Homo sapiens

20 known processes

PPP6R1

protein phosphatase 6, regulatory subunit 1

(Aliases: SAP190,PP6R1,SAPS1,MGC138185,KIAA1115,MGC142003)

PPP6R1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of canonical wnt signaling pathway GO:0060828 88 0.912
negative regulation of wnt signaling pathway GO:0030178 69 0.543
nucleoside triphosphate catabolic process GO:0009143 394 0.217
rab protein signal transduction GO:0032482 4 0.203
actin filament based process GO:0030029 224 0.186
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.172
positive regulation of catabolic process GO:0009896 310 0.161
rna processing GO:0006396 255 0.147
regulation of dephosphorylation GO:0035303 96 0.140
negative regulation of striated muscle contraction GO:0045988 2 0.139
nucleoside catabolic process GO:0009164 408 0.138
mitotic cell cycle GO:0000278 326 0.134
purine nucleoside triphosphate catabolic process GO:0009146 392 0.129
guanosine containing compound metabolic process GO:1901068 244 0.128
canonical wnt signaling pathway GO:0060070 116 0.125
negative regulation of protein metabolic process GO:0051248 391 0.123
post embryonic development GO:0009791 2 0.122
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.122
actin cytoskeleton organization GO:0030036 207 0.120
response to fungus GO:0009620 4 0.115
wnt signaling pathway GO:0016055 156 0.115
ras protein signal transduction GO:0007265 73 0.111
cellular macromolecule catabolic process GO:0044265 380 0.104
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.103
oogenesis GO:0048477 2 0.100
vesicle mediated transport GO:0016192 371 0.100
cytoplasmic transport GO:0016482 379 0.096
tor signaling GO:0031929 39 0.091
purine nucleotide catabolic process GO:0006195 405 0.091
glycosyl compound catabolic process GO:1901658 413 0.086
gtp catabolic process GO:0006184 237 0.085
regulation of small gtpase mediated signal transduction GO:0051056 156 0.084
cell cycle phase transition GO:0044770 173 0.080
female gamete generation GO:0007292 2 0.078
regulation of cellular amine metabolic process GO:0033238 11 0.075
purine nucleoside triphosphate metabolic process GO:0009144 412 0.075
rho protein signal transduction GO:0007266 26 0.072
purine containing compound catabolic process GO:0072523 411 0.072
anion transport GO:0006820 161 0.071
response to external biotic stimulus GO:0043207 261 0.071
protein autophosphorylation GO:0046777 123 0.070
positive regulation of hydrolase activity GO:0051345 331 0.066
response to other organism GO:0051707 261 0.062
purine ribonucleoside catabolic process GO:0046130 398 0.062
covalent chromatin modification GO:0016569 254 0.061
ribonucleoside triphosphate metabolic process GO:0009199 412 0.060
regulation of cellular amino acid metabolic process GO:0006521 6 0.060
small gtpase mediated signal transduction GO:0007264 78 0.060
mitotic cell cycle process GO:1903047 286 0.059
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.058
cellular amine metabolic process GO:0044106 41 0.058
cellular response to oxygen containing compound GO:1901701 276 0.058
ncrna metabolic process GO:0034660 108 0.057
single organism cellular localization GO:1902580 332 0.055
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.055
dephosphorylation GO:0016311 209 0.054
regulation of rab gtpase activity GO:0032313 39 0.054
purine ribonucleotide catabolic process GO:0009154 404 0.053
positive regulation of cellular catabolic process GO:0031331 284 0.053
organic hydroxy compound metabolic process GO:1901615 147 0.053
cellular response to endogenous stimulus GO:0071495 336 0.052
cellular amino acid metabolic process GO:0006520 116 0.052
nucleoside monophosphate metabolic process GO:0009123 191 0.050
negative regulation of programmed cell death GO:0043069 321 0.050
nucleoside triphosphate metabolic process GO:0009141 422 0.049
ribonucleoside triphosphate catabolic process GO:0009203 391 0.049
regulation of purine nucleotide catabolic process GO:0033121 205 0.049
negative regulation of anion channel activity GO:0010360 1 0.048
negative regulation of transport GO:0051051 176 0.048
cellular response to oxidative stress GO:0034599 85 0.048
nucleotide catabolic process GO:0009166 408 0.047
purine nucleoside catabolic process GO:0006152 398 0.046
positive regulation of nucleoside metabolic process GO:0045979 186 0.046
