|
|
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:2001189 |
1 |
1.000
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
1 |
1.000
|
|
|
|
negative regulation of interleukin 12 secretion
|
GO:2001183 |
1 |
1.000
|
|
|
|
type i interferon secretion
|
GO:0072641 |
1 |
1.000
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
3 |
1.000
|
|
|
|
regulation of gamma delta t cell activation involved in immune response
|
GO:2001191 |
1 |
1.000
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
2 |
0.999
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
4 |
0.999
|
|
|
|
negative regulation of interferon gamma biosynthetic process
|
GO:0045077 |
1 |
0.999
|
|
|
|
negative regulation of interleukin 10 production
|
GO:0032693 |
7 |
0.999
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
4 |
0.999
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.998
|
|
|
|
regulation of interferon beta secretion
|
GO:0035547 |
1 |
0.998
|
|
|
|
negative regulation of transforming growth factor beta secretion
|
GO:2001202 |
1 |
0.998
|
|
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
3 |
0.998
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
1 |
0.996
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
1 |
0.995
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
4 |
0.995
|
|
|
|
negative regulation of dendritic cell differentiation
|
GO:2001199 |
2 |
0.995
|
|
|
|
interferon beta secretion
|
GO:0035546 |
1 |
0.994
|
|
|
|
regulation of osteoclast development
|
GO:2001204 |
1 |
0.988
|
|
|
|
serotonin transport
|
GO:0006837 |
3 |
0.986
|
|
|
|
negative regulation of dendritic cell apoptotic process
|
GO:2000669 |
3 |
0.985
|
|
|
|
regulation of transforming growth factor beta secretion
|
GO:2001201 |
1 |
0.983
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
3 |
0.975
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
4 |
0.973
|
|
|
|
positive regulation of gamma delta t cell activation involved in immune response
|
GO:2001193 |
1 |
0.972
|
|
|
|
osteoclast development
|
GO:0036035 |
2 |
0.964
|
|
|
|
interferon gamma biosynthetic process
|
GO:0042095 |
8 |
0.963
|
|
|
|
t cell proliferation involved in immune response
|
GO:0002309 |
1 |
0.962
|
|
|
|
gamma delta t cell activation involved in immune response
|
GO:0002290 |
1 |
0.940
|
|
|
|
positive regulation of cytolysis
|
GO:0045919 |
3 |
0.938
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
8 |
0.937
|
|
|
|
negative regulation of interferon beta secretion
|
GO:0035548 |
1 |
0.934
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
3 |
0.916
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.916
|
|
|
|
serotonin secretion
|
GO:0001820 |
1 |
0.915
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
1 |
0.914
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.901
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.900
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
4 |
0.898
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
16 |
0.895
|
|
|
|
negative regulation of osteoclast development
|
GO:2001205 |
1 |
0.895
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
1 |
0.894
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
19 |
0.894
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.886
|
Mouse |
|
|
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:2001188 |
2 |
0.846
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
8 |
0.843
|
|
|
|
regulation of interferon gamma biosynthetic process
|
GO:0045072 |
8 |
0.838
|
|
|
|
regulation of t cell tolerance induction
|
GO:0002664 |
4 |
0.831
|
|
|
|
negative regulation of cytokine production involved in immune response
|
GO:0002719 |
13 |
0.828
|
|
|
|
transforming growth factor beta secretion
|
GO:0038044 |
1 |
0.819
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.806
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.791
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.775
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.772
|
Mouse |
|
|
negative regulation of calcium ion transport
|
GO:0051926 |
19 |
0.755
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.753
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.750
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.744
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.743
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.743
|
|
|
|
t cell tolerance induction
|
GO:0002517 |
4 |
0.730
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.705
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
1 |
0.701
|
|
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
1 |
0.696
|
|
|
|
regulation of dendritic cell differentiation
|
GO:2001198 |
3 |
0.693
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.680
|
|
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
5 |
0.650
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.649
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.647
|
|
|
|
regulation of cytokine secretion involved in immune response
|
GO:0002739 |
7 |
0.645
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.643
|
|
|
|
interferon gamma secretion
|
GO:0072643 |
6 |
0.632
|
|
|
|
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:0002291 |
4 |
0.626
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.622
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.612
|
Mouse |
|
|
negative regulation of type i interferon production
|
GO:0032480 |
5 |
0.609
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.586
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.581
|
|
|
|
negative regulation of production of molecular mediator of immune response
|
GO:0002701 |
13 |
0.577
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.572
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.564
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
13 |
0.551
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
13 |
0.551
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
23 |
0.546
|
|
|
|
cytolysis
|
GO:0019835 |
8 |
0.542
|
|
|
|
monoamine transport
|
GO:0015844 |
10 |
0.538
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.538
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
8 |
0.522
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.521
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
27 |
0.511
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.511
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.504
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
2 |
0.502
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
12 |
0.500
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.497
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
16 |
0.493
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
20 |
0.487
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.479
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.479
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.465
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.461
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.454
|
|
|
|
myeloid cell development
|
GO:0061515 |
5 |
0.452
|
|
|
|
negative regulation of antigen processing and presentation
|
GO:0002578 |
5 |
0.451
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.450
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
9 |
0.444
|
|
|
|
negative regulation of natural killer cell mediated cytotoxicity
|
GO:0045953 |
5 |
0.433
|
|
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.423
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
13 |
0.419
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.418
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.415
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
33 |
0.408
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.407
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.402
|
|
|
|
phagocytosis recognition
|
GO:0006910 |
3 |
0.399
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.393
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.392
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.383
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.376
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.373
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.371
|
Mouse |
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.367
|
Mouse |
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.365
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.365
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.361
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.358
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.354
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.349
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.347
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.342
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.341
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.339
|
Mouse |
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
11 |
0.335
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
14 |
0.329
|
|
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
7 |
0.326
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.319
|
Mouse |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.317
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
5 |
0.312
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.311
|
|
|
|
cell killing
|
GO:0001906 |
34 |
0.301
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.295
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.294
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.280
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
15 |
0.280
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.279
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.279
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.276
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.274
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.272
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.272
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.270
