Homo sapiens

0 known processes

TCF7L1

transcription factor 7-like 1 (T-cell specific, HMG-box)

(Aliases: TCF-3,TCF3)

TCF7L1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of developmental process GO:0051094 314 0.404
Human
regulation of cell differentiation GO:0045595 393 0.349
Human Mouse
cellular component morphogenesis GO:0032989 314 0.277
Human
circulatory system development GO:0072359 262 0.241
Human
cell development GO:0048468 328 0.239
Human Mouse
negative regulation of developmental process GO:0051093 247 0.235
Mouse
positive regulation of cell differentiation GO:0045597 211 0.224
Human
nervous system development GO:0007399 293 0.219
Zebrafish
cardiovascular system development GO:0072358 262 0.212
Human
morphogenesis of embryonic epithelium GO:0016331 4 0.200
anatomical structure formation involved in morphogenesis GO:0048646 284 0.181
organ morphogenesis GO:0009887 147 0.178
Zebrafish
small gtpase mediated signal transduction GO:0007264 78 0.172
biological adhesion GO:0022610 331 0.172
Human
negative regulation of multicellular organismal process GO:0051241 317 0.168
Human
cell projection organization GO:0030030 252 0.167
epithelium development GO:0060429 227 0.164
Zebrafish
blood vessel development GO:0001568 172 0.157
Human
vasculature development GO:0001944 181 0.156
Human
embryonic morphogenesis GO:0048598 85 0.146
Zebrafish
negative regulation of cell proliferation GO:0008285 228 0.146
blood vessel morphogenesis GO:0048514 162 0.145
cell morphogenesis GO:0000902 296 0.144
Human
cell adhesion GO:0007155 325 0.139
Human
negative regulation of cell death GO:0060548 345 0.138
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.136
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.136
single organism cell adhesion GO:0098602 179 0.127
Human
regulation of cell motility GO:2000145 299 0.126
Human
angiogenesis GO:0001525 147 0.124
tube development GO:0035295 125 0.123
Zebrafish
positive regulation of hydrolase activity GO:0051345 331 0.123
cellular response to growth factor stimulus GO:0071363 197 0.115
cell morphogenesis involved in differentiation GO:0000904 144 0.115
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.113
Human
positive regulation of locomotion GO:0040017 186 0.112
Human
renal system development GO:0072001 63 0.111
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.109
response to growth factor GO:0070848 205 0.109
positive regulation of programmed cell death GO:0043068 249 0.109
wnt signaling pathway GO:0016055 156 0.107
Human Zebrafish
ossification GO:0001503 121 0.107
Human
regulation of cell migration GO:0030334 289 0.106
Human
system process GO:0003008 349 0.106
digestive tract development GO:0048565 75 0.105
cellular response to endogenous stimulus GO:0071495 336 0.103
Human
nucleoside catabolic process GO:0009164 408 0.103
positive regulation of cell proliferation GO:0008284 301 0.103
Human Zebrafish
post embryonic development GO:0009791 2 0.100
segmentation GO:0035282 4 0.097
Zebrafish Mouse
positive regulation of cellular component organization GO:0051130 376 0.096
Human
regulation of nucleotide metabolic process GO:0006140 269 0.094
response to wounding GO:0009611 168 0.094
actin filament based process GO:0030029 224 0.091
regulation of cell cycle GO:0051726 393 0.091
Human
regulation of wnt signaling pathway GO:0030111 123 0.091
Human Zebrafish
ribonucleotide catabolic process GO:0009261 405 0.090
intracellular protein transport GO:0006886 270 0.089
Human
regulation of cell development GO:0060284 161 0.089
Human Mouse
negative regulation of cell differentiation GO:0045596 171 0.088
Mouse
cell type specific apoptotic process GO:0097285 125 0.087
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.084
somatic stem cell maintenance GO:0035019 4 0.082
Mouse
regulation of peptidase activity GO:0052547 180 0.082
Human
urogenital system development GO:0001655 65 0.082
