Homo sapiens

0 known processes

GBF1

golgi brefeldin A resistant guanine nucleotide exchange factor 1

(Aliases: FLJ21263,KIAA0248,MGC134878,MGC134877,ARF1GEF,FLJ21500)

GBF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 78 0.336
cytoplasmic transport GO:0016482 379 0.261
nucleoside catabolic process GO:0009164 408 0.247
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.179
Fly
guanosine containing compound catabolic process GO:1901069 239 0.142
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.142
Fly
vesicle mediated transport GO:0016192 371 0.140
Fly
purine containing compound catabolic process GO:0072523 411 0.123
Fly
nucleotide catabolic process GO:0009166 408 0.120
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.117
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.116
Fly
ras protein signal transduction GO:0007265 73 0.116
nucleoside triphosphate metabolic process GO:0009141 422 0.116
Fly
regulation of ras protein signal transduction GO:0046578 155 0.115
Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.106
Fly
lipid metabolic process GO:0006629 381 0.106
purine ribonucleotide catabolic process GO:0009154 404 0.104
Fly
segmentation GO:0035282 4 0.097
organophosphate catabolic process GO:0046434 430 0.094
Fly
positive regulation of gtpase activity GO:0043547 166 0.091
Fly
ribonucleoside triphosphate metabolic process GO:0009199 412 0.088
Fly
single organism cellular localization GO:1902580 332 0.088
glycerolipid metabolic process GO:0046486 107 0.085
regulation of nucleoside metabolic process GO:0009118 209 0.079
Fly
lipid biosynthetic process GO:0008610 177 0.077
ribonucleoside catabolic process GO:0042454 406 0.077
Fly
positive regulation of rab gtpase activity GO:0032851 39 0.076
purine nucleoside catabolic process GO:0006152 398 0.075
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.075
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.075
Fly
regulation of rab protein signal transduction GO:0032483 39 0.074
secretion GO:0046903 254 0.074
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.072
Fly
positive regulation of catabolic process GO:0009896 310 0.072
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.071
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.071
Fly
regulation of cell differentiation GO:0045595 393 0.071
positive regulation of nucleoside metabolic process GO:0045979 186 0.070
Fly
intracellular protein transport GO:0006886 270 0.069
positive regulation of gtp catabolic process GO:0033126 166 0.069
Fly
gtp metabolic process GO:0046039 239 0.067
Fly
golgi vesicle transport GO:0048193 80 0.067
regulation of gtp catabolic process GO:0033124 180 0.064
Fly
regulation of purine nucleotide metabolic process GO:1900542 264 0.063
Fly
nucleocytoplasmic transport GO:0006913 176 0.063
regulation of intracellular transport GO:0032386 195 0.062
guanosine containing compound metabolic process GO:1901068 244 0.061
Fly
glycosyl compound catabolic process GO:1901658 413 0.059
Fly
gtp catabolic process GO:0006184 237 0.057
Fly
ribonucleotide catabolic process GO:0009261 405 0.056
Fly
cell morphogenesis GO:0000902 296 0.055
Fly
cellular lipid metabolic process GO:0044255 303 0.055
rab protein signal transduction GO:0032482 4 0.052
regulation of gtpase activity GO:0043087 180 0.051
Fly
regulation of nucleotide metabolic process GO:0006140 269 0.048
Fly
neuromuscular junction development GO:0007528 3 0.047
negative regulation of cellular component organization GO:0051129 235 0.047
regulation of small gtpase mediated signal transduction GO:0051056 156 0.047
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.046
Fly
rho protein signal transduction GO:0007266 26 0.046
chromatin organization GO:0006325 351 0.046
regulation of cellular component biogenesis GO:0044087 281 0.046
cell development GO:0048468 328 0.045
Fly
nitrogen compound transport GO:0071705 191 0.045
positive regulation of nucleotide metabolic process GO:0045981 230 0.045
Fly
rna processing GO:0006396 255 0.044
positive regulation of nucleotide catabolic process GO:0030813 185 0.044
Fly
somitogenesis GO:0001756 2 0.043
regulation of dna metabolic process GO:0051052 153 0.043
positive regulation of ras gtpase activity GO:0032320 117 0.041
