Homo sapiens

11 known processes

UCHL3

ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)

(Aliases: UCH-L3)

UCHL3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.784
positive regulation of catabolic process GO:0009896 310 0.165
endocytosis GO:0006897 159 0.146
modification dependent protein catabolic process GO:0019941 209 0.138
ubiquitin dependent protein catabolic process GO:0006511 206 0.135
protein catabolic process GO:0030163 325 0.130
vesicle mediated transport GO:0016192 371 0.129
modification dependent macromolecule catabolic process GO:0043632 212 0.117
embryo development GO:0009790 123 0.106
nervous system development GO:0007399 293 0.097
cellular macromolecule catabolic process GO:0044265 380 0.094
oogenesis GO:0048477 2 0.089
female gamete generation GO:0007292 2 0.083
amine metabolic process GO:0009308 44 0.082
cell development GO:0048468 328 0.082
regulation of protein transport GO:0051223 213 0.076
multicellular organismal aging GO:0010259 3 0.071
regulation of mitotic cell cycle GO:0007346 189 0.069
cellular amine metabolic process GO:0044106 41 0.063
protein modification by small protein removal GO:0070646 92 0.062
purine nucleoside triphosphate metabolic process GO:0009144 412 0.061
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.061
determination of adult lifespan GO:0008340 2 0.060
cellular protein catabolic process GO:0044257 261 0.059
positive regulation of cellular catabolic process GO:0031331 284 0.056
purine ribonucleoside metabolic process GO:0046128 437 0.055
negative regulation of programmed cell death GO:0043069 321 0.055
cellular amino acid metabolic process GO:0006520 116 0.054
neuron differentiation GO:0030182 138 0.054
guanosine containing compound catabolic process GO:1901069 239 0.053
intracellular protein transport GO:0006886 270 0.049
posttranscriptional regulation of gene expression GO:0010608 213 0.048
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.047
regulation of cell cycle phase transition GO:1901987 126 0.046
purine nucleoside catabolic process GO:0006152 398 0.044
cellular response to dna damage stimulus GO:0006974 379 0.042
positive regulation of programmed cell death GO:0043068 249 0.042
guanosine containing compound metabolic process GO:1901068 244 0.042
protein localization to organelle GO:0033365 280 0.042
cell cycle checkpoint GO:0000075 117 0.041
regulation of cell cycle GO:0051726 393 0.041
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.041
receptor mediated endocytosis GO:0006898 84 0.040
positive regulation of proteolysis GO:0045862 142 0.040
regulation of protein catabolic process GO:0042176 155 0.040
negative regulation of cell death GO:0060548 345 0.040
mitotic cell cycle GO:0000278 326 0.038
negative regulation of apoptotic process GO:0043066 316 0.038
cytokine production GO:0001816 247 0.037
neurogenesis GO:0022008 169 0.036
actin filament based process GO:0030029 224 0.035
positive regulation of cell proliferation GO:0008284 301 0.035
epithelium development GO:0060429 227 0.035
regulation of cellular response to stress GO:0080135 244 0.035
innate immune response GO:0045087 178 0.035
apoptotic mitochondrial changes GO:0008637 57 0.034
regulation of protein stability GO:0031647 87 0.033
system process GO:0003008 349 0.033
purine containing compound catabolic process GO:0072523 411 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.031
gtp metabolic process GO:0046039 239 0.031
positive regulation of hydrolase activity GO:0051345 331 0.031
single organism cellular localization GO:1902580 332 0.031
mitotic cell cycle phase transition GO:0044772 162 0.030
organophosphate catabolic process GO:0046434 430 0.030
establishment of protein localization to organelle GO:0072594 172 0.029
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
positive regulation of protein catabolic process GO:0045732 75 0.029
nucleotide catabolic process GO:0009166 408 0.029
neural crest cell development GO:0014032 3 0.028
purine nucleotide catabolic process GO:0006195 405 0.028
response to abiotic stimulus GO:0009628 336 0.028
apoptotic signaling pathway GO:0097190 268 0.028
metal ion homeostasis GO:0055065 169 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
regulation of proteolysis GO:0030162 293 0.027
purine containing compound salvage GO:0043101 2 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.026
generation of neurons GO:0048699 152 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.026
protein k63 linked deubiquitination GO:0070536 21 0.026
reproduction GO:0000003 63 0.025
negative regulation of cell cycle phase transition GO:1901988 89 0.025
regulation of proteasomal protein catabolic process GO:0061136 87 0.025
oocyte differentiation GO:0009994 2 0.025
positive regulation of transport GO:0051050 336 0.025
gtp catabolic process GO:0006184 237 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
regulation of protein import into nucleus GO:0042306 78 0.025
purine nucleotide biosynthetic process GO:0006164 84 0.025
organelle fission GO:0048285 149 0.024
chemical homeostasis GO:0048878 306 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
protein import GO:0017038 130 0.023
regulation of cytoplasmic transport GO:1903649 149 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
cell division GO:0051301 168 0.023
protein targeting GO:0006605 187 0.023
protein deubiquitination GO:0016579 79 0.022
regulation of protein targeting GO:1903533 91 0.022
regulation of response to dna damage stimulus GO:2001020 94 0.022
regulation of intracellular protein transport GO:0033157 123 0.022
response to other organism GO:0051707 261 0.022
oxidation reduction process GO:0055114 396 0.022
immune response GO:0006955 307 0.022
regulation of mitotic cell cycle phase transition GO:1901990 118 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
mitotic cell cycle process GO:1903047 286 0.022
mitochondrial transport GO:0006839 60 0.022
rna interference GO:0016246 4 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
secretion by cell GO:0032940 226 0.021
protein import into mitochondrial matrix GO:0030150 1 0.021