dna repair GO:0006281 198 0.046
protein catabolic process GO:0030163 325 0.046
multicellular organismal aging GO:0010259 3 0.046
positive regulation of gtp catabolic process GO:0033126 166 0.045
cytokine production GO:0001816 247 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
negative regulation of phosphate metabolic process GO:0045936 267 0.044
cellular response to nitrogen compound GO:1901699 144 0.044
protein maturation GO:0051604 233 0.043
regulation of gtpase activity GO:0043087 180 0.042
positive regulation of nucleotide catabolic process GO:0030813 185 0.042
amine metabolic process GO:0009308 44 0.041
mrna metabolic process GO:0016071 175 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.039
protein processing GO:0016485 226 0.039
internal protein amino acid acetylation GO:0006475 101 0.039
determination of adult lifespan GO:0008340 2 0.038
positive regulation of cellular amine metabolic process GO:0033240 7 0.038
regulation of nucleotide metabolic process GO:0006140 269 0.037
protein deubiquitination GO:0016579 79 0.036
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.036
chromatin organization GO:0006325 351 0.036
regulation of nucleoside metabolic process GO:0009118 209 0.036
protein modification by small protein conjugation GO:0032446 342 0.035
organophosphate catabolic process GO:0046434 430 0.035
regulation of ras gtpase activity GO:0032318 128 0.033
cellular ketone metabolic process GO:0042180 80 0.033
response to biotic stimulus GO:0009607 276 0.033
peptidyl lysine modification GO:0018205 144 0.033
positive regulation of protein phosphorylation GO:0001934 313 0.033
nervous system development GO:0007399 293 0.032
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.032
g protein coupled receptor signaling pathway GO:0007186 207 0.032
positive regulation of ras gtpase activity GO:0032320 117 0.032
cellular response to dna damage stimulus GO:0006974 379 0.031
guanosine containing compound catabolic process GO:1901069 239 0.031
response to hormone GO:0009725 175 0.031
regulation of rab protein signal transduction GO:0032483 39 0.031
regulation of mitotic cell cycle phase transition GO:1901990 118 0.031
response to nitrogen compound GO:1901698 184 0.031
negative regulation of cell death GO:0060548 345 0.030
internal peptidyl lysine acetylation GO:0018393 97 0.030
microtubule based process GO:0007017 210 0.030
response to organonitrogen compound GO:0010243 156 0.030
mrna processing GO:0006397 133 0.030
mitotic nuclear division GO:0007067 119 0.030
gtp metabolic process GO:0046039 239 0.029
regulation of response to external stimulus GO:0032101 222 0.029
positive regulation of rab gtpase activity GO:0032851 39 0.028
regulation of cellular component biogenesis GO:0044087 281 0.028
regulation of proteolysis GO:0030162 293 0.028
proteasomal protein catabolic process GO:0010498 176 0.028
microtubule cytoskeleton organization GO:0000226 176 0.027
regulation of microtubule based process GO:0032886 74 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
protein acylation GO:0043543 138 0.027
regulation of establishment of protein localization GO:0070201 242 0.027
regulation of ras protein signal transduction GO:0046578 155 0.027
regulation of cell differentiation GO:0045595 393 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
ribonucleoside catabolic process GO:0042454 406 0.026
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.025
cell development GO:0048468 328 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
nuclear transport GO:0051169 179 0.025
ribonucleotide catabolic process GO:0009261 405 0.024
cellular response to organonitrogen compound GO:0071417 124 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
response to oxygen containing compound GO:1901700 369 0.024
cell cycle checkpoint GO:0000075 117 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.023
endomembrane system organization GO:0010256 196 0.023
regulation of rhodopsin mediated signaling pathway GO:0022400 1 0.023
immune response GO:0006955 307 0.022
histone acetylation GO:0016573 93 0.022
cellular response to peptide GO:1901653 59 0.022
phototransduction GO:0007602 3 0.022
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.022
purine nucleoside monophosphate catabolic process GO:0009128 158 0.022