ras protein signal transduction GO:0007265 73 0.082
digestive system development GO:0055123 75 0.082
purine nucleoside catabolic process GO:0006152 398 0.081
gastrulation GO:0007369 51 0.079
regulation of locomotion GO:0040012 329 0.078
Human
cellular ketone metabolic process GO:0042180 80 0.078
generation of neurons GO:0048699 152 0.077
Zebrafish
neuron differentiation GO:0030182 138 0.077
nucleoside phosphate catabolic process GO:1901292 412 0.074
positive regulation of transport GO:0051050 336 0.073
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.072
regulation of cellular component movement GO:0051270 334 0.072
Human
regulation of establishment of protein localization GO:0070201 242 0.072
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.072
Human
actin cytoskeleton organization GO:0030036 207 0.071
cellular amine metabolic process GO:0044106 41 0.071
purine ribonucleoside catabolic process GO:0046130 398 0.070
amine metabolic process GO:0009308 44 0.069
nucleoside triphosphate catabolic process GO:0009143 394 0.068
mapk cascade GO:0000165 288 0.068
skeletal system development GO:0001501 79 0.068
regulation of axon guidance GO:1902667 3 0.068
positive regulation of gtpase activity GO:0043547 166 0.068
pituitary gland development GO:0021983 2 0.068
epithelial cell differentiation GO:0030855 141 0.068
digestive tract morphogenesis GO:0048546 56 0.068
positive regulation of cellular amine metabolic process GO:0033240 7 0.067
positive regulation of nucleotide catabolic process GO:0030813 185 0.067
stem cell differentiation GO:0048863 93 0.067
Human Mouse
purine containing compound catabolic process GO:0072523 411 0.066
canonical wnt signaling pathway GO:0060070 116 0.065
Human
growth GO:0040007 202 0.065
Human
protein localization to organelle GO:0033365 280 0.064
neuron fate commitment GO:0048663 2 0.064
chemotaxis GO:0006935 157 0.064
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.064
neurogenesis GO:0022008 169 0.064
Zebrafish
regulation of purine nucleotide metabolic process GO:1900542 264 0.063
positive regulation of cellular component movement GO:0051272 181 0.063
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.063
negative regulation of cell adhesion GO:0007162 64 0.062
Human
regulation of actin filament based process GO:0032970 141 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
rho protein signal transduction GO:0007266 26 0.061
negative regulation of protein metabolic process GO:0051248 391 0.061
Human
regulation of response to external stimulus GO:0032101 222 0.061
taxis GO:0042330 157 0.061
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.061
regulation of cell morphogenesis GO:0022604 153 0.061
Human
tissue morphogenesis GO:0048729 96 0.061
Mouse
nuclear transport GO:0051169 179 0.060
Human
ameboidal type cell migration GO:0001667 135 0.060
purine nucleoside triphosphate metabolic process GO:0009144 412 0.060
positive regulation of apoptotic process GO:0043065 246 0.060
organophosphate catabolic process GO:0046434 430 0.059
ribonucleoside triphosphate catabolic process GO:0009203 391 0.059
cellular amino acid metabolic process GO:0006520 116 0.059
positive regulation of cell death GO:0010942 263 0.058
positive regulation of cell motility GO:2000147 177 0.058
Human
cell part morphogenesis GO:0032990 137 0.058
positive regulation of protein phosphorylation GO:0001934 313 0.057
ribonucleoside triphosphate metabolic process GO:0009199 412 0.057
purine ribonucleotide catabolic process GO:0009154 404 0.057
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.056
formation of primary germ layer GO:0001704 42 0.056
negative regulation of catalytic activity GO:0043086 335 0.056
Human
glycosyl compound catabolic process GO:1901658 413 0.056
regulation of epithelial cell proliferation GO:0050678 113 0.056
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.056
negative regulation of transport GO:0051051 176 0.056
