|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.824
|
Human |
|
|
trail activated apoptotic signaling pathway
|
GO:0036462 |
4 |
0.788
|
Human |
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.735
|
Human |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.557
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.405
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.385
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.377
|
Human |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.375
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.371
|
Human Mouse |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.371
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.368
|
Human |
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.362
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.356
|
Human |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.346
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.336
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.328
|
Human |
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.309
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.281
|
Human |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.276
|
Human |
|
|
limbic system development
|
GO:0021761 |
3 |
0.262
|
|
|
|
response to cobalt ion
|
GO:0032025 |
1 |
0.256
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.253
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.252
|
Human Mouse |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.249
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.246
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.242
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.237
|
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.236
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.232
|
Human |
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.228
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.227
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.221
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.218
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.217
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.216
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.210
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.206
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.203
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.199
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.198
|
Human |
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.178
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.176
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.175
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.172
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.171
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.169
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.168
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.167
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.166
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.165
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.164
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.163
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.151
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.151
|
Human |
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.150
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.140
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.140
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.139
|
Human |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.136
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.136
|
Human |
|
|
positive regulation of macrophage differentiation
|
GO:0045651 |
7 |
0.133
|
Human |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.124
|
Human |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.123
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.123
|
|
|
|
necroptotic process
|
GO:0070266 |
16 |
0.121
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.118
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.117
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.117
|
Human Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.115
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
25 |
0.114
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.112
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.111
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.104
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.104
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.104
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.103
|
Human |
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.101
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.100
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.100
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.099
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.098
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.097
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
7 |
0.095
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
38 |
0.093
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.091
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.091
|
Human |
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.089
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.087
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.087
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.086
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.083
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.082
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.081
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.081
|
Human |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.080
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.080
|
|
|
|
positive regulation of protein k48 linked ubiquitination
|
GO:1902524 |
1 |
0.079
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.079
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.078
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.078
|
Human |
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.078
|
|
|
|
positive regulation of protein monoubiquitination
|
GO:1902527 |
1 |
0.078
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.077
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.077
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.076
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.074
|
Human |
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.072
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.072
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.072
|
Human |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.071
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.071
|
Human |
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.071
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.071
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.069
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.068
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.068
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.067
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.067
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.067
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.067
|
Human |
|
|
response to cocaine
|
GO:0042220 |
1 |
0.067
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.067
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.066
|
Human |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.066
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.066
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.066
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.066
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.065
|
Human Mouse |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.065
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.064
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.064
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
27 |
0.063
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.063
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.063
|
Human |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.063
|
Human |
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.062
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.062
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.062
|
Human |
|
|
cardiac ventricle formation
|
GO:0003211 |
2 |
0.060
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.060
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.060
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.060
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.059
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.059
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.058
|
Mouse |
|
|
regulation of protein linear polyubiquitination
|
GO:1902528 |
2 |
0.058
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.057
|
Human |
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.056
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.055
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.055
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.054
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.054
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.054
|
Human |
|
|
spermatid development
|
GO:0007286 |
4 |
0.054
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.054
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.054
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.054
|
|
|
|
termination of signal transduction
|
GO:0023021 |
3 |
0.053
|
|
|
|
system process
|
GO:0003008 |
349 |
0.053
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.052
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.052
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.052
|
|
|
|
myoblast proliferation
|
GO:0051450 |
1 |
0.051
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.051
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.051
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.050
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.050
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.050
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.049
|
Human |
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.049
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.049
|
|
|
|
macrophage differentiation
|
GO:0030225 |
11 |
0.049
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.049
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.048
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.048
|
Human |
|
|
cochlea development
|
GO:0090102 |
1 |
0.047
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.047
|
|
|
|
b cell homeostasis
|
GO:0001782 |
1 |
0.047
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.047
|
|
|
|
positive regulation of protein k63 linked ubiquitination
|
GO:1902523 |
1 |
0.047
|
|
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.047
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.047
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.046
|
Human |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.045
|
Human |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.045
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.045
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.045
|
Human |
|
|
venous blood vessel development
|
GO:0060841 |
2 |
0.045
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.044
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
12 |
0.044
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.044
|
|
|
|
cellular response to antibiotic
|
GO:0071236 |
1 |
0.044
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.044
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.043
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.043
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.043
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.043
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.042
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.042
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.042
|
Human Mouse |
|
|
positive regulation of protein linear polyubiquitination
|
GO:1902530 |
2 |
0.041
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.041
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.041
|
Mouse |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.041
|
Human |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.040
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.040
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.040
|
Human |
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.040
|
|
|
|
natural killer cell apoptotic process
|
GO:0070246 |
1 |
0.039
|
|
|
|
alditol phosphate metabolic process
|
GO:0052646 |
3 |
0.039
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.039
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.038
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.038
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.038
|
Human |
|
|
response to muramyl dipeptide
|
GO:0032495 |
4 |
0.037
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.037
|
|
|
|
response to xenobiotic stimulus
|
GO:0009410 |
30 |
0.037
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.037
|
|
|
|
positive regulation of dephosphorylation
|
GO:0035306 |
26 |
0.037
|
|
|
|
regulation of protein monoubiquitination
|
GO:1902525 |
1 |
0.037
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.037
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.037
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.036
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.036
|
Human |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.036
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.036
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.036
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.036
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.036
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.035
|
Mouse |
|
|
cell division
|
GO:0051301 |
168 |
0.035
|
|
|
|
cardiac chamber formation
|
GO:0003207 |
2 |
0.035
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.035
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.035
|
Human |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.035
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.035
|
|
|
|
response to amino acid
|
GO:0043200 |
14 |
0.035
|
|
|
|
cellular amino acid biosynthetic process
|
GO:0008652 |
30 |
0.035
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.035
