|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.994
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.977
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.945
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.864
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.861
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.836
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.812
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.789
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.766
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.731
|
|
|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.710
|
|
|
|
growth
|
GO:0040007 |
202 |
0.699
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.698
|
|
|
|
response to host defenses
|
GO:0052200 |
2 |
0.674
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.671
|
Mouse |
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.663
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.659
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.640
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.633
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.622
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.609
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.593
|
Human |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.581
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.544
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.542
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.535
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.532
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.531
|
|
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.513
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.511
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.511
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.508
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.505
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.502
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.501
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.490
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.490
|
|
|
|
ventral spinal cord interneuron differentiation
|
GO:0021514 |
1 |
0.480
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.454
|
Mouse |
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.448
|
Mouse |
|
|
anatomical structure regression
|
GO:0060033 |
1 |
0.444
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.443
|
|
|
|
heart valve formation
|
GO:0003188 |
2 |
0.437
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.431
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.429
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.429
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.420
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.416
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.403
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.403
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.399
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.394
|
Zebrafish Mouse |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.392
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.388
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.385
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.385
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.374
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.366
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.366
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.364
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.363
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.363
|
Mouse |
|
|
protein acetylation
|
GO:0006473 |
116 |
0.353
|
|
|
|
atrioventricular valve formation
|
GO:0003190 |
1 |
0.352
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.352
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.347
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.343
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.342
|
Mouse |
|
|
negative regulation of chromatin silencing at rdna
|
GO:0061188 |
2 |
0.338
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.328
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.326
|
Mouse |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.324
|
Zebrafish |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.310
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.302
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.301
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.296
|
Zebrafish Mouse |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.292
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.292
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.290
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.289
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.285
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.283
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.278
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.278
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.278
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.277
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.275
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.267
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.267
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.264
|
Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.263
|
Zebrafish Mouse |
|
|
brain development
|
GO:0007420 |
97 |
0.260
|
Mouse |
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.259
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.257
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.253
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.251
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.249
|
Mouse |
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.245
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.244
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.243
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.241
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.236
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.234
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.232
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.231
|
Zebrafish |
|
|
positive regulation of chondrocyte differentiation
|
GO:0032332 |
4 |
0.229
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.229
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.228
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.228
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.227
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.226
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.225
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.225
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.219
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.218
|
|
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
1 |
0.217
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.217
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.217
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.216
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.216
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.215
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.209
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.208
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.207
|
|
|
|
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900224 |
1 |
0.200
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.197
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.194
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.186
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.186
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.181
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.180
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.180
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.178
|
Zebrafish |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.176
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.175
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.175
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.174
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.173
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
2 |
0.172
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.166
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.162
|
|
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
1 |
0.161
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.160
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.160
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.159
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.159
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.158
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.157
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.156
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.153
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.152
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.151
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.149
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.148
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.147
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.144
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.143
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.143
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.142
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.140
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.139
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.139
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.139
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.138
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.137
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.135
|
Zebrafish Mouse |
|
|
cerebellar cortex development
|
GO:0021695 |
1 |
0.135
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.134
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.134
|
Zebrafish Mouse |
|
|
blastocyst development
|
GO:0001824 |
3 |
0.133
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.132
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.132
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.132
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.132
|
Zebrafish |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.132
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.132
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.131
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.130
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.130
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.130
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.130
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.129
|
|
|
|
sebaceous gland development
|
GO:0048733 |
1 |
0.129
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.128
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.127
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.126
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.126
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.126
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.125
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.124
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.123
|
|
|
|
evasion or tolerance of host defenses by virus
|
GO:0019049 |
2 |
0.122
|
|
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.121
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.120
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.120
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.120
|
Zebrafish Mouse |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.118
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.117
|
|
|
|
negative regulation of schwann cell proliferation
|
GO:0010626 |
1 |
0.115
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.115
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.115
|
|
|
|
evasion or tolerance of host defenses
|
GO:0044415 |
2 |
0.115
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.115
|
Zebrafish |
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.114
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.113
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.112
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.112
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.112
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.112
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.111
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.111
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.111
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.111
|
Human |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.110
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.110
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.110
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.109
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.109
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.109
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.108
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.108
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.108
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.108
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.107
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.107
|
Mouse |
|
|
response to host
|
GO:0075136 |
2 |
0.107
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.106
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.105
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.105
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.103
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.103
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.103
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.102
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.101
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.101
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.100
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.100
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.100
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.100
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.098
|
|
|
|
ribonucleoprotein complex export from nucleus
|
GO:0071426 |
4 |
0.098
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.098
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.098
