Homo sapiens

27 known processes

HSD17B11

hydroxysteroid (17-beta) dehydrogenase 11

(Aliases: SDR16C2,17BHSD11,RETSDR2,PAN1B,DHRS8)

HSD17B11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 381 0.112
positive regulation of transport GO:0051050 336 0.081
cellular amino acid metabolic process GO:0006520 116 0.064
post embryonic development GO:0009791 2 0.058
locomotory behavior GO:0007626 1 0.052
vesicle mediated transport GO:0016192 371 0.048
membrane organization GO:0061024 292 0.046
lipid biosynthetic process GO:0008610 177 0.046
multicellular organismal aging GO:0010259 3 0.045
ras protein signal transduction GO:0007265 73 0.045
small gtpase mediated signal transduction GO:0007264 78 0.045
cellular ketone metabolic process GO:0042180 80 0.044
amine metabolic process GO:0009308 44 0.043
positive regulation of hydrolase activity GO:0051345 331 0.043
organophosphate catabolic process GO:0046434 430 0.043
regulation of establishment of protein localization GO:0070201 242 0.041
regulation of secretion GO:0051046 194 0.040
ribonucleoside triphosphate metabolic process GO:0009199 412 0.039
ion transmembrane transport GO:0034220 338 0.038
positive regulation of phosphorylation GO:0042327 394 0.037
negative regulation of protein metabolic process GO:0051248 391 0.036
oogenesis GO:0048477 2 0.036
cellular amine metabolic process GO:0044106 41 0.036
regulation of transferase activity GO:0051338 355 0.036
negative regulation of catalytic activity GO:0043086 335 0.036
small molecule biosynthetic process GO:0044283 157 0.036
secretion GO:0046903 254 0.035
organonitrogen compound biosynthetic process GO:1901566 200 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
purine nucleoside triphosphate metabolic process GO:0009144 412 0.034
nucleoside catabolic process GO:0009164 408 0.034
carbohydrate derivative biosynthetic process GO:1901137 207 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
female gamete generation GO:0007292 2 0.031
regulation of secretion by cell GO:1903530 177 0.031
actin filament based process GO:0030029 224 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
cation transmembrane transport GO:0098655 238 0.031
regulation of protein localization GO:0032880 296 0.031
purine containing compound catabolic process GO:0072523 411 0.030
single organism membrane organization GO:0044802 268 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
carboxylic acid biosynthetic process GO:0046394 97 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.030
cellular lipid metabolic process GO:0044255 303 0.030
Human
regulation of protein transport GO:0051223 213 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
cation transport GO:0006812 331 0.029
purine nucleoside catabolic process GO:0006152 398 0.028
transmembrane transport GO:0055085 399 0.028
ribonucleotide catabolic process GO:0009261 405 0.028
regulation of cellular amine metabolic process GO:0033238 11 0.028
regulation of protein kinase activity GO:0045859 289 0.028
regulation of cellular ketone metabolic process GO:0010565 50 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.027
regulation of peptidase activity GO:0052547 180 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
positive regulation of nucleotide catabolic process GO:0030813 185 0.027
response to oxygen containing compound GO:1901700 369 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
glycosyl compound catabolic process GO:1901658 413 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.026
organic acid biosynthetic process GO:0016053 97 0.026
determination of adult lifespan GO:0008340 2 0.025
positive regulation of catabolic process GO:0009896 310 0.025
rho protein signal transduction GO:0007266 26 0.025
inorganic ion transmembrane transport GO:0098660 231 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
positive regulation of gtpase activity GO:0043547 166 0.024
mitotic cell cycle GO:0000278 326 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
protein localization to organelle GO:0033365 280 0.024
immune response GO:0006955 307 0.024
nucleotide catabolic process GO:0009166 408 0.024
organic hydroxy compound metabolic process GO:1901615 147 0.024
Human
apoptotic signaling pathway GO:0097190 268 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
regulation of cell cycle GO:0051726 393 0.024
memory GO:0007613 3 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
