Homo sapiens

94 known processes

CASP2

caspase 2, apoptosis-related cysteine peptidase

(Aliases: NEDD2,NEDD-2,ICH1,CASP-2)

CASP2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
signal transduction involved in mitotic cell cycle checkpoint GO:0072413 13 0.963
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.951
Fly
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.935
Fly
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 9 0.900
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.868
positive regulation of peptidase activity GO:0010952 88 0.866
Human Fly
mitotic g1 dna damage checkpoint GO:0031571 17 0.862
positive regulation of apoptotic signaling pathway GO:2001235 70 0.861
Mouse Fly
zymogen activation GO:0031638 70 0.856
Human Fly
regulation of peptidase activity GO:0052547 180 0.846
Human Fly
mitotic g1 s transition checkpoint GO:0044819 17 0.829
g1 dna damage checkpoint GO:0044783 18 0.815
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.807
cell cycle arrest GO:0007050 71 0.806
activation of cysteine type endopeptidase activity GO:0097202 57 0.804
Human Fly
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 10 0.771
positive regulation of cell death GO:0010942 263 0.763
mitotic cell cycle phase transition GO:0044772 162 0.755
positive regulation of proteolysis GO:0045862 142 0.748
Human Fly
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.722
regulation of cell cycle arrest GO:0071156 36 0.717
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.712
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 10 0.706
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.704
Human Fly
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.703
g1 s transition of mitotic cell cycle GO:0000082 78 0.699
signal transduction involved in dna damage checkpoint GO:0072422 15 0.681
negative regulation of cell cycle g1 s phase transition GO:1902807 29 0.672
regulation of proteolysis GO:0030162 293 0.664
Human Fly
positive regulation of endopeptidase activity GO:0010950 84 0.663
Human Fly
dna damage checkpoint GO:0000077 68 0.659
apoptotic signaling pathway GO:0097190 268 0.658
Human Mouse Fly
protein processing GO:0016485 226 0.612
cellular response to mechanical stimulus GO:0071260 39 0.588
dna integrity checkpoint GO:0031570 71 0.584
positive regulation of hydrolase activity GO:0051345 331 0.582
Human Fly
positive regulation of cell cycle GO:0045787 140 0.575
negative regulation of cell cycle process GO:0010948 121 0.570
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.569
regulation of apoptotic signaling pathway GO:2001233 175 0.558
Mouse Fly
cell cycle phase transition GO:0044770 173 0.540
positive regulation of apoptotic process GO:0043065 246 0.529
regulation of cell cycle process GO:0010564 266 0.526
regulation of mitotic cell cycle phase transition GO:1901990 118 0.517
regulation of endopeptidase activity GO:0052548 170 0.506
Human Fly
mitotic cell cycle GO:0000278 326 0.503
positive regulation of cell cycle process GO:0090068 106 0.489
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.475
cell cycle g1 s phase transition GO:0044843 80 0.470
cell cycle checkpoint GO:0000075 117 0.465
negative regulation of cell cycle GO:0045786 193 0.452
regulation of mitotic cell cycle GO:0007346 189 0.398
regulation of cell cycle g1 s phase transition GO:1902806 42 0.394
negative regulation of mitotic cell cycle GO:0045930 102 0.360
cellular response to dna damage stimulus GO:0006974 379 0.359
regulation of cell cycle GO:0051726 393 0.349
cellular response to abiotic stimulus GO:0071214 117 0.274
protein maturation GO:0051604 233 0.258
mitotic cell cycle checkpoint GO:0007093 68 0.224
signal transduction by p53 class mediator GO:0072331 72 0.218
regulation of cysteine type endopeptidase activity GO:2000116 127 0.202
Human Fly
mitotic dna integrity checkpoint GO:0044774 30 0.197
determination of adult lifespan GO:0008340 2 0.180
Worm Fly
negative regulation of cell cycle phase transition GO:1901988 89 0.168
extrinsic apoptotic signaling pathway GO:0097191 119 0.163
Human Mouse
positive regulation of cell cycle arrest GO:0071158 23 0.153
regulation of cell cycle phase transition GO:1901987 126 0.145
