Homo sapiens

17 known processes

CDC42BPG

CDC42 binding protein kinase gamma (DMPK-like)

(Aliases: DMPK2,MRCKgamma,HSMDPKIN,KAPPA-200)

CDC42BPG biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rho protein signal transduction GO:0007266 26 0.113
ribonucleoside catabolic process GO:0042454 406 0.113
ribonucleoside triphosphate metabolic process GO:0009199 412 0.105
small gtpase mediated signal transduction GO:0007264 78 0.102
actin filament based process GO:0030029 224 0.097
Human Fly
regulation of nucleotide catabolic process GO:0030811 205 0.094
purine containing compound catabolic process GO:0072523 411 0.094
purine nucleoside triphosphate metabolic process GO:0009144 412 0.093
purine nucleoside triphosphate catabolic process GO:0009146 392 0.085
organophosphate catabolic process GO:0046434 430 0.083
nucleoside triphosphate metabolic process GO:0009141 422 0.081
ras protein signal transduction GO:0007265 73 0.080
purine nucleotide catabolic process GO:0006195 405 0.080
ribonucleoside triphosphate catabolic process GO:0009203 391 0.079
glycosyl compound catabolic process GO:1901658 413 0.078
guanosine containing compound metabolic process GO:1901068 244 0.076
nucleoside catabolic process GO:0009164 408 0.075
regulation of purine nucleotide metabolic process GO:1900542 264 0.067
gtp metabolic process GO:0046039 239 0.067
purine nucleoside catabolic process GO:0006152 398 0.065
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.065
purine ribonucleoside metabolic process GO:0046128 437 0.064
regulation of nucleoside metabolic process GO:0009118 209 0.063
nucleotide catabolic process GO:0009166 408 0.062
purine ribonucleoside catabolic process GO:0046130 398 0.061
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.060
ribonucleotide catabolic process GO:0009261 405 0.057
nucleoside triphosphate catabolic process GO:0009143 394 0.056
nucleoside phosphate catabolic process GO:1901292 412 0.055
regulation of nucleotide metabolic process GO:0006140 269 0.055
regulation of gtpase activity GO:0043087 180 0.054
cellular ketone metabolic process GO:0042180 80 0.053
regulation of gtp catabolic process GO:0033124 180 0.053
single organism cell adhesion GO:0098602 179 0.053
Human
purine ribonucleotide catabolic process GO:0009154 404 0.053
guanosine containing compound catabolic process GO:1901069 239 0.052
single organismal cell cell adhesion GO:0016337 148 0.051
Human
positive regulation of gtpase activity GO:0043547 166 0.050
cell morphogenesis GO:0000902 296 0.049
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.049
cellular component morphogenesis GO:0032989 314 0.047
actin cytoskeleton organization GO:0030036 207 0.047
Human Fly
regulation of actin filament based process GO:0032970 141 0.046
Fly
post embryonic development GO:0009791 2 0.046
Worm
regulation of cytoskeleton organization GO:0051493 177 0.046
Fly
positive regulation of nucleotide catabolic process GO:0030813 185 0.046
regulation of cellular component biogenesis GO:0044087 281 0.044
Fly
single organism cellular localization GO:1902580 332 0.044
positive regulation of hydrolase activity GO:0051345 331 0.044
positive regulation of cellular component organization GO:0051130 376 0.043
regulation of cellular ketone metabolic process GO:0010565 50 0.043
regulation of purine nucleotide catabolic process GO:0033121 205 0.043
positive regulation of gtp catabolic process GO:0033126 166 0.043
regulation of ras protein signal transduction GO:0046578 155 0.042
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.042
regulation of small gtpase mediated signal transduction GO:0051056 156 0.041
cellular amine metabolic process GO:0044106 41 0.041
positive regulation of cellular catabolic process GO:0031331 284 0.040
cellular amino acid metabolic process GO:0006520 116 0.040
endomembrane system organization GO:0010256 196 0.039
regulation of actin cytoskeleton organization GO:0032956 116 0.039
Fly
positive regulation of nucleoside metabolic process GO:0045979 186 0.038
lipid metabolic process GO:0006629 381 0.038
biological adhesion GO:0022610 331 0.037
Human
membrane organization GO:0061024 292 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
single organism membrane organization GO:0044802 268 0.035
regulation of anatomical structure morphogenesis GO:0022603 286 0.035
Human
positive regulation of transport GO:0051050 336 0.035
regulation of ras gtpase activity GO:0032318 128 0.035
segmentation GO:0035282 4 0.034
positive regulation of protein phosphorylation GO:0001934 313 0.034
locomotory behavior GO:0007626 1 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