defense response GO:0006952 315 0.023
innate immune response GO:0045087 178 0.023
cation homeostasis GO:0055080 189 0.023
response to inorganic substance GO:0010035 127 0.023
regulation of nucleotide metabolic process GO:0006140 269 0.023
secretion by cell GO:0032940 226 0.023
cardiac muscle cell contraction GO:0086003 4 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
oxidation reduction process GO:0055114 396 0.022
response to hormone GO:0009725 175 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
response to abiotic stimulus GO:0009628 336 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
regulation of nucleotide catabolic process GO:0030811 205 0.022
organophosphate biosynthetic process GO:0090407 163 0.021
protein oligomerization GO:0051259 173 0.021
regulation of cell cycle process GO:0010564 266 0.021
system process GO:0003008 349 0.021
Human
single organism cellular localization GO:1902580 332 0.021
glycoprotein metabolic process GO:0009100 110 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
negative regulation of cell cycle GO:0045786 193 0.021
cellular component morphogenesis GO:0032989 314 0.021
regulation of kinase activity GO:0043549 314 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
negative regulation of multicellular organismal process GO:0051241 317 0.021
regeneration GO:0031099 4 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
cellular homeostasis GO:0019725 196 0.020
gtp catabolic process GO:0006184 237 0.020
activation of phospholipase a2 activity GO:0032431 2 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
metal ion transport GO:0030001 272 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
regulation of proteolysis GO:0030162 293 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
positive regulation of protein transport GO:0051222 135 0.020
mitotic cell cycle process GO:1903047 286 0.020
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
positive regulation of transferase activity GO:0051347 227 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
mapk cascade GO:0000165 288 0.019
cellular component disassembly GO:0022411 92 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
carbohydrate metabolic process GO:0005975 207 0.019
glycerolipid metabolic process GO:0046486 107 0.019
inorganic cation transmembrane transport GO:0098662 194 0.019
protein catabolic process GO:0030163 325 0.019
positive regulation of secretion GO:0051047 116 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
positive regulation of organelle organization GO:0010638 195 0.019
lipid catabolic process GO:0016042 84 0.019
alcohol metabolic process GO:0006066 114 0.019
Human
gtp metabolic process GO:0046039 239 0.018
ion homeostasis GO:0050801 230 0.018
positive regulation of gtp catabolic process GO:0033126 166 0.018
regulation of ras gtpase activity GO:0032318 128 0.018
regulation of cellular response to stress GO:0080135 244 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
protein processing GO:0016485 226 0.018
cell morphogenesis GO:0000902 296 0.018
monocarboxylic acid metabolic process GO:0032787 185 0.018
regulation of cell migration GO:0030334 289 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
cellular amide metabolic process GO:0043603 69 0.018
cellular chemical homeostasis GO:0055082 180 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
segmentation GO:0035282 4 0.018
cellular protein complex assembly GO:0043623 188 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
cellular response to oxygen containing compound GO:1901701 276 0.017
response to metal ion GO:0010038 84 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
anion transport GO:0006820 161 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
cytoplasmic transport GO:0016482 379 0.017
blastoderm segmentation GO:0007350 2 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
endomembrane system organization GO:0010256 196 0.017
endocytosis GO:0006897 159 0.017
protein localization to membrane GO:0072657 160 0.017
response to bacterium GO:0009617 144 0.017
cell cycle phase transition GO:0044770 173 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
positive regulation of secretion by cell GO:1903532 108 0.016
vesicle organization GO:0016050 62 0.016
protein homooligomerization GO:0051260 100 0.016
regulation of protein maturation GO:1903317 150 0.016
protein secretion GO:0009306 98 0.016