negative regulation of apoptotic process GO:0043066 316 0.136
Human
negative regulation of cell death GO:0060548 345 0.133
Human Fly
post embryonic development GO:0009791 2 0.131
Fly
multicellular organismal aging GO:0010259 3 0.120
Worm Fly
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.114
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.106
nervous system development GO:0007399 293 0.103
Rat Fly
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.097
mitotic cell cycle process GO:1903047 286 0.084
regulation of cellular ketone metabolic process GO:0010565 50 0.077
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.075
regulation of cellular amino acid metabolic process GO:0006521 6 0.073
cellular amino acid metabolic process GO:0006520 116 0.072
ribonucleoside catabolic process GO:0042454 406 0.068
positive regulation of protein phosphorylation GO:0001934 313 0.067
regulation of cell differentiation GO:0045595 393 0.065
Human Fly
cation transport GO:0006812 331 0.062
ribonucleoside triphosphate metabolic process GO:0009199 412 0.061
small gtpase mediated signal transduction GO:0007264 78 0.061
vesicle mediated transport GO:0016192 371 0.061
Worm
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.058
regulation of cellular amine metabolic process GO:0033238 11 0.057
ras protein signal transduction GO:0007265 73 0.056
membrane organization GO:0061024 292 0.055
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.054
positive regulation of cell differentiation GO:0045597 211 0.054
Human Fly
response to radiation GO:0009314 151 0.053
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.053
Human
chemical homeostasis GO:0048878 306 0.052
amine metabolic process GO:0009308 44 0.051
immune system development GO:0002520 195 0.051
Human
cell development GO:0048468 328 0.050
Mouse Fly
positive regulation of cell proliferation GO:0008284 301 0.050
purine nucleoside triphosphate metabolic process GO:0009144 412 0.050
nucleotide catabolic process GO:0009166 408 0.049
protein catabolic process GO:0030163 325 0.049
Human Worm
organophosphate catabolic process GO:0046434 430 0.049
cellular ketone metabolic process GO:0042180 80 0.048
regulation of kinase activity GO:0043549 314 0.048
female gamete generation GO:0007292 2 0.047
Fly
dna repair GO:0006281 198 0.047
response to abiotic stimulus GO:0009628 336 0.046
purine containing compound catabolic process GO:0072523 411 0.046
rna processing GO:0006396 255 0.046
regulation of transferase activity GO:0051338 355 0.046
positive regulation of cellular component organization GO:0051130 376 0.046
response to biotic stimulus GO:0009607 276 0.045
Fly
negative regulation of cell proliferation GO:0008285 228 0.043
Fly
cellular amine metabolic process GO:0044106 41 0.043
purine ribonucleoside metabolic process GO:0046128 437 0.043
hemopoiesis GO:0030097 180 0.043
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.042
Human
cell morphogenesis GO:0000902 296 0.041
Fly
purine ribonucleoside catabolic process GO:0046130 398 0.041
purine ribonucleotide catabolic process GO:0009154 404 0.041
nucleoside catabolic process GO:0009164 408 0.041
negative regulation of protein metabolic process GO:0051248 391 0.041
nucleoside triphosphate catabolic process GO:0009143 394 0.040
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.040
Fly
regeneration GO:0031099 4 0.039
protein modification by small protein conjugation GO:0032446 342 0.038
gtp catabolic process GO:0006184 237 0.038
cellular component morphogenesis GO:0032989 314 0.038
Fly
generation of neurons GO:0048699 152 0.038
Fly
nucleoside triphosphate metabolic process GO:0009141 422 0.037
lipid metabolic process GO:0006629 381 0.036
cellular response to endogenous stimulus GO:0071495 336 0.035
negative regulation of phosphorus metabolic process GO:0010563 267 0.035
rho protein signal transduction GO:0007266 26 0.035
immune response GO:0006955 307 0.035
Fly
immune effector process GO:0002252 159 0.035
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.034
negative regulation of catalytic activity GO:0043086 335 0.034
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
