Homo sapiens

22 known processes

INTS1

integrator complex subunit 1

(Aliases: FLJ46624,DKFZp586J0619,INT1,KIAA1440,NET28)

INTS1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.258
morphogenesis of embryonic epithelium GO:0016331 4 0.142
nucleoside catabolic process GO:0009164 408 0.121
purine nucleoside triphosphate catabolic process GO:0009146 392 0.098
rna processing GO:0006396 255 0.096
snrna metabolic process GO:0016073 15 0.085
ribonucleoside catabolic process GO:0042454 406 0.084
membrane organization GO:0061024 292 0.082
neural tube formation GO:0001841 3 0.080
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.079
small gtpase mediated signal transduction GO:0007264 78 0.068
nucleoside phosphate catabolic process GO:1901292 412 0.068
glycosyl compound catabolic process GO:1901658 413 0.068
nervous system development GO:0007399 293 0.067
organophosphate catabolic process GO:0046434 430 0.066
ribonucleoside triphosphate metabolic process GO:0009199 412 0.065
ribonucleoside triphosphate catabolic process GO:0009203 391 0.064
nucleotide catabolic process GO:0009166 408 0.063
gtp metabolic process GO:0046039 239 0.063
regulation of purine nucleotide catabolic process GO:0033121 205 0.060
purine containing compound catabolic process GO:0072523 411 0.060
positive regulation of cellular catabolic process GO:0031331 284 0.060
oogenesis GO:0048477 2 0.059
nucleoside triphosphate catabolic process GO:0009143 394 0.058
purine ribonucleotide catabolic process GO:0009154 404 0.057
gtp catabolic process GO:0006184 237 0.057
epithelium development GO:0060429 227 0.056
visual behavior GO:0007632 2 0.056
primary neural tube formation GO:0014020 3 0.055
purine ribonucleoside metabolic process GO:0046128 437 0.054
vesicle mediated transport GO:0016192 371 0.053
purine nucleoside catabolic process GO:0006152 398 0.052
regulation of nucleotide catabolic process GO:0030811 205 0.052
signal transduction by phosphorylation GO:0023014 297 0.051
purine nucleotide catabolic process GO:0006195 405 0.051
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.051
positive regulation of nucleoside metabolic process GO:0045979 186 0.049
ribonucleotide catabolic process GO:0009261 405 0.049
multicellular organismal aging GO:0010259 3 0.045
positive regulation of catabolic process GO:0009896 310 0.045
response to abiotic stimulus GO:0009628 336 0.044
microtubule based process GO:0007017 210 0.044
single organism membrane organization GO:0044802 268 0.043
regulation of mapk cascade GO:0043408 262 0.043
single organism cellular localization GO:1902580 332 0.043
visual learning GO:0008542 1 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.040
rho protein signal transduction GO:0007266 26 0.039
purine ribonucleoside catabolic process GO:0046130 398 0.039
ras protein signal transduction GO:0007265 73 0.039
mitotic cell cycle GO:0000278 326 0.038
female gamete generation GO:0007292 2 0.038
determination of adult lifespan GO:0008340 2 0.037
ncrna metabolic process GO:0034660 108 0.037
response to radiation GO:0009314 151 0.037
cellular response to dna damage stimulus GO:0006974 379 0.035
positive regulation of nucleotide metabolic process GO:0045981 230 0.034
neural tube closure GO:0001843 3 0.034
apoptotic signaling pathway GO:0097190 268 0.034
associative learning GO:0008306 1 0.034
cellular ketone metabolic process GO:0042180 80 0.033
dna repair GO:0006281 198 0.033
regulation of cell migration GO:0030334 289 0.033
regulation of gtp catabolic process GO:0033124 180 0.033
mrna processing GO:0006397 133 0.032
cytoplasmic transport GO:0016482 379 0.031
regulation of cell motility GO:2000145 299 0.031
regulation of gtpase activity GO:0043087 180 0.031
immune response GO:0006955 307 0.030
defense response GO:0006952 315 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.029
protein localization to membrane GO:0072657 160 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
rna 3 end processing GO:0031123 35 0.029
response to light stimulus GO:0009416 87 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
endosomal transport GO:0016197 129 0.029
regulation of cell cycle phase transition GO:1901987 126 0.029
amine metabolic process GO:0009308 44 0.028
ncrna processing GO:0034470 83 0.028
mitotic cell cycle process GO:1903047 286 0.028
dephosphorylation GO:0016311 209 0.028
intracellular protein transport GO:0006886 270 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of cellular component movement GO:0051270 334 0.027
