Homo sapiens

26 known processes

CASP5

caspase 5, apoptosis-related cysteine peptidase

(Aliases: ICEREL-III,ICH-3,ICE(rel)III,MGC141966)

CASP5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to other organism GO:0051707 261 0.207
Fly
defense response GO:0006952 315 0.185
Fly
response to biotic stimulus GO:0009607 276 0.157
Fly
immune response GO:0006955 307 0.154
Fly
positive regulation of immune system process GO:0002684 283 0.148
Human Fly
cytokine production GO:0001816 247 0.142
response to external biotic stimulus GO:0043207 261 0.131
Fly
positive regulation of immune response GO:0050778 159 0.127
Fly
regulation of cytokine production GO:0001817 232 0.111
innate immune response GO:0045087 178 0.109
Fly
cellular amino acid metabolic process GO:0006520 116 0.109
positive regulation of programmed cell death GO:0043068 249 0.103
Zebrafish Fly
biological adhesion GO:0022610 331 0.103
secretion GO:0046903 254 0.102
regulation of protein transport GO:0051223 213 0.101
regulation of defense response GO:0031347 154 0.097
Fly
regulation of immune response GO:0050776 201 0.096
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.094
regulation of secretion by cell GO:1903530 177 0.092
cellular amine metabolic process GO:0044106 41 0.092
regulation of secretion GO:0051046 194 0.091
regulation of protein localization GO:0032880 296 0.087
regulation of cellular amino acid metabolic process GO:0006521 6 0.085
regulation of response to external stimulus GO:0032101 222 0.084
Fly
cell activation GO:0001775 213 0.084
hematopoietic or lymphoid organ development GO:0048534 186 0.082
Human
positive regulation of hydrolase activity GO:0051345 331 0.077
Human Fly
cellular ketone metabolic process GO:0042180 80 0.077
amine metabolic process GO:0009308 44 0.077
cell adhesion GO:0007155 325 0.076
positive regulation of cellular amine metabolic process GO:0033240 7 0.076
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
negative regulation of apoptotic process GO:0043066 316 0.071
Human
regulation of establishment of protein localization GO:0070201 242 0.070
negative regulation of cell death GO:0060548 345 0.070
Human Fly
regulation of cellular amine metabolic process GO:0033238 11 0.068
immune response activating signal transduction GO:0002757 90 0.067
positive regulation of transport GO:0051050 336 0.066
secretion by cell GO:0032940 226 0.065
activation of immune response GO:0002253 114 0.063
defense response to other organism GO:0098542 129 0.063
Fly
positive regulation of cytokine production GO:0001819 167 0.063
immune response regulating signaling pathway GO:0002764 97 0.062
positive regulation of cell proliferation GO:0008284 301 0.061
regulation of cell differentiation GO:0045595 393 0.060
Human
immune system development GO:0002520 195 0.060
Human
regulation of cellular component movement GO:0051270 334 0.059
positive regulation of cell death GO:0010942 263 0.059
Zebrafish Fly
positive regulation of mapk cascade GO:0043410 190 0.059
leukocyte activation GO:0045321 164 0.058
regulation of leukocyte activation GO:0002694 115 0.058
positive regulation of apoptotic process GO:0043065 246 0.057
Zebrafish Fly
response to oxygen containing compound GO:1901700 369 0.057
response to bacterium GO:0009617 144 0.056
Fly
cytokine secretion GO:0050663 64 0.056
regulation of multi organism process GO:0043900 157 0.056
Fly
small gtpase mediated signal transduction GO:0007264 78 0.055
negative regulation of programmed cell death GO:0043069 321 0.055
Human Fly
immune effector process GO:0002252 159 0.054
Fly
regulation of innate immune response GO:0045088 97 0.054
Fly
post embryonic development GO:0009791 2 0.054
negative regulation of cell proliferation GO:0008285 228 0.053
regulation of peptidase activity GO:0052547 180 0.052
Human Fly
regulation of proteolysis GO:0030162 293 0.052
Human Fly
response to cytokine GO:0034097 232 0.052
Human
cd8 positive alpha beta t cell activation GO:0036037 3 0.051
protein maturation GO:0051604 233 0.051
Human Fly
vesicle mediated transport GO:0016192 371 0.050
regulation of lymphocyte activation GO:0051249 103 0.050
lymphocyte activation GO:0046649 133 0.049
regulation of protein secretion GO:0050708 86 0.049
interleukin 12 secretion GO:0072610 1 0.048
regulation of locomotion GO:0040012 329 0.048
response to virus GO:0009615 126 0.048
Fly
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.048
