Homo sapiens

20 known processes

UBE2E3

ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)

(Aliases: UBCH9,UbcM2)

UBE2E3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.907
protein k48 linked ubiquitination GO:0070936 38 0.803
protein k11 linked ubiquitination GO:0070979 24 0.754
protein polyubiquitination GO:0000209 110 0.527
protein ubiquitination GO:0016567 314 0.477
isg15 protein conjugation GO:0032020 5 0.474
Human
chromatin modification GO:0016568 298 0.259
Human
modification dependent macromolecule catabolic process GO:0043632 212 0.231
protein catabolic process GO:0030163 325 0.214
cellular protein catabolic process GO:0044257 261 0.209
protein monoubiquitination GO:0006513 39 0.189
Human
protein autoubiquitination GO:0051865 37 0.158
ubiquitin dependent protein catabolic process GO:0006511 206 0.130
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.123
protein k63 linked ubiquitination GO:0070534 31 0.122
proteasomal protein catabolic process GO:0010498 176 0.106
generation of neurons GO:0048699 152 0.098
post embryonic development GO:0009791 2 0.097
cellular macromolecule catabolic process GO:0044265 380 0.094
histone monoubiquitination GO:0010390 20 0.084
Human
regulation of cellular component biogenesis GO:0044087 281 0.077
response to abiotic stimulus GO:0009628 336 0.074
response to topologically incorrect protein GO:0035966 29 0.072
histone ubiquitination GO:0016574 31 0.072
Human
protein k29 linked ubiquitination GO:0035519 4 0.071
cellular ketone metabolic process GO:0042180 80 0.063
cellular amine metabolic process GO:0044106 41 0.063
regulation of cellular ketone metabolic process GO:0010565 50 0.059
cell development GO:0048468 328 0.058
regulation of cell differentiation GO:0045595 393 0.058
covalent chromatin modification GO:0016569 254 0.057
Human
chromatin organization GO:0006325 351 0.051
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.050
vacuole organization GO:0007033 44 0.049
cell projection organization GO:0030030 252 0.048
amine metabolic process GO:0009308 44 0.048
cell morphogenesis GO:0000902 296 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.045
neuromuscular junction development GO:0007528 3 0.045
positive regulation of developmental process GO:0051094 314 0.045
cellular component morphogenesis GO:0032989 314 0.045
cellular amino acid metabolic process GO:0006520 116 0.044
neuron differentiation GO:0030182 138 0.043
histone modification GO:0016570 251 0.041
Human
organelle assembly GO:0070925 176 0.040
chemical homeostasis GO:0048878 306 0.040
cell part morphogenesis GO:0032990 137 0.036
oogenesis GO:0048477 2 0.036
posttranscriptional regulation of gene expression GO:0010608 213 0.035
nervous system development GO:0007399 293 0.034
maintenance of location GO:0051235 112 0.033
Fly
blastoderm segmentation GO:0007350 2 0.033
response to hormone GO:0009725 175 0.033
enzyme linked receptor protein signaling pathway GO:0007167 303 0.032
system process GO:0003008 349 0.032
multicellular organismal aging GO:0010259 3 0.031
response to biotic stimulus GO:0009607 276 0.030
regulation of autophagy GO:0010506 52 0.030
regulation of cellular amine metabolic process GO:0033238 11 0.029
neuron development GO:0048666 113 0.029
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
response to organic cyclic compound GO:0014070 204 0.028
nuclear transport GO:0051169 179 0.028
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.028
modification dependent protein catabolic process GO:0019941 209 0.027
cellular response to misfolded protein GO:0071218 2 0.027
autophagy GO:0006914 88 0.027
female gamete generation GO:0007292 2 0.027
nucleoside monophosphate metabolic process GO:0009123 191 0.026
positive regulation of transport GO:0051050 336 0.026
ribonucleoside triphosphate catabolic process GO:0009203 391 0.026
cellular response to nutrient levels GO:0031669 69 0.025
response to starvation GO:0042594 59 0.025
cellular response to external stimulus GO:0071496 111 0.025
determination of adult lifespan GO:0008340 2 0.025
histone h2b ubiquitination GO:0033523 8 0.025
Human
cellular response to starvation GO:0009267 58 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
adult locomotory behavior GO:0008344 1 0.024
regulation of cell growth GO:0001558 135 0.024
regulation of protein ubiquitination GO:0031396 95 0.023
segmentation GO:0035282 4 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
response to external biotic stimulus GO:0043207 261 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
neurogenesis GO:0022008 169 0.022
single organism cellular localization GO:1902580 332 0.022
regulation of response to external stimulus GO:0032101 222 0.022
response to lipid GO:0033993 206 0.021
actin filament based process GO:0030029 224 0.021
regulation of cellular response to stress GO:0080135 244 0.021
small molecule biosynthetic process GO:0044283 157 0.021
response to inorganic substance GO:0010035 127 0.021
regulation of cell cycle process GO:0010564 266 0.021
nucleobase containing compound transport GO:0015931 51 0.020
purine ribonucleoside catabolic process GO:0046130 398 0.020
actin filament organization GO:0007015 128 0.020
memory GO:0007613 3 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
locomotory behavior GO:0007626 1 0.019
ras protein signal transduction GO:0007265 73 0.019
cell fate determination GO:0001709 3 0.019
ion homeostasis GO:0050801 230 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
cell morphogenesis involved in differentiation GO:0000904 144 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
response to other organism GO:0051707 261 0.019
spermatid differentiation GO:0048515 4 0.018
positive regulation of protein kinase activity GO:0045860 190 0.018
positive regulation of catabolic process GO:0009896 310 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
anterior posterior axis specification GO:0009948 2 0.018
er associated misfolded protein catabolic process GO:0071712 1 0.018
associative learning GO:0008306 1 0.018
response to oxygen containing compound GO:1901700 369 0.018
nerve development GO:0021675 4 0.018
cell growth GO:0016049 160 0.018
rna processing GO:0006396 255 0.018
response to alcohol GO:0097305 64 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.017
defense response GO:0006952 315 0.017
tripartite regional subdivision GO:0007351 2 0.017