tube development GO:0035295 125 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.027
positive regulation of gtp catabolic process GO:0033126 166 0.027
mrna metabolic process GO:0016071 175 0.027
multicellular organismal response to stress GO:0033555 1 0.026
oocyte differentiation GO:0009994 2 0.026
cellular macromolecule catabolic process GO:0044265 380 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
positive regulation of developmental process GO:0051094 314 0.025
regulation of locomotion GO:0040012 329 0.025
regeneration GO:0031099 4 0.025
positive regulation of gtpase activity GO:0043547 166 0.025
guanosine containing compound metabolic process GO:1901068 244 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
locomotory behavior GO:0007626 1 0.023
cell cycle phase transition GO:0044770 173 0.023
regulation of cell cycle GO:0051726 393 0.023
negative regulation of catalytic activity GO:0043086 335 0.022
oocyte development GO:0048599 1 0.022
regulation of epithelial cell proliferation GO:0050678 113 0.022
microtubule cytoskeleton organization GO:0000226 176 0.022
cellular amine metabolic process GO:0044106 41 0.022
positive regulation of cell migration GO:0030335 172 0.022
system process GO:0003008 349 0.022
organelle fission GO:0048285 149 0.022
regulation of cellular component biogenesis GO:0044087 281 0.021
protein localization to organelle GO:0033365 280 0.021
snrna processing GO:0016180 14 0.021
mapk cascade GO:0000165 288 0.021
hematopoietic or lymphoid organ development GO:0048534 186 0.021
negative regulation of cell death GO:0060548 345 0.021
regulation of immune response GO:0050776 201 0.021
fear response GO:0042596 0 0.021
cardiovascular system development GO:0072358 262 0.020
regulation of nucleotide metabolic process GO:0006140 269 0.020
regulation of ras protein signal transduction GO:0046578 155 0.020
regulation of protein serine threonine kinase activity GO:0071900 179 0.020
cellular homeostasis GO:0019725 196 0.020
endomembrane system organization GO:0010256 196 0.020
regulation of cellular response to stress GO:0080135 244 0.020
regulation of protein kinase activity GO:0045859 289 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
positive regulation of cell motility GO:2000147 177 0.019
cell morphogenesis GO:0000902 296 0.019
protein catabolic process GO:0030163 325 0.019
response to oxygen containing compound GO:1901700 369 0.019
cell projection organization GO:0030030 252 0.019
segmentation GO:0035282 4 0.019
spermatid development GO:0007286 4 0.019
cell adhesion GO:0007155 325 0.019
regulation of kinase activity GO:0043549 314 0.019
protein modification by small protein conjugation GO:0032446 342 0.018
histone modification GO:0016570 251 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
regulation of growth GO:0040008 165 0.018
regulation of cell differentiation GO:0045595 393 0.018
tube morphogenesis GO:0035239 95 0.018
regulation of response to external stimulus GO:0032101 222 0.018
spermatid differentiation GO:0048515 4 0.018
biological adhesion GO:0022610 331 0.018
neuromuscular junction development GO:0007528 3 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
carbohydrate metabolic process GO:0005975 207 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
organelle localization GO:0051640 84 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
immune system development GO:0002520 195 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
cell cycle checkpoint GO:0000075 117 0.017
positive regulation of transferase activity GO:0051347 227 0.017
mitochondrial membrane organization GO:0007006 40 0.017
neurogenesis GO:0022008 169 0.016
cellular protein catabolic process GO:0044257 261 0.016
positive regulation of nucleotide catabolic process GO:0030813 185 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
posttranscriptional regulation of gene expression GO:0010608 213 0.016
cellular amino acid metabolic process GO:0006520 116 0.016
behavioral defense response GO:0002209 0 0.016
response to fungus GO:0009620 4 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
regulation of transferase activity GO:0051338 355 0.016
blastoderm segmentation GO:0007350 2 0.016
circulatory system development GO:0072359 262 0.016
generation of neurons GO:0048699 152 0.015
negative regulation of cellular protein metabolic process GO:0032269 353 0.015
chromatin organization GO:0006325 351 0.015
autophagy GO:0006914 88 0.015
positive regulation of locomotion GO:0040017 186 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