regulation of cell projection organization GO:0031344 107 0.033
positive regulation of catabolic process GO:0009896 310 0.033
positive regulation of nucleotide metabolic process GO:0045981 230 0.032
cell projection organization GO:0030030 252 0.032
microtubule based process GO:0007017 210 0.032
Human
neuromuscular junction development GO:0007528 3 0.031
multicellular organismal aging GO:0010259 3 0.030
protein localization to membrane GO:0072657 160 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
amine metabolic process GO:0009308 44 0.029
protein autophosphorylation GO:0046777 123 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
cell adhesion GO:0007155 325 0.029
Human
gtp catabolic process GO:0006184 237 0.028
nervous system development GO:0007399 293 0.028
Fly
blastoderm segmentation GO:0007350 2 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
regulation of cell cycle GO:0051726 393 0.028
microtubule cytoskeleton organization GO:0000226 176 0.027
Human
regulation of transferase activity GO:0051338 355 0.026
regulation of kinase activity GO:0043549 314 0.026
determination of adult lifespan GO:0008340 2 0.026
regulation of protein localization GO:0032880 296 0.025
establishment of protein localization to membrane GO:0090150 121 0.025
regulation of cell morphogenesis GO:0022604 153 0.025
negative regulation of protein metabolic process GO:0051248 391 0.025
cell division GO:0051301 168 0.024
positive regulation of cellular component biogenesis GO:0044089 158 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
Fly
cell projection assembly GO:0030031 126 0.023
protein localization to plasma membrane GO:0072659 93 0.023
mitotic cell cycle process GO:1903047 286 0.023
dephosphorylation GO:0016311 209 0.023
actin filament organization GO:0007015 128 0.023
Fly
cell junction organization GO:0034330 79 0.023
negative regulation of cellular component organization GO:0051129 235 0.023
morphogenesis of embryonic epithelium GO:0016331 4 0.022
regulation of cellular response to stress GO:0080135 244 0.022
spermatid differentiation GO:0048515 4 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
Human
regulation of protein kinase activity GO:0045859 289 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
regulation of cell adhesion GO:0030155 166 0.022
transmembrane transport GO:0055085 399 0.022
vesicle mediated transport GO:0016192 371 0.022
regulation of cell cycle process GO:0010564 266 0.022
neuroblast proliferation GO:0007405 4 0.022
negative regulation of phosphate metabolic process GO:0045936 267 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
positive regulation of locomotion GO:0040017 186 0.021
negative regulation of cellular protein metabolic process GO:0032269 353 0.021
positive regulation of organelle organization GO:0010638 195 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
enzyme linked receptor protein signaling pathway GO:0007167 303 0.021
anterior posterior axis specification GO:0009948 2 0.021
maintenance of location GO:0051235 112 0.021
cellular lipid metabolic process GO:0044255 303 0.021
spermatid development GO:0007286 4 0.021
cellular response to endogenous stimulus GO:0071495 336 0.020
regulation of proteolysis GO:0030162 293 0.020
cell development GO:0048468 328 0.020
Fly
regulation of cell differentiation GO:0045595 393 0.020
Human
regulation of rho gtpase activity GO:0032319 66 0.020
memory GO:0007613 3 0.020
chemical homeostasis GO:0048878 306 0.020
oogenesis GO:0048477 2 0.020
establishment of protein localization to plasma membrane GO:0090002 68 0.020
epithelium development GO:0060429 227 0.019
Human
ion transmembrane transport GO:0034220 338 0.019
cellular protein complex assembly GO:0043623 188 0.019
Fly
oocyte differentiation GO:0009994 2 0.019
metal ion transport GO:0030001 272 0.019
cell fate determination GO:0001709 3 0.019
cytoplasmic transport GO:0016482 379 0.019
regulation of protein complex assembly GO:0043254 147 0.019
Fly
epidermis morphogenesis GO:0048730 3 0.019
negative regulation of cell death GO:0060548 345 0.019
neurogenesis GO:0022008 169 0.018
Fly
plasma membrane organization GO:0007009 115 0.018
embryonic epithelial tube formation GO:0001838 4 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
positive regulation of cell motility GO:2000147 177 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
positive regulation of transferase activity GO:0051347 227 0.018
defense response GO:0006952 315 0.018
protein localization to organelle GO:0033365 280 0.018
nitrogen compound transport GO:0071705 191 0.018
