Homo sapiens

148 known processes

HNF1A

HNF1 homeobox A

(Aliases: TCF-1,TCF1,MODY3,HNF-1A,IDDM20,HNF1,LFB1)

HNF1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
somatic stem cell maintenance GO:0035019 4 0.596
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.498
Rat
organ morphogenesis GO:0009887 147 0.425
Human Mouse
embryonic morphogenesis GO:0048598 85 0.394
Mouse
mesonephric duct development GO:0072177 3 0.374
regulation of cell differentiation GO:0045595 393 0.368
stem cell development GO:0048864 69 0.367
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.364
hindbrain development GO:0030902 3 0.363
mesonephric tubule formation GO:0072172 1 0.357
epithelium development GO:0060429 227 0.349
Human
neuron fate commitment GO:0048663 2 0.327
stem cell differentiation GO:0048863 93 0.294
regulation of anatomical structure morphogenesis GO:0022603 286 0.281
epithelial cell differentiation GO:0030855 141 0.278
negative regulation of multicellular organismal process GO:0051241 317 0.273
tube development GO:0035295 125 0.260
Human Mouse
nephron tubule formation GO:0072079 1 0.238
regulation of hormone levels GO:0010817 125 0.230
cellular amine metabolic process GO:0044106 41 0.227
gastrulation GO:0007369 51 0.225
Mouse
digestive tract morphogenesis GO:0048546 56 0.221
Mouse
regulation of locomotion GO:0040012 329 0.219
digestive tract development GO:0048565 75 0.218
Mouse
regulation of cell motility GO:2000145 299 0.218
amine metabolic process GO:0009308 44 0.215
regulation of kidney size GO:0035564 2 0.215
Human
micturition GO:0060073 3 0.212
enteroendocrine cell differentiation GO:0035883 6 0.212
regulation of cellular ketone metabolic process GO:0010565 50 0.203
tissue morphogenesis GO:0048729 96 0.200
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.196
chemical homeostasis GO:0048878 306 0.188
growth GO:0040007 202 0.188
globus pallidus development GO:0021759 1 0.187
positive regulation of developmental process GO:0051094 314 0.187
ectodermal placode development GO:0071696 1 0.181
cellular ketone metabolic process GO:0042180 80 0.179
post embryonic development GO:0009791 2 0.168
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.167
negative regulation of cell death GO:0060548 345 0.167
regulation of cell development GO:0060284 161 0.160
anatomical structure formation involved in morphogenesis GO:0048646 284 0.159
Mouse
peptide secretion GO:0002790 51 0.153
synaptic transmission involved in micturition GO:0060084 2 0.152
negative regulation of kidney development GO:0090185 2 0.152
response to hormone GO:0009725 175 0.150
response to oxygen containing compound GO:1901700 369 0.147
Mouse
blastocyst formation GO:0001825 3 0.146
specification of organ identity GO:0010092 3 0.145
regulation of wnt signaling pathway GO:0030111 123 0.140
Mouse
cellular amino acid metabolic process GO:0006520 116 0.139
peptide hormone secretion GO:0030072 50 0.139
endodermal cell fate commitment GO:0001711 4 0.136
cell cell signaling GO:0007267 155 0.134
metal ion transport GO:0030001 272 0.134
tube morphogenesis GO:0035239 95 0.133
Mouse
response to organonitrogen compound GO:0010243 156 0.128
positive regulation of cell proliferation GO:0008284 301 0.126
response to organic cyclic compound GO:0014070 204 0.126
hormone transport GO:0009914 68 0.124
nitrogen compound transport GO:0071705 191 0.123
positive regulation of cell development GO:0010720 92 0.122
regulation of cellular amino acid metabolic process GO:0006521 6 0.121
negative regulation of cell differentiation GO:0045596 171 0.119
negative regulation of apoptotic process GO:0043066 316 0.118
cellular homeostasis GO:0019725 196 0.118
system process GO:0003008 349 0.118
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.116
developmental programmed cell death GO:0010623 3 0.116
cell development GO:0048468 328 0.116
kidney development GO:0001822 53 0.114
Human
cardiovascular system development GO:0072358 262 0.113
cerebellum development GO:0021549 2 0.111
regulation of cell migration GO:0030334 289 0.111
response to nitrogen compound GO:1901698 184 0.107
endocrine pancreas development GO:0031018 11 0.106
Human Mouse
pancreatic a cell differentiation GO:0003310 1 0.105
single organism carbohydrate metabolic process GO:0044723 193 0.105
cell type specific apoptotic process GO:0097285 125 0.104
ameboidal type cell migration GO:0001667 135 0.104
