Homo sapiens

0 known processes

ZNF408

zinc finger protein 408

(Aliases: FLJ12827)

ZNF408 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.077
regulation of cell cycle GO:0051726 393 0.054
rna processing GO:0006396 255 0.050
organ formation GO:0048645 3 0.047
modification dependent macromolecule catabolic process GO:0043632 212 0.047
post embryonic development GO:0009791 2 0.044
amine metabolic process GO:0009308 44 0.043
heart formation GO:0060914 2 0.042
anatomical structure formation involved in morphogenesis GO:0048646 284 0.041
regulation of cellular ketone metabolic process GO:0010565 50 0.040
locomotory behavior GO:0007626 1 0.040
nervous system development GO:0007399 293 0.040
determination of adult lifespan GO:0008340 2 0.040
cellular macromolecule catabolic process GO:0044265 380 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.039
specification of organ identity GO:0010092 3 0.038
establishment of planar polarity GO:0001736 3 0.038
negative regulation of protein metabolic process GO:0051248 391 0.036
positive regulation of cell death GO:0010942 263 0.036
regulation of cellular amine metabolic process GO:0033238 11 0.036
protein modification by small protein conjugation GO:0032446 342 0.036
cellular component morphogenesis GO:0032989 314 0.036
multicellular organismal aging GO:0010259 3 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
posttranscriptional regulation of gene expression GO:0010608 213 0.034
inner ear morphogenesis GO:0042472 4 0.033
cellular amino acid metabolic process GO:0006520 116 0.033
neuromuscular junction development GO:0007528 3 0.032
mrna metabolic process GO:0016071 175 0.031
morphogenesis of a polarized epithelium GO:0001738 3 0.031
outflow tract septum morphogenesis GO:0003148 4 0.030
segmentation GO:0035282 4 0.030
spermatid differentiation GO:0048515 4 0.030
establishment of tissue polarity GO:0007164 3 0.030
regulation of synaptic plasticity GO:0048167 3 0.030
negative regulation of programmed cell death GO:0043069 321 0.029
regulation of cell cycle process GO:0010564 266 0.029
negative regulation of cell death GO:0060548 345 0.029
regulation of proteolysis GO:0030162 293 0.029
ubiquitin dependent protein catabolic process GO:0006511 206 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
positive regulation of catabolic process GO:0009896 310 0.027
female gamete generation GO:0007292 2 0.027
negative regulation of cell fate commitment GO:0010454 3 0.027
cellular protein catabolic process GO:0044257 261 0.026
spermatid development GO:0007286 4 0.026
protein maturation GO:0051604 233 0.025
actin filament based process GO:0030029 224 0.025
chromatin modification GO:0016568 298 0.025
cytoplasmic transport GO:0016482 379 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
regulation of cellular component biogenesis GO:0044087 281 0.024
protein processing GO:0016485 226 0.024
ras protein signal transduction GO:0007265 73 0.024
transmembrane transport GO:0055085 399 0.024
cell projection organization GO:0030030 252 0.023
cellular ketone metabolic process GO:0042180 80 0.023
axis elongation GO:0003401 4 0.023
circulatory system development GO:0072359 262 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
regulation of protein maturation GO:1903317 150 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.022
proteasomal protein catabolic process GO:0010498 176 0.022
response to oxygen containing compound GO:1901700 369 0.022
circadian behavior GO:0048512 2 0.022
ncrna processing GO:0034470 83 0.022
nitrogen compound transport GO:0071705 191 0.022
mapk cascade GO:0000165 288 0.022
cellular response to endogenous stimulus GO:0071495 336 0.021
regulation of intracellular transport GO:0032386 195 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
oogenesis GO:0048477 2 0.021
regulation of protein localization GO:0032880 296 0.021
photoreceptor cell differentiation GO:0046530 2 0.020
regulation of transferase activity GO:0051338 355 0.020
cell development GO:0048468 328 0.020
cellular amine metabolic process GO:0044106 41 0.020
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.020
regulation of protein catabolic process GO:0042176 155 0.020
mitotic cell cycle process GO:1903047 286 0.019
taxis GO:0042330 157 0.019
organ induction GO:0001759 4 0.019
immune response GO:0006955 307 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
intracellular protein transport GO:0006886 270 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
regeneration GO:0031099 4 0.019
mitotic cell cycle GO:0000278 326 0.019
regulation of organ formation GO:0003156 4 0.019
apoptotic signaling pathway GO:0097190 268 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
blastoderm segmentation GO:0007350 2 0.018
cell morphogenesis GO:0000902 296 0.018
salivary gland morphogenesis GO:0007435 4 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
negative regulation of protein processing GO:0010955 142 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
ncrna metabolic process GO:0034660 108 0.018
rhythmic behavior GO:0007622 2 0.018
neurotransmitter secretion GO:0007269 4 0.018