regulation of cytokine secretion GO:0050707 57 0.048
negative regulation of protein metabolic process GO:0051248 391 0.048
positive regulation of cell differentiation GO:0045597 211 0.047
Human
single organism cell adhesion GO:0098602 179 0.047
mapk cascade GO:0000165 288 0.047
negative regulation of secretion by cell GO:1903531 52 0.046
defense response to virus GO:0051607 71 0.045
Fly
protein secretion GO:0009306 98 0.045
signal transduction by phosphorylation GO:0023014 297 0.045
system process GO:0003008 349 0.044
positive regulation of phosphorylation GO:0042327 394 0.044
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.043
Human
response to lipid GO:0033993 206 0.043
regulation of immune effector process GO:0002697 91 0.043
Fly
cytoplasmic transport GO:0016482 379 0.043
female gamete generation GO:0007292 2 0.042
t cell activation GO:0042110 99 0.042
regulation of mapk cascade GO:0043408 262 0.042
negative regulation of multicellular organismal process GO:0051241 317 0.042
hemopoiesis GO:0030097 180 0.041
Human
ras protein signal transduction GO:0007265 73 0.041
determination of adult lifespan GO:0008340 2 0.040
cellular response to oxygen containing compound GO:1901701 276 0.040
g protein coupled receptor signaling pathway GO:0007186 207 0.039
negative regulation of alpha beta t cell activation GO:0046636 3 0.038
regulation of cell cycle GO:0051726 393 0.038
regulation of cell motility GO:2000145 299 0.038
regulation of intracellular transport GO:0032386 195 0.038
leukocyte differentiation GO:0002521 98 0.037
Human
multicellular organismal aging GO:0010259 3 0.037
positive regulation of protein transport GO:0051222 135 0.037
negative regulation of cd8 positive alpha beta t cell activation GO:2001186 1 0.037
positive regulation of developmental process GO:0051094 314 0.037
Human
peptidyl tyrosine modification GO:0018212 170 0.037
negative regulation of transport GO:0051051 176 0.037
protein processing GO:0016485 226 0.037
Human Fly
negative regulation of immune system process GO:0002683 136 0.036
single organismal cell cell adhesion GO:0016337 148 0.036
positive regulation of secretion by cell GO:1903532 108 0.035
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.035
nitrogen compound transport GO:0071705 191 0.035
oogenesis GO:0048477 2 0.035
positive regulation of protein phosphorylation GO:0001934 313 0.034
positive regulation of cellular component organization GO:0051130 376 0.034
negative regulation of secretion GO:0051048 58 0.034
purine containing compound catabolic process GO:0072523 411 0.034
apoptotic signaling pathway GO:0097190 268 0.034
Human
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.034
positive regulation of catabolic process GO:0009896 310 0.034
serotonin transport GO:0006837 3 0.033
regulation of mononuclear cell proliferation GO:0032944 65 0.033
regulation of dendritic cell apoptotic process GO:2000668 4 0.033
purine nucleoside triphosphate metabolic process GO:0009144 412 0.033
cellular response to lipopolysaccharide GO:0071222 57 0.033
i kappab kinase nf kappab signaling GO:0007249 166 0.033
Human
cytokine mediated signaling pathway GO:0019221 109 0.033
cellular response to lipid GO:0071396 127 0.033
protein catabolic process GO:0030163 325 0.032
Human
regulation of erk1 and erk2 cascade GO:0070372 99 0.032
peptidyl tyrosine phosphorylation GO:0018108 170 0.032
lipid metabolic process GO:0006629 381 0.032
cation transport GO:0006812 331 0.032
actin filament based process GO:0030029 224 0.032
positive regulation of cell activation GO:0050867 81 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.032
regulation of transferase activity GO:0051338 355 0.032
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.032
regulation of eosinophil activation GO:1902566 2 0.032
positive regulation of proteolysis GO:0045862 142 0.032
Human Fly
metal ion transport GO:0030001 272 0.031
negative regulation of developmental process GO:0051093 247 0.031
regulation of cell migration GO:0030334 289 0.031
positive regulation of lymphocyte activation GO:0051251 73 0.031
mononuclear cell proliferation GO:0032943 71 0.031
negative regulation of cellular component organization GO:0051129 235 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
regulation of cell activation GO:0050865 125 0.030
chemical homeostasis GO:0048878 306 0.030
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001189 1 0.030
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.030
