Homo sapiens

29 known processes

SKA3

spindle and kinetochore associated complex subunit 3

(Aliases: RAMA1,C13orf3,MGC4832)

SKA3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric stem cell division GO:0098722 1 0.494
stem cell division GO:0017145 2 0.479
asymmetric neuroblast division GO:0055059 1 0.358
negative regulation of chromosome organization GO:2001251 48 0.285
somatic stem cell division GO:0048103 1 0.278
establishment or maintenance of neuroblast polarity GO:0045196 1 0.264
neuroblast division GO:0055057 1 0.229
regulation of proteasomal protein catabolic process GO:0061136 87 0.208
neuronal stem cell division GO:0036445 1 0.178
maintenance of cell polarity GO:0030011 2 0.174
post embryonic development GO:0009791 2 0.159
neuroblast proliferation GO:0007405 4 0.158
mitochondrial transport GO:0006839 60 0.155
regulation of mitosis GO:0007088 63 0.152
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.145
protein catabolic process GO:0030163 325 0.133
cell cycle g2 m phase transition GO:0044839 43 0.127
protein processing GO:0016485 226 0.126
mitochondrial fission GO:0000266 14 0.123
microtubule polymerization or depolymerization GO:0031109 37 0.117
negative regulation of protein metabolic process GO:0051248 391 0.110
spermatid differentiation GO:0048515 4 0.108
mitotic sister chromatid separation GO:0051306 18 0.101
dephosphorylation GO:0016311 209 0.101
nuclear division GO:0000280 128 0.100
protein targeting to mitochondrion GO:0006626 19 0.097
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.097
microtubule cytoskeleton organization GO:0000226 176 0.096
cell division GO:0051301 168 0.094
centrosome organization GO:0051297 58 0.093
negative regulation of neural precursor cell proliferation GO:2000178 1 0.093
establishment of protein localization to mitochondrion GO:0072655 22 0.093
mitotic nuclear division GO:0007067 119 0.088
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 8 0.087
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.086
regulation of microtubule based process GO:0032886 74 0.085
proteasomal protein catabolic process GO:0010498 176 0.084
chromosome separation GO:0051304 23 0.082
negative regulation of developmental process GO:0051093 247 0.082
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.080
regulation of protein catabolic process GO:0042176 155 0.079
positive regulation of cell cycle GO:0045787 140 0.079
regulation of cellular protein catabolic process GO:1903362 96 0.077
mitotic cell cycle process GO:1903047 286 0.077
negative regulation of cell differentiation GO:0045596 171 0.076
negative regulation of multicellular organismal process GO:0051241 317 0.076
protein dephosphorylation GO:0006470 81 0.076
regulation of mitotic sister chromatid segregation GO:0033047 27 0.076
spermatid development GO:0007286 4 0.076
regulation of mitotic sister chromatid separation GO:0010965 27 0.075
metaphase anaphase transition of cell cycle GO:0044784 21 0.075
regulation of cytoskeleton organization GO:0051493 177 0.074
cell cycle phase transition GO:0044770 173 0.074
mitotic sister chromatid segregation GO:0000070 53 0.071
negative regulation of cytokinesis GO:0032466 3 0.070
sister chromatid segregation GO:0000819 54 0.068
positive regulation of apoptotic process GO:0043065 246 0.068
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.068
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.066
regulation of cell differentiation GO:0045595 393 0.065
cytokinesis GO:0000910 96 0.065
protein targeting GO:0006605 187 0.065
regulation of chromosome organization GO:0033044 103 0.064
microtubule organizing center organization GO:0031023 62 0.064
mitotic cell cycle checkpoint GO:0007093 68 0.063
modification dependent protein catabolic process GO:0019941 209 0.063
negative regulation of mitotic cell cycle GO:0045930 102 0.061
organelle fission GO:0048285 149 0.061
regulation of sister chromatid segregation GO:0033045 27 0.061
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.060
mitotic cytokinesis GO:0000281 19 0.060
mitotic cell cycle GO:0000278 326 0.059
negative regulation of protein processing GO:0010955 142 0.058
negative regulation of cellular protein metabolic process GO:0032269 353 0.057
cell type specific apoptotic process GO:0097285 125 0.057
regulation of chromosome segregation GO:0051983 44 0.057
microtubule based process GO:0007017 210 0.057
regulation of phosphatase activity GO:0010921 81 0.056
regulation of nuclear division GO:0051783 65 0.056
regulation of dephosphorylation GO:0035303 96 0.055
regulation of neuroblast proliferation GO:1902692 3 0.055
modification dependent macromolecule catabolic process GO:0043632 212 0.054
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.053
protein stabilization GO:0050821 64 0.053
positive regulation of protein localization to nucleus GO:1900182 48 0.053
regulation of protein stability GO:0031647 87 0.053
