Homo sapiens

36 known processes

UBE2E1

ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)

(Aliases: UBCH6)

UBE2E1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 110 1.000
protein ubiquitination GO:0016567 314 0.999
protein modification by small protein conjugation GO:0032446 342 0.998
histone monoubiquitination GO:0010390 20 0.993
protein monoubiquitination GO:0006513 39 0.988
histone h2b ubiquitination GO:0033523 8 0.985
protein k48 linked ubiquitination GO:0070936 38 0.973
histone ubiquitination GO:0016574 31 0.972
protein k11 linked ubiquitination GO:0070979 24 0.888
Human
protein autoubiquitination GO:0051865 37 0.808
isg15 protein conjugation GO:0032020 5 0.758
chromatin organization GO:0006325 351 0.729
modification dependent macromolecule catabolic process GO:0043632 212 0.611
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.608
protein k63 linked ubiquitination GO:0070534 31 0.594
Human
covalent chromatin modification GO:0016569 254 0.580
chromatin modification GO:0016568 298 0.496
cellular protein catabolic process GO:0044257 261 0.464
ubiquitin dependent protein catabolic process GO:0006511 206 0.452
protein catabolic process GO:0030163 325 0.411
protein k29 linked ubiquitination GO:0035519 4 0.404
modification dependent protein catabolic process GO:0019941 209 0.363
cellular macromolecule catabolic process GO:0044265 380 0.141
protein alkylation GO:0008213 74 0.141
response to external biotic stimulus GO:0043207 261 0.127
vesicle mediated transport GO:0016192 371 0.125
histone modification GO:0016570 251 0.123
post embryonic development GO:0009791 2 0.105
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 10 0.096
regulation of protein ubiquitination GO:0031396 95 0.092
regulation of cell cycle GO:0051726 393 0.090
cellular response to dna damage stimulus GO:0006974 379 0.084
proteasomal protein catabolic process GO:0010498 176 0.079
positive regulation of cellular component organization GO:0051130 376 0.074
interspecies interaction between organisms GO:0044419 156 0.073
maintenance of location GO:0051235 112 0.068
Fly
multi organism cellular process GO:0044764 156 0.057
positive regulation of organelle organization GO:0010638 195 0.056
regulation of cellular component biogenesis GO:0044087 281 0.056
cellular response to misfolded protein GO:0071218 2 0.055
cellular amino acid metabolic process GO:0006520 116 0.048
neuromuscular junction development GO:0007528 3 0.045
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.044
small molecule biosynthetic process GO:0044283 157 0.044
protein methylation GO:0006479 74 0.043
cell projection organization GO:0030030 252 0.041
protein k27 linked ubiquitination GO:0044314 4 0.038
multicellular organismal aging GO:0010259 3 0.038
response to abiotic stimulus GO:0009628 336 0.038
defense response GO:0006952 315 0.037
dna repair GO:0006281 198 0.037
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.036
regulation of cellular ketone metabolic process GO:0010565 50 0.036
ribonucleoside triphosphate catabolic process GO:0009203 391 0.035
response to biotic stimulus GO:0009607 276 0.035
cellular ketone metabolic process GO:0042180 80 0.034
positive regulation of immune response GO:0050778 159 0.034
organic acid biosynthetic process GO:0016053 97 0.034
locomotory behavior GO:0007626 1 0.033
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.033
cofactor metabolic process GO:0051186 87 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.032
macroautophagy GO:0016236 39 0.032
response to lipid GO:0033993 206 0.032
regulation of response to dna damage stimulus GO:2001020 94 0.032
blastocyst development GO:0001824 3 0.032
negative regulation of cell cycle GO:0045786 193 0.032
ion transmembrane transport GO:0034220 338 0.032
macromolecule methylation GO:0043414 97 0.031
positive regulation of developmental process GO:0051094 314 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
nerve development GO:0021675 4 0.030
regulation of cellular response to stress GO:0080135 244 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
regulation of mapk cascade GO:0043408 262 0.029
nucleoside phosphate catabolic process GO:1901292 412 0.028
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.028
nitrogen compound transport GO:0071705 191 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.027
purine containing compound catabolic process GO:0072523 411 0.027
cellular response to external stimulus GO:0071496 111 0.026
enzyme linked receptor protein signaling pathway GO:0007167 303 0.026
autophagy GO:0006914 88 0.026
response to other organism GO:0051707 261 0.026
response to bacterium GO:0009617 144 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
organelle assembly GO:0070925 176 0.026
negative regulation of multi organism process GO:0043901 92 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.025
response to cytokine GO:0034097 232 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
negative regulation of locomotion GO:0040013 118 0.025
response to drug GO:0042493 81 0.025
nucleotide catabolic process GO:0009166 408 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
regulation of cell migration GO:0030334 289 0.024
regulation of chromatin organization GO:1902275 56 0.023
mitotic cell cycle GO:0000278 326 0.023