Human
positive regulation of leukocyte proliferation GO:0070665 48 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
response to abiotic stimulus GO:0009628 336 0.030
positive regulation of leukocyte activation GO:0002696 80 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
positive regulation of nucleotide metabolic process GO:0045981 230 0.030
ribonucleotide catabolic process GO:0009261 405 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
rho protein signal transduction GO:0007266 26 0.029
cellular response to molecule of bacterial origin GO:0071219 62 0.029
organophosphate catabolic process GO:0046434 430 0.029
nucleotide catabolic process GO:0009166 408 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
neuromuscular junction development GO:0007528 3 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
Human
purine ribonucleoside metabolic process GO:0046128 437 0.028
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
regulation of regulatory t cell differentiation GO:0045589 4 0.028
nucleoside catabolic process GO:0009164 408 0.028
positive regulation of secretion GO:0051047 116 0.027
myeloid cell differentiation GO:0030099 117 0.027
Human
cellular response to cytokine stimulus GO:0071345 181 0.027
positive regulation of locomotion GO:0040017 186 0.027
regulation of kinase activity GO:0043549 314 0.027
enzyme linked receptor protein signaling pathway GO:0007167 303 0.027
positive regulation of protein kinase activity GO:0045860 190 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
leukocyte migration GO:0050900 107 0.027
maintenance of location GO:0051235 112 0.027
regulation of endopeptidase activity GO:0052548 170 0.027
Human Fly
regulation of t cell activation GO:0050863 77 0.027
regulation of metal ion transport GO:0010959 120 0.027
positive regulation of cellular component movement GO:0051272 181 0.027
complement receptor mediated signaling pathway GO:0002430 3 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.026
interspecies interaction between organisms GO:0044419 156 0.026
purine nucleoside triphosphate catabolic process GO:0009146 392 0.026
cell type specific apoptotic process GO:0097285 125 0.026
glycosyl compound catabolic process GO:1901658 413 0.026
erk1 and erk2 cascade GO:0070371 104 0.026
purine ribonucleotide catabolic process GO:0009154 404 0.026
protein localization to organelle GO:0033365 280 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
positive regulation of cell motility GO:2000147 177 0.025
regulation of cellular response to stress GO:0080135 244 0.025
Human
single organism cellular localization GO:1902580 332 0.025
positive regulation of regulatory t cell differentiation GO:0045591 3 0.025
response to molecule of bacterial origin GO:0002237 82 0.025
regulation of calcium ion transport GO:0051924 79 0.025
negative regulation of tumor necrosis factor biosynthetic process GO:0042536 3 0.025
positive regulation of protein secretion GO:0050714 60 0.024
memory GO:0007613 3 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.024
locomotory behavior GO:0007626 1 0.024
pattern recognition receptor signaling pathway GO:0002221 48 0.024
positive regulation of transferase activity GO:0051347 227 0.024
intracellular protein transport GO:0006886 270 0.024
serotonin secretion GO:0001820 1 0.024
response to lipopolysaccharide GO:0032496 70 0.024
leukocyte proliferation GO:0070661 74 0.024
regulation of t cell proliferation GO:0042129 42 0.024
defense response to bacterium GO:0042742 63 0.024
Fly
regulation of leukocyte proliferation GO:0070663 67 0.024
negative regulation of immune response GO:0050777 40 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.023
positive regulation of cell migration GO:0030335 172 0.023
cytokine biosynthetic process GO:0042089 37 0.023
cellular lipid metabolic process GO:0044255 303 0.023
cation homeostasis GO:0055080 189 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
positive regulation of innate immune response GO:0045089 79 0.023
Fly
cell development GO:0048468 328 0.023
Fly
regulation of vesicle mediated transport GO:0060627 130 0.023
positive regulation of lymphocyte proliferation GO:0050671 46 0.023
regulation of cellular component biogenesis GO:0044087 281 0.023
regulation of protein kinase activity GO:0045859 289 0.023
protein targeting GO:0006605 187 0.023