neuromuscular junction development GO:0007528 3 0.016
chemical homeostasis GO:0048878 306 0.016
protein maturation GO:0051604 233 0.016
epithelium development GO:0060429 227 0.016
organelle assembly GO:0070925 176 0.016
meiosis i GO:0007127 4 0.016
regulation of cellular component movement GO:0051270 334 0.016
nitrogen compound transport GO:0071705 191 0.016
intracellular protein transport GO:0006886 270 0.016
regulation of intracellular transport GO:0032386 195 0.016
organophosphate ester transport GO:0015748 32 0.015
mating GO:0007618 1 0.015
cell projection organization GO:0030030 252 0.015
autophagy GO:0006914 88 0.015
positive regulation of kinase activity GO:0033674 204 0.015
response to biotic stimulus GO:0009607 276 0.015
negative regulation of secretion GO:0051048 58 0.015
epithelial cell differentiation GO:0030855 141 0.015
organic anion transport GO:0015711 103 0.015
cardiovascular system development GO:0072358 262 0.015
adult locomotory behavior GO:0008344 1 0.015
regulation of anatomical structure size GO:0090066 101 0.015
positive regulation of ras gtpase activity GO:0032320 117 0.015
dephosphorylation GO:0016311 209 0.015
cellular protein catabolic process GO:0044257 261 0.015
cellular response to external stimulus GO:0071496 111 0.015
negative regulation of protein transport GO:0051224 75 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
cellular response to glucocorticoid stimulus GO:0071385 4 0.015
regulation of locomotion GO:0040012 329 0.015
nuclear transport GO:0051169 179 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
actin filament based movement GO:0030048 17 0.014
circadian behavior GO:0048512 2 0.014
cofactor metabolic process GO:0051186 87 0.014
regulation of actin filament based process GO:0032970 141 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
regulation of mapk cascade GO:0043408 262 0.014
negative regulation of transport GO:0051051 176 0.014
cytokine production GO:0001816 247 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
monocarboxylic acid biosynthetic process GO:0072330 67 0.014
negative regulation of cell cycle process GO:0010948 121 0.014
membrane lipid metabolic process GO:0006643 53 0.014
regulation of vesicle mediated transport GO:0060627 130 0.014
negative regulation of protein modification process GO:0031400 200 0.014
regulation of response to external stimulus GO:0032101 222 0.014
response to nitrogen compound GO:1901698 184 0.014
cytokine secretion GO:0050663 64 0.014
actin cytoskeleton organization GO:0030036 207 0.014
proteasomal protein catabolic process GO:0010498 176 0.014
positive regulation of cell death GO:0010942 263 0.014
endosomal transport GO:0016197 129 0.014
protein targeting GO:0006605 187 0.014
positive regulation of protein kinase activity GO:0045860 190 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
microtubule based process GO:0007017 210 0.014
regulation of protein processing GO:0070613 150 0.014
regulation of rho protein signal transduction GO:0035023 79 0.013
steroid metabolic process GO:0008202 94 0.013
cell development GO:0048468 328 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
double strand break repair GO:0006302 101 0.013
cell division GO:0051301 168 0.013
calcium ion transmembrane transport GO:0070588 76 0.013
response to other organism GO:0051707 261 0.013
epithelium migration GO:0090132 119 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
metal ion homeostasis GO:0055065 169 0.013
negative regulation of cell death GO:0060548 345 0.013
tissue migration GO:0090130 119 0.013
regulation of phospholipase a2 activity GO:0032429 4 0.013
cellular response to nutrient levels GO:0031669 69 0.013
regulation of cytokine production GO:0001817 232 0.013
negative regulation of protein maturation GO:1903318 142 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
negative regulation of proteolysis GO:0045861 132 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
angiogenesis GO:0001525 147 0.012
chemotaxis GO:0006935 157 0.012
blood vessel morphogenesis GO:0048514 162 0.012
regulation of cell motility GO:2000145 299 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
spermatid differentiation GO:0048515 4 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
glycoprotein biosynthetic process GO:0009101 91 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
glial cell migration GO:0008347 4 0.012
organelle fission GO:0048285 149 0.012