regulation of proteolysis GO:0030162 293 0.056
Human
neuron development GO:0048666 113 0.055
regulation of gtpase activity GO:0043087 180 0.055
regulation of gtp catabolic process GO:0033124 180 0.054
purine nucleoside triphosphate catabolic process GO:0009146 392 0.054
regulation of cellular ketone metabolic process GO:0010565 50 0.054
signal transduction by phosphorylation GO:0023014 297 0.054
motor neuron axon guidance GO:0008045 2 0.053
nucleoside triphosphate metabolic process GO:0009141 422 0.053
negative regulation of phosphorus metabolic process GO:0010563 267 0.053
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.053
Human
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation GO:0044338 2 0.053
kidney development GO:0001822 53 0.053
cell fate determination GO:0001709 3 0.052
regulation of cell adhesion GO:0030155 166 0.052
Human
positive regulation of cell development GO:0010720 92 0.052
Human
negative regulation of apoptotic process GO:0043066 316 0.051
Human
tube morphogenesis GO:0035239 95 0.051
circulatory system process GO:0003013 113 0.051
regulation of mapk cascade GO:0043408 262 0.051
ribonucleoside catabolic process GO:0042454 406 0.050
regulation of protein transport GO:0051223 213 0.050
Human
cyclic nucleotide metabolic process GO:0009187 82 0.050
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.050
Human
gtp metabolic process GO:0046039 239 0.049
regulation of cytoskeleton organization GO:0051493 177 0.049
glial cell migration GO:0008347 4 0.049
regulation of sodium dependent phosphate transport GO:2000118 2 0.049
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.049
Human
cytoplasmic transport GO:0016482 379 0.049
Human
blastoderm segmentation GO:0007350 2 0.049
Mouse
morphogenesis of an epithelium GO:0002009 60 0.049
carbohydrate derivative biosynthetic process GO:1901137 207 0.049
Human
regulation of canonical wnt signaling pathway GO:0060828 88 0.048
Human
cytokine production GO:0001816 247 0.048
Human
response to abiotic stimulus GO:0009628 336 0.048
positive regulation of phosphorylation GO:0042327 394 0.048
osteoblast differentiation GO:0001649 92 0.047
Human
single organism cellular localization GO:1902580 332 0.047
organ formation GO:0048645 3 0.047
epithelial cell proliferation GO:0050673 128 0.047
protein targeting GO:0006605 187 0.047
cell growth GO:0016049 160 0.047
Human
spinal cord development GO:0021510 4 0.047
secretion GO:0046903 254 0.046
Human
sprouting angiogenesis GO:0002040 29 0.046
epithelial cell migration GO:0010631 119 0.046
negative regulation of cellular protein metabolic process GO:0032269 353 0.045
Human
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.045
positive regulation of catabolic process GO:0009896 310 0.045
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.045
neuron projection development GO:0031175 106 0.045
regeneration GO:0031099 4 0.045
nucleotide catabolic process GO:0009166 408 0.044
regulation of cysteine type endopeptidase activity GO:2000116 127 0.044
Human
regulation of cellular amine metabolic process GO:0033238 11 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.044
regulation of small gtpase mediated signal transduction GO:0051056 156 0.044
positive regulation of nucleoside metabolic process GO:0045979 186 0.043
anterior posterior axis specification GO:0009948 2 0.043
Mouse
oogenesis GO:0048477 2 0.043
forebrain generation of neurons GO:0021872 3 0.043
determination of adult lifespan GO:0008340 2 0.043
positive regulation of mapk cascade GO:0043410 190 0.043
establishment of protein localization to organelle GO:0072594 172 0.042
female gamete generation GO:0007292 2 0.042
cell substrate adhesion GO:0031589 132 0.042
regulation of cellular response to stress GO:0080135 244 0.042
regulation of endopeptidase activity GO:0052548 170 0.042
Human
prostate gland morphogenesis GO:0060512 1 0.041
mitotic cell cycle GO:0000278 326 0.041