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.035
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.035
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.034
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.034
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.034
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.034
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.034
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.034
|
|
|
|
head development
|
GO:0060322 |
108 |
0.034
|
Human |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.034
|
|
|
|
ruffle assembly
|
GO:0097178 |
10 |
0.034
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.033
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.033
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.033
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.033
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.033
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.033
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.033
|
Human |
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.033
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.032
|
Human |
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
37 |
0.032
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.032
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.032
|
Human |
|
|
cellular response to xenobiotic stimulus
|
GO:0071466 |
29 |
0.032
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.031
|
Human |
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.031
|
Human |
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.031
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.031
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.031
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.031
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.031
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.031
|
Human Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.031
|
Human |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.031
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.030
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.030
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.030
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.030
|
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.029
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.029
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.029
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.029
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.029
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.029
|
|
|
|
nucleoside transport
|
GO:0015858 |
8 |
0.028
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.028
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.028
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.028
|
Human |
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.028
|
Human |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.028
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.028
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.028
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.027
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.027
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.027
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.027
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.027
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.027
|
Human |
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.027
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.026
|
Mouse |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.026
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.026
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.026
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.026
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.026
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.025
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.025
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.025
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.025
|
|
|
|
cellular modified amino acid catabolic process
|
GO:0042219 |
4 |
0.025
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.024
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.024
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.024
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.024
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.024
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.024
|
Human |
|
|
carbohydrate derivative transport
|
GO:1901264 |
20 |
0.024
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.024
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.024
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.023
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.023
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.023
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.023
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.023
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.023
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.023
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.023
|
Human |
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.023
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.023
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.023
|
Human |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.023
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.023
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.023
|
Human |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.023
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.022
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
11 |
0.022
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.022
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.022
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.022
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.022
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.022
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.022
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.021
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.021
|
Human |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.021
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.021
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.021
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.021
|
|
|
|
regulation of protein polyubiquitination
|
GO:1902914 |
8 |
0.021
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.021
|
Human |
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.021
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.021
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
4 |
0.021
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.021
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.021
|
Human |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.021
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.021
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.020
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.020
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.020
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.020
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.020
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.020
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.020
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.020
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.020
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.020
|
Human |
|
|
compound eye development
|
GO:0048749 |
1 |
0.020
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.019
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.019
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.019
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.019
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.019
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.019
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
9 |
0.019
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
6 |
0.019
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.019
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.019
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.019
|
Human |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.019
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.019
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.019
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.019
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.019
|
Human |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.019
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.019
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.018
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
1 |
0.018
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.018
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.018
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.018
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.018
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.018
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.018
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.018
|
|
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.018
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.018
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.018
|
Human Mouse |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.018
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.018
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
1 |
0.018
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.018
|
Human |
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.017
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.017
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.017
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.017
|
Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.017
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.017
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.017
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.017
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.017
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.017
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.017
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.017
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.017
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.017
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.016
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.016
|
|
|
|
mating
|
GO:0007618 |
1 |
0.016
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.016
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.016
|
|
|
|
translation
|
GO:0006412 |
132 |
0.016
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.016
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.016
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.016
|
|
|
|
positive regulation of protein polyubiquitination
|
GO:1902916 |
3 |
0.016
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.016
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.016
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.016
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.016
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.016
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.016
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.016
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.016
|
|
|
|
regulation of nucleoside transport
|
GO:0032242 |
1 |
0.016
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.016
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.016
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
2 |
0.016
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.016
|
Human |
|
|
response to estrogen
|
GO:0043627 |
47 |
0.016
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.016
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.016
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003256 |
3 |
0.016
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.016
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.016
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.016
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.015
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.015
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.015
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.015
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.015
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.015
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.015
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.015
|
|
|
|
sphingolipid biosynthetic process
|
GO:0030148 |
18 |
0.015
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.015
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.015
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.015
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.015
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.015
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.015
|
Human |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.015
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.015
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.015
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.015
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.015
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.015
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.015
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.015
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.015
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.015
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.015
|
Mouse |
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.015
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.015
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.015
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.015
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.015
|
|
|
|
response to dexamethasone
|
GO:0071548 |
1 |
0.015
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.015
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.015
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.015
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.014
|
Human |
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.014
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.014
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.014
|
|