protein localization to organelle GO:0033365 280 0.034
cell activation GO:0001775 213 0.034
purine nucleoside triphosphate catabolic process GO:0009146 392 0.034
regulation of anatomical structure morphogenesis GO:0022603 286 0.034
Fly
compound eye development GO:0048749 1 0.033
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
modification dependent macromolecule catabolic process GO:0043632 212 0.033
response to oxygen containing compound GO:1901700 369 0.033
gtp metabolic process GO:0046039 239 0.033
covalent chromatin modification GO:0016569 254 0.033
metal ion transport GO:0030001 272 0.032
actin filament based process GO:0030029 224 0.032
response to organonitrogen compound GO:0010243 156 0.032
response to nitrogen compound GO:1901698 184 0.031
protein ubiquitination GO:0016567 314 0.031
positive regulation of immune system process GO:0002684 283 0.031
Human Fly
single organism membrane organization GO:0044802 268 0.031
cellular macromolecular complex assembly GO:0034622 324 0.031
regulation of small gtpase mediated signal transduction GO:0051056 156 0.030
negative regulation of programmed cell death GO:0043069 321 0.030
Human Fly
regulation of cell development GO:0060284 161 0.030
Fly
cell projection organization GO:0030030 252 0.030
Fly
cytoplasmic transport GO:0016482 379 0.029
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
cellular lipid metabolic process GO:0044255 303 0.028
regulation of protein kinase activity GO:0045859 289 0.028
response to external biotic stimulus GO:0043207 261 0.028
Fly
positive regulation of developmental process GO:0051094 314 0.028
Human Fly
positive regulation of organelle organization GO:0010638 195 0.028
ubiquitin dependent protein catabolic process GO:0006511 206 0.028
positive regulation of programmed cell death GO:0043068 249 0.028
regulation of cellular component movement GO:0051270 334 0.028
cellular response to oxygen containing compound GO:1901701 276 0.027
regulation of protein processing GO:0070613 150 0.027
system process GO:0003008 349 0.027
embryo development GO:0009790 123 0.027
Worm Fly
circulatory system development GO:0072359 262 0.027
negative regulation of developmental process GO:0051093 247 0.027
cellular response to organonitrogen compound GO:0071417 124 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
positive regulation of phosphorylation GO:0042327 394 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
cellular protein catabolic process GO:0044257 261 0.026
Human
ribonucleotide catabolic process GO:0009261 405 0.026
nuclear transport GO:0051169 179 0.026
myeloid cell differentiation GO:0030099 117 0.026
Human
regulation of protein catabolic process GO:0042176 155 0.026
guanosine containing compound catabolic process GO:1901069 239 0.026
cellular response to nitrogen compound GO:1901699 144 0.026
regulation of cell morphogenesis GO:0022604 153 0.026
defense response GO:0006952 315 0.025
Fly
regulation of immune response GO:0050776 201 0.025
Fly
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.025
negative regulation of transferase activity GO:0051348 124 0.025
neuromuscular junction development GO:0007528 3 0.025
modification dependent protein catabolic process GO:0019941 209 0.025
positive regulation of immune response GO:0050778 159 0.025
Fly
response to other organism GO:0051707 261 0.025
Fly
response to cytokine GO:0034097 232 0.025
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.025
cell fate determination GO:0001709 3 0.024
macromolecule methylation GO:0043414 97 0.024
spermatid development GO:0007286 4 0.024
Fly
glycosyl compound catabolic process GO:1901658 413 0.024
ion homeostasis GO:0050801 230 0.024
response to fungus GO:0009620 4 0.024
spermatid differentiation GO:0048515 4 0.023
Fly
leukocyte activation GO:0045321 164 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
regulation of protein serine threonine kinase activity GO:0071900 179 0.023
guanosine containing compound metabolic process GO:1901068 244 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
neuron development GO:0048666 113 0.023
Fly
cellular homeostasis GO:0019725 196 0.022
innate immune response GO:0045087 178 0.022