spermatid development GO:0007286 4 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
tissue regeneration GO:0042246 3 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.012
long term memory GO:0007616 2 0.012
negative regulation of secretion by cell GO:1903531 52 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
cellular cation homeostasis GO:0030003 163 0.012
cellular response to extracellular stimulus GO:0031668 72 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
response to nutrient levels GO:0031667 81 0.012
glycerolipid biosynthetic process GO:0045017 51 0.012
vasculature development GO:0001944 181 0.012
compound eye development GO:0048749 1 0.012
somatic muscle development GO:0007525 1 0.012
dna repair GO:0006281 198 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
regulation of protein targeting GO:1903533 91 0.012
peptide metabolic process GO:0006518 51 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
positive regulation of proteolysis GO:0045862 142 0.011
negative regulation of transferase activity GO:0051348 124 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
cellular protein complex disassembly GO:0043624 36 0.011
negative regulation of protein processing GO:0010955 142 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
rhythmic behavior GO:0007622 2 0.011
fatty acid metabolic process GO:0006631 115 0.011
response to external biotic stimulus GO:0043207 261 0.011
macromolecular complex disassembly GO:0032984 60 0.011
cell growth GO:0016049 160 0.011
epithelial cell proliferation GO:0050673 128 0.011
Human
regulation of mitotic cell cycle GO:0007346 189 0.011
regulation of protein stability GO:0031647 87 0.011
neuron development GO:0048666 113 0.011
protein complex disassembly GO:0043241 52 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
protein import GO:0017038 130 0.011
regulation of immune response GO:0050776 201 0.011
cell part morphogenesis GO:0032990 137 0.011
calcium ion transport GO:0006816 147 0.011
coenzyme metabolic process GO:0006732 65 0.011
membrane fusion GO:0061025 43 0.011
unsaturated fatty acid metabolic process GO:0033559 37 0.011
negative regulation of phospholipase activity GO:0010519 3 0.011
regulation of actin filament length GO:0030832 56 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
protein ubiquitination GO:0016567 314 0.011
positive regulation of immune system process GO:0002684 283 0.011
actin filament organization GO:0007015 128 0.011
striated muscle contraction GO:0006941 52 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.011
circulatory system development GO:0072359 262 0.011
nervous system development GO:0007399 293 0.011
organelle fusion GO:0048284 36 0.010
positive regulation of peptidase activity GO:0010952 88 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
tripartite regional subdivision GO:0007351 2 0.010
divalent inorganic cation transport GO:0072511 158 0.010
multi organism cellular process GO:0044764 156 0.010
diacylglycerol biosynthetic process GO:0006651 1 0.010
regulation of hormone levels GO:0010817 125 0.010
maintenance of location GO:0051235 112 0.010
negative regulation of cell cycle phase transition GO:1901988 89 0.010
actin polymerization or depolymerization GO:0008154 56 0.010
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
divalent metal ion transport GO:0070838 152 0.010
viral process GO:0016032 146 0.010
response to organonitrogen compound GO:0010243 156 0.010
response to lipid GO:0033993 206 0.010
ubiquitin dependent protein catabolic process GO:0006511 206 0.010
immune effector process GO:0002252 159 0.010
regulation of protein complex assembly GO:0043254 147 0.010
regulation of protein secretion GO:0050708 86 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010

HSD17B11 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.200
inherited metabolic disorder DOID:655 242 0.044
sensory system disease DOID:0050155 203 0.025
nervous system disease DOID:863 431 0.025
eye and adnexa disease DOID:1492 150 0.022
eye disease DOID:5614 149 0.019
musculoskeletal system disease DOID:17 223 0.018
central nervous system disease DOID:331 186 0.015
retinal disease DOID:5679 118 0.015
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013
acquired metabolic disease DOID:0060158 58 0.011
lysosomal storage disease DOID:3211 47 0.010
muscular disease DOID:0080000 114 0.010
muscle tissue disease DOID:66 113 0.010