Homo sapiens

0 known processes

PREP

prolyl endopeptidase

(Aliases: MGC16060,PEP,PE)

PREP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.120
determination of adult lifespan GO:0008340 2 0.119
cellular amino acid metabolic process GO:0006520 116 0.095
multicellular organismal aging GO:0010259 3 0.084
oogenesis GO:0048477 2 0.061
cellular macromolecular complex assembly GO:0034622 324 0.058
locomotory behavior GO:0007626 1 0.057
cellular ketone metabolic process GO:0042180 80 0.056
female gamete generation GO:0007292 2 0.056
cellular amine metabolic process GO:0044106 41 0.051
mitotic cell cycle GO:0000278 326 0.051
amine metabolic process GO:0009308 44 0.050
regulation of cellular amine metabolic process GO:0033238 11 0.049
vesicle mediated transport GO:0016192 371 0.047
positive regulation of developmental process GO:0051094 314 0.047
cytoplasmic transport GO:0016482 379 0.046
single organism cellular localization GO:1902580 332 0.046
cellular protein complex assembly GO:0043623 188 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
mitotic cell cycle process GO:1903047 286 0.042
oocyte differentiation GO:0009994 2 0.042
single organism membrane organization GO:0044802 268 0.041
oocyte development GO:0048599 1 0.040
protein processing GO:0016485 226 0.039
cell development GO:0048468 328 0.039
adult locomotory behavior GO:0008344 1 0.038
regulation of cellular ketone metabolic process GO:0010565 50 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
protein localization to organelle GO:0033365 280 0.037
anterior posterior axis specification GO:0009948 2 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
anatomical structure formation involved in morphogenesis GO:0048646 284 0.036
carbohydrate metabolic process GO:0005975 207 0.035
actin filament based process GO:0030029 224 0.035
blastoderm segmentation GO:0007350 2 0.035
negative regulation of protein metabolic process GO:0051248 391 0.035
maintenance of location GO:0051235 112 0.034
cellular response to dna damage stimulus GO:0006974 379 0.033
segmentation GO:0035282 4 0.033
defense response GO:0006952 315 0.033
system process GO:0003008 349 0.032
immune response GO:0006955 307 0.031
response to oxygen containing compound GO:1901700 369 0.031
regulation of peptidase activity GO:0052547 180 0.031
purine nucleoside triphosphate catabolic process GO:0009146 392 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.030
regulation of cell cycle GO:0051726 393 0.030
positive regulation of cellular component organization GO:0051130 376 0.030
dephosphorylation GO:0016311 209 0.029
regulation of anatomical structure morphogenesis GO:0022603 286 0.029
regulation of cell differentiation GO:0045595 393 0.028
cellular component morphogenesis GO:0032989 314 0.028
anion transport GO:0006820 161 0.028
intracellular protein transport GO:0006886 270 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
oxidation reduction process GO:0055114 396 0.028
regulation of proteolysis GO:0030162 293 0.028
lipid metabolic process GO:0006629 381 0.027
microtubule cytoskeleton organization GO:0000226 176 0.027
protein modification by small protein conjugation GO:0032446 342 0.027
growth GO:0040007 202 0.027
protein maturation GO:0051604 233 0.027
ras protein signal transduction GO:0007265 73 0.027
regulation of cell cycle process GO:0010564 266 0.026
cell morphogenesis GO:0000902 296 0.026
sulfur compound metabolic process GO:0006790 101 0.026
negative regulation of catalytic activity GO:0043086 335 0.026
innate immune response GO:0045087 178 0.025
nucleoside phosphate catabolic process GO:1901292 412 0.025
nucleoside catabolic process GO:0009164 408 0.025
membrane organization GO:0061024 292 0.025
positive regulation of transport GO:0051050 336 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
purine nucleotide catabolic process GO:0006195 405 0.025
cell projection organization GO:0030030 252 0.025
hindbrain development GO:0030902 3 0.024
transmembrane transport GO:0055085 399 0.024
covalent chromatin modification GO:0016569 254 0.024
regulation of mitotic cell cycle GO:0007346 189 0.024
cellular macromolecule catabolic process GO:0044265 380 0.024
cell adhesion GO:0007155 325 0.024
regulation of protein localization GO:0032880 296 0.024
cellular lipid metabolic process GO:0044255 303 0.024
biological adhesion GO:0022610 331 0.024
spermatid differentiation GO:0048515 4 0.024
nucleotide catabolic process GO:0009166 408 0.024
ion transmembrane transport GO:0034220 338 0.024
purine containing compound catabolic process GO:0072523 411 0.024
regulation of endopeptidase activity GO:0052548 170 0.023
small gtpase mediated signal transduction GO:0007264 78 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
nerve development GO:0021675 4 0.023
neuromuscular junction development GO:0007528 3 0.023
negative regulation of multicellular organismal process GO:0051241 317 0.022