regulation of cytokine production GO:0001817 232 0.022
regulation of mitotic cell cycle GO:0007346 189 0.022
intracellular protein transport GO:0006886 270 0.021
growth GO:0040007 202 0.021
peptidyl serine phosphorylation GO:0018105 101 0.021
negative regulation of apoptotic process GO:0043066 316 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
dna conformation change GO:0071103 113 0.020
protein secretion GO:0009306 98 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
regulation of gtp catabolic process GO:0033124 180 0.020
negative regulation of the force of heart contraction by chemical signal GO:0003108 1 0.020
atp catabolic process GO:0006200 157 0.020
translation GO:0006412 132 0.020
cell cycle g1 s phase transition GO:0044843 80 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
endocytosis GO:0006897 159 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
response to peptide GO:1901652 65 0.020
protein localization to membrane GO:0072657 160 0.020
maintenance of location GO:0051235 112 0.020
single organism reproductive process GO:0044702 98 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
plasma membrane organization GO:0007009 115 0.019
regulation of cell cycle process GO:0010564 266 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.018
peptidyl lysine acetylation GO:0018394 101 0.018
cellular response to extracellular stimulus GO:0031668 72 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
g1 s transition of mitotic cell cycle GO:0000082 78 0.018
response to oxidative stress GO:0006979 121 0.018
regulation of cellular response to stress GO:0080135 244 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
phototransduction visible light GO:0007603 2 0.018
lipid localization GO:0010876 106 0.018
defense response GO:0006952 315 0.018
enzyme linked receptor protein signaling pathway GO:0007167 303 0.018
locomotory behavior GO:0007626 1 0.017
transmembrane transport GO:0055085 399 0.017
mapk cascade GO:0000165 288 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
nucleoside monophosphate catabolic process GO:0009125 159 0.017
cellular response to external stimulus GO:0071496 111 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.017
negative regulation of protein processing GO:0010955 142 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
spermatid development GO:0007286 4 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.016
membrane organization GO:0061024 292 0.016
rna catabolic process GO:0006401 71 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.016
response to interleukin 1 GO:0070555 47 0.016
regulation of rho gtpase activity GO:0032319 66 0.016
regulation of locomotion GO:0040012 329 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
secretion by cell GO:0032940 226 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
cellular protein complex assembly GO:0043623 188 0.016
blastoderm segmentation GO:0007350 2 0.016
reproduction GO:0000003 63 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
neuromuscular junction development GO:0007528 3 0.015
cellular protein catabolic process GO:0044257 261 0.015
spermatid differentiation GO:0048515 4 0.015
peptidyl serine modification GO:0018209 106 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
ribonucleoside monophosphate metabolic process GO:0009161 187 0.015
histone modification GO:0016570 251 0.015
innate immune response GO:0045087 178 0.015
mrna splicing via spliceosome GO:0000398 89 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
atp metabolic process GO:0046034 176 0.015
chromosome segregation GO:0007059 114 0.015
regulation of protein maturation GO:1903317 150 0.015
response to nutrient levels GO:0031667 81 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
head development GO:0060322 108 0.014
cell morphogenesis GO:0000902 296 0.014
regulation of cell motility GO:2000145 299 0.014
nitrogen compound transport GO:0071705 191 0.014
negative regulation of protein transport GO:0051224 75 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
regulation of protein localization GO:0032880 296 0.014
cellular component disassembly GO:0022411 92 0.014
actin filament organization GO:0007015 128 0.014
developmental process involved in reproduction GO:0003006 66 0.014
lipid metabolic process GO:0006629 381 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