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.269
|
|
|
|
regulation of interleukin 12 secretion
|
GO:2001182 |
1 |
0.265
|
|
|
|
detection of muramyl dipeptide
|
GO:0032498 |
1 |
0.263
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.257
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.252
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.251
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.250
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.250
|
|
|
|
negative regulation of mononuclear cell proliferation
|
GO:0032945 |
15 |
0.240
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.240
|
|
|
|
regulation of tolerance induction
|
GO:0002643 |
4 |
0.238
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
23 |
0.234
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
20 |
0.228
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.228
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.228
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.224
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.223
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.223
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.222
|
|
|
|
regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002923 |
3 |
0.220
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.216
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.214
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.214
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.214
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.214
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.213
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.210
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.207
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.206
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
16 |
0.206
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.205
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.205
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.205
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.202
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
6 |
0.202
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.202
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.194
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.189
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.187
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.187
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.185
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.184
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.183
|
|
|
|
negative regulation of cytokine secretion
|
GO:0050710 |
20 |
0.179
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.178
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
16 |
0.178
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.175
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.171
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.170
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.165
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.165
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.161
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
25 |
0.161
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
20 |
0.161
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.156
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.153
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.153
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.152
|
Mouse |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.150
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.150
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.148
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.148
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.148
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.146
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.145
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.144
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.143
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.142
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.142
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.141
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.139
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.138
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.138
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.134
|
|
|
|
negative regulation of b cell mediated immunity
|
GO:0002713 |
3 |
0.133
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.131
|
|
|
|
platelet formation
|
GO:0030220 |
4 |
0.131
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.130
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.126
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.124
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.123
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.122
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.122
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.121
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.120
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
8 |
0.118
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.118
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.117
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
9 |
0.116
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.115
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.115
|
|
|
|
negative regulation of osteoclast differentiation
|
GO:0045671 |
8 |
0.114
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.113
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.113
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.112
|
|
|
|
negative regulation of cytokine secretion involved in immune response
|
GO:0002740 |
5 |
0.111
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.107
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.107
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.106
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
11 |
0.104
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.103
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
8 |
0.102
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.099
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.096
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.095
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
9 |
0.094
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.090
|
|
|
|
nk t cell activation
|
GO:0051132 |
4 |
0.087
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.086
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.086
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
22 |
0.084
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.084
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.083
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.082
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
24 |
0.082
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.082
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.082
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.082
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.081
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.080
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.079
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.079
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.079
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.078
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.078
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.077
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.077
|
|
|
|
negative regulation of leukocyte mediated cytotoxicity
|
GO:0001911 |
5 |
0.077
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.076
|
|
|
|
regulation of cell killing
|
GO:0031341 |
22 |
0.075
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.075
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.071
|
|
|
|
negative regulation of cell killing
|
GO:0031342 |
5 |
0.071
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.068
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.068
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.068
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.067
|
|
|
|
tolerance induction
|
GO:0002507 |
6 |
0.066
|
|
|
|
interleukin 12 production
|
GO:0032615 |
15 |
0.065
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.064
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.064
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.063
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.063
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.062
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.062
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.062
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.062
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
15 |
0.062
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.061
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.061
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.060
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.060
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.060
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.058
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.056
|
|
|
|
regulatory t cell differentiation
|
GO:0045066 |
5 |
0.056
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.056
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.054
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.054
|
|
|
|
negative regulation of activation of jak2 kinase activity
|
GO:1902569 |
1 |
0.054
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.053
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.053
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.051
|
Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.051
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.050
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.050
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.050