mrna metabolic process GO:0016071 175 0.039
regulation of nucleotide catabolic process GO:0030811 205 0.039
Fly
regulation of triglyceride catabolic process GO:0010896 6 0.038
neutral lipid catabolic process GO:0046461 12 0.037
regulation of cell development GO:0060284 161 0.037
regulation of rab gtpase activity GO:0032313 39 0.037
purine ribonucleoside metabolic process GO:0046128 437 0.036
Fly
regulation of cell cycle GO:0051726 393 0.035
rna splicing GO:0008380 131 0.035
regulation of cellular ketone metabolic process GO:0010565 50 0.034
nervous system development GO:0007399 293 0.034
locomotory behavior GO:0007626 1 0.034
wnt signaling pathway GO:0016055 156 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.033
determination of adult lifespan GO:0008340 2 0.033
cellular protein catabolic process GO:0044257 261 0.033
nuclear transport GO:0051169 179 0.033
maintenance of location GO:0051235 112 0.033
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
peptide transport GO:0015833 74 0.032
cellular macromolecule catabolic process GO:0044265 380 0.031
regulation of secretion by cell GO:1903530 177 0.031
microtubule based process GO:0007017 210 0.031
photoreceptor cell differentiation GO:0046530 2 0.030
female gamete generation GO:0007292 2 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
oocyte differentiation GO:0009994 2 0.030
regulation of establishment of protein localization GO:0070201 242 0.030
multicellular organismal aging GO:0010259 3 0.030
protein processing GO:0016485 226 0.030
negative regulation of developmental process GO:0051093 247 0.029
actin filament based process GO:0030029 224 0.029
regulation of cell morphogenesis GO:0022604 153 0.028
cell substrate adhesion GO:0031589 132 0.028
protein maturation GO:0051604 233 0.028
protein targeting GO:0006605 187 0.028
morphogenesis of embryonic epithelium GO:0016331 4 0.028
regulation of protein localization GO:0032880 296 0.028
biological adhesion GO:0022610 331 0.027
cellular amino acid metabolic process GO:0006520 116 0.027
vesicle organization GO:0016050 62 0.027
protein catabolic process GO:0030163 325 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
neuron projection development GO:0031175 106 0.027
oocyte development GO:0048599 1 0.027
regulation of secretion GO:0051046 194 0.027
nerve development GO:0021675 4 0.026
cell morphogenesis involved in differentiation GO:0000904 144 0.026
positive regulation of developmental process GO:0051094 314 0.025
post embryonic development GO:0009791 2 0.025
cellular component morphogenesis GO:0032989 314 0.025
Fly
organophosphate biosynthetic process GO:0090407 163 0.025
regulation of ras gtpase activity GO:0032318 128 0.024
Fly
purine nucleotide catabolic process GO:0006195 405 0.024
Fly
regulation of cell motility GO:2000145 299 0.024
regulation of protein transport GO:0051223 213 0.024
memory GO:0007613 3 0.024
regulation of cell adhesion GO:0030155 166 0.024
peripheral nervous system development GO:0007422 2 0.024
chromatin modification GO:0016568 298 0.024
glycerolipid biosynthetic process GO:0045017 51 0.024
cell part morphogenesis GO:0032990 137 0.024
covalent chromatin modification GO:0016569 254 0.024
triglyceride catabolic process GO:0019433 10 0.024
cell projection organization GO:0030030 252 0.024
cell projection morphogenesis GO:0048858 129 0.024
amine metabolic process GO:0009308 44 0.024
associative learning GO:0008306 1 0.023
system process GO:0003008 349 0.023
negative regulation of multicellular organismal process GO:0051241 317 0.023
purine nucleoside monophosphate metabolic process GO:0009126 186 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
neuron differentiation GO:0030182 138 0.023
macromolecule methylation GO:0043414 97 0.023
protein ubiquitination GO:0016567 314 0.022
histone modification GO:0016570 251 0.022
proteasomal protein catabolic process GO:0010498 176 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
neurogenesis GO:0022008 169 0.022
regulation of kinase activity GO:0043549 314 0.022
canonical wnt signaling pathway GO:0060070 116 0.022
regulation of growth GO:0040008 165 0.021
long term memory GO:0007616 2 0.021
negative regulation of protein modification process GO:0031400 200 0.021
