
Mouse Rat
locomotory behavior GO:0007626 1 0.016
positive regulation of catabolic process GO:0009896 310 0.016
spermatid differentiation GO:0048515 4 0.016
innate immune response activating signal transduction GO:0002758 48 0.015
cellular response to external stimulus GO:0071496 111 0.015
cellular component morphogenesis GO:0032989 314 0.015
regulation of t cell differentiation GO:0045580 19 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
protein oligomerization GO:0051259 173 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
positive regulation of secretion GO:0051047 116 0.015
regulation of protein catabolic process GO:0042176 155 0.015
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.015
purine nucleotide biosynthetic process GO:0006164 84 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
regulation of ion transport GO:0043269 189 0.014
neuromuscular junction development GO:0007528 3 0.014
glycosylation GO:0070085 71 0.014
pattern recognition receptor signaling pathway GO:0002221 48 0.014
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.014
Rat
peripheral nervous system development GO:0007422 2 0.014
amine metabolic process GO:0009308 44 0.014
lipid metabolic process GO:0006629 381 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
anion transport GO:0006820 161 0.014
regulation of cysteine type endopeptidase activity GO:2000116 127 0.014
regulation of cell cycle GO:0051726 393 0.014
single organism cellular localization GO:1902580 332 0.014
regulation of lymphocyte activation GO:0051249 103 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
cation homeostasis GO:0055080 189 0.013
regulation of cell cycle phase transition GO:1901987 126 0.013
segmentation GO:0035282 4 0.013
nucleotide biosynthetic process GO:0009165 109 0.013
regulation of cell development GO:0060284 161 0.013
positive regulation of cell activation GO:0050867 81 0.013
regulation of t cell proliferation GO:0042129 42 0.013
oocyte differentiation GO:0009994 2 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
response to abiotic stimulus GO:0009628 336 0.013
positive regulation of proteolysis GO:0045862 142 0.013
spermatid development GO:0007286 4 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
response to other organism GO:0051707 261 0.013
Mouse
regulation of cellular response to stress GO:0080135 244 0.013
sensory perception of bitter taste GO:0050913 28 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
cation transmembrane transport GO:0098655 238 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
developmental programmed cell death GO:0010623 3 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.012
glycoprotein metabolic process GO:0009100 110 0.012
negative regulation of transferase activity GO:0051348 124 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
protein targeting GO:0006605 187 0.012
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.012
Mouse Rat
oocyte development GO:0048599 1 0.012
cell projection assembly GO:0030031 126 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
ion transmembrane transport GO:0034220 338 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.012
divalent inorganic cation transport GO:0072511 158 0.012
regulation of transferase activity GO:0051338 355 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
memory GO:0007613 3 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.012
Mouse
cellular homeostasis GO:0019725 196 0.012
rho protein signal transduction GO:0007266 26 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
cell cycle checkpoint GO:0000075 117 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
cellular ion homeostasis GO:0006873 168 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
activation of cysteine type endopeptidase activity GO:0097202 57 0.011
anterior posterior axis specification GO:0009948 2 0.011
positive regulation of leukocyte differentiation GO:1902107 37 0.011
regulation of protein kinase activity GO:0045859 289 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
myoblast fusion GO:0007520 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
activation of innate immune response GO:0002218 55 0.011
cell part morphogenesis GO:0032990 137 0.011
regulation of cellular component movement GO:0051270 334 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
regulation of natural killer cell mediated immunity GO:0002715 16 0.011
Rat
response to activity GO:0014823 0 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
neuron differentiation GO:0030182 138 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
regulation of secretion by cell GO:1903530 177 0.011
protein autophosphorylation GO:0046777 123 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
positive regulation of cell cycle process GO:0090068 106 0.011
cellular lipid metabolic process GO:0044255 303 0.011
response to extracellular stimulus GO:0009991 85 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
interspecies interaction between organisms GO:0044419 156 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
sequestering of metal ion GO:0051238 24 0.010
salivary gland morphogenesis GO:0007435 4 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.010
Mouse Rat
negative regulation of protein modification process GO:0031400 200 0.010
regulation of lymphocyte mediated immunity GO:0002706 33 0.010
Mouse Rat
response to uv GO:0009411 73 0.010
cell adhesion GO:0007155 325 0.010
negative regulation of protein metabolic process GO:0051248 391 0.010
single organism membrane organization GO:0044802 268 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.010

TAP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 36 0.988
severe combined immunodeficiency DOID:627 10 0.988
combined t cell and b cell immunodeficiency DOID:628 12 0.988
immune system disease DOID:2914 155 0.988
cancer DOID:162 167 0.049
disease of cellular proliferation DOID:14566 174 0.049
organ system cancer DOID:0050686 164 0.049
sensory system disease DOID:0050155 203 0.012
nervous system disease DOID:863 431 0.012
disease of metabolism DOID:0014667 295 0.011
inherited metabolic disorder DOID:655 242 0.011
mhc class i deficiency DOID:0060009 3 0.001