regulation of stem cell differentiation GO:2000736 56 0.041
Human Mouse
regulation of intracellular protein transport GO:0033157 123 0.041
Human
purine ribonucleoside metabolic process GO:0046128 437 0.041
immune system development GO:0002520 195 0.041
Human
purine nucleotide catabolic process GO:0006195 405 0.041
canonical wnt signaling pathway involved in osteoblast differentiation GO:0044339 2 0.041
regulation of nucleocytoplasmic transport GO:0046822 98 0.040
Human
regulation of protein localization GO:0032880 296 0.040
Human
tissue migration GO:0090130 119 0.040
negative regulation of protein modification process GO:0031400 200 0.040
nucleocytoplasmic transport GO:0006913 176 0.040
Human
actin filament organization GO:0007015 128 0.040
stem cell development GO:0048864 69 0.040
Human Mouse
organonitrogen compound biosynthetic process GO:1901566 200 0.040
guanosine containing compound catabolic process GO:1901069 239 0.039
negative regulation of gastrulation GO:2000542 4 0.039
guanosine containing compound metabolic process GO:1901068 244 0.039
regulation of cell cycle process GO:0010564 266 0.039
Human
connective tissue development GO:0061448 39 0.039
vesicle mediated transport GO:0016192 371 0.039
multicellular organismal aging GO:0010259 3 0.038
epithelial tube morphogenesis GO:0060562 38 0.038
regulation of kinase activity GO:0043549 314 0.038
protein targeting to nucleus GO:0044744 104 0.038
gtp catabolic process GO:0006184 237 0.037
regulation of ras protein signal transduction GO:0046578 155 0.037
regulation of growth GO:0040008 165 0.037
Human
negative regulation of programmed cell death GO:0043069 321 0.037
Human
positive regulation of gtp catabolic process GO:0033126 166 0.037
regulation of epithelial cell migration GO:0010632 93 0.036
response to oxygen containing compound GO:1901700 369 0.036
wound healing GO:0042060 115 0.036
cell activation GO:0001775 213 0.036
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
negative regulation of cellular component organization GO:0051129 235 0.035
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.035
regulation of mitotic cell cycle GO:0007346 189 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
neuromuscular junction development GO:0007528 3 0.035
regulation of nucleoside metabolic process GO:0009118 209 0.035
negative regulation of ectodermal cell fate specification GO:0042666 1 0.034
regulation of transferase activity GO:0051338 355 0.034
cellular response to oxygen containing compound GO:1901701 276 0.034
anion transport GO:0006820 161 0.034
central nervous system development GO:0007417 123 0.034
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 186 0.034
Human
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.034
cell projection morphogenesis GO:0048858 129 0.034
regulation of stress activated mapk cascade GO:0032872 84 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
protein maturation GO:0051604 233 0.034
Human
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.034
embryo development GO:0009790 123 0.033
Zebrafish Mouse
retinal ganglion cell axon guidance GO:0031290 2 0.033
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.033
regulation of ras gtpase activity GO:0032318 128 0.033
negative regulation of cell migration GO:0030336 102 0.033
negative regulation of cell growth GO:0030308 83 0.033
positive regulation of proteolysis GO:0045862 142 0.033
defense response GO:0006952 315 0.033
mitotic cell cycle process GO:1903047 286 0.032
protein import GO:0017038 130 0.032
regulation of protein targeting GO:1903533 91 0.032
regulation of axon extension involved in axon guidance GO:0048841 2 0.032
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.032
Human
brain development GO:0007420 97 0.032
Zebrafish
regulation of cytoplasmic transport GO:1903649 149 0.032
Human
cation transport GO:0006812 331 0.032
negative regulation of intracellular signal transduction GO:1902532 183 0.032