response to steroid hormone GO:0048545 80 0.023
ribonucleotide catabolic process GO:0009261 405 0.022
methylation GO:0032259 106 0.022
positive regulation of chromosome organization GO:2001252 41 0.022
regulation of cell motility GO:2000145 299 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
cytoplasmic transport GO:0016482 379 0.022
positive regulation of chromatin modification GO:1903310 30 0.022
protein targeting GO:0006605 187 0.022
nuclear transport GO:0051169 179 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of chromosome organization GO:0033044 103 0.021
positive regulation of mapk cascade GO:0043410 190 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
negative regulation of catabolic process GO:0009895 104 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
lipid metabolic process GO:0006629 381 0.021
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.020
regulation of cellular component movement GO:0051270 334 0.020
positive regulation of histone modification GO:0031058 29 0.020
cellular component morphogenesis GO:0032989 314 0.020
cellular response to starvation GO:0009267 58 0.020
cell morphogenesis GO:0000902 296 0.020
rna processing GO:0006396 255 0.020
cellular response to heat GO:0034605 14 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
cellular amine metabolic process GO:0044106 41 0.019
spermatid differentiation GO:0048515 4 0.019
response to estrogen GO:0043627 47 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
response to oxygen containing compound GO:1901700 369 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
viral process GO:0016032 146 0.019
immune response GO:0006955 307 0.019
transmembrane transport GO:0055085 399 0.019
entry into host GO:0044409 25 0.019
regulation of cellular protein catabolic process GO:1903362 96 0.018
mitotic cell cycle process GO:1903047 286 0.018
cellular response to topologically incorrect protein GO:0035967 19 0.018
regulation of cell cycle process GO:0010564 266 0.018
endodermal cell fate commitment GO:0001711 4 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
regulation of response to external stimulus GO:0032101 222 0.018
single organism cellular localization GO:1902580 332 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
positive regulation of transport GO:0051050 336 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.018
determination of adult lifespan GO:0008340 2 0.018
positive regulation of phosphorylation GO:0042327 394 0.017
endocytosis GO:0006897 159 0.017
steroid metabolic process GO:0008202 94 0.017
ncrna metabolic process GO:0034660 108 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
formation of primary germ layer GO:0001704 42 0.017
fatty acid biosynthetic process GO:0006633 46 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.017
chemotaxis GO:0006935 157 0.017
adult locomotory behavior GO:0008344 1 0.017
nervous system development GO:0007399 293 0.017
regulation of actin cytoskeleton organization GO:0032956 116 0.017
monocarboxylic acid metabolic process GO:0032787 185 0.017
response to transforming growth factor beta GO:0071559 94 0.017
negative regulation of cell migration GO:0030336 102 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.017
amine metabolic process GO:0009308 44 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
response to topologically incorrect protein GO:0035966 29 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
regulation of actin filament based process GO:0032970 141 0.016
alcohol metabolic process GO:0006066 114 0.016
intracellular protein transport GO:0006886 270 0.016
ncrna processing GO:0034470 83 0.016
regulation of protein kinase activity GO:0045859 289 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
oogenesis GO:0048477 2 0.016
dolichol metabolic process GO:0019348 3 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
wnt signaling pathway GO:0016055 156 0.015
ras protein signal transduction GO:0007265 73 0.015
steroid biosynthetic process GO:0006694 46 0.015
oocyte development GO:0048599 1 0.015
secretion by cell GO:0032940 226 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
regulation of secretion GO:0051046 194 0.015
organic hydroxy compound biosynthetic process GO:1901617 71 0.015
positive regulation of immune system process GO:0002684 283 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
regulation of defense response GO:0031347 154 0.015
isoprenoid metabolic process GO:0006720 39 0.015
negative regulation of catalytic activity GO:0043086 335 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.015
positive regulation of catabolic process GO:0009896 310 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
positive regulation of protein ubiquitination GO:0031398 53 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
negative regulation of programmed cell death GO:0043069 321 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
negative regulation of immune system process GO:0002683 136 0.014
oocyte differentiation GO:0009994 2 0.014
lipid localization GO:0010876 106 0.014
Fly
negative regulation of cell proliferation GO:0008285 228 0.014
establishment of ribosome localization GO:0033753 4 0.014
cytokine mediated signaling pathway GO:0019221 109 0.014
regulation of endosome size GO:0051036 3 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