establishment of protein localization to organelle GO:0072594 172 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
cellular cation homeostasis GO:0030003 163 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
lymphocyte proliferation GO:0046651 70 0.023
purine nucleotide catabolic process GO:0006195 405 0.022
regulation of ion transport GO:0043269 189 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
positive regulation of organelle organization GO:0010638 195 0.022
multi organism cellular process GO:0044764 156 0.022
regulation of leukocyte mediated immunity GO:0002703 38 0.022
divalent metal ion transport GO:0070838 152 0.022
positive regulation of endopeptidase activity GO:0010950 84 0.022
Human Fly
regulation of cytoplasmic transport GO:1903649 149 0.022
positive regulation of kinase activity GO:0033674 204 0.022
lipid biosynthetic process GO:0008610 177 0.022
extrinsic apoptotic signaling pathway GO:0097191 119 0.022
Human
negative regulation of cell cycle GO:0045786 193 0.022
response to wounding GO:0009611 168 0.022
compound eye development GO:0048749 1 0.022
nervous system development GO:0007399 293 0.022
regulation of gamma delta t cell activation involved in immune response GO:2001191 1 0.022
leukocyte mediated immunity GO:0002443 59 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
dephosphorylation GO:0016311 209 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
reactive nitrogen species metabolic process GO:2001057 3 0.022
regulation of apoptotic signaling pathway GO:2001233 175 0.022
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.022
Human Fly
small molecule biosynthetic process GO:0044283 157 0.022
cellular ion homeostasis GO:0006873 168 0.021
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.021
anatomical structure formation involved in morphogenesis GO:0048646 284 0.021
Fly
negative regulation of protein processing GO:0010955 142 0.021
ion homeostasis GO:0050801 230 0.021
viral life cycle GO:0019058 132 0.021
protein oligomerization GO:0051259 173 0.021
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.021
positive regulation of t cell activation GO:0050870 54 0.021
regulation of viral process GO:0050792 103 0.021
negative regulation of interleukin 12 secretion GO:2001183 1 0.021
cytokine production involved in immune response GO:0002367 27 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
regulation of cytoskeleton organization GO:0051493 177 0.021
cellular chemical homeostasis GO:0055082 180 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.021
Fly
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.021
regulation of cell cycle process GO:0010564 266 0.021
regulation of interleukin 10 secretion GO:2001179 4 0.020
regulation of lymphocyte proliferation GO:0050670 64 0.020
single organism membrane organization GO:0044802 268 0.020
innate immune response activating signal transduction GO:0002758 48 0.020
inflammatory response GO:0006954 79 0.020
regulation of cell adhesion GO:0030155 166 0.020
detection of stimulus GO:0051606 85 0.020
calcium ion transport GO:0006816 147 0.020
mitotic cell cycle GO:0000278 326 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.020
Fly
organophosphate biosynthetic process GO:0090407 163 0.020
cellular homeostasis GO:0019725 196 0.020
negative regulation of protein transport GO:0051224 75 0.020
myeloid leukocyte differentiation GO:0002573 60 0.020
Human
dendritic cell apoptotic process GO:0097048 4 0.020
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
Human Fly
negative regulation of protein secretion GO:0050709 29 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
Fly
regulation of purine nucleotide catabolic process GO:0033121 205 0.020
segmentation GO:0035282 4 0.020
cellular metal ion homeostasis GO:0006875 146 0.020
adaptive immune response GO:0002250 49 0.020
cellular protein catabolic process GO:0044257 261 0.020
Human
negative regulation of serotonin secretion GO:0014063 1 0.020
positive regulation of nucleoside metabolic process GO:0045979 186 0.020
neurological system process GO:0050877 163 0.020
detection of muramyl dipeptide GO:0032498 1 0.020
oxidation reduction process GO:0055114 396 0.019
gtp metabolic process GO:0046039 239 0.019
positive regulation of nucleotide catabolic process GO:0030813 185 0.019
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.019
Fly
negative regulation of protein modification process GO:0031400 200 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