regulation of response to external stimulus GO:0032101 222 0.018
somatic stem cell division GO:0048103 1 0.018
lipid biosynthetic process GO:0008610 177 0.017
positive regulation of mapk cascade GO:0043410 190 0.017
positive regulation of rho gtpase activity GO:0032321 56 0.017
positive regulation of kinase activity GO:0033674 204 0.017
protein catabolic process GO:0030163 325 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
glycerolipid metabolic process GO:0046486 107 0.017
actin filament based movement GO:0030048 17 0.017
regulation of mapk cascade GO:0043408 262 0.017
neuron differentiation GO:0030182 138 0.017
Fly
positive regulation of cell migration GO:0030335 172 0.017
cellular protein catabolic process GO:0044257 261 0.017
oocyte development GO:0048599 1 0.017
negative regulation of apoptotic process GO:0043066 316 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
growth GO:0040007 202 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
response to abiotic stimulus GO:0009628 336 0.016
monovalent inorganic cation transport GO:0015672 128 0.016
tripartite regional subdivision GO:0007351 2 0.016
positive regulation of developmental process GO:0051094 314 0.016
response to other organism GO:0051707 261 0.016
wnt signaling pathway GO:0016055 156 0.016
regulation of cell projection assembly GO:0060491 47 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
mitotic cell cycle GO:0000278 326 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
protein processing GO:0016485 226 0.015
intracellular protein transport GO:0006886 270 0.015
female gamete generation GO:0007292 2 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
organelle assembly GO:0070925 176 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
regulation of cellular component movement GO:0051270 334 0.015
regulation of intracellular transport GO:0032386 195 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
system process GO:0003008 349 0.015
response to oxygen containing compound GO:1901700 369 0.014
positive regulation of cell death GO:0010942 263 0.014
peripheral nervous system development GO:0007422 2 0.014
positive regulation of ras gtpase activity GO:0032320 117 0.014
cell part morphogenesis GO:0032990 137 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
regulation of cell motility GO:2000145 299 0.014
nuclear transport GO:0051169 179 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
cdc42 protein signal transduction GO:0032488 4 0.014
regeneration GO:0031099 4 0.014
regulation of cell development GO:0060284 161 0.014
keratinization GO:0031424 2 0.014
protein maturation GO:0051604 233 0.014
protein targeting GO:0006605 187 0.014
positive regulation of cytoskeleton organization GO:0051495 83 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.014
cation transmembrane transport GO:0098655 238 0.014
regulation of rho protein signal transduction GO:0035023 79 0.014
cytokinesis GO:0000910 96 0.014
regulation of protein catabolic process GO:0042176 155 0.014
ion homeostasis GO:0050801 230 0.014
regulation of growth GO:0040008 165 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
immune response GO:0006955 307 0.013
regulation of cytokine production GO:0001817 232 0.013
innate immune response GO:0045087 178 0.013
cell cell junction organization GO:0045216 69 0.013
metal ion homeostasis GO:0055065 169 0.013
stem cell division GO:0017145 2 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
regulation of actin filament polymerization GO:0030833 50 0.013
Fly
anion transport GO:0006820 161 0.013
positive regulation of immune system process GO:0002684 283 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
neural tube formation GO:0001841 3 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
compound eye development GO:0048749 1 0.013
cell cell signaling GO:0007267 155 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
cation transport GO:0006812 331 0.013
hair follicle morphogenesis GO:0031069 2 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
cell projection morphogenesis GO:0048858 129 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
regulation of anatomical structure size GO:0090066 101 0.012
Fly
lung alveolus development GO:0048286 4 0.012
single organism nuclear import GO:1902593 104 0.012
cell growth GO:0016049 160 0.012
cytokine production GO:0001816 247 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
adult locomotory behavior GO:0008344 1 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
epithelial cell differentiation GO:0030855 141 0.012
Human
mating GO:0007618 1 0.012