|
Human |
|
|
mesonephros development
|
GO:0001823 |
17 |
0.097
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.095
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.095
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.095
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.095
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.094
|
Zebrafish |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.094
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.094
|
|
|
|
regulation of glycolytic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072361 |
2 |
0.093
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.093
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.093
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.093
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.092
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.091
|
|
|
|
tongue development
|
GO:0043586 |
1 |
0.091
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.091
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.090
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.090
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.090
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.090
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.089
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.089
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.088
|
|
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
0.088
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.088
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.087
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.087
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.087
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.086
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.086
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.085
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.085
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.084
|
|
|
|
regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900175 |
1 |
0.084
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.084
|
|
|
|
osteoblast development
|
GO:0002076 |
2 |
0.084
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.083
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.083
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.083
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.082
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.082
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.082
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.082
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.082
|
|
|
|
regulation of nodal signaling pathway involved in determination of left right asymmetry
|
GO:1900145 |
1 |
0.082
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.081
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.081
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
18 |
0.081
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.080
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.080
|
|
|
|
protein heterotrimerization
|
GO:0070208 |
4 |
0.080
|
Human |
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.079
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.079
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.078
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.078
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.078
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.078
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.078
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.078
|
|
|
|
thalamus development
|
GO:0021794 |
2 |
0.078
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.078
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.077
|
|
|
|
erythrocyte development
|
GO:0048821 |
3 |
0.077
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.077
|
|
|
|
system process
|
GO:0003008 |
349 |
0.076
|
Zebrafish Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.076
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.075
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.075
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.075
|
|
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.075
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.074
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.074
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
1 |
0.074
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.074
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.073
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.073
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.073
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.073
|
Zebrafish |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.073
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.072
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.072
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.072
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
9 |
0.072
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
1 |
0.072
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.072
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.071
|
Human |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.071
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.071
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.071
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.071
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.070
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.070
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.070
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.070
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.070
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.069
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.069
|
Mouse |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.069
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.069
|
|
|
|
interaction with symbiont
|
GO:0051702 |
26 |
0.069
|
|
|
|
hard palate development
|
GO:0060022 |
1 |
0.068
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.068
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.067
|
|
|
|
sensory perception of light stimulus
|
GO:0050953 |
35 |
0.066
|
|
|
|
regulation of nodal signaling pathway
|
GO:1900107 |
1 |
0.066
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.066
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.066
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.066
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.066
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.066
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.065
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.065
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.064
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.064
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.064
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.064
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.064
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.063
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.063
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.063
|
|
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.062
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.062
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.062
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.062
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.062
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.062
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.061
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.061
|
Human |
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.061
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.061
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.061
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
3 |
0.061
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.060
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.060
|
|
|
|
regulation of chromatin silencing at rdna
|
GO:0061187 |
2 |
0.060
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.060
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.059
|
Human |
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.059
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.059
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.059
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.059
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.059
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.059
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.058
|
Human |
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.058
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.057
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.057
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.057
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.057
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.057
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.057
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.056
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.056
|
Zebrafish Mouse |
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.056
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.055
|
|
|
|
evasion or tolerance of defenses of other organism involved in symbiotic interaction
|
GO:0051834 |
2 |
0.055
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.054
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.054
|
Mouse |
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.054
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.054
|
Mouse |
|
|
convergent extension
|
GO:0060026 |
1 |
0.054
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.054
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.054
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.054
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.053
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.053
|
|
|
|
mhc class ii biosynthetic process
|
GO:0045342 |
4 |
0.053
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.053
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.053
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.053
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.053
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.053
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.052
|
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.052
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.052
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.052
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.052
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.052
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.051
|
|
|
|
cell differentiation in hindbrain
|
GO:0021533 |
1 |
0.051
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.051
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.050
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.050
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.050
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.050
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.050
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.050
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.050
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.050
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.049
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.049
|
Mouse |
|
|
startle response
|
GO:0001964 |
3 |
0.049
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.049
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.049
|
|
|
|
avoidance of defenses of other organism involved in symbiotic interaction
|
GO:0051832 |
2 |
0.049
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.049
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.048
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.048
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.048
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.048
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.048
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.048
|
Zebrafish |
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.048
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.048
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.047
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.047
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.047
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.047
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.047
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.047
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.046
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.046
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.046
|
Mouse |
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.046
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.046
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.046
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.046
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.046
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.046
|
Human |
|
|
response to fungus
|
GO:0009620 |
4 |
0.046
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.046
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.046
|
|
|
|
head development
|
GO:0060322 |
108 |
0.046
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.046
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.045
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.045
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.045
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.045
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.045
|
Human |
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.045
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.045
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.044
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.044
|
|
|
|
regulation of transforming growth factor beta production
|
GO:0071634 |
13 |
0.044
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.044
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.044
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.044
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
1 |
0.044
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.043
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.043
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.043
|
|