enzyme linked receptor protein signaling pathway GO:0007167 303 0.102
Mouse
regulation of thyroid hormone generation GO:2000609 2 0.102
endodermal cell fate specification GO:0001714 4 0.100
regulation of mesonephros development GO:0061217 3 0.099
g protein coupled receptor signaling pathway GO:0007186 207 0.098
immune response GO:0006955 307 0.098
ion homeostasis GO:0050801 230 0.094
embryonic epithelial tube formation GO:0001838 4 0.094
cytoplasmic transport GO:0016482 379 0.093
glandular epithelial cell differentiation GO:0002067 6 0.093
secretion GO:0046903 254 0.091
regulation of stem cell differentiation GO:2000736 56 0.091
secretion by cell GO:0032940 226 0.088
regulation of apoptotic process involved in morphogenesis GO:1902337 1 0.086
cation transmembrane transport GO:0098655 238 0.085
epithelial cell proliferation GO:0050673 128 0.085
regulation of acetylcholine gated cation channel activity GO:1903048 1 0.084
ectodermal placode formation GO:0060788 1 0.084
apoptotic process involved in morphogenesis GO:0060561 3 0.082
divalent inorganic cation transport GO:0072511 158 0.081
renal system pattern specification GO:0072048 1 0.081
regulation of metanephros size GO:0035566 1 0.081
amide transport GO:0042886 76 0.081
cellular chemical homeostasis GO:0055082 180 0.081
positive regulation of cell differentiation GO:0045597 211 0.080
regulation of cellular amine metabolic process GO:0033238 11 0.080
regulation of ion transport GO:0043269 189 0.079
negative regulation of stem cell differentiation GO:2000737 22 0.079
response to estrogen GO:0043627 47 0.078
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 4 0.078
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.078
negative regulation of protein metabolic process GO:0051248 391 0.077
epithelial cell fate commitment GO:0072148 3 0.077
organ formation GO:0048645 3 0.077
segmentation GO:0035282 4 0.076
cell fate determination GO:0001709 3 0.076
regulation of protein localization GO:0032880 296 0.076
epithelium migration GO:0090132 119 0.076
regulation of cell cycle GO:0051726 393 0.076
carbohydrate metabolic process GO:0005975 207 0.076
endoderm development GO:0007492 33 0.074
cellular metal ion homeostasis GO:0006875 146 0.074
heart morphogenesis GO:0003007 48 0.074
circulatory system development GO:0072359 262 0.074
positive regulation of cellular component movement GO:0051272 181 0.074
regulation of protein kinase activity GO:0045859 289 0.074
chromatin modification GO:0016568 298 0.073
Mouse
inner ear morphogenesis GO:0042472 4 0.071
cation transport GO:0006812 331 0.070
digestive system development GO:0055123 75 0.069
Mouse
response to abiotic stimulus GO:0009628 336 0.068
branch elongation involved in ureteric bud branching GO:0060681 2 0.068
negative regulation of cellular protein metabolic process GO:0032269 353 0.067
response to alcohol GO:0097305 64 0.066
transmembrane transport GO:0055085 399 0.065
reactive oxygen species metabolic process GO:0072593 75 0.065
locomotory behavior GO:0007626 1 0.065
endoderm formation GO:0001706 33 0.065
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.063
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.063
kidney morphogenesis GO:0060993 19 0.063
Human
regulation of establishment of protein localization GO:0070201 242 0.063
organonitrogen compound biosynthetic process GO:1901566 200 0.063
Mouse
wnt signaling pathway GO:0016055 156 0.062
Mouse
regulation of insulin secretion GO:0050796 33 0.062
Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.061
regulation of kinase activity GO:0043549 314 0.061
cardiac cell fate determination GO:0060913 3 0.061
positive regulation of phosphorylation GO:0042327 394 0.060
actin filament based process GO:0030029 224 0.060
negative regulation of transport GO:0051051 176 0.059
calcium ion transport GO:0006816 147 0.059
negative regulation of acetylcholine gated cation channel activity GO:1903049 1 0.059
positive regulation of transferase activity GO:0051347 227 0.059
determination of adult lifespan GO:0008340 2 0.058
negative regulation of cell development GO:0010721 48 0.058
negative regulation of developmental process GO:0051093 247 0.058
blastoderm segmentation GO:0007350 2 0.058
striated muscle contraction GO:0006941 52 0.057
cell differentiation in spinal cord GO:0021515 1 0.057
negative regulation of programmed cell death GO:0043069 321 0.057