negative regulation of catabolic process GO:0009895 104 0.052
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.052
protein localization to mitochondrion GO:0070585 25 0.052
negative regulation of cell proliferation GO:0008285 228 0.051
cellular protein catabolic process GO:0044257 261 0.050
regulation of cell division GO:0051302 116 0.049
regulation of cell cycle phase transition GO:1901987 126 0.049
ubiquitin dependent protein catabolic process GO:0006511 206 0.049
amine metabolic process GO:0009308 44 0.049
protein localization to organelle GO:0033365 280 0.048
positive regulation of cell death GO:0010942 263 0.048
cellular amino acid metabolic process GO:0006520 116 0.048
negative regulation of cellular catabolic process GO:0031330 83 0.048
intracellular protein transport GO:0006886 270 0.047
centriole replication GO:0007099 13 0.047
posttranscriptional regulation of gene expression GO:0010608 213 0.046
regulation of cytokinesis GO:0032465 45 0.046
cellular ketone metabolic process GO:0042180 80 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.045
negative regulation of stem cell proliferation GO:2000647 3 0.045
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.044
regulation of cell development GO:0060284 161 0.044
negative regulation of protein maturation GO:1903318 142 0.044
g2 m transition of mitotic cell cycle GO:0000086 41 0.044
negative regulation of cell cycle process GO:0010948 121 0.043
negative regulation of protein catabolic process GO:0042177 59 0.042
regulation of cellular ketone metabolic process GO:0010565 50 0.042
single organism cellular localization GO:1902580 332 0.041
cellular amine metabolic process GO:0044106 41 0.040
negative regulation of mitosis GO:0045839 24 0.039
cell cycle checkpoint GO:0000075 117 0.039
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.039
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.039
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
head development GO:0060322 108 0.038
positive regulation of programmed cell death GO:0043068 249 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
chromatin organization GO:0006325 351 0.037
nervous system development GO:0007399 293 0.037
regulation of protein maturation GO:1903317 150 0.037
establishment of protein localization to organelle GO:0072594 172 0.037
chromosome segregation GO:0007059 114 0.036
centriole assembly GO:0098534 14 0.036
mitotic cell cycle phase transition GO:0044772 162 0.036
negative regulation of sister chromatid segregation GO:0033046 17 0.035
positive regulation of mitotic cell cycle phase transition GO:1901992 19 0.035
cytoskeleton dependent cytokinesis GO:0061640 22 0.034
mitotic spindle assembly checkpoint GO:0007094 14 0.034
mitotic spindle checkpoint GO:0071174 18 0.034
multicellular organismal aging GO:0010259 3 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.033
regulation of protein processing GO:0070613 150 0.033
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.032
innate immune response GO:0045087 178 0.032
regulation of cell cycle GO:0051726 393 0.032
female gamete generation GO:0007292 2 0.032
negative regulation of proteolysis GO:0045861 132 0.031
spindle assembly checkpoint GO:0071173 17 0.031
negative regulation of cell division GO:0051782 31 0.030
immune response GO:0006955 307 0.030
regulation of cellular amino acid metabolic process GO:0006521 6 0.029
organelle assembly GO:0070925 176 0.029
wnt signaling pathway GO:0016055 156 0.029
regulation of protein localization to nucleus GO:1900180 85 0.029
regulation of cell cycle process GO:0010564 266 0.029
centrosome duplication GO:0051298 28 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.028
covalent chromatin modification GO:0016569 254 0.028
generation of neurons GO:0048699 152 0.026
central nervous system development GO:0007417 123 0.026
protein localization to nucleus GO:0034504 136 0.026
cell development GO:0048468 328 0.026
defense response GO:0006952 315 0.025
negative regulation of chromosome segregation GO:0051985 18 0.025
response to abiotic stimulus GO:0009628 336 0.025
positive regulation of cell cycle g2 m phase transition GO:1902751 8 0.024
negative regulation of cell development GO:0010721 48 0.024
negative regulation of cell cycle GO:0045786 193 0.024
reproductive process GO:0022414 106 0.024
regulation of neurogenesis GO:0050767 82 0.024
oogenesis GO:0048477 2 0.024
regulation of immune response GO:0050776 201 0.024
neuromuscular junction development GO:0007528 3 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
negative regulation of organelle organization GO:0010639 126 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
negative regulation of neurogenesis GO:0050768 26 0.022
ras protein signal transduction GO:0007265 73 0.022
membrane organization GO:0061024 292 0.022
brain development GO:0007420 97 0.022