endodermal cell fate commitment GO:0001711 4 0.018
regulation of kinase activity GO:0043549 314 0.018
regulation of protein kinase activity GO:0045859 289 0.018
negative regulation of developmental process GO:0051093 247 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
regulation of cellular response to stress GO:0080135 244 0.018
negative regulation of protein maturation GO:1903318 142 0.018
protein catabolic process GO:0030163 325 0.018
rna splicing GO:0008380 131 0.017
negative regulation of proteolysis GO:0045861 132 0.017
actin cytoskeleton organization GO:0030036 207 0.017
cardiac cell fate specification GO:0060912 1 0.017
response to cytokine GO:0034097 232 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.017
cellular protein complex assembly GO:0043623 188 0.017
blood vessel morphogenesis GO:0048514 162 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
cell projection assembly GO:0030031 126 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
translation GO:0006412 132 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.017
positive regulation of transport GO:0051050 336 0.017
innate immune response GO:0045087 178 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
heart field specification GO:0003128 2 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
cell fate determination GO:0001709 3 0.016
negative regulation of cell fate specification GO:0009996 3 0.016
dephosphorylation GO:0016311 209 0.016
protein localization to organelle GO:0033365 280 0.016
organelle assembly GO:0070925 176 0.016
cell part morphogenesis GO:0032990 137 0.016
cell growth GO:0016049 160 0.016
regulation of cardioblast differentiation GO:0051890 4 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
anterior posterior axis specification GO:0009948 2 0.016
cell projection morphogenesis GO:0048858 129 0.016
regulation of cellular protein catabolic process GO:1903362 96 0.016
regulation of protein processing GO:0070613 150 0.016
cellular component assembly involved in morphogenesis GO:0010927 73 0.015
associative learning GO:0008306 1 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
motor neuron axon guidance GO:0008045 2 0.015
nucleoside phosphate catabolic process GO:1901292 412 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
regulation of heart morphogenesis GO:2000826 4 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
regulation of binding GO:0051098 111 0.015
cilium organization GO:0044782 68 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
gtp catabolic process GO:0006184 237 0.015
cell activation GO:0001775 213 0.015
rho protein signal transduction GO:0007266 26 0.015
regulation of response to external stimulus GO:0032101 222 0.015
single organism cellular localization GO:1902580 332 0.015
wnt signaling pathway GO:0016055 156 0.015
protein targeting GO:0006605 187 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
microtubule based process GO:0007017 210 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
startle response GO:0001964 3 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
visual behavior GO:0007632 2 0.014
maintenance of location GO:0051235 112 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
epithelial cell migration GO:0010631 119 0.014
vesicle mediated transport GO:0016192 371 0.014
regulation of heart induction GO:0090381 2 0.014
positive regulation of cell cycle process GO:0090068 106 0.014
regulation of proteasomal protein catabolic process GO:0061136 87 0.014
cardiovascular system development GO:0072358 262 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
behavior GO:0007610 112 0.014
chromosome segregation GO:0007059 114 0.014
memory GO:0007613 3 0.014
peripheral nervous system development GO:0007422 2 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
tissue regeneration GO:0042246 3 0.014
regulation of translation GO:0006417 89 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
protein ubiquitination GO:0016567 314 0.013
positive regulation of immune system process GO:0002684 283 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.013
negative regulation of cell cycle GO:0045786 193 0.013
regulation of immune response GO:0050776 201 0.013
regulation of growth GO:0040008 165 0.013
anion transport GO:0006820 161 0.013
epidermis morphogenesis GO:0048730 3 0.013
positive regulation of organelle organization GO:0010638 195 0.013
defense response GO:0006952 315 0.013
positive regulation of kinase activity GO:0033674 204 0.013
regulation of cytokine production GO:0001817 232 0.013
system process GO:0003008 349 0.013
protein polyubiquitination GO:0000209 110 0.013
neurogenesis GO:0022008 169 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
nuclear transport GO:0051169 179 0.013
epithelium development GO:0060429 227 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
oocyte development GO:0048599 1 0.013
positive regulation of transferase activity GO:0051347 227 0.013
nucleoside triphosphate metabolic process GO:0009141 422 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
negative regulation of cardioblast differentiation GO:0051892 2 0.013