neuron differentiation GO:0030182 138 0.056
regulation of growth GO:0040008 165 0.056
formation of primary germ layer GO:0001704 42 0.056
Mouse
single organism cellular localization GO:1902580 332 0.056
multicellular organismal aging GO:0010259 3 0.055
positive regulation of protein phosphorylation GO:0001934 313 0.055
trophectodermal cell differentiation GO:0001829 3 0.055
response to metal ion GO:0010038 84 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
cell projection organization GO:0030030 252 0.054
regulation of protein serine threonine kinase activity GO:0071900 179 0.053
establishment of protein localization to organelle GO:0072594 172 0.053
response to lipid GO:0033993 206 0.053
positive regulation of locomotion GO:0040017 186 0.052
negative regulation of catalytic activity GO:0043086 335 0.052
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.051
pattern specification involved in kidney development GO:0061004 1 0.051
hormone secretion GO:0046879 65 0.050
response to monosaccharide GO:0034284 20 0.050
Mouse
cellular cation homeostasis GO:0030003 163 0.050
positive regulation of transport GO:0051050 336 0.050
response to wounding GO:0009611 168 0.049
negative regulation of intracellular signal transduction GO:1902532 183 0.049
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.049
mesodermal cell fate commitment GO:0001710 2 0.049
nephric duct development GO:0072176 4 0.049
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 1 0.048
blastocyst development GO:0001824 3 0.048
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.048
monocarboxylic acid biosynthetic process GO:0072330 67 0.048
Mouse
viral process GO:0016032 146 0.048
positive regulation of immune system process GO:0002684 283 0.047
purine containing compound catabolic process GO:0072523 411 0.047
regulation of transferase activity GO:0051338 355 0.047
blood vessel development GO:0001568 172 0.046
pancreas development GO:0031016 19 0.046
Human Mouse
limbic system development GO:0021761 3 0.046
cell morphogenesis GO:0000902 296 0.046
purine ribonucleoside metabolic process GO:0046128 437 0.045
intracellular protein transport GO:0006886 270 0.045
nephron morphogenesis GO:0072028 15 0.045
regulation of response to external stimulus GO:0032101 222 0.045
central nervous system development GO:0007417 123 0.045
carbohydrate homeostasis GO:0033500 31 0.044
regulation of cellular component biogenesis GO:0044087 281 0.044
regulation of ion transmembrane transport GO:0034765 132 0.044
cellular component morphogenesis GO:0032989 314 0.043
intracellular receptor signaling pathway GO:0030522 104 0.043
purine containing compound biosynthetic process GO:0072522 88 0.043
regulation of transmembrane transport GO:0034762 139 0.043
membrane organization GO:0061024 292 0.043
behavior GO:0007610 112 0.043
regulation of cellular component movement GO:0051270 334 0.043
positive regulation of kinase activity GO:0033674 204 0.042
sulfur compound metabolic process GO:0006790 101 0.042
inorganic ion transmembrane transport GO:0098660 231 0.042
muscle system process GO:0003012 81 0.042
regulation of transporter activity GO:0032409 82 0.042
negative regulation of protein modification process GO:0031400 200 0.042
regulation of peptide transport GO:0090087 62 0.042
Mouse
interspecies interaction between organisms GO:0044419 156 0.041
keratinization GO:0031424 2 0.041
response to hypoxia GO:0001666 96 0.041
tissue migration GO:0090130 119 0.041
nervous system development GO:0007399 293 0.041
regulation of immune response GO:0050776 201 0.041
generation of neurons GO:0048699 152 0.041
nucleocytoplasmic transport GO:0006913 176 0.041
negative regulation of cellular amine metabolic process GO:0033239 3 0.041
nephric duct formation GO:0072179 1 0.041
chromatin organization GO:0006325 351 0.040
Mouse
regulation of transmembrane transporter activity GO:0022898 74 0.040
regulation of canonical wnt signaling pathway GO:0060828 88 0.040
carboxylic acid biosynthetic process GO:0046394 97 0.040
Mouse
maintenance of location GO:0051235 112 0.040
negative regulation of phosphorus metabolic process GO:0010563 267 0.040
morphogenesis of a branching epithelium GO:0061138 20 0.040
negative regulation of proteolysis GO:0045861 132 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.039
epithelial cell migration GO:0010631 119 0.039
organic hydroxy compound biosynthetic process GO:1901617 71 0.039