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.022
epithelial cell differentiation GO:0030855 141 0.022
Human
peripheral nervous system development GO:0007422 2 0.022
Fly
developmental programmed cell death GO:0010623 3 0.022
Mouse Fly
negative regulation of protein modification process GO:0031400 200 0.022
mapk cascade GO:0000165 288 0.021
nucleocytoplasmic transport GO:0006913 176 0.021
regulation of gtpase activity GO:0043087 180 0.021
oogenesis GO:0048477 2 0.021
Fly
positive regulation of cellular catabolic process GO:0031331 284 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
regulation of nucleoside metabolic process GO:0009118 209 0.021
regulation of growth GO:0040008 165 0.021
positive regulation of kinase activity GO:0033674 204 0.021
calcium ion transport GO:0006816 147 0.021
viral process GO:0016032 146 0.021
regulation of cell growth GO:0001558 135 0.021
growth GO:0040007 202 0.021
regulation of cell motility GO:2000145 299 0.021
cellular macromolecule catabolic process GO:0044265 380 0.020
Human
positive regulation of catabolic process GO:0009896 310 0.020
cell growth GO:0016049 160 0.020
tissue migration GO:0090130 119 0.020
divalent inorganic cation homeostasis GO:0072507 136 0.020
enzyme linked receptor protein signaling pathway GO:0007167 303 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
methylation GO:0032259 106 0.019
divalent inorganic cation transport GO:0072511 158 0.019
biological adhesion GO:0022610 331 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.019
cation homeostasis GO:0055080 189 0.019
single organism cellular localization GO:1902580 332 0.019
epithelial cell proliferation GO:0050673 128 0.018
leukocyte differentiation GO:0002521 98 0.018
Human
associative learning GO:0008306 1 0.018
response to wounding GO:0009611 168 0.018
maintenance of location GO:0051235 112 0.018
dephosphorylation GO:0016311 209 0.018
mitochondrion organization GO:0007005 156 0.018
cellular response to organic cyclic compound GO:0071407 127 0.018
regulation of protein ubiquitination GO:0031396 95 0.018
lymphocyte activation GO:0046649 133 0.018
actin cytoskeleton organization GO:0030036 207 0.018
negative regulation of immune system process GO:0002683 136 0.018
cytokine production GO:0001816 247 0.018
reproductive process GO:0022414 106 0.017
Mouse Rat Fly
regulation of ras protein signal transduction GO:0046578 155 0.017
regulation of protein complex assembly GO:0043254 147 0.017
response to ionizing radiation GO:0010212 65 0.017
regulation of intracellular transport GO:0032386 195 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
secretion by cell GO:0032940 226 0.017
regulation of secretion by cell GO:1903530 177 0.017
embryonic epithelial tube formation GO:0001838 4 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.017
Human
dna replication GO:0006260 116 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
neurogenesis GO:0022008 169 0.017
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
protein targeting GO:0006605 187 0.017
autophagic cell death GO:0048102 3 0.016
Fly
oxidation reduction process GO:0055114 396 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
locomotory behavior GO:0007626 1 0.016
regulation of cell migration GO:0030334 289 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
cellular cation homeostasis GO:0030003 163 0.016
cellular ion homeostasis GO:0006873 168 0.016
ion transmembrane transport GO:0034220 338 0.016
rna splicing GO:0008380 131 0.016
cell part morphogenesis GO:0032990 137 0.016
Fly
regulation of cellular response to stress GO:0080135 244 0.016
Human
somatic stem cell maintenance GO:0035019 4 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
tissue regeneration GO:0042246 3 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.016
Human
single organism carbohydrate metabolic process GO:0044723 193 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
Human
regulation of nucleotide catabolic process GO:0030811 205 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
regulation of protein transport GO:0051223 213 0.016
carbohydrate metabolic process GO:0005975 207 0.015
central nervous system development GO:0007417 123 0.015