nucleobase containing compound transport GO:0015931 51 0.021
single organism membrane organization GO:0044802 268 0.021
regulation of lipid metabolic process GO:0019216 96 0.021
regulation of cytoplasmic transport GO:1903649 149 0.020
nuclear export GO:0051168 69 0.020
apoptotic signaling pathway GO:0097190 268 0.020
positive regulation of transport GO:0051050 336 0.020
nucleoside monophosphate metabolic process GO:0009123 191 0.020
lipid catabolic process GO:0016042 84 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
ribonucleoside monophosphate catabolic process GO:0009158 158 0.020
anterograde axon cargo transport GO:0008089 1 0.020
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.020
Fly
generation of neurons GO:0048699 152 0.020
cellular ketone metabolic process GO:0042180 80 0.020
atp metabolic process GO:0046034 176 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
neurological system process GO:0050877 163 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
glycerolipid catabolic process GO:0046503 18 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
immune response GO:0006955 307 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.019
negative regulation of organelle organization GO:0010639 126 0.019
ribonucleoside monophosphate metabolic process GO:0009161 187 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
Fly
rna transport GO:0050658 39 0.019
regulation of cellular component movement GO:0051270 334 0.019
cellular protein complex assembly GO:0043623 188 0.019
cell adhesion GO:0007155 325 0.019
microtubule cytoskeleton organization GO:0000226 176 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
membrane organization GO:0061024 292 0.018
organ formation GO:0048645 3 0.018
regulation of transferase activity GO:0051338 355 0.018
response to oxygen containing compound GO:1901700 369 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
heart development GO:0007507 95 0.018
protein secretion GO:0009306 98 0.018
Fly
rna localization GO:0006403 41 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
axon cargo transport GO:0008088 2 0.018
er to golgi vesicle mediated transport GO:0006888 19 0.017
cellular lipid catabolic process GO:0044242 65 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
positive regulation of protein transport GO:0051222 135 0.017
response to abiotic stimulus GO:0009628 336 0.017
hormone transport GO:0009914 68 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
lymphocyte activation GO:0046649 133 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
blastoderm segmentation GO:0007350 2 0.017
cardiovascular system development GO:0072358 262 0.017
regulation of nervous system development GO:0051960 88 0.017
cell cell signaling GO:0007267 155 0.017
response to other organism GO:0051707 261 0.017
spermatid development GO:0007286 4 0.017
cell fate determination GO:0001709 3 0.017
intracellular mrna localization GO:0008298 1 0.017
single organism nuclear import GO:1902593 104 0.017
regulation of proteolysis GO:0030162 293 0.017
mrna processing GO:0006397 133 0.017
regulation of cellular response to stress GO:0080135 244 0.017
retrograde transport endosome to golgi GO:0042147 45 0.017
negative regulation of cell death GO:0060548 345 0.016
negative regulation of wnt signaling pathway GO:0030178 69 0.016
growth GO:0040007 202 0.016
positive regulation of response to external stimulus GO:0032103 88 0.016
taxis GO:0042330 157 0.016
endomembrane system organization GO:0010256 196 0.016
Fly
mitotic cell cycle GO:0000278 326 0.016
oogenesis GO:0048477 2 0.016
positive regulation of intracellular transport GO:0032388 104 0.016
isotype switching GO:0045190 3 0.016
positive regulation of transferase activity GO:0051347 227 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
protein localization to membrane GO:0072657 160 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
mitotic cell cycle process GO:1903047 286 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
lipid localization GO:0010876 106 0.015
epithelium development GO:0060429 227 0.015
Fly
protein localization to organelle GO:0033365 280 0.015
cellular amine metabolic process GO:0044106 41 0.015