nuclear import GO:0051170 106 0.012
apoptotic signaling pathway GO:0097190 268 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
stress activated protein kinase signaling cascade GO:0031098 94 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
response to growth factor GO:0070848 205 0.012
cell substrate adhesion GO:0031589 132 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
chromatin organization GO:0006325 351 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
Human
regulation of protein processing GO:0070613 150 0.012
actin mediated cell contraction GO:0070252 12 0.012
glycoprotein metabolic process GO:0009100 110 0.012
regulation of protein maturation GO:1903317 150 0.012
protein localization to nucleus GO:0034504 136 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
organ formation GO:0048645 3 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
positive regulation of protein transport GO:0051222 135 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
regulation of peptidase activity GO:0052547 180 0.011
generation of neurons GO:0048699 152 0.011
Fly
regulation of endopeptidase activity GO:0052548 170 0.011
cell junction assembly GO:0034329 67 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
cell morphogenesis involved in differentiation GO:0000904 144 0.011
stress activated mapk cascade GO:0051403 93 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
positive regulation of cell projection organization GO:0031346 64 0.011
regulation of ion transport GO:0043269 189 0.011
regulation of cell division GO:0051302 116 0.011
secretion GO:0046903 254 0.011
detection of stimulus GO:0051606 85 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
actin filament bundle assembly GO:0051017 54 0.011
skin development GO:0043588 76 0.011
Human
response to cytokine GO:0034097 232 0.011
response to fungus GO:0009620 4 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
chromatin modification GO:0016568 298 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
regulation of jnk cascade GO:0046328 73 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
endocytosis GO:0006897 159 0.011
epidermal cell differentiation GO:0009913 45 0.011
Human
glycerophospholipid metabolic process GO:0006650 84 0.011
response to biotic stimulus GO:0009607 276 0.011
regulation of microtubule based process GO:0032886 74 0.011
atp metabolic process GO:0046034 176 0.011
peptidyl lysine modification GO:0018205 144 0.011
cation homeostasis GO:0055080 189 0.011
negative regulation of cell cycle GO:0045786 193 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
protein polymerization GO:0051258 71 0.011
Fly
positive regulation of cell cycle GO:0045787 140 0.010
phospholipid metabolic process GO:0006644 99 0.010
response to external biotic stimulus GO:0043207 261 0.010
primary neural tube formation GO:0014020 3 0.010
regulation of dephosphorylation GO:0035303 96 0.010
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.010
lamellipodium assembly GO:0030032 26 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
negative regulation of protein modification process GO:0031400 200 0.010
jnk cascade GO:0007254 80 0.010
endosomal transport GO:0016197 129 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.010
regulation of locomotion GO:0040012 329 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
circadian behavior GO:0048512 2 0.010
carbohydrate derivative biosynthetic process GO:1901137 207 0.010
protein ubiquitination GO:0016567 314 0.010
neuron development GO:0048666 113 0.010
Fly
neurological system process GO:0050877 163 0.010
steroid metabolic process GO:0008202 94 0.010
response to nitrogen compound GO:1901698 184 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
regulation of cell migration GO:0030334 289 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
inner ear morphogenesis GO:0042472 4 0.010
establishment of tissue polarity GO:0007164 3 0.010
regulation of defense response GO:0031347 154 0.010

CDC42BPG disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.020
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
eye and adnexa disease DOID:1492 150 0.014
central nervous system disease DOID:331 186 0.014
eye disease DOID:5614 149 0.014
inherited metabolic disorder DOID:655 242 0.014
retinal disease DOID:5679 118 0.013
musculoskeletal system disease DOID:17 223 0.013
disease of cellular proliferation DOID:14566 174 0.011
cancer DOID:162 167 0.011
organ system cancer DOID:0050686 164 0.011
urinary system disease DOID:18 40 0.011
retinal degeneration DOID:8466 89 0.011