Rat Fly
proteasomal protein catabolic process GO:0010498 176 0.015
regulation of epithelial cell proliferation GO:0050678 113 0.015
positive regulation of cell migration GO:0030335 172 0.015
interspecies interaction between organisms GO:0044419 156 0.015
divalent metal ion transport GO:0070838 152 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
response to tumor necrosis factor GO:0034612 76 0.015
Human
negative regulation of protein kinase activity GO:0006469 98 0.015
single organism reproductive process GO:0044702 98 0.015
Mouse Rat Fly
negative regulation of transport GO:0051051 176 0.015
metal ion homeostasis GO:0055065 169 0.015
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.015
negative regulation of catabolic process GO:0009895 104 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.014
neuron differentiation GO:0030182 138 0.014
Fly
positive regulation of gtpase activity GO:0043547 166 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
protein dephosphorylation GO:0006470 81 0.014
epithelium migration GO:0090132 119 0.014
cell projection morphogenesis GO:0048858 129 0.014
Fly
intracellular protein transport GO:0006886 270 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
cardiovascular system development GO:0072358 262 0.014
negative regulation of proteolysis GO:0045861 132 0.014
response to drug GO:0042493 81 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
positive regulation of transferase activity GO:0051347 227 0.014
response to organic cyclic compound GO:0014070 204 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
Human
anatomical structure homeostasis GO:0060249 100 0.014
rna interference GO:0016246 4 0.014
nitrogen compound transport GO:0071705 191 0.014
cell adhesion GO:0007155 325 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.014
Human
negative regulation of protein maturation GO:1903318 142 0.014
regulation of protein localization GO:0032880 296 0.014
cellular chemical homeostasis GO:0055082 180 0.014
epithelium development GO:0060429 227 0.014
Human
cellular metal ion homeostasis GO:0006875 146 0.014
ameboidal type cell migration GO:0001667 135 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
ossification GO:0001503 121 0.013
neural tube formation GO:0001841 3 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
calcium ion homeostasis GO:0055074 122 0.013
memory GO:0007613 3 0.013
adult locomotory behavior GO:0008344 1 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
secretion GO:0046903 254 0.013
epithelial cell migration GO:0010631 119 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
regulation of protein maturation GO:1903317 150 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
double strand break repair GO:0006302 101 0.013
chromatin organization GO:0006325 351 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
endocytosis GO:0006897 159 0.013
Worm
sequestering of calcium ion GO:0051208 17 0.013
cellular response to external stimulus GO:0071496 111 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
regulation of dna metabolic process GO:0051052 153 0.013
cytosolic calcium ion homeostasis GO:0051480 89 0.013
oocyte development GO:0048599 1 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
chemotaxis GO:0006935 157 0.013
engulfment of apoptotic cell GO:0043652 2 0.013
Worm
cell matrix adhesion GO:0007160 85 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
Fly
cell division GO:0051301 168 0.013
response to growth factor GO:0070848 205 0.013
protein autophosphorylation GO:0046777 123 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
regulation of leukocyte differentiation GO:1902105 61 0.012
Human
neurological system process GO:0050877 163 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
negative regulation of cell growth GO:0030308 83 0.012
endomembrane system organization GO:0010256 196 0.012
regulation of mapk cascade GO:0043408 262 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
cytokinesis GO:0000910 96 0.012
protein localization to nucleus GO:0034504 136 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
humoral immune response GO:0006959 49 0.012