Mouse
peptide transport GO:0015833 74 0.039
pituitary gland development GO:0021983 2 0.039
regulation of secretion GO:0051046 194 0.039
Mouse
vasculature development GO:0001944 181 0.039
oxidation reduction process GO:0055114 396 0.039
metencephalon development GO:0022037 2 0.039
purine nucleoside triphosphate metabolic process GO:0009144 412 0.039
response to drug GO:0042493 81 0.039
extraocular skeletal muscle development GO:0002074 1 0.038
ion transmembrane transport GO:0034220 338 0.038
cellular ion homeostasis GO:0006873 168 0.038
cation homeostasis GO:0055080 189 0.038
small molecule biosynthetic process GO:0044283 157 0.038
Mouse
glucose homeostasis GO:0042593 31 0.038
negative regulation of phosphate metabolic process GO:0045936 267 0.038
protein localization to organelle GO:0033365 280 0.038
epithelial cell development GO:0002064 34 0.038
embryonic camera type eye development GO:0031076 2 0.038
ectodermal placode morphogenesis GO:0071697 1 0.038
regulation of hormone secretion GO:0046883 57 0.037
Mouse
gland development GO:0048732 48 0.037
Mouse
positive regulation of cell migration GO:0030335 172 0.037
developmental growth GO:0048589 48 0.037
stem cell maintenance GO:0019827 19 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
right ventricular cardiac muscle tissue morphogenesis GO:0003221 2 0.037
positive regulation of neural precursor cell proliferation GO:2000179 2 0.036
negative regulation of cell proliferation GO:0008285 228 0.036
mapk cascade GO:0000165 288 0.036
cellular response to endogenous stimulus GO:0071495 336 0.036
negative regulation of protein processing GO:0010955 142 0.036
response to inorganic substance GO:0010035 127 0.036
mesonephric tubule morphogenesis GO:0072171 10 0.036
cell part morphogenesis GO:0032990 137 0.035
type b pancreatic cell development GO:0003323 4 0.035
protein targeting to nucleus GO:0044744 104 0.035
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.035
endothelial cell migration GO:0043542 86 0.035
positive regulation of cellular component organization GO:0051130 376 0.035
ureteric bud elongation GO:0060677 2 0.035
regulation of protein transport GO:0051223 213 0.034
regulation of anatomical structure size GO:0090066 101 0.034
Human
muscle structure development GO:0061061 98 0.034
protein targeting GO:0006605 187 0.034
regulation of endopeptidase activity GO:0052548 170 0.034
multi organism cellular process GO:0044764 156 0.034
nuclear transport GO:0051169 179 0.034
regulation of multi organism process GO:0043900 157 0.034
positive regulation of protein kinase activity GO:0045860 190 0.033
positive regulation of hydrolase activity GO:0051345 331 0.033
activation of protein kinase activity GO:0032147 90 0.033
metal ion homeostasis GO:0055065 169 0.033
neuromuscular junction development GO:0007528 3 0.033
somatostatin signaling pathway GO:0038170 1 0.033
negative regulation of cell motility GO:2000146 104 0.033
response to hexose GO:0009746 20 0.033
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 9 0.033
nucleoside catabolic process GO:0009164 408 0.032
rho protein signal transduction GO:0007266 26 0.032
regulation of epithelial cell migration GO:0010632 93 0.032
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.032
ventral spinal cord development GO:0021517 1 0.032
cardiac right ventricle morphogenesis GO:0003215 3 0.031
peptidyl tyrosine phosphorylation GO:0018108 170 0.031
protein localization to nucleus GO:0034504 136 0.031
heart formation GO:0060914 2 0.031
embryo development GO:0009790 123 0.031
Mouse
regulation of transcription involved in lymphatic endothelial cell fate commitment GO:0060849 2 0.031
covalent chromatin modification GO:0016569 254 0.031
regulation of heart contraction GO:0008016 50 0.031
muscle contraction GO:0006936 73 0.031
venous blood vessel development GO:0060841 2 0.031
eye photoreceptor cell differentiation GO:0001754 2 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.030
regulation of intracellular transport GO:0032386 195 0.030
endocrine system development GO:0035270 26 0.030
Human Mouse
regulation of reactive oxygen species metabolic process GO:2000377 41 0.030
regulation of proteolysis GO:0030162 293 0.030
branching morphogenesis of an epithelial tube GO:0048754 19 0.030
cell morphogenesis involved in differentiation GO:0000904 144 0.030
regulation of protein maturation GO:1903317 150 0.029