regulation of growth GO:0040008 165 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
endomembrane system organization GO:0010256 196 0.022
nervous system development GO:0007399 293 0.022
organophosphate catabolic process GO:0046434 430 0.021
cation transmembrane transport GO:0098655 238 0.021
epithelium development GO:0060429 227 0.021
cation transport GO:0006812 331 0.021
spermatid development GO:0007286 4 0.021
anterior posterior axis specification embryo GO:0008595 2 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
negative regulation of cell cycle GO:0045786 193 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
response to abiotic stimulus GO:0009628 336 0.020
cardiac muscle cell contraction GO:0086003 4 0.020
tripartite regional subdivision GO:0007351 2 0.020
metal ion transport GO:0030001 272 0.020
negative regulation of cell death GO:0060548 345 0.020
regeneration GO:0031099 4 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
regulation of transferase activity GO:0051338 355 0.020
gtp catabolic process GO:0006184 237 0.020
generation of neurons GO:0048699 152 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
positive regulation of cell death GO:0010942 263 0.020
protein catabolic process GO:0030163 325 0.020
lipid localization GO:0010876 106 0.019
regulation of nucleoside metabolic process GO:0009118 209 0.019
regulation of cellular component movement GO:0051270 334 0.019
neuron differentiation GO:0030182 138 0.019
actin cytoskeleton organization GO:0030036 207 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
embryo development GO:0009790 123 0.019
lipid biosynthetic process GO:0008610 177 0.019
gtp metabolic process GO:0046039 239 0.019
regulation of protein transport GO:0051223 213 0.019
ribonucleotide catabolic process GO:0009261 405 0.019
sleep GO:0030431 2 0.019
organic anion transport GO:0015711 103 0.019
nitrogen compound transport GO:0071705 191 0.019
ribonucleoside catabolic process GO:0042454 406 0.019
muscle system process GO:0003012 81 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
single organism nuclear import GO:1902593 104 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
cell cycle phase transition GO:0044770 173 0.018
microtubule based process GO:0007017 210 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
regulation of cell development GO:0060284 161 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
cell projection morphogenesis GO:0048858 129 0.018
translation GO:0006412 132 0.018
regulation of cell migration GO:0030334 289 0.018
secretion by cell GO:0032940 226 0.018
negative regulation of developmental process GO:0051093 247 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
myosin filament assembly GO:0031034 2 0.017
protein targeting GO:0006605 187 0.017
negative regulation of protein modification process GO:0031400 200 0.017
memory GO:0007613 3 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
cellular homeostasis GO:0019725 196 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
peripheral nervous system development GO:0007422 2 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
regulation of cell adhesion GO:0030155 166 0.017
ion homeostasis GO:0050801 230 0.017
histone modification GO:0016570 251 0.017
regulation of intracellular transport GO:0032386 195 0.017
neurological system process GO:0050877 163 0.017
multi organism cellular process GO:0044764 156 0.017
nuclear division GO:0000280 128 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
regulation of locomotion GO:0040012 329 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.016
regulation of establishment of protein localization GO:0070201 242 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
chemical homeostasis GO:0048878 306 0.016
positive regulation of organelle organization GO:0010638 195 0.016
protein ubiquitination GO:0016567 314 0.016
protein localization to nucleus GO:0034504 136 0.016
regulation of protein kinase activity GO:0045859 289 0.016
positive regulation of peptidase activity GO:0010952 88 0.016
epithelial cell differentiation GO:0030855 141 0.016
guanosine containing compound metabolic process GO:1901068 244 0.016
monocarboxylic acid metabolic process GO:0032787 185 0.016
response to cytokine GO:0034097 232 0.016
intracellular mrna localization GO:0008298 1 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
positive regulation of catabolic process GO:0009896 310 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
circulatory system development GO:0072359 262 0.016
neurogenesis GO:0022008 169 0.016
regulation of meiotic cell cycle GO:0051445 4 0.016
cellular protein catabolic process GO:0044257 261 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
muscle structure development GO:0061061 98 0.015
actin filament based movement GO:0030048 17 0.015
regulation of kinase activity GO:0043549 314 0.015
chromatin organization GO:0006325 351 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
striated muscle myosin thick filament assembly GO:0071688 2 0.015
compound eye development GO:0048749 1 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
nuclear migration GO:0007097 1 0.015
glycoprotein biosynthetic process GO:0009101 91 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
cellular cation homeostasis GO:0030003 163 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
cell growth GO:0016049 160 0.015
myosin filament organization GO:0031033 2 0.015
actin mediated cell contraction GO:0070252 12 0.015
cell part morphogenesis GO:0032990 137 0.015
organonitrogen compound biosynthetic process GO:1901566 200 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
protein acylation GO:0043543 138 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
regulation of cell cycle phase transition GO:1901987 126 0.015
regulation of protein maturation GO:1903317 150 0.015
viral process GO:0016032 146 0.015
signal transduction by phosphorylation GO:0023014 297 0.014
divalent metal ion transport GO:0070838 152 0.014
interspecies interaction between organisms GO:0044419 156 0.014
regulation of multi organism process GO:0043900 157 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
cerebral cortex cell migration GO:0021795 3 0.014
maintenance of location in cell GO:0051651 62 0.014
positive regulation of protein transport GO:0051222 135 0.014
cellular component assembly involved in morphogenesis GO:0010927 73 0.014
regulation of cytokine production GO:0001817 232 0.014
response to nitrogen compound GO:1901698 184 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
secretion GO:0046903 254 0.014
chemotaxis GO:0006935 157 0.014
negative regulation of proteolysis GO:0045861 132 0.014
regulation of cellular component biogenesis GO:0044087 281 0.014
regulation of protein processing GO:0070613 150 0.014
lipid transport GO:0006869 90 0.014
endosomal transport GO:0016197 129 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
cerebral cortex radially oriented cell migration GO:0021799 1 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
positive regulation of immune system process GO:0002684 283 0.014
organelle assembly GO:0070925 176 0.014
protein import GO:0017038 130 0.014
regulation of cell motility GO:2000145 299 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
coenzyme metabolic process GO:0006732 65 0.014
organelle fission GO:0048285 149 0.014
cation homeostasis GO:0055080 189 0.014
regulation of translation GO:0006417 89 0.014
endocytosis GO:0006897 159 0.014
protein dephosphorylation GO:0006470 81 0.014
glycoprotein metabolic process GO:0009100 110 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
cardiovascular system development GO:0072358 262 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
response to other organism GO:0051707 261 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
positive regulation of proteolysis GO:0045862 142 0.013
organic acid biosynthetic process GO:0016053 97 0.013
hemopoiesis GO:0030097 180 0.013
response to biotic stimulus GO:0009607 276 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of secretion GO:0051046 194 0.013
regulation of response to external stimulus GO:0032101 222 0.013
associative learning GO:0008306 1 0.013
organic acid transport GO:0015849 65 0.013
carboxylic acid biosynthetic process GO:0046394 97 0.013
divalent inorganic cation transport GO:0072511 158 0.013
cellular metal ion homeostasis GO:0006875 146 0.013
regulation of gtpase activity GO:0043087 180 0.013
multicellular organismal response to stress GO:0033555 1 0.013
apoptotic signaling pathway GO:0097190 268 0.013
limbic system development GO:0021761 3 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
developmental programmed cell death GO:0010623 3 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.013
taxis GO:0042330 157 0.013
positive regulation of cell differentiation GO:0045597 211 0.012
cell division GO:0051301 168 0.012
protein import into nucleus GO:0006606 104 0.012
muscle contraction GO:0006936 73 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
zymogen activation GO:0031638 70 0.012
carboxylic acid transport GO:0046942 63 0.012
neuron development GO:0048666 113 0.012
response to external biotic stimulus GO:0043207 261 0.012
metal ion homeostasis GO:0055065 169 0.012
behavior GO:0007610 112 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
mrna metabolic process GO:0016071 175 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
protein glycosylation GO:0006486 62 0.012
circulatory system process GO:0003013 113 0.012
nuclear import GO:0051170 106 0.012
striated muscle contraction GO:0006941 52 0.012
regulation of viral process GO:0050792 103 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
tissue homeostasis GO:0001894 63 0.012
immune effector process GO:0002252 159 0.012
nuclear transport GO:0051169 179 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
rna interference GO:0016246 4 0.012
glycosylation GO:0070085 71 0.012
cell fate determination GO:0001709 3 0.012
chromatin modification GO:0016568 298 0.012
small molecule biosynthetic process GO:0044283 157 0.012
cellular ion homeostasis GO:0006873 168 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
immune system development GO:0002520 195 0.012
fatty acid metabolic process GO:0006631 115 0.012
nucleus localization GO:0051647 1 0.012
cellular chemical homeostasis GO:0055082 180 0.012
single organism cell adhesion GO:0098602 179 0.012
engulfment of apoptotic cell GO:0043652 2 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
regulation of immune response GO:0050776 201 0.012
regulation of secretion by cell GO:1903530 177 0.012
neuron projection development GO:0031175 106 0.012
calcium ion transport GO:0006816 147 0.012
regulation of cell division GO:0051302 116 0.011
cofactor biosynthetic process GO:0051188 31 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
negative regulation of protein processing GO:0010955 142 0.011
motor neuron axon guidance GO:0008045 2 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.011
ribonucleoprotein complex subunit organization GO:0071826 81 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
wound healing GO:0042060 115 0.011
rho protein signal transduction GO:0007266 26 0.011
establishment of nucleus localization GO:0040023 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
cofactor metabolic process GO:0051186 87 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
sulfur compound biosynthetic process GO:0044272 38 0.011
mitotic nuclear division GO:0007067 119 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
blood vessel development GO:0001568 172 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
protein localization to membrane GO:0072657 160 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
regulation of heart growth GO:0060420 4 0.011
sensory perception of pain GO:0019233 4 0.011
response to wounding GO:0009611 168 0.011
cytokine production GO:0001816 247 0.011
response to organic cyclic compound GO:0014070 204 0.011
cardiac muscle contraction GO:0060048 34 0.011
sister chromatid segregation GO:0000819 54 0.011
blood vessel morphogenesis GO:0048514 162 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
hippocampus development GO:0021766 1 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
positive regulation of secretion GO:0051047 116 0.011
cell substrate adhesion GO:0031589 132 0.011
regulation of protein catabolic process GO:0042176 155 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
cellular response to external stimulus GO:0071496 111 0.011
rhythmic behavior GO:0007622 2 0.011
small molecule catabolic process GO:0044282 92 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
protein targeting to nucleus GO:0044744 104 0.011
response to fungus GO:0009620 4 0.011
mapk cascade GO:0000165 288 0.011
proteasomal protein catabolic process GO:0010498 176 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
negative regulation of protein maturation GO:1903318 142 0.010
peptidyl lysine modification GO:0018205 144 0.010
response to organonitrogen compound GO:0010243 156 0.010
tissue regeneration GO:0042246 3 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
regulation of homeostatic process GO:0032844 121 0.010
reproductive process GO:0022414 106 0.010
response to radiation GO:0009314 151 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.010
nucleus organization GO:0006997 28 0.010
meiosis i GO:0007127 4 0.010
methylation GO:0032259 106 0.010
single organism reproductive process GO:0044702 98 0.010
regulation of ion transport GO:0043269 189 0.010
eye photoreceptor cell differentiation GO:0001754 2 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
morphogenesis of embryonic epithelium GO:0016331 4 0.010
cellular amide metabolic process GO:0043603 69 0.010
organ morphogenesis GO:0009887 147 0.010
chromosome segregation GO:0007059 114 0.010
meiotic chromosome segregation GO:0045132 4 0.010
somatic muscle development GO:0007525 1 0.010
regulation of cell growth GO:0001558 135 0.010

PREP disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.027
nervous system disease DOID:863 431 0.027
disease of metabolism DOID:0014667 295 0.025
musculoskeletal system disease DOID:17 223 0.023
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.017
sensory system disease DOID:0050155 203 0.016
neurodegenerative disease DOID:1289 102 0.016
immune system disease DOID:2914 155 0.014
eye and adnexa disease DOID:1492 150 0.014
amino acid metabolic disorder DOID:9252 50 0.013
inherited metabolic disorder DOID:655 242 0.013
disease of mental health DOID:150 70 0.013
myopathy DOID:423 104 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
eye disease DOID:5614 149 0.011
neuropathy DOID:870 52 0.011
brain disease DOID:936 73 0.011
retinal disease DOID:5679 118 0.010
retinal degeneration DOID:8466 89 0.010