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.012
positive regulation of epithelial cell proliferation GO:0050679 65 0.012
microtubule based process GO:0007017 210 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
neural crest cell development GO:0014032 3 0.012
regulation of response to external stimulus GO:0032101 222 0.012
Fly
regulation of response to dna damage stimulus GO:2001020 94 0.012
Human
amide transport GO:0042886 76 0.012
regulation of homeostatic process GO:0032844 121 0.012
segmentation GO:0035282 4 0.012
plasma membrane organization GO:0007009 115 0.012
response to axon injury GO:0048678 1 0.012
monovalent inorganic cation transport GO:0015672 128 0.012
response to hormone GO:0009725 175 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
myeloid cell homeostasis GO:0002262 34 0.012
Human
chromatin modification GO:0016568 298 0.011
actin filament based movement GO:0030048 17 0.011
cell chemotaxis GO:0060326 112 0.011
regulation of cellular component size GO:0032535 82 0.011
cell type specific apoptotic process GO:0097285 125 0.011
Rat Fly
protein homooligomerization GO:0051260 100 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
primary neural tube formation GO:0014020 3 0.011
negative regulation of apoptotic signaling pathway GO:2001234 97 0.011
wound healing GO:0042060 115 0.011
taxis GO:0042330 157 0.011
axon regeneration GO:0031103 1 0.011
atp metabolic process GO:0046034 176 0.011
sulfur compound metabolic process GO:0006790 101 0.011
regulation of dephosphorylation GO:0035303 96 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
response to inorganic substance GO:0010035 127 0.011
erk1 and erk2 cascade GO:0070371 104 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
histone lysine methylation GO:0034968 50 0.011
positive regulation of cell motility GO:2000147 177 0.011
regulation of vasculature development GO:1901342 97 0.011
multi organism cellular process GO:0044764 156 0.011
oocyte differentiation GO:0009994 2 0.011
organelle assembly GO:0070925 176 0.011
positive regulation of meiotic cell cycle GO:0051446 2 0.011
myeloid leukocyte differentiation GO:0002573 60 0.011
Human
positive regulation of locomotion GO:0040017 186 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
positive regulation of cell adhesion GO:0045785 84 0.011
regulation of cell adhesion GO:0030155 166 0.011
neural tube closure GO:0001843 3 0.011
regulation of cell activation GO:0050865 125 0.011
translation GO:0006412 132 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.011
organelle fission GO:0048285 149 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
Human
cell cell signaling GO:0007267 155 0.011
regulation of leukocyte activation GO:0002694 115 0.011
negative regulation of cellular component movement GO:0051271 106 0.011
limbic system development GO:0021761 3 0.011
peptidyl serine modification GO:0018209 106 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
epidermis morphogenesis GO:0048730 3 0.010
protein import GO:0017038 130 0.010
peptidyl serine phosphorylation GO:0018105 101 0.010
signal transduction in response to dna damage GO:0042770 57 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.010
cofactor metabolic process GO:0051186 87 0.010
tube closure GO:0060606 3 0.010
regulation of map kinase activity GO:0043405 108 0.010
regulation of binding GO:0051098 111 0.010
jak stat cascade GO:0007259 46 0.010
t cell differentiation in thymus GO:0033077 4 0.010
ornithine metabolic process GO:0006591 3 0.010
regulation of body fluid levels GO:0050878 99 0.010

CASP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.045
Human
cancer DOID:162 167 0.037
Human
organ system cancer DOID:0050686 164 0.037
Human
immune system disease DOID:2914 155 0.034
Human
musculoskeletal system disease DOID:17 223 0.027
disease of metabolism DOID:0014667 295 0.023
bone disease DOID:0080001 88 0.018
connective tissue disease DOID:65 109 0.018
sensory system disease DOID:0050155 203 0.016
nervous system disease DOID:863 431 0.016
acquired metabolic disease DOID:0060158 58 0.015
gastrointestinal system cancer DOID:3119 52 0.015
Human
eye and adnexa disease DOID:1492 150 0.012
eye disease DOID:5614 149 0.010