ureteric bud development GO:0001657 13 0.029
regulation of protein complex assembly GO:0043254 147 0.029
single organism membrane organization GO:0044802 268 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.029
regulation of cardioblast differentiation GO:0051890 4 0.029
cellular divalent inorganic cation homeostasis GO:0072503 128 0.029
single organism nuclear import GO:1902593 104 0.029
viral life cycle GO:0019058 132 0.029
epithelial tube morphogenesis GO:0060562 38 0.029
regulation of neurogenesis GO:0050767 82 0.029
positive regulation of ion transport GO:0043270 87 0.029
regeneration GO:0031099 4 0.029
oogenesis GO:0048477 2 0.028
renal system development GO:0072001 63 0.028
Human
protein catabolic process GO:0030163 325 0.028
cell fate specification GO:0001708 8 0.028
angiogenesis GO:0001525 147 0.028
taxis GO:0042330 157 0.028
inorganic cation transmembrane transport GO:0098662 194 0.028
head development GO:0060322 108 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
immune effector process GO:0002252 159 0.028
neural crest cell development GO:0014032 3 0.028
cytosolic calcium ion homeostasis GO:0051480 89 0.028
regulation of cell cycle process GO:0010564 266 0.028
regulation of cholesterol homeostasis GO:2000188 2 0.027
detection of stimulus GO:0051606 85 0.027
chemotaxis GO:0006935 157 0.027
cardiac atrium morphogenesis GO:0003209 7 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
nephron epithelium development GO:0072009 23 0.027
Human
regulation of calcium ion transport GO:0051924 79 0.027
negative regulation of phosphorylation GO:0042326 174 0.027
cellular lipid metabolic process GO:0044255 303 0.027
Mouse
actin cytoskeleton organization GO:0030036 207 0.027
apoptotic signaling pathway GO:0097190 268 0.027
glycosyl compound catabolic process GO:1901658 413 0.027
response to decreased oxygen levels GO:0036293 96 0.027
divalent inorganic cation homeostasis GO:0072507 136 0.027
anatomical structure homeostasis GO:0060249 100 0.027
Mouse
regulation of epithelial cell proliferation GO:0050678 113 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.027
positive regulation of cardioblast differentiation GO:0051891 2 0.027
regulation of secretion by cell GO:1903530 177 0.026
Mouse
small gtpase mediated signal transduction GO:0007264 78 0.026
positive regulation of nucleotide metabolic process GO:0045981 230 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
regulation of apoptotic signaling pathway GO:2001233 175 0.026
regulation of neural precursor cell proliferation GO:2000177 4 0.026
hair follicle morphogenesis GO:0031069 2 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
response to carbohydrate GO:0009743 21 0.026
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.026
protein processing GO:0016485 226 0.025
atrial cardiac muscle tissue morphogenesis GO:0055009 1 0.025
atrial cardiac muscle tissue development GO:0003228 1 0.025
reactive nitrogen species metabolic process GO:2001057 3 0.025
photoreceptor cell differentiation GO:0046530 2 0.025
positive regulation of homeostatic process GO:0032846 47 0.025
response to steroid hormone GO:0048545 80 0.025
regulation of methylation dependent chromatin silencing GO:0090308 3 0.025
monovalent inorganic cation transport GO:0015672 128 0.025
forebrain generation of neurons GO:0021872 3 0.025
protein maturation GO:0051604 233 0.025
regulation of peptide secretion GO:0002791 42 0.025
Mouse
positive regulation of mesonephros development GO:0061213 2 0.025
reproductive process GO:0022414 106 0.025
Human Mouse
hexose metabolic process GO:0019318 55 0.025
nucleoside triphosphate catabolic process GO:0009143 394 0.025
syncytium formation by plasma membrane fusion GO:0000768 2 0.025
regulation of homeostatic process GO:0032844 121 0.025
regulation of purine nucleotide catabolic process GO:0033121 205 0.025
response to glucose GO:0009749 19 0.025
Mouse
renal tubule development GO:0061326 19 0.025
Human
lipid metabolic process GO:0006629 381 0.025
Mouse
nephron tubule morphogenesis GO:0072078 13 0.025
single organism reproductive process GO:0044702 98 0.024
Human Mouse
endodermal cell differentiation GO:0035987 31 0.024
negative regulation of epithelial cell migration GO:0010633 38 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
mitotic cell cycle GO:0000278 326 0.024
negative regulation of apoptotic signaling pathway GO:2001234 97 0.024