chemical homeostasis GO:0048878 306 0.032
Human
ion transmembrane transport GO:0034220 338 0.032
regulation of nervous system development GO:0051960 88 0.032
response to cytokine GO:0034097 232 0.032
Human
neuron projection regeneration GO:0031102 1 0.032
positive regulation of ras gtpase activity GO:0032320 117 0.031
epithelium migration GO:0090132 119 0.031
positive regulation of mesenchymal stem cell differentiation GO:2000741 4 0.031
morphogenesis of a polarized epithelium GO:0001738 3 0.031
protein processing GO:0016485 226 0.031
Human
muscle structure development GO:0061061 98 0.031
Human
negative regulation of epithelial cell proliferation GO:0050680 48 0.031
protein catabolic process GO:0030163 325 0.031
regulation of actin cytoskeleton organization GO:0032956 116 0.030
negative regulation of cell fate commitment GO:0010454 3 0.030
hemopoiesis GO:0030097 180 0.030
Human
positive regulation of immune system process GO:0002684 283 0.030
Human
regulation of nucleotide catabolic process GO:0030811 205 0.030
negative regulation of gliogenesis GO:0014014 3 0.030
positive regulation of transferase activity GO:0051347 227 0.030
protein localization to nucleus GO:0034504 136 0.030
pattern specification process GO:0007389 43 0.030
Zebrafish Mouse
positive regulation of cell migration GO:0030335 172 0.030
Human
positive regulation of epithelial cell proliferation GO:0050679 65 0.029
endodermal cell fate specification GO:0001714 4 0.029
divalent inorganic cation transport GO:0072511 158 0.029
negative regulation of embryonic development GO:0045992 4 0.029
cellular macromolecule catabolic process GO:0044265 380 0.029
regulation of cellular response to growth factor stimulus GO:0090287 76 0.029
head development GO:0060322 108 0.029
Zebrafish
regulation of protein kinase activity GO:0045859 289 0.029
neural tube formation GO:0001841 3 0.028
blood circulation GO:0008015 113 0.028
regulation of protein import into nucleus GO:0042306 78 0.028
negative regulation of hydrolase activity GO:0051346 182 0.028
Human
negative regulation of glomerulus development GO:0090194 2 0.028
single organismal cell cell adhesion GO:0016337 148 0.028
Human
regulation of angiogenesis GO:0045765 92 0.028
regulation of cell growth GO:0001558 135 0.028
Human
response to lipid GO:0033993 206 0.027
Human
protein ubiquitination GO:0016567 314 0.027
anterior posterior axis specification embryo GO:0008595 2 0.027
Mouse
retina vasculature development in camera type eye GO:0061298 3 0.027
regulation of ectodermal cell fate specification GO:0042665 1 0.027
lipid biosynthetic process GO:0008610 177 0.027
positive regulation of peptidase activity GO:0010952 88 0.027
chromatin modification GO:0016568 298 0.027
Human
organophosphate biosynthetic process GO:0090407 163 0.027
positive regulation of stem cell differentiation GO:2000738 29 0.027
Human
endocytosis GO:0006897 159 0.027
patterning of blood vessels GO:0001569 2 0.026
dephosphorylation GO:0016311 209 0.026
protein import into nucleus GO:0006606 104 0.026
response to axon injury GO:0048678 1 0.026
apoptotic signaling pathway GO:0097190 268 0.026
Human
positive regulation of organelle organization GO:0010638 195 0.026
primary neural tube formation GO:0014020 3 0.026
negative regulation of phosphorylation GO:0042326 174 0.026
endodermal cell fate commitment GO:0001711 4 0.026
spemann organizer formation GO:0060061 1 0.026
cellular response to dna damage stimulus GO:0006974 379 0.026
heart development GO:0007507 95 0.026
sensory organ development GO:0007423 52 0.025
Zebrafish
negative regulation of cell fate specification GO:0009996 3 0.025
negative regulation of cell cycle GO:0045786 193 0.025
Human
transmembrane transport GO:0055085 399 0.025
regulation of endothelial cell migration GO:0010594 67 0.025
purine ribonucleotide biosynthetic process GO:0009152 79 0.025
negative regulation of immune system process GO:0002683 136 0.025