protein targeting GO:0006605 187 0.014
anterior posterior axis specification GO:0009948 2 0.014
multi organism cellular process GO:0044764 156 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
response to extracellular stimulus GO:0009991 85 0.013
single organism membrane organization GO:0044802 268 0.013
positive regulation of transferase activity GO:0051347 227 0.013
mrna catabolic process GO:0006402 56 0.013
amino acid transport GO:0006865 28 0.013
trna metabolic process GO:0006399 35 0.013
regulation of cellular component movement GO:0051270 334 0.013
response to abiotic stimulus GO:0009628 336 0.013
adult locomotory behavior GO:0008344 1 0.013
apoptotic signaling pathway GO:0097190 268 0.013
regulation of phosphatase activity GO:0010921 81 0.013
protein import into nucleus GO:0006606 104 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
immune response activating signal transduction GO:0002757 90 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
lymphocyte activation GO:0046649 133 0.013
protein acetylation GO:0006473 116 0.013
regulation of mapk cascade GO:0043408 262 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
cellular homeostasis GO:0019725 196 0.013
oocyte differentiation GO:0009994 2 0.013
tissue migration GO:0090130 119 0.013
rna interference GO:0016246 4 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regeneration GO:0031099 4 0.013
positive regulation of cell migration GO:0030335 172 0.013
regulation of cell cycle GO:0051726 393 0.012
positive regulation of proteolysis GO:0045862 142 0.012
response to cytokine GO:0034097 232 0.012
cation transport GO:0006812 331 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.012
positive regulation of immune response GO:0050778 159 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
positive regulation of rho gtpase activity GO:0032321 56 0.012
intracellular mrna localization GO:0008298 1 0.012
negative regulation of protein modification process GO:0031400 200 0.012
cell aging GO:0007569 52 0.012
chemical homeostasis GO:0048878 306 0.012
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.012
tripartite regional subdivision GO:0007351 2 0.012
regulation of chromosome organization GO:0033044 103 0.012
regulation of protein processing GO:0070613 150 0.012
positive regulation of cell death GO:0010942 263 0.012
negative regulation of cytokine production GO:0001818 82 0.012
organic anion transport GO:0015711 103 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
cardiac muscle contraction GO:0060048 34 0.012
maintenance of protein location GO:0045185 57 0.011
brain development GO:0007420 97 0.011
cellular response to biotic stimulus GO:0071216 71 0.011
regulation of mrna metabolic process GO:1903311 53 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
cell growth GO:0016049 160 0.011
regulation of protein catabolic process GO:0042176 155 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
positive regulation of immune system process GO:0002684 283 0.011
positive regulation of transport GO:0051050 336 0.011
nuclear division GO:0000280 128 0.011
cell division GO:0051301 168 0.011
negative regulation of cell cycle GO:0045786 193 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
organelle localization GO:0051640 84 0.011
rna splicing GO:0008380 131 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
protein complex disassembly GO:0043241 52 0.011
regulation of protein kinase activity GO:0045859 289 0.010
detection of stimulus GO:0051606 85 0.010
receptor internalization GO:0031623 43 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
segmentation GO:0035282 4 0.010
generation of neurons GO:0048699 152 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
regulation of rho protein signal transduction GO:0035023 79 0.010
cellular response to starvation GO:0009267 58 0.010
anatomical structure formation involved in morphogenesis GO:0048646 284 0.010
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
positive regulation of cell cycle process GO:0090068 106 0.010
cellular response to abiotic stimulus GO:0071214 117 0.010
receptor mediated endocytosis GO:0006898 84 0.010
system process GO:0003008 349 0.010
protein dephosphorylation GO:0006470 81 0.010

PPP6R1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011