Homo sapiens

0 known processes

SLC4A5

solute carrier family 4, sodium bicarbonate cotransporter, member 5

(Aliases: NBC4,MGC129662)

SLC4A5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.064
locomotory behavior GO:0007626 1 0.044
cellular amino acid metabolic process GO:0006520 116 0.037
determination of adult lifespan GO:0008340 2 0.037
multicellular organismal aging GO:0010259 3 0.037
amine metabolic process GO:0009308 44 0.035
female gamete generation GO:0007292 2 0.033
oogenesis GO:0048477 2 0.030
small gtpase mediated signal transduction GO:0007264 78 0.029
nucleoside phosphate catabolic process GO:1901292 412 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
purine ribonucleotide catabolic process GO:0009154 404 0.028
purine ribonucleoside metabolic process GO:0046128 437 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.028
system process GO:0003008 349 0.028
Mouse
cellular ketone metabolic process GO:0042180 80 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
positive regulation of catabolic process GO:0009896 310 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
ras protein signal transduction GO:0007265 73 0.027
cellular macromolecule catabolic process GO:0044265 380 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
ribonucleotide catabolic process GO:0009261 405 0.026
cellular component morphogenesis GO:0032989 314 0.026
purine containing compound catabolic process GO:0072523 411 0.026
cell adhesion GO:0007155 325 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
nucleoside triphosphate metabolic process GO:0009141 422 0.025
regulation of cell cycle GO:0051726 393 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
negative regulation of cellular protein metabolic process GO:0032269 353 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
chemical homeostasis GO:0048878 306 0.024
Human
nucleotide catabolic process GO:0009166 408 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
mitotic cell cycle GO:0000278 326 0.023
cell morphogenesis GO:0000902 296 0.023
neuromuscular junction development GO:0007528 3 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
organophosphate catabolic process GO:0046434 430 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
positive regulation of apoptotic process GO:0043065 246 0.022
regulation of cellular ketone metabolic process GO:0010565 50 0.022
cell projection organization GO:0030030 252 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
regulation of kinase activity GO:0043549 314 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
biological adhesion GO:0022610 331 0.022
protein catabolic process GO:0030163 325 0.021
cellular amine metabolic process GO:0044106 41 0.021
response to abiotic stimulus GO:0009628 336 0.021
regeneration GO:0031099 4 0.021
regulation of transferase activity GO:0051338 355 0.021
adult locomotory behavior GO:0008344 1 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
immune response GO:0006955 307 0.020
protein localization to organelle GO:0033365 280 0.020
mating GO:0007618 1 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
neuroblast proliferation GO:0007405 4 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.019
chromatin organization GO:0006325 351 0.019
mitotic cell cycle process GO:1903047 286 0.019
positive regulation of cell death GO:0010942 263 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
negative regulation of protein modification process GO:0031400 200 0.019
segmentation GO:0035282 4 0.019
regulation of cellular response to stress GO:0080135 244 0.019
memory GO:0007613 3 0.019
cellular protein catabolic process GO:0044257 261 0.019
nervous system development GO:0007399 293 0.019
regulation of cell cycle process GO:0010564 266 0.019
actin filament based process GO:0030029 224 0.019
dephosphorylation GO:0016311 209 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
regulation of mapk cascade GO:0043408 262 0.018
enzyme linked receptor protein signaling pathway GO:0007167 303 0.018
regulation of protein kinase activity GO:0045859 289 0.018
nucleoside catabolic process GO:0009164 408 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
rho protein signal transduction GO:0007266 26 0.018
response to oxygen containing compound GO:1901700 369 0.018
histone modification GO:0016570 251 0.018
cytoplasmic transport GO:0016482 379 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
rhythmic behavior GO:0007622 2 0.017
oocyte development GO:0048599 1 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
regulation of proteolysis GO:0030162 293 0.017
mitochondrion organization GO:0007005 156 0.017
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
spermatid differentiation GO:0048515 4 0.017
neurological system process GO:0050877 163 0.016
single organism cellular localization GO:1902580 332 0.016
Mouse
circadian behavior GO:0048512 2 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
regulation of mitotic cell cycle GO:0007346 189 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
blastoderm segmentation GO:0007350 2 0.016
mapk cascade GO:0000165 288 0.016
protein maturation GO:0051604 233 0.016
maintenance of location GO:0051235 112 0.016
regulation of cellular component movement GO:0051270 334 0.016
oxidation reduction process GO:0055114 396 0.016
cell development GO:0048468 328 0.016
Mouse
growth GO:0040007 202 0.016
lipid metabolic process GO:0006629 381 0.016
hindbrain development GO:0030902 3 0.016
response to cytokine GO:0034097 232 0.016
carbohydrate metabolic process GO:0005975 207 0.016
ion transmembrane transport GO:0034220 338 0.016
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