locomotory behavior GO:0007626 1 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
prostate gland development GO:0030850 3 0.025
regulation of neurogenesis GO:0050767 82 0.025
reproductive process GO:0022414 106 0.025
metal ion transport GO:0030001 272 0.025
covalent chromatin modification GO:0016569 254 0.025
Human
negative regulation of cell motility GO:2000146 104 0.025
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.025
cellular response to nitrogen compound GO:1901699 144 0.025
heart formation GO:0060914 2 0.025
hindbrain development GO:0030902 3 0.025
Zebrafish
regulation of cell projection organization GO:0031344 107 0.024
negative regulation of wnt signaling pathway GO:0030178 69 0.024
Human Zebrafish
secretion by cell GO:0032940 226 0.024
Human
peripheral nervous system development GO:0007422 2 0.024
stress activated mapk cascade GO:0051403 93 0.024
regulation of defense response GO:0031347 154 0.024
response to hormone GO:0009725 175 0.024
Human
regulation of cell cell adhesion GO:0022407 57 0.024
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.024
kidney epithelium development GO:0072073 25 0.024
mesenchyme development GO:0060485 59 0.023
Human
negative regulation of growth GO:0045926 97 0.023
nuclear import GO:0051170 106 0.023
microtubule cytoskeleton organization GO:0000226 176 0.023
cellular protein catabolic process GO:0044257 261 0.023
cellular response to cytokine stimulus GO:0071345 181 0.023
Human
sex determination GO:0007530 3 0.023
cerebral cortex cell migration GO:0021795 3 0.023
regulation of secretion by cell GO:1903530 177 0.023
Human
peptidyl lysine modification GO:0018205 144 0.023
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
embryonic epithelial tube formation GO:0001838 4 0.023
regionalization GO:0003002 29 0.023
Zebrafish Mouse
myoblast fusion GO:0007520 1 0.023
regulation of epithelial to mesenchymal transition GO:0010717 37 0.023
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
lipid metabolic process GO:0006629 381 0.022
single organism nuclear import GO:1902593 104 0.022
regulation of neuron differentiation GO:0045664 70 0.022
neural crest cell development GO:0014032 3 0.022
regulation of cell activation GO:0050865 125 0.022
response to other organism GO:0051707 261 0.022
histone modification GO:0016570 251 0.022
Human
heart morphogenesis GO:0003007 48 0.022
peptidyl tyrosine phosphorylation GO:0018108 170 0.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.022
positive regulation of cellular component biogenesis GO:0044089 158 0.022
myeloid cell differentiation GO:0030099 117 0.021
Human
cellular macromolecular complex assembly GO:0034622 324 0.021
positive regulation of protein transport GO:0051222 135 0.021
Human
lung alveolus development GO:0048286 4 0.021
negative regulation of locomotion GO:0040013 118 0.021
positive regulation of cell cycle GO:0045787 140 0.021
Human
reactive oxygen species metabolic process GO:0072593 75 0.021
regulation of vasculature development GO:1901342 97 0.021
neuron projection morphogenesis GO:0048812 50 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.021
negative regulation of protein processing GO:0010955 142 0.021
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.021
Human
microtubule based process GO:0007017 210 0.021
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.021
oocyte development GO:0048599 1 0.021
lymphocyte activation GO:0046649 133 0.021
regulation of protein localization to nucleus GO:1900180 85 0.021
response to organic cyclic compound GO:0014070 204 0.021
Human
peptidyl lysine acetylation GO:0018394 101 0.021
Human
regulation of intracellular transport GO:0032386 195 0.021
Human
cell division GO:0051301 168 0.021
salivary gland morphogenesis GO:0007435 4 0.020
oocyte differentiation GO:0009994 2 0.020
regulation of neuron projection development GO:0010975 57 0.020