calcium ion transport GO:0006816 147 0.021
cell type specific apoptotic process GO:0097285 125 0.021
positive regulation of cell death GO:0010942 263 0.021
segmentation GO:0035282 4 0.021
cellular ketone metabolic process GO:0042180 80 0.020
positive regulation of protein transport GO:0051222 135 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
transmembrane transport GO:0055085 399 0.020
central nervous system development GO:0007417 123 0.020
ncrna metabolic process GO:0034660 108 0.020
histone modification GO:0016570 251 0.020
embryo development ending in birth or egg hatching GO:0009792 34 0.019
nuclear import GO:0051170 106 0.019
cell projection organization GO:0030030 252 0.019
secretion GO:0046903 254 0.019
positive regulation of phosphorylation GO:0042327 394 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
regulation of cell cycle process GO:0010564 266 0.019
cytoplasmic transport GO:0016482 379 0.018
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.018
negative regulation of mitotic cell cycle GO:0045930 102 0.018
positive regulation of developmental process GO:0051094 314 0.018
negative regulation of cell cycle GO:0045786 193 0.018
protein maturation GO:0051604 233 0.018
membrane organization GO:0061024 292 0.018
cellular chemical homeostasis GO:0055082 180 0.018
lipid biosynthetic process GO:0008610 177 0.018
regulation of transferase activity GO:0051338 355 0.018
mitotic cell cycle checkpoint GO:0007093 68 0.017
single organism nuclear import GO:1902593 104 0.017
dna integrity checkpoint GO:0031570 71 0.017
cellular component morphogenesis GO:0032989 314 0.017
reproductive process GO:0022414 106 0.017
regulation of intracellular transport GO:0032386 195 0.017
cell cycle phase transition GO:0044770 173 0.017
organelle assembly GO:0070925 176 0.017
cranial nerve development GO:0021545 4 0.017
negative regulation of catabolic process GO:0009895 104 0.017
nucleoside catabolic process GO:0009164 408 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.016
ribonucleotide biosynthetic process GO:0009260 81 0.016
aging GO:0007568 66 0.016
regulation of kinase activity GO:0043549 314 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
protein ubiquitination GO:0016567 314 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
microtubule based process GO:0007017 210 0.016
positive regulation of immune system process GO:0002684 283 0.016
regulation of protein localization GO:0032880 296 0.016
regulation of cell development GO:0060284 161 0.016
response to biotic stimulus GO:0009607 276 0.016
signal transduction in response to dna damage GO:0042770 57 0.016
epithelial cell differentiation GO:0030855 141 0.015
heart process GO:0003015 62 0.015
maturation of 5 8s rrna GO:0000460 8 0.015
mitotic nuclear division GO:0007067 119 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
protein targeting to nucleus GO:0044744 104 0.014
divalent inorganic cation transport GO:0072511 158 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
cellular lipid metabolic process GO:0044255 303 0.014
sex differentiation GO:0007548 45 0.014
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
protein import into nucleus GO:0006606 104 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
purine containing compound biosynthetic process GO:0072522 88 0.014
regulation of mitosis GO:0007088 63 0.014
regulation of cellular component biogenesis GO:0044087 281 0.013
reproductive system development GO:0061458 56 0.013
response to external biotic stimulus GO:0043207 261 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
single organism membrane organization GO:0044802 268 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
spermatid differentiation GO:0048515 4 0.013
single organism reproductive process GO:0044702 98 0.013
immune effector process GO:0002252 159 0.013
positive regulation of cellular protein catabolic process GO:1903364 37 0.013
gene silencing GO:0016458 49 0.013
cellular ion homeostasis GO:0006873 168 0.013
protein stabilization GO:0050821 64 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
cellular homeostasis GO:0019725 196 0.012
positive regulation of peptidase activity GO:0010952 88 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
blastoderm segmentation GO:0007350 2 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
activation of immune response GO:0002253 114 0.012
metal ion transport GO:0030001 272 0.012
positive regulation of cytoplasmic transport GO:1903651 82 0.012
muscle system process GO:0003012 81 0.012
trna splicing via endonucleolytic cleavage and ligation GO:0006388 7 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
cellular calcium ion homeostasis GO:0006874 117 0.012
multicellular organism reproduction GO:0032504 42 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
divalent metal ion transport GO:0070838 152 0.011
regulation of cytokine production GO:0001817 232 0.011
developmental process involved in reproduction GO:0003006 66 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
growth GO:0040007 202 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
peroxisome organization GO:0007031 28 0.011
cytokine secretion GO:0050663 64 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
glial cell migration GO:0008347 4 0.011
cation homeostasis GO:0055080 189 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
optic nerve development GO:0021554 2 0.011
nuclear transport GO:0051169 179 0.011
protein localization to nucleus GO:0034504 136 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
double strand break repair GO:0006302 101 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
ribonucleoprotein complex biogenesis GO:0022613 116 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.010

UCHL3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.131
inherited metabolic disorder DOID:655 242 0.131
amino acid metabolic disorder DOID:9252 50 0.038
immune system disease DOID:2914 155 0.017
disease of mental health DOID:150 70 0.012
developmental disorder of mental health DOID:0060037 29 0.012