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.024
nucleotide catabolic process GO:0009166 408 0.024
regulation of gastrulation GO:0010470 12 0.024
reactive oxygen species biosynthetic process GO:1903409 4 0.024
monosaccharide metabolic process GO:0005996 74 0.024
forebrain neuron differentiation GO:0021879 3 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
vesicle mediated transport GO:0016192 371 0.024
embryonic viscerocranium morphogenesis GO:0048703 1 0.024
nucleoside monophosphate metabolic process GO:0009123 191 0.024
nuclear import GO:0051170 106 0.024
morphogenesis of a branching structure GO:0001763 21 0.024
morphogenesis of an epithelium GO:0002009 60 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.024
female gamete generation GO:0007292 2 0.024
positive regulation of immune response GO:0050778 159 0.024
regulation of ion transmembrane transporter activity GO:0032412 72 0.024
positive regulation of humoral immune response GO:0002922 3 0.024
regulation of heart growth GO:0060420 4 0.024
regulation of intracellular protein transport GO:0033157 123 0.024
opioid receptor signaling pathway GO:0038003 4 0.024
embryonic camera type eye formation GO:0060900 2 0.024
postsynaptic membrane organization GO:0001941 2 0.024
cell growth GO:0016049 160 0.023
regulation of embryonic development GO:0045995 20 0.023
regulation of protein processing GO:0070613 150 0.023
alpha amino acid metabolic process GO:1901605 72 0.023
peptidyl lysine acetylation GO:0018394 101 0.023
negative regulation of wnt protein secretion GO:0061358 1 0.023
peripheral nervous system development GO:0007422 2 0.023
regulation of cell morphogenesis GO:0022604 153 0.023
embryonic organ development GO:0048568 36 0.023
axis elongation GO:0003401 4 0.023
spinal cord development GO:0021510 4 0.023
lipid biosynthetic process GO:0008610 177 0.023
Mouse
outflow tract septum morphogenesis GO:0003148 4 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
cytokine production GO:0001816 247 0.023
immune system development GO:0002520 195 0.023
regulation of cell growth GO:0001558 135 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
muscle organ development GO:0007517 56 0.022
positive regulation of cell death GO:0010942 263 0.022
endothelial cell fate commitment GO:0060839 3 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
sex differentiation GO:0007548 45 0.022
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
peptidyl tyrosine modification GO:0018212 170 0.022
ureteric bud morphogenesis GO:0060675 10 0.022
regulation of mapk cascade GO:0043408 262 0.022
protein acylation GO:0043543 138 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.022
negative regulation of protein maturation GO:1903318 142 0.022
regulation of cytokine production GO:0001817 232 0.022
ribose phosphate biosynthetic process GO:0046390 82 0.022
response to oxygen levels GO:0070482 100 0.022
insulin secretion GO:0030073 39 0.022
skeletal muscle tissue growth GO:0048630 2 0.022
negative regulation of cell cycle GO:0045786 193 0.022
negative regulation of cell migration GO:0030336 102 0.022
negative regulation of mitotic cell cycle GO:0045930 102 0.022
peptidyl lysine modification GO:0018205 144 0.022
regulation of ras protein signal transduction GO:0046578 155 0.022
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
blood circulation GO:0008015 113 0.021
protein oligomerization GO:0051259 173 0.021
atp catabolic process GO:0006200 157 0.021
positive regulation of gliogenesis GO:0014015 4 0.021
signal release GO:0023061 70 0.021
protein acetylation GO:0006473 116 0.021

HNF1A disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.378
acquired metabolic disease DOID:0060158 58 0.378
maturity onset diabetes of the young DOID:0050524 10 0.208
diabetes mellitus DOID:9351 31 0.208
carbohydrate metabolism disease DOID:0050013 32 0.208
glucose metabolism disease DOID:4194 32 0.208
type 2 diabetes mellitus DOID:9352 28 0.168
disease of cellular proliferation DOID:14566 174 0.098
cancer DOID:162 167 0.084
organ system cancer DOID:0050686 164 0.081
sensory system disease DOID:0050155 203 0.037
nervous system disease DOID:863 431 0.037
retinal disease DOID:5679 118 0.036
night blindness DOID:8499 10 0.036
eye and adnexa disease DOID:1492 150 0.036
eye disease DOID:5614 149 0.036
central nervous system disease DOID:331 186 0.028