response to steroid hormone GO:0048545 80 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
neuron projection development GO:0031175 106 0.017
regulation of growth GO:0040008 165 0.017
macroautophagy GO:0016236 39 0.017
nitrogen compound transport GO:0071705 191 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.016
oocyte development GO:0048599 1 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
hindbrain development GO:0030902 3 0.016
cell projection morphogenesis GO:0048858 129 0.016
cellular response to organic cyclic compound GO:0071407 127 0.016
nuclear import GO:0051170 106 0.016
intracellular protein transport GO:0006886 270 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
protein targeting GO:0006605 187 0.016
cellular homeostasis GO:0019725 196 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
activation of protein kinase activity GO:0032147 90 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
regulation of secretion GO:0051046 194 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
response to nutrient levels GO:0031667 81 0.015
establishment of organelle localization GO:0051656 59 0.015
response to estrogen GO:0043627 47 0.015
nucleotide catabolic process GO:0009166 408 0.015
positive regulation of cell growth GO:0030307 48 0.015
regulation of cell cycle GO:0051726 393 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
negative regulation of multi organism process GO:0043901 92 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
spermatid development GO:0007286 4 0.014
oocyte differentiation GO:0009994 2 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
atp catabolic process GO:0006200 157 0.014
carboxylic acid biosynthetic process GO:0046394 97 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
neurological system process GO:0050877 163 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
organic acid biosynthetic process GO:0016053 97 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
negative regulation of catabolic process GO:0009895 104 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
wnt signaling pathway GO:0016055 156 0.014
secretion GO:0046903 254 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
regulation of cell morphogenesis GO:0022604 153 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
response to transforming growth factor beta GO:0071559 94 0.013
regulation of organelle assembly GO:1902115 40 0.013
atp metabolic process GO:0046034 176 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
cell division GO:0051301 168 0.013
protein localization to organelle GO:0033365 280 0.013
protein targeting to nucleus GO:0044744 104 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
monovalent inorganic cation transport GO:0015672 128 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
stem cell differentiation GO:0048863 93 0.013
chemotaxis GO:0006935 157 0.013
cellular response to reactive oxygen species GO:0034614 50 0.013
response to fungus GO:0009620 4 0.013
regulation of cell development GO:0060284 161 0.013
positive regulation of organelle organization GO:0010638 195 0.012
central nervous system development GO:0007417 123 0.012
alcohol metabolic process GO:0006066 114 0.012
positive regulation of proteolysis GO:0045862 142 0.012
mesenchyme development GO:0060485 59 0.012
nucleoside triphosphate catabolic process GO:0009143 394 0.012
regulation of anatomical structure size GO:0090066 101 0.012
cellular lipid metabolic process GO:0044255 303 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
blood vessel morphogenesis GO:0048514 162 0.012
regulation of multi organism process GO:0043900 157 0.012
positive regulation of cell migration GO:0030335 172 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
organic hydroxy compound biosynthetic process GO:1901617 71 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
single organism nuclear import GO:1902593 104 0.012
monocarboxylic acid biosynthetic process GO:0072330 67 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
vesicle mediated transport GO:0016192 371 0.011
negative regulation of developmental process GO:0051093 247 0.011
rna interference GO:0016246 4 0.011
purine nucleoside monophosphate catabolic process GO:0009128 158 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
cytoplasmic transport GO:0016482 379 0.011
positive regulation of kinase activity GO:0033674 204 0.011
rna localization GO:0006403 41 0.011
intracellular mrna localization GO:0008298 1 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.011
anion transport GO:0006820 161 0.011
regulation of microtubule based process GO:0032886 74 0.011
regulation of nervous system development GO:0051960 88 0.011
cation transmembrane transport GO:0098655 238 0.011
mitotic cell cycle GO:0000278 326 0.011
purine containing compound catabolic process GO:0072523 411 0.011
protein k27 linked ubiquitination GO:0044314 4 0.011
purine nucleotide biosynthetic process GO:0006164 84 0.011
regulation of cellular component movement GO:0051270 334 0.011
taxis GO:0042330 157 0.011
metencephalon development GO:0022037 2 0.011
cranial nerve development GO:0021545 4 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
lipid localization GO:0010876 106 0.011
Fly
inorganic cation transmembrane transport GO:0098662 194 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
regulation of transferase activity GO:0051338 355 0.011
cellular response to dna damage stimulus GO:0006974 379 0.010
fatty acid metabolic process GO:0006631 115 0.010
response to growth factor GO:0070848 205 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.010
ribonucleoprotein complex biogenesis GO:0022613 116 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.010
cell activation GO:0001775 213 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.010
lipid biosynthetic process GO:0008610 177 0.010
lipid metabolic process GO:0006629 381 0.010
protein import GO:0017038 130 0.010

UBE2E3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.030
nervous system disease DOID:863 431 0.030
sensory system disease DOID:0050155 203 0.028
neurodegenerative disease DOID:1289 102 0.025
musculoskeletal system disease DOID:17 223 0.024
eye and adnexa disease DOID:1492 150 0.018
eye disease DOID:5614 149 0.016
retinal disease DOID:5679 118 0.013
disease of cellular proliferation DOID:14566 174 0.012
retinal degeneration DOID:8466 89 0.010