neuron death GO:0070997 65 0.022
neuron apoptotic process GO:0051402 39 0.022
regulation of cell cycle g2 m phase transition GO:1902749 22 0.022
system process GO:0003008 349 0.021
regulation of mitotic cell cycle phase transition GO:1901990 118 0.021
protein maturation GO:0051604 233 0.021
cellular response to dna damage stimulus GO:0006974 379 0.021
anatomical structure formation involved in morphogenesis GO:0048646 284 0.021
negative regulation of cellular protein catabolic process GO:1903363 38 0.021
regulation of cellular component movement GO:0051270 334 0.021
embryo development GO:0009790 123 0.020
neurogenesis GO:0022008 169 0.020
negative regulation of cell cycle phase transition GO:1901988 89 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
lipid metabolic process GO:0006629 381 0.020
negative regulation of mitotic sister chromatid segregation GO:0033048 17 0.019
regulation of microtubule cytoskeleton organization GO:0070507 61 0.019
cell adhesion GO:0007155 325 0.019
regulation of protein kinase activity GO:0045859 289 0.019
regulation of proteolysis GO:0030162 293 0.019
regulation of protein localization GO:0032880 296 0.019
determination of adult lifespan GO:0008340 2 0.019
regulation of cytokine production GO:0001817 232 0.019
regulation of kinase activity GO:0043549 314 0.019
positive regulation of cellular catabolic process GO:0031331 284 0.019
behavior GO:0007610 112 0.019
regulation of cell migration GO:0030334 289 0.019
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 30 0.018
positive regulation of neuron death GO:1901216 14 0.018
regulation of mapk cascade GO:0043408 262 0.018
biological adhesion GO:0022610 331 0.018
positive regulation of organelle organization GO:0010638 195 0.018
cytoplasmic transport GO:0016482 379 0.018
single organism membrane organization GO:0044802 268 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.018
sensory organ development GO:0007423 52 0.018
cation transport GO:0006812 331 0.017
secretion GO:0046903 254 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
regeneration GO:0031099 4 0.017
response to biotic stimulus GO:0009607 276 0.017
transmembrane transport GO:0055085 399 0.017
establishment or maintenance of cell polarity GO:0007163 31 0.017
memory GO:0007613 3 0.017
positive regulation of neuron apoptotic process GO:0043525 8 0.017
macromolecule methylation GO:0043414 97 0.017
cytokine production GO:0001816 247 0.017
cardiac muscle cell contraction GO:0086003 4 0.017
activation of immune response GO:0002253 114 0.017
regulation of nervous system development GO:0051960 88 0.017
rho protein signal transduction GO:0007266 26 0.016
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.016
dna repair GO:0006281 198 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
epithelium migration GO:0090132 119 0.016
oxidation reduction process GO:0055114 396 0.016
developmental process involved in reproduction GO:0003006 66 0.016
segmentation GO:0035282 4 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
regulation of secretion GO:0051046 194 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
apoptotic signaling pathway GO:0097190 268 0.016
neuron differentiation GO:0030182 138 0.016
protein modification by small protein conjugation GO:0032446 342 0.015
regulation of secretion by cell GO:1903530 177 0.015
histone modification GO:0016570 251 0.015
epithelial cell migration GO:0010631 119 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
stem cell proliferation GO:0072089 25 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
methylation GO:0032259 106 0.015
exit from mitosis GO:0010458 10 0.015
response to growth factor GO:0070848 205 0.015
rna processing GO:0006396 255 0.015
chromatin modification GO:0016568 298 0.015
cell projection organization GO:0030030 252 0.015
blastoderm segmentation GO:0007350 2 0.015
negative regulation of nervous system development GO:0051961 28 0.015
locomotory behavior GO:0007626 1 0.015
regulation of cell growth GO:0001558 135 0.015
regulation of response to external stimulus GO:0032101 222 0.015
cellular macromolecule catabolic process GO:0044265 380 0.015
divalent inorganic cation transport GO:0072511 158 0.014
regulation of cell motility GO:2000145 299 0.014
cellular lipid metabolic process GO:0044255 303 0.014
response to oxygen containing compound GO:1901700 369 0.014
epithelium development GO:0060429 227 0.014
single organism reproductive process GO:0044702 98 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
secretion by cell GO:0032940 226 0.014
regulation of transferase activity GO:0051338 355 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
organonitrogen compound biosynthetic process GO:1901566 200 0.014
small molecule biosynthetic process GO:0044283 157 0.014
hair follicle morphogenesis GO:0031069 2 0.014
mitochondrion organization GO:0007005 156 0.014