autophagy GO:0006914 88 0.015
cell matrix adhesion GO:0007160 85 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
endosomal transport GO:0016197 129 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
neural tube formation GO:0001841 3 0.015
limbic system development GO:0021761 3 0.015
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
synaptic vesicle endocytosis GO:0048488 2 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
adult locomotory behavior GO:0008344 1 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.015
regulation of peptide transport GO:0090087 62 0.015
regulation of feeding behavior GO:0060259 3 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
tube development GO:0035295 125 0.014
Fly
cell activation GO:0001775 213 0.014
regulation of immunoglobulin production GO:0002637 4 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
neurotransmitter secretion GO:0007269 4 0.014
central nervous system development GO:0007417 123 0.014
regulation of chromosome organization GO:0033044 103 0.014
rhythmic behavior GO:0007622 2 0.014
secretion by cell GO:0032940 226 0.014
Fly
oxidation reduction process GO:0055114 396 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
signal release GO:0023061 70 0.014
cytokine production GO:0001816 247 0.014
regulation of hormone levels GO:0010817 125 0.014
mrna splicing via spliceosome GO:0000398 89 0.014
regulation of cell projection organization GO:0031344 107 0.014
cellular chemical homeostasis GO:0055082 180 0.014
protein import GO:0017038 130 0.014
single organism cell adhesion GO:0098602 179 0.014
protein alkylation GO:0008213 74 0.014
regulation of muscle cell differentiation GO:0051147 31 0.014
inner ear morphogenesis GO:0042472 4 0.013
actin cytoskeleton organization GO:0030036 207 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
dephosphorylation GO:0016311 209 0.013
response to hormone GO:0009725 175 0.013
transmembrane transport GO:0055085 399 0.013
cranial nerve development GO:0021545 4 0.013
hormone secretion GO:0046879 65 0.013
rna interference GO:0016246 4 0.013
protein import into nucleus GO:0006606 104 0.013
establishment of rna localization GO:0051236 39 0.013
cell growth GO:0016049 160 0.013
regulation of cytokine production GO:0001817 232 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
circulatory system development GO:0072359 262 0.013
spermatid differentiation GO:0048515 4 0.013
phospholipid metabolic process GO:0006644 99 0.013
peptide hormone secretion GO:0030072 50 0.013
circadian behavior GO:0048512 2 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
reactive oxygen species biosynthetic process GO:1903409 4 0.013
inorganic ion transmembrane transport GO:0098660 231 0.013
negative regulation of cell differentiation GO:0045596 171 0.013
regulation of protein catabolic process GO:0042176 155 0.013
negative regulation of cell development GO:0010721 48 0.013
response to extracellular stimulus GO:0009991 85 0.013
positive regulation of cell differentiation GO:0045597 211 0.013
sodium ion transmembrane transport GO:0035725 59 0.013
phosphatidic acid biosynthetic process GO:0006654 4 0.013
cell division GO:0051301 168 0.013
neural tube closure GO:0001843 3 0.013
regulation of peptide hormone secretion GO:0090276 41 0.013
growth hormone secretion GO:0030252 4 0.012
phospholipid biosynthetic process GO:0008654 44 0.012
mating GO:0007618 1 0.012
mesenchymal cell development GO:0014031 50 0.012
regulation of rho protein signal transduction GO:0035023 79 0.012
methylation GO:0032259 106 0.012
positive regulation of dna templated transcription elongation GO:0032786 18 0.012
pancreatic juice secretion GO:0030157 4 0.012
stem cell differentiation GO:0048863 93 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
atp catabolic process GO:0006200 157 0.012
reproductive process GO:0022414 106 0.012
positive regulation of proteolysis GO:0045862 142 0.012
regulation of protein processing GO:0070613 150 0.012
chemical homeostasis GO:0048878 306 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
ribonucleoprotein complex biogenesis GO:0022613 116 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
negative regulation of protein processing GO:0010955 142 0.012