interspecies interaction between organisms GO:0044419 156 0.013
response to external biotic stimulus GO:0043207 261 0.013
cardioblast cell fate commitment GO:0042684 1 0.013
epithelium migration GO:0090132 119 0.013
ion transmembrane transport GO:0034220 338 0.012
chemical homeostasis GO:0048878 306 0.012
response to abiotic stimulus GO:0009628 336 0.012
biological adhesion GO:0022610 331 0.012
negative regulation of protein modification process GO:0031400 200 0.012
protein localization to membrane GO:0072657 160 0.012
response to radiation GO:0009314 151 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
adult locomotory behavior GO:0008344 1 0.012
retinal ganglion cell axon guidance GO:0031290 2 0.012
regulation of transcription during mitosis GO:0045896 2 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
metencephalon development GO:0022037 2 0.012
mrna processing GO:0006397 133 0.012
membrane organization GO:0061024 292 0.012
positive regulation of intracellular transport GO:0032388 104 0.012
cell cell signaling GO:0007267 155 0.012
secretion GO:0046903 254 0.012
regulation of rna splicing GO:0043484 62 0.012
chemotaxis GO:0006935 157 0.012
covalent chromatin modification GO:0016569 254 0.012
growth GO:0040007 202 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
positive regulation of cell cycle GO:0045787 140 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
cochlea development GO:0090102 1 0.012
embryonic epithelial tube formation GO:0001838 4 0.012
tripartite regional subdivision GO:0007351 2 0.012
chromatin organization GO:0006325 351 0.012
response to lipid GO:0033993 206 0.012
positive regulation of developmental process GO:0051094 314 0.011
axoneme assembly GO:0035082 3 0.011
positive regulation of transcription during mitosis GO:0045897 2 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
myosin filament organization GO:0031033 2 0.011
neural tube formation GO:0001841 3 0.011
myosin filament assembly GO:0031034 2 0.011
regulation of dephosphorylation GO:0035303 96 0.011
cilium morphogenesis GO:0060271 75 0.011
oocyte differentiation GO:0009994 2 0.011
cilium assembly GO:0042384 63 0.011
response to hormone GO:0009725 175 0.011
single organism membrane organization GO:0044802 268 0.011
regulation of cell substrate adhesion GO:0010810 68 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
regulation of meiosis GO:0040020 3 0.011
dna replication GO:0006260 116 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.011
vasculature development GO:0001944 181 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
histone modification GO:0016570 251 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
ossification GO:0001503 121 0.011
regulation of dna metabolic process GO:0051052 153 0.011
phototransduction GO:0007602 3 0.011
response to growth factor GO:0070848 205 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
response to fungus GO:0009620 4 0.011
neurological system process GO:0050877 163 0.011
organic acid transport GO:0015849 65 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
purine containing compound catabolic process GO:0072523 411 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
tube closure GO:0060606 3 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
rna interference GO:0016246 4 0.010
positive regulation of proteolysis GO:0045862 142 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
cochlea morphogenesis GO:0090103 1 0.010
meiotic chromosome segregation GO:0045132 4 0.010
postsynaptic membrane organization GO:0001941 2 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.010
negative regulation of kinase activity GO:0033673 106 0.010
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.010
compound eye development GO:0048749 1 0.010
cell cycle phase transition GO:0044770 173 0.010
neuron fate commitment GO:0048663 2 0.010
heart induction GO:0003129 4 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
lipid biosynthetic process GO:0008610 177 0.010
negative regulation of catabolic process GO:0009895 104 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
dna conformation change GO:0071103 113 0.010
regulation of cell differentiation GO:0045595 393 0.010
purine ribonucleotide catabolic process GO:0009154 404 0.010
myoblast fusion GO:0007520 1 0.010
ribonucleotide catabolic process GO:0009261 405 0.010
tissue migration GO:0090130 119 0.010
t cell differentiation in thymus GO:0033077 4 0.010
protein localization to nucleus GO:0034504 136 0.010
cell division GO:0051301 168 0.010

ZNF408 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.037
connective tissue disease DOID:65 109 0.025
bone disease DOID:0080001 88 0.022
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
disease of cellular proliferation DOID:14566 174 0.018
cancer DOID:162 167 0.017
organ system cancer DOID:0050686 164 0.017
sensory system disease DOID:0050155 203 0.015
retinal disease DOID:5679 118 0.012
retinal degeneration DOID:8466 89 0.012
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.012
disease of metabolism DOID:0014667 295 0.012