cation transmembrane transport GO:0098655 238 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
circulatory system development GO:0072359 262 0.013
cell morphogenesis GO:0000902 296 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
regulation of multi organism process GO:0043900 157 0.013
regulation of neuron death GO:1901214 56 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
response to radiation GO:0009314 151 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
compound eye development GO:0048749 1 0.013
regulation of stem cell proliferation GO:0072091 15 0.013
positive regulation of transport GO:0051050 336 0.013
cell growth GO:0016049 160 0.013
spindle organization GO:0007051 53 0.013
chemical homeostasis GO:0048878 306 0.013
interspecies interaction between organisms GO:0044419 156 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
lipid biosynthetic process GO:0008610 177 0.013
anterior posterior axis specification GO:0009948 2 0.013
regulation of protein transport GO:0051223 213 0.013
associative learning GO:0008306 1 0.013
endomembrane system organization GO:0010256 196 0.013
vesicle mediated transport GO:0016192 371 0.013
metal ion transport GO:0030001 272 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.012
ion homeostasis GO:0050801 230 0.012
cellular chemical homeostasis GO:0055082 180 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
actin filament based movement GO:0030048 17 0.012
oocyte development GO:0048599 1 0.012
alcohol metabolic process GO:0006066 114 0.012
carbohydrate metabolic process GO:0005975 207 0.012
rhythmic behavior GO:0007622 2 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
response to fungus GO:0009620 4 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
protein methylation GO:0006479 74 0.012
negative regulation of cell death GO:0060548 345 0.012
peripheral nervous system development GO:0007422 2 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
ion transmembrane transport GO:0034220 338 0.012
actin mediated cell contraction GO:0070252 12 0.012
mapk cascade GO:0000165 288 0.012
positive regulation of defense response GO:0031349 87 0.012
response to nitrogen compound GO:1901698 184 0.012
sulfur compound metabolic process GO:0006790 101 0.012
protein localization to membrane GO:0072657 160 0.012
negative regulation of transport GO:0051051 176 0.011
regulation of ion transport GO:0043269 189 0.011
neurological system process GO:0050877 163 0.011
hemopoiesis GO:0030097 180 0.011
regulation of neuron apoptotic process GO:0043523 35 0.011
ameboidal type cell migration GO:0001667 135 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
viral life cycle GO:0019058 132 0.011
nuclear transport GO:0051169 179 0.011
actin cytoskeleton organization GO:0030036 207 0.011
nitrogen compound transport GO:0071705 191 0.011
cell projection assembly GO:0030031 126 0.011
nerve development GO:0021675 4 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
circadian behavior GO:0048512 2 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
negative regulation of immune system process GO:0002683 136 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
negative regulation of protein modification process GO:0031400 200 0.011
positive regulation of cytokine production GO:0001819 167 0.011
regulation of meiosis GO:0040020 3 0.011
motor neuron axon guidance GO:0008045 2 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
response to lipid GO:0033993 206 0.011
regulation of locomotion GO:0040012 329 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
angiogenesis GO:0001525 147 0.011
histone methylation GO:0016571 60 0.011
negative regulation of multi organism process GO:0043901 92 0.011
cardiac muscle contraction GO:0060048 34 0.010
response to other organism GO:0051707 261 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
tripartite regional subdivision GO:0007351 2 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
organic hydroxy compound metabolic process GO:1901615 147 0.010
organ morphogenesis GO:0009887 147 0.010
response to organonitrogen compound GO:0010243 156 0.010
protein ubiquitination GO:0016567 314 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
maintenance of location GO:0051235 112 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
cellular ion homeostasis GO:0006873 168 0.010

SKA3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.370
nervous system disease DOID:863 431 0.370
spinocerebellar degeneration DOID:2478 27 0.231
neurodegenerative disease DOID:1289 102 0.231
disease of metabolism DOID:0014667 295 0.025
sensory system disease DOID:0050155 203 0.018
inherited metabolic disorder DOID:655 242 0.018
musculoskeletal system disease DOID:17 223 0.015
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013
connective tissue disease DOID:65 109 0.012
bone disease DOID:0080001 88 0.011
immune system disease DOID:2914 155 0.011