positive regulation of cytokine secretion GO:0050715 42 0.019
nuclear transport GO:0051169 179 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
Human
taxis GO:0042330 157 0.019
regulation of protein maturation GO:1903317 150 0.019
positive regulation of peptidase activity GO:0010952 88 0.019
Human Fly
membrane organization GO:0061024 292 0.019
activation of innate immune response GO:0002218 55 0.019
regulation of small gtpase mediated signal transduction GO:0051056 156 0.019
alcohol metabolic process GO:0006066 114 0.019
nucleocytoplasmic transport GO:0006913 176 0.018
regulation of gtp catabolic process GO:0033124 180 0.018
actin cytoskeleton organization GO:0030036 207 0.018
positive regulation of leukocyte differentiation GO:1902107 37 0.018
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.018
cellular component morphogenesis GO:0032989 314 0.018
regulation of protein catabolic process GO:0042176 155 0.018
negative regulation of protein maturation GO:1903318 142 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
anion transport GO:0006820 161 0.018
spermatid differentiation GO:0048515 4 0.018
Fly
sequestering of metal ion GO:0051238 24 0.018
peripheral nervous system development GO:0007422 2 0.018
Fly
regulation of dna metabolic process GO:0051052 153 0.018
response to organic cyclic compound GO:0014070 204 0.018
viral process GO:0016032 146 0.018
regeneration GO:0031099 4 0.018
activation of cysteine type endopeptidase activity GO:0097202 57 0.018
Human Fly
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.018
cellular response to biotic stimulus GO:0071216 71 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.018
response to fungus GO:0009620 4 0.018
endocytosis GO:0006897 159 0.018
osteoclast development GO:0036035 2 0.018
positive regulation of t cell proliferation GO:0042102 33 0.018
regulation of leukocyte differentiation GO:1902105 61 0.018
Human
negative regulation of cell differentiation GO:0045596 171 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
chemotaxis GO:0006935 157 0.018
positive regulation of t cell tolerance induction GO:0002666 2 0.018
carbohydrate metabolic process GO:0005975 207 0.018
divalent inorganic cation transport GO:0072511 158 0.018
mitotic cell cycle process GO:1903047 286 0.018
regulation of protein processing GO:0070613 150 0.018
lymphocyte mediated immunity GO:0002449 48 0.017
cell activation involved in immune response GO:0002263 30 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
negative regulation of multi organism process GO:0043901 92 0.017
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.017
positive regulation of immune effector process GO:0002699 40 0.017
Fly
stress activated protein kinase signaling cascade GO:0031098 94 0.017
cardiac muscle cell contraction GO:0086003 4 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
rhythmic behavior GO:0007622 2 0.017
positive regulation of intracellular transport GO:0032388 104 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.017
regulation of cytokine biosynthetic process GO:0042035 35 0.017
regulation of defense response to virus GO:0050688 33 0.017
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
Human
cell morphogenesis GO:0000902 296 0.017
positive regulation of mononuclear cell proliferation GO:0032946 47 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
Human
oocyte development GO:0048599 1 0.017
detection of chemical stimulus GO:0009593 55 0.017
negative regulation of cytokine production involved in immune response GO:0002719 13 0.017
regulation of response to wounding GO:1903034 101 0.017
zymogen activation GO:0031638 70 0.017
Human Fly
negative regulation of cytokine production GO:0001818 82 0.017
regulation of phagocytosis engulfment GO:0060099 2 0.016
cell chemotaxis GO:0060326 112 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.016
metal ion homeostasis GO:0055065 169 0.016
organic hydroxy compound transport GO:0015850 63 0.016
oocyte differentiation GO:0009994 2 0.016
regulation of homeostatic process GO:0032844 121 0.016
circadian behavior GO:0048512 2 0.016
positive regulation of defense response GO:0031349 87 0.016
Fly
circulatory system development GO:0072359 262 0.016
negative regulation of interferon beta production GO:0032688 4 0.016
blood vessel development GO:0001568 172 0.016
protein localization to nucleus GO:0034504 136 0.016