cell development GO:0048468 328 0.015
epithelial cell proliferation GO:0050673 128 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
protein autophosphorylation GO:0046777 123 0.015
cell fate determination GO:0001709 3 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
cell growth GO:0016049 160 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
neurotransmitter secretion GO:0007269 4 0.015
protein targeting GO:0006605 187 0.015
negative regulation of transport GO:0051051 176 0.015
actin filament based process GO:0030029 224 0.015
protein ubiquitination GO:0016567 314 0.015
cell projection morphogenesis GO:0048858 129 0.015
cellular response to extracellular stimulus GO:0031668 72 0.015
maintenance of location GO:0051235 112 0.014
response to nutrient levels GO:0031667 81 0.014
response to extracellular stimulus GO:0009991 85 0.014
regulation of cell development GO:0060284 161 0.014
regulation of dephosphorylation GO:0035303 96 0.014
regulation of protein catabolic process GO:0042176 155 0.014
rna interference GO:0016246 4 0.014
anterior posterior axis specification GO:0009948 2 0.014
positive regulation of hydrolase activity GO:0051345 331 0.014
regulation of proteolysis GO:0030162 293 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
regulation of cellular amine metabolic process GO:0033238 11 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
negative regulation of locomotion GO:0040013 118 0.014
positive regulation of transport GO:0051050 336 0.014
positive regulation of kinase activity GO:0033674 204 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
actin cytoskeleton organization GO:0030036 207 0.014
rna splicing GO:0008380 131 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
protein methylation GO:0006479 74 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
compound eye development GO:0048749 1 0.013
response to starvation GO:0042594 59 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
embryonic morphogenesis GO:0048598 85 0.013
ion homeostasis GO:0050801 230 0.013
plasma membrane organization GO:0007009 115 0.013
wnt signaling pathway GO:0016055 156 0.013
secretion by cell GO:0032940 226 0.013
protein maturation GO:0051604 233 0.013
alcohol metabolic process GO:0006066 114 0.013
embryo development GO:0009790 123 0.012
regulation of cellular amino acid metabolic process GO:0006521 6 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
macromolecule methylation GO:0043414 97 0.012
regulation of protein localization GO:0032880 296 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
tissue morphogenesis GO:0048729 96 0.012
cell part morphogenesis GO:0032990 137 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
regulation of dna metabolic process GO:0051052 153 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
regulation of cell adhesion GO:0030155 166 0.012
head development GO:0060322 108 0.012
regulation of response to wounding GO:1903034 101 0.012
rab protein signal transduction GO:0032482 4 0.012
neuroblast proliferation GO:0007405 4 0.012
cellular response to nutrient levels GO:0031669 69 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
negative regulation of cell cycle GO:0045786 193 0.012
cellular component morphogenesis GO:0032989 314 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of protein transport GO:0051223 213 0.012
protein localization to plasma membrane GO:0072659 93 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
blood vessel development GO:0001568 172 0.011
regulation of neuron migration GO:2001222 3 0.011
regulation of autophagy GO:0010506 52 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
chemical homeostasis GO:0048878 306 0.011
memory GO:0007613 3 0.011
regulation of cell growth GO:0001558 135 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
behavioral fear response GO:0001662 0 0.011
innate immune response GO:0045087 178 0.011
peptidyl lysine modification GO:0018205 144 0.011
growth GO:0040007 202 0.011
mitochondrial transport GO:0006839 60 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
endocytosis GO:0006897 159 0.011
tripartite regional subdivision GO:0007351 2 0.011
protein dephosphorylation GO:0006470 81 0.011
nuclear division GO:0000280 128 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
behavior GO:0007610 112 0.011
regulation of phosphatase activity GO:0010921 81 0.011
positive regulation of neurogenesis GO:0050769 49 0.011
vesicle organization GO:0016050 62 0.011
embryonic placenta development GO:0001892 1 0.011
secretion GