Homo sapiens

48 known processes

EIF2A

eukaryotic translation initiation factor 2A, 65kDa

(Aliases: MSTP004,EIF-2A,MSTP089,MST089)

EIF2A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.564
regulation of cell cycle GO:0051726 393 0.164
translation GO:0006412 132 0.107
mitotic cell cycle GO:0000278 326 0.084
ncrna metabolic process GO:0034660 108 0.065
mitotic cell cycle process GO:1903047 286 0.064
vesicle mediated transport GO:0016192 371 0.056
cellular amino acid metabolic process GO:0006520 116 0.055
ribonucleoprotein complex biogenesis GO:0022613 116 0.054
nuclear division GO:0000280 128 0.050
single organism membrane organization GO:0044802 268 0.050
cellular component morphogenesis GO:0032989 314 0.044
purine containing compound catabolic process GO:0072523 411 0.044
rrna metabolic process GO:0016072 40 0.044
chromatin organization GO:0006325 351 0.043
protein localization to membrane GO:0072657 160 0.043
single organism cellular localization GO:1902580 332 0.041
nervous system development GO:0007399 293 0.039
protein processing GO:0016485 226 0.039
cytoplasmic transport GO:0016482 379 0.038
oogenesis GO:0048477 2 0.038
regulation of mitotic cell cycle GO:0007346 189 0.036
meiosis i GO:0007127 4 0.036
organelle fission GO:0048285 149 0.035
establishment of protein localization to organelle GO:0072594 172 0.035
negative regulation of catalytic activity GO:0043086 335 0.035
regulation of cell cycle process GO:0010564 266 0.034
mitotic cell cycle phase transition GO:0044772 162 0.034
regulation of mitotic cell cycle phase transition GO:1901990 118 0.033
protein targeting GO:0006605 187 0.033
positive regulation of hydrolase activity GO:0051345 331 0.032
posttranscriptional regulation of gene expression GO:0010608 213 0.031
embryo development GO:0009790 123 0.031
cellular macromolecule catabolic process GO:0044265 380 0.030
mitochondrion organization GO:0007005 156 0.029
ribonucleotide catabolic process GO:0009261 405 0.029
cellular response to endogenous stimulus GO:0071495 336 0.029
membrane organization GO:0061024 292 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.027
cell cycle phase transition GO:0044770 173 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
nucleotide catabolic process GO:0009166 408 0.026
multicellular organismal aging GO:0010259 3 0.026
organophosphate catabolic process GO:0046434 430 0.025
endocytosis GO:0006897 159 0.025
negative regulation of protein metabolic process GO:0051248 391 0.025
negative regulation of apoptotic process GO:0043066 316 0.025
female gamete generation GO:0007292 2 0.024
cell morphogenesis GO:0000902 296 0.024
negative regulation of cell cycle GO:0045786 193 0.024
double strand break repair GO:0006302 101 0.024
chromatin modification GO:0016568 298 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
somitogenesis GO:0001756 2 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.023
histone modification GO:0016570 251 0.022
oocyte development GO:0048599 1 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
amine metabolic process GO:0009308 44 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
protein oligomerization GO:0051259 173 0.022
cell projection morphogenesis GO:0048858 129 0.022
determination of adult lifespan GO:0008340 2 0.021
cellular amine metabolic process GO:0044106 41 0.021
establishment of protein localization to membrane GO:0090150 121 0.021
segmentation GO:0035282 4 0.021
apoptotic signaling pathway GO:0097190 268 0.021
nucleoside catabolic process GO:0009164 408 0.021
protein maturation GO:0051604 233 0.021
reproduction GO:0000003 63 0.021
protein targeting to membrane GO:0006612 42 0.021
regulation of cellular component movement GO:0051270 334 0.021
cellular macromolecular complex assembly GO:0034622 324 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
cellular ketone metabolic process GO:0042180 80 0.020
regulation of cell cycle phase transition GO:1901987 126 0.020
organic acid biosynthetic process GO:0016053 97 0.019
protein homooligomerization GO:0051260 100 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
establishment of protein localization to mitochondrion GO:0072655 22 0.019
cell projection organization GO:0030030 252 0.019
nucleocytoplasmic transport GO:0006913 176 0.019
cell development GO:0048468 328 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
multi organism cellular process GO:0044764 156 0.019
regulation of translational elongation GO:0006448 2 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
mrna catabolic process GO:0006402 56 0.019
regulation of peptidase activity GO:0052547 180 0.019
generation of neurons GO:0048699 152 0.019
cellular protein complex assembly GO:0043623 188 0.018
gtp catabolic process GO:0006184 237 0.018
intracellular protein transport GO:0006886 270 0.018
neurogenesis GO:0022008 169 0.018
purine nucleoside catabolic process GO:0006152 398 0.018
negative regulation of cell cycle phase transition GO:1901988 89 0.018
rrna processing GO:0006364 35 0.018
muscle structure development GO:0061061 98 0.018
nuclear transport GO:0051169 179 0.017
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
response to nitrogen compound GO:1901698 184 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
ribosome biogenesis GO:0042254 48 0.017
immune response GO:0006955 307 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
cell part morphogenesis GO:0032990 137 0.017
regulation of proteolysis GO:0030162 293 0.017
viral life cycle GO:0019058 132 0.016
mrna metabolic process GO:0016071 175 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.016
locomotory behavior GO:0007626 1 0.016
neuron development GO:0048666 113 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
regulation of cell differentiation GO:0045595 393 0.016
regeneration GO:0031099 4 0.016
cell activation GO:0001775 213 0.016
interspecies interaction between organisms GO:0044419 156 0.016
ribonucleoprotein complex subunit organization GO:0071826 81 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
positive regulation of cell death GO:0010942 263 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
negative regulation of cell cycle process GO:0010948 121 0.016
covalent chromatin modification GO:0016569 254 0.016
viral process GO:0016032 146 0.015
rna catabolic process GO:0006401 71 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
oocyte differentiation GO:0009994 2 0.015
positive regulation of endopeptidase activity GO:0010950 84 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.015
response to inorganic substance GO:0010035 127 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
dna repair GO:0006281 198 0.015
regulation of protein localization GO:0032880 296 0.015
gtp metabolic process GO:0046039 239 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
guanosine containing compound metabolic process GO:1901068 244 0.015
neuron differentiation GO:0030182 138 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.014
nuclear transcribed mrna catabolic process GO:0000956 48 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
regulation of gtpase activity GO:0043087 180 0.014
regulation of cellular ketone metabolic process GO:0010565 50 0.014
secretion by cell GO:0032940 226 0.014
system process GO:0003008 349 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
secretion GO:0046903 254 0.014
regulation of multi organism process GO:0043900 157 0.014
rhythmic behavior GO:0007622 2 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
immune system development GO:0002520 195 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
neuromuscular junction development GO:0007528 3 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
ribonucleoprotein complex assembly GO:0022618 78 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
neurotransmitter secretion GO:0007269 4 0.014
sex differentiation GO:0007548 45 0.013
embryo development ending in birth or egg hatching GO:0009792 34 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
regulation of protein kinase activity GO:0045859 289 0.013
memory GO:0007613 3 0.013
negative regulation of mitotic cell cycle GO:0045930 102 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
negative regulation of protein processing GO:0010955 142 0.012
dephosphorylation GO:0016311 209 0.012
leukocyte activation GO:0045321 164 0.012
protein localization to organelle GO:0033365 280 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
mitotic nuclear division GO:0007067 119 0.012
cell growth GO:0016049 160 0.012
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 3 0.012
transmembrane transport GO:0055085 399 0.012
mating GO:0007618 1 0.012
cell division GO:0051301 168 0.012
regulation of protein processing GO:0070613 150 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
tissue regeneration GO:0042246 3 0.012
hemopoiesis GO:0030097 180 0.011
spermatid development GO:0007286 4 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
blastoderm segmentation GO:0007350 2 0.011
spermatid differentiation GO:0048515 4 0.011
anterior posterior axis specification GO:0009948 2 0.011
wound healing GO:0042060 115 0.011
hindbrain development GO:0030902 3 0.011
response to oxygen containing compound GO:1901700 369 0.011
negative regulation of phosphatase activity GO:0010923 61 0.011
regulation of dephosphorylation GO:0035303 96 0.011
translational initiation GO:0006413 48 0.011
ribosomal large subunit biogenesis GO:0042273 10 0.011
organelle assembly GO:0070925 176 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
response to wounding GO:0009611 168 0.011
neuron projection development GO:0031175 106 0.011
myosin filament organization GO:0031033 2 0.011
cardiovascular system development GO:0072358 262 0.011
positive regulation of catabolic process GO:0009896 310 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
reproductive structure development GO:0048608 55 0.011
negative regulation of cell death GO:0060548 345 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.010
microtubule based process GO:0007017 210 0.010
regulation of cellular response to stress GO:0080135 244 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
growth GO:0040007 202 0.010
mrna processing GO:0006397 133 0.010
chromosome segregation GO:0007059 114 0.010
rna processing GO:0006396 255 0.010
endomembrane system organization GO:0010256 196 0.010

EIF2A disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.017
musculoskeletal system disease DOID:17 223 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
disease of metabolism DOID:0014667 295 0.011