granulocyte migration GO:0097530 40 0.016
sequestering of calcium ion GO:0051208 17 0.016
regulation of gamma delta t cell activation GO:0046643 1 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
chromatin organization GO:0006325 351 0.016
fc receptor mediated inhibitory signaling pathway GO:0002774 2 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
Human
positive regulation of gamma delta t cell activation GO:0046645 1 0.016
regulation of cytokine production involved in immune response GO:0002718 22 0.016
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.016
epithelium development GO:0060429 227 0.016
Human
negative regulation of phosphorylation GO:0042326 174 0.016
spermatid development GO:0007286 4 0.016
Fly
cardiovascular system development GO:0072358 262 0.016
cell killing GO:0001906 34 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
gtp catabolic process GO:0006184 237 0.015
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.015
negative regulation of dendritic cell differentiation GO:2001199 2 0.015
actin filament organization GO:0007015 128 0.015
calcium ion homeostasis GO:0055074 122 0.015
blastoderm segmentation GO:0007350 2 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
regulation of ras protein signal transduction GO:0046578 155 0.015
actin mediated cell contraction GO:0070252 12 0.015
covalent chromatin modification GO:0016569 254 0.015
cellular response to external stimulus GO:0071496 111 0.015
transmembrane transport GO:0055085 399 0.015
protein import GO:0017038 130 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
positive regulation of astrocyte chemotaxis GO:2000464 1 0.015
single organism nuclear import GO:1902593 104 0.015
interferon gamma production GO:0032609 39 0.015
negative regulation of immune effector process GO:0002698 38 0.015
positive regulation of chemotaxis GO:0050921 57 0.015
glial cell migration GO:0008347 4 0.015
positive regulation of gtp catabolic process GO:0033126 166 0.015
developmental programmed cell death GO:0010623 3 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.015
regulation of actin filament based process GO:0032970 141 0.015
adult locomotory behavior GO:0008344 1 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
protein ubiquitination GO:0016567 314 0.014
regulation of peptidyl serine phosphorylation of stat protein GO:0033139 3 0.014
regulation of protein targeting GO:1903533 91 0.014
single organism carbohydrate metabolic process GO:0044723 193 0.014
myoblast fusion GO:0007520 1 0.014
regulation of endocytosis GO:0030100 72 0.014
leukocyte activation involved in immune response GO:0002366 30 0.014
interferon beta secretion GO:0035546 1 0.014
positive regulation of map kinase activity GO:0043406 80 0.014
protein import into nucleus GO:0006606 104 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
negative regulation of proteolysis GO:0045861 132 0.014
regulation of response to biotic stimulus GO:0002831 55 0.014
Fly
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.014
regulation of interferon beta production GO:0032648 22 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
cell fate determination GO:0001709 3 0.014
response to growth factor GO:0070848 205 0.014
positive regulation of cytolysis GO:0045919 3 0.014
actin filament based movement GO:0030048 17 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.014
peptide transport GO:0015833 74 0.014
jak stat cascade GO:0007259 46 0.014
regulation of chemotaxis GO:0050920 74 0.014
regulation of myeloid cell differentiation GO:0045637 81 0.014
Human
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.014
positive regulation of synaptic transmission GO:0050806 4 0.014
phospholipid metabolic process GO:0006644 99 0.014
glycoprotein metabolic process GO:0009100 110 0.014
regulation of lymphocyte mediated immunity GO:0002706 33 0.014
regulation of gtpase activity GO:0043087 180 0.014

CASP5 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.029
Human
cancer DOID:162 167 0.027
Human
organ system cancer DOID:0050686 164 0.025
Human
disease of metabolism DOID:0014667 295 0.024
musculoskeletal system disease DOID:17 223 0.023
sensory system disease DOID:0050155 203 0.022
nervous system disease DOID:863 431 0.022
immune system disease DOID:2914 155 0.018
Human
inherited metabolic disorder DOID:655 242 0.018
connective tissue disease DOID:65 109 0.014
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014