positive regulation of hormone biosynthetic process GO:0046886 4 0.016
morphogenesis of embryonic epithelium GO:0016331 4 0.016
metal ion transport GO:0030001 272 0.016
Human
negative regulation of cell death GO:0060548 345 0.016
protein processing GO:0016485 226 0.016
positive regulation of developmental process GO:0051094 314 0.016
microtubule based process GO:0007017 210 0.016
defense response GO:0006952 315 0.016
response to external biotic stimulus GO:0043207 261 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
transmembrane transport GO:0055085 399 0.015
Human
apoptotic signaling pathway GO:0097190 268 0.015
oocyte differentiation GO:0009994 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
negative regulation of cellular amine metabolic process GO:0033239 3 0.015
chromatin modification GO:0016568 298 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
sleep GO:0030431 2 0.015
intracellular protein transport GO:0006886 270 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
anterior posterior axis specification GO:0009948 2 0.015
sensory perception GO:0007600 103 0.015
photoreceptor cell differentiation GO:0046530 2 0.015
proteasomal protein catabolic process GO:0010498 176 0.014
negative regulation of cell cycle GO:0045786 193 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
Human
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.014
protein ubiquitination GO:0016567 314 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
response to biotic stimulus GO:0009607 276 0.014
membrane organization GO:0061024 292 0.014
gtp metabolic process GO:0046039 239 0.014
cell growth GO:0016049 160 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
innate immune response GO:0045087 178 0.014
protein targeting GO:0006605 187 0.014
spermatid development GO:0007286 4 0.014
gtp catabolic process GO:0006184 237 0.014
cellular protein complex assembly GO:0043623 188 0.014
cellular chemical homeostasis GO:0055082 180 0.014
Human
negative regulation of cellular component organization GO:0051129 235 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
positive regulation of transport GO:0051050 336 0.014
regulation of protein localization GO:0032880 296 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
endomembrane system organization GO:0010256 196 0.014
regulation of response to external stimulus GO:0032101 222 0.014
regulation of protein catabolic process GO:0042176 155 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
response to other organism GO:0051707 261 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
covalent chromatin modification GO:0016569 254 0.014
cation transmembrane transport GO:0098655 238 0.014
Human
regulation of cell differentiation GO:0045595 393 0.014
peripheral nervous system development GO:0007422 2 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
negative regulation of developmental process GO:0051093 247 0.014
response to axon injury GO:0048678 1 0.014
organelle assembly GO:0070925 176 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
positive regulation of organelle organization GO:0010638 195 0.014
vesicle mediated transport GO:0016192 371 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
atp metabolic process GO:0046034 176 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
single organism membrane organization GO:0044802 268 0.013
regulation of cell migration GO:0030334 289 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
metencephalon development GO:0022037 2 0.013
stem cell division GO:0017145 2 0.013
actin filament based movement GO:0030048 17 0.013
motor neuron axon guidance GO:0008045 2 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
positive regulation of immune system process GO:0002684 283 0.013
regulation of feeding behavior GO:0060259 3 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
cell part morphogenesis GO:0032990 137 0.013
limbic system development GO:0021761 3 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
positive regulation of cell proliferation GO:0008284 301 0.013
rna processing GO:0006396 255 0.013
cell activation GO:0001775 213 0.013
multi organism cellular process GO:0044764 156 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
actin cytoskeleton organization GO:0030036 207 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
dna repair GO:0006281 198 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
positive regulation of kinase activity GO:0033674 204 0.012
lipid biosynthetic process GO:0008610 177 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
inner ear morphogenesis GO:0042472 4 0.012
cellular homeostasis GO:0019725 196 0.012
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
nitrogen compound transport GO:0071705 191 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
negative regulation of organelle organization GO:0010639 126 0.012
associative learning GO:0008306 1 0.012
metal ion homeostasis GO:0055065 169 0.012
detection of stimulus GO:0051606 85 0.012
compound eye development GO:0048749 1 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
regulation of growth GO:0040008 165 0.012
visual behavior GO:0007632 2 0.012
endosomal transport GO:0016197 129 0.012
visual learning GO:0008542 1 0.012
interspecies interaction between organisms GO:0044419 156 0.012
regulation of meiosis GO:0040020 3 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
lipid transport GO:0006869 90 0.012
cell division GO:0051301 168 0.012
cellular lipid metabolic process GO:0044255 303 0.012
response to fungus GO:0009620 4 0.012
regulation of immune response GO:0050776 201 0.012
nerve development GO:0021675 4 0.012
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.012