regulation of proteolysis GO:0030162 293 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
regulation of chromatin modification GO:1903308 51 0.014
nuclear export GO:0051168 69 0.014
positive regulation of transferase activity GO:0051347 227 0.014
regulation of ion transport GO:0043269 189 0.014
spermatid development GO:0007286 4 0.014
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.014
fatty acid metabolic process GO:0006631 115 0.014
response to growth factor GO:0070848 205 0.013
ribosomal subunit export from nucleus GO:0000054 4 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
cellular response to nutrient levels GO:0031669 69 0.013
regulation of intracellular transport GO:0032386 195 0.013
protein maturation GO:0051604 233 0.013
negative regulation of developmental process GO:0051093 247 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
organophosphate catabolic process GO:0046434 430 0.013
cell growth GO:0016049 160 0.013
mrna processing GO:0006397 133 0.013
response to hormone GO:0009725 175 0.013
response to organic cyclic compound GO:0014070 204 0.013
ribonucleoprotein complex export from nucleus GO:0071426 4 0.013
negative regulation of cellular component movement GO:0051271 106 0.013
female gamete generation GO:0007292 2 0.013
negative regulation of protein catabolic process GO:0042177 59 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.013
viral life cycle GO:0019058 132 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
cell division GO:0051301 168 0.013
protein localization to organelle GO:0033365 280 0.012
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
innate immune response GO:0045087 178 0.012
regulation of cellular response to growth factor stimulus GO:0090287 76 0.012
cell activation GO:0001775 213 0.012
gastrulation GO:0007369 51 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.012
purine nucleoside monophosphate catabolic process GO:0009128 158 0.012
regulation of protein complex assembly GO:0043254 147 0.012
cell part morphogenesis GO:0032990 137 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
regulation of membrane potential GO:0042391 95 0.012
mapk cascade GO:0000165 288 0.012
cellular lipid metabolic process GO:0044255 303 0.012
regulation of cell differentiation GO:0045595 393 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
motor neuron axon guidance GO:0008045 2 0.012
response to starvation GO:0042594 59 0.012
system process GO:0003008 349 0.012
regulation of transmembrane transport GO:0034762 139 0.012
regulation of tolerance induction GO:0002643 4 0.012
protein complex disassembly GO:0043241 52 0.012
regulation of anatomical structure size GO:0090066 101 0.012
neurotransmitter secretion GO:0007269 4 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.011
atp catabolic process GO:0006200 157 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
regulation of ribosome biogenesis GO:0090069 1 0.011
carbohydrate metabolic process GO:0005975 207 0.011
double strand break repair GO:0006302 101 0.011
actin filament organization GO:0007015 128 0.011
neuron differentiation GO:0030182 138 0.011
regulation of metal ion transport GO:0010959 120 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
cell fate determination GO:0001709 3 0.011
chromatin assembly or disassembly GO:0006333 78 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
immune effector process GO:0002252 159 0.011
immune system development GO:0002520 195 0.011
regulation of locomotion GO:0040012 329 0.011
stress activated mapk cascade GO:0051403 93 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
histone h3 k79 methylation GO:0034729 2 0.011
polyprenol biosynthetic process GO:0016094 1 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
regulation of defense response to virus GO:0050688 33 0.011
regulation of dna metabolic process GO:0051052 153 0.011
regulation of mrna export from nucleus GO:0010793 3 0.011
multi organism metabolic process GO:0044033 41 0.011
metal ion transport GO:0030001 272 0.011
regulation of autophagy GO:0010506 52 0.011
negative regulation of transport GO:0051051 176 0.010
secretion GO:0046903 254 0.010
peptidyl tyrosine modification GO:0018212 170 0.010
regulation of histone modification GO:0031056 47 0.010
negative regulation of autophagy GO:0010507 14 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
regulation of kinase activity GO:0043549 314 0.010
tube development GO:0035295 125 0.010
regulation of transporter activity GO:0032409 82 0.010
histone methylation GO:0016571 60 0.010
negative regulation of protein phosphorylation GO:0001933 140 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
regulation of immune response GO:0050776 201 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010

UBE2E1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.050
disease of cellular proliferation DOID:14566 174 0.050
central nervous system disease DOID:331 186 0.048
nervous system disease DOID:863 431 0.048
organ system cancer DOID:0050686 164 0.037
sensory system disease DOID:0050155 203 0.019
disease of metabolism DOID:0014667 295 0.013
retinal disease DOID:5679 118 0.013
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
inherited metabolic disorder DOID:655 242 0.011
neurodegenerative disease DOID:1289 102 0.010