immune response GO:0006955 307 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.020
axon regeneration GO:0031103 1 0.020
camp metabolic process GO:0046058 61 0.020
single organism reproductive process GO:0044702 98 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
positive regulation of chemotaxis GO:0050921 57 0.020
nucleoside phosphate biosynthetic process GO:1901293 109 0.020
cell migration involved in gastrulation GO:0042074 1 0.020
stem cell division GO:0017145 2 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.020
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.020
forebrain neuron differentiation GO:0021879 3 0.020
bmp signaling pathway GO:0030509 49 0.020
regulation of map kinase activity GO:0043405 108 0.020
developmental programmed cell death GO:0010623 3 0.020
compound eye development GO:0048749 1 0.020
negative regulation of cellular component movement GO:0051271 106 0.020
endothelial cell migration GO:0043542 86 0.019
endochondral bone morphogenesis GO:0060350 3 0.019
specification of organ identity GO:0010092 3 0.019
response to nitrogen compound GO:1901698 184 0.019
regulation of ion transport GO:0043269 189 0.019
positive regulation of endopeptidase activity GO:0010950 84 0.019
negative regulation of protein maturation GO:1903318 142 0.019
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.019
regulation of ectoderm development GO:2000383 1 0.019
cellular response to organic cyclic compound GO:0071407 127 0.019
Human
metencephalon development GO:0022037 2 0.019
eye development GO:0001654 42 0.019
Zebrafish
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.019
regulation of hormone levels GO:0010817 125 0.019
Human
forebrain development GO:0030900 26 0.018
Zebrafish
negative regulation of sodium dependent phosphate transport GO:2000119 1 0.018
regulation of behavior GO:0050795 82 0.018
innate immune response GO:0045087 178 0.018
regulation of osteoblast differentiation GO:0045667 38 0.018
response to external biotic stimulus GO:0043207 261 0.018
establishment of planar polarity GO:0001736 3 0.018
negative regulation of protein transport GO:0051224 75 0.018
regulation of protein maturation GO:1903317 150 0.018
Human
membrane organization GO:0061024 292 0.018
nephron development GO:0072006 30 0.018
skin development GO:0043588 76 0.018
Mouse
negative regulation of kidney development GO:0090185 2 0.018
mitotic nuclear division GO:0007067 119 0.018
positive regulation of map kinase activity GO:0043406 80 0.018
t cell differentiation in thymus GO:0033077 4 0.018
cellular lipid metabolic process GO:0044255 303 0.018
neural tube patterning GO:0021532 2 0.018
Zebrafish
somitogenesis GO:0001756 2 0.018
nitrogen compound transport GO:0071705 191 0.018
Human
regulation of cell proliferation involved in kidney development GO:1901722 3 0.018
protein modification by small protein conjugation GO:0032446 342 0.018
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.018
cellular response to external stimulus GO:0071496 111 0.018
tube closure GO:0060606 3 0.017
tripartite regional subdivision GO:0007351 2 0.017
Mouse
camp biosynthetic process GO:0006171 47 0.017
establishment of tissue polarity GO:0007164 3 0.017
response to radiation GO:0009314 151 0.017
neural tube closure GO:0001843 3 0.017
regulation of response to wounding GO:1903034 101 0.017
regulation of chemotaxis GO:0050920 74 0.017
glomerulus development GO:0032835 15 0.017
organelle fission GO:0048285 149 0.017
mesenchymal cell differentiation GO:0048762 52 0.017
Human

TCF7L1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.055
nervous system disease DOID:863 431 0.055
eye and adnexa disease DOID:1492 150 0.050
eye disease DOID:5614 149 0.040
disease of metabolism DOID:0014667 295 0.027
Human
retinal disease DOID:5679 118 0.018
musculoskeletal system disease DOID:17 223 0.018
connective tissue disease DOID:65 109 0.018
inherited metabolic disorder DOID:655 242 0.018