neuron development GO:0048666 113 0.012
regulation of neuron differentiation GO:0045664 70 0.012
tube closure GO:0060606 3 0.012
protein localization to plasma membrane GO:0072659 93 0.012
somatic muscle development GO:0007525 1 0.012
positive regulation of locomotion GO:0040017 186 0.012
microtubule based movement GO:0007018 32 0.012
anterior posterior axis specification GO:0009948 2 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
regulation of immune response GO:0050776 201 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
leukocyte activation GO:0045321 164 0.012
regulation of dna templated transcription elongation GO:0032784 23 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
activation of protein kinase activity GO:0032147 90 0.011
negative regulation of proteolysis GO:0045861 132 0.011
histone methylation GO:0016571 60 0.011
dna recombination GO:0006310 77 0.011
single organism reproductive process GO:0044702 98 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
nuclear migration GO:0007097 1 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
regulation of lipid catabolic process GO:0050994 23 0.011
dna repair GO:0006281 198 0.011
establishment of planar polarity GO:0001736 3 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
sleep GO:0030431 2 0.011
metencephalon development GO:0022037 2 0.011
primary neural tube formation GO:0014020 3 0.011
regulation of protein kinase activity GO:0045859 289 0.011
somatic stem cell maintenance GO:0035019 4 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
cell projection assembly GO:0030031 126 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
organelle localization GO:0051640 84 0.011
mapk cascade GO:0000165 288 0.011
positive regulation of immune system process GO:0002684 283 0.011
peptide secretion GO:0002790 51 0.011
regeneration GO:0031099 4 0.011
protein polyubiquitination GO:0000209 110 0.011
negative regulation of growth GO:0045926 97 0.011
mrna transport GO:0051028 30 0.011
response to lipid GO:0033993 206 0.011
axis elongation GO:0003401 4 0.011
positive regulation of rho gtpase activity GO:0032321 56 0.011
receptor mediated endocytosis GO:0006898 84 0.011
acylglycerol metabolic process GO:0006639 27 0.011
plasma membrane organization GO:0007009 115 0.011
negative regulation of cell migration GO:0030336 102 0.011
positive regulation of autophagy GO:0010508 24 0.011
nucleic acid transport GO:0050657 39 0.011
protein localization to nucleus GO:0034504 136 0.011
rna export from nucleus GO:0006405 33 0.010
response to biotic stimulus GO:0009607 276 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
negative regulation of cellular catabolic process GO:0031330 83 0.010
protein targeting to nucleus GO:0044744 104 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
regulation of protein secretion GO:0050708 86 0.010
metal ion transport GO:0030001 272 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.010
negative regulation of cellular component movement GO:0051271 106 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
response to external biotic stimulus GO:0043207 261 0.010
neuroblast proliferation GO:0007405 4 0.010
b cell activation GO:0042113 33 0.010
central nervous system neuron axonogenesis GO:0021955 3 0.010
negative regulation of locomotion GO:0040013 118 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
negative regulation of protein maturation GO:1903318 142 0.010
negative regulation of phosphate metabolic process GO:0045936 267 0.010
rna splicing via transesterification reactions GO:0000375 90 0.010

GBF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.024
disease of cellular proliferation DOID:14566 174 0.024
organ system cancer DOID:0050686 164 0.024
musculoskeletal system disease DOID:17 223 0.021
epilepsy syndrome DOID:1826 41 0.016
central nervous system disease DOID:331 186 0.016
brain disease DOID:936 73 0.016
nervous system disease DOID:863 431 0.016
disease of metabolism DOID:0014667 295 0.014
sensory system disease DOID:0050155 203 0.014
disease of mental health DOID:150 70 0.013
electroclinical syndrome DOID:0050701 32 0.012
neonatal period electroclinical syndrome DOID:0050702 19 0.012
immune system disease DOID:2914 155 0.010