cgmp catabolic process GO:0046069 3 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
meiosis i GO:0007127 4 0.012
cell projection morphogenesis GO:0048858 129 0.012
sulfur compound metabolic process GO:0006790 101 0.012
cell morphogenesis involved in differentiation GO:0000904 144 0.012
regulation of cell growth GO:0001558 135 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
positive regulation of axon extension GO:0045773 4 0.012
cation homeostasis GO:0055080 189 0.012
Human
regulation of axon guidance GO:1902667 3 0.012
neurotransmitter secretion GO:0007269 4 0.012
regulation of gtpase activity GO:0043087 180 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
tissue regeneration GO:0042246 3 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
cell cycle phase transition GO:0044770 173 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
regulation of cell motility GO:2000145 299 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
negative regulation of transferase activity GO:0051348 124 0.011
neuron projection regeneration GO:0031102 1 0.011
protein oligomerization GO:0051259 173 0.011
divalent inorganic cation transport GO:0072511 158 0.011
calcium ion transport GO:0006816 147 0.011
nuclear transport GO:0051169 179 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
cation transport GO:0006812 331 0.011
Human
protein modification by small protein removal GO:0070646 92 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
tripartite regional subdivision GO:0007351 2 0.011
peptidyl lysine modification GO:0018205 144 0.011
protein homooligomerization GO:0051260 100 0.011
regulation of locomotion GO:0040012 329 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
regulation of intracellular transport GO:0032386 195 0.011
response to radiation GO:0009314 151 0.011
protein localization to membrane GO:0072657 160 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
neurogenesis GO:0022008 169 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
salivary gland morphogenesis GO:0007435 4 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
melanin metabolic process GO:0006582 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
response to organic cyclic compound GO:0014070 204 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
myoblast fusion GO:0007520 1 0.011
thymus development GO:0048538 3 0.011
divalent metal ion transport GO:0070838 152 0.011
t cell differentiation in thymus GO:0033077 4 0.011
actin mediated cell contraction GO:0070252 12 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
regulation of protein maturation GO:1903317 150 0.011
long term memory GO:0007616 2 0.011
mrna metabolic process GO:0016071 175 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
embryonic forelimb morphogenesis GO:0035115 4 0.011
generation of neurons GO:0048699 152 0.011
ion homeostasis GO:0050801 230 0.010
Human
organelle fission GO:0048285 149 0.010
lung alveolus development GO:0048286 4 0.010
establishment of protein localization to membrane GO:0090150 121 0.010
positive regulation of transferase activity GO:0051347 227 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
leukocyte activation GO:0045321 164 0.010
ribonucleoside monophosphate catabolic process GO:0009158 158 0.010
protein autophosphorylation GO:0046777 123 0.010
positive regulation of cell cycle GO:0045787 140 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
positive regulation of cellular component movement GO:0051272 181 0.010
cerebellum development GO:0021549 2 0.010
regulation of endopeptidase activity GO:0052548 170 0.010
regulation of protein processing GO:0070613 150 0.010
myosin filament assembly GO:0031034 2 0.010
nucleocytoplasmic transport GO:0006913 176 0.010
neuron projection development GO:0031175 106 0.010
mitotic nuclear division GO:0007067 119 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
response to bacterium GO:0009617 144 0.010
epidermis morphogenesis GO:0048730 3 0.010
intracellular receptor signaling pathway GO:0030522 104 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
regulation of protein transport GO:0051223 213 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
response to activity GO:0014823 0 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
negative regulation of protein processing GO:0010955 142 0.010
myosin filament organization GO:0031033 2 0.010
regulation of protein complex assembly GO:0043254 147 0.010
calcium ion homeostasis GO:0055074 122 0.010
blood vessel development GO:0001568 172 0.010
viral life cycle GO:0019058 132 0.010
positive regulation of synaptic transmission GO:0050806 4 0.010
wnt signaling pathway GO:0016055 156 0.010
circulatory system development GO:0072359 262 0.010

SLC4A5 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.053
Human
nervous system disease DOID:863 431 0.053
Human
disease of metabolism DOID:0014667 295 0.034
eye and adnexa disease DOID:1492 150 0.030
Human
eye disease DOID:5614 149 0.030
Human
musculoskeletal system disease DOID:17 223 0.027
inherited metabolic disorder DOID:655 242 0.022
immune system disease DOID:2914 155 0.022
Human
retinal disease DOID:5679 118 0.022
central nervous system disease DOID:331 186 0.020
retinal degeneration DOID:8466 89 0.019
disease of cellular proliferation DOID:14566 174 0.019
cancer DOID:162 167 0.018
organ system cancer DOID:0050686 164 0.018
neurodegenerative disease DOID:1289 102 0.016
cardiovascular system disease DOID:1287 106 0.015
connective tissue disease DOID:65 109 0.015
hematopoietic system disease DOID:74 100 0.014
Human
disease of mental health DOID:150 70 0.013
bone disease DOID:0080001 88 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012