|
Mouse |
|
|
interleukin 10 production
|
GO:0032613 |
17 |
0.050
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.050
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.050
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.050
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.049
|
|
|
|
negative regulation of cd8 positive alpha beta t cell activation
|
GO:2001186 |
1 |
0.049
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.048
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.047
|
|
|
|
negative regulation of nk t cell activation
|
GO:0051134 |
1 |
0.047
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.046
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.046
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
18 |
0.046
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.045
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.045
|
|
|
|
positive regulation of tolerance induction
|
GO:0002645 |
2 |
0.045
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.045
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.045
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
18 |
0.044
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.044
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.043
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.043
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.043
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.043
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.043
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.043
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.043
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
1 |
0.042
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.041
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.041
|
|
|
|
detection of peptidoglycan
|
GO:0032499 |
1 |
0.041
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.041
|
Mouse |
|
|
positive regulation of t helper cell differentiation
|
GO:0045624 |
2 |
0.040
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.040
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.040
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.040
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.039
|
|
|
|
hepoxilin metabolic process
|
GO:0051121 |
1 |
0.039
|
|
|
|
immune response in mucosal associated lymphoid tissue
|
GO:0002386 |
1 |
0.039
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.039
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.038
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
19 |
0.038
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.038
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.038
|
Mouse |
|
|
head development
|
GO:0060322 |
108 |
0.038
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.038
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.036
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.036
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.036
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.035
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.035
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.035
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.035
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.035
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.035
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.035
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.034
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.034
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.034
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.034
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.034
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.034
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.034
|
|
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.034
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.033
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.033
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.033
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.033
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.033
|
|
|
|
positive regulation of glucose import in response to insulin stimulus
|
GO:2001275 |
3 |
0.032
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.032
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.032
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.031
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.030
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.030
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.030
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.030
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.029
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.029
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.029
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.028
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.028
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.028
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.027
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.027
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.027
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.027
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.027
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.027
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.027
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.027
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.027
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.027
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.027
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.026
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.026
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.026
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.026
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.026
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.026
|
|
|
|
positive regulation of cell adhesion mediated by integrin
|
GO:0033630 |
9 |
0.026
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.026
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.026
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
42 |
0.026
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.026
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.026
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.025
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.025
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.025
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.025
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.025
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.025
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.025
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.025
|
|
|
|
negative regulation of phagocytosis engulfment
|
GO:0060101 |
1 |
0.025
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.025
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.025
|
|
|
|
negative regulation of immunoglobulin mediated immune response
|
GO:0002890 |
3 |
0.025
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.024
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.024
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.024
|
|
|
|
regulation of cytolysis
|
GO:0042268 |
6 |
0.024
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.024
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.024
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.024
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.024
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.024
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.024
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.024
|
|
|
|
lipoxygenase pathway
|
GO:0019372 |
4 |
0.024
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.024
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.023
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.023
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.023
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.023
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.023
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.023
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.023
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.023
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.022
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
19 |
0.022
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.022
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.022
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.022
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.022
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.022
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.022
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.022
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.022
|
|
|
|
positive regulation of mhc class i biosynthetic process
|
GO:0045345 |
4 |
0.022
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.022
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.022
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.021
|
|
|
|
polyol metabolic process
|
GO:0019751 |
32 |
0.021
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.021
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.021
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.021
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.021
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.021
|
|
|
|
response to diacyl bacterial lipopeptide
|
GO:0071724 |
2 |
0.021
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.021
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
1 |
0.021
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.021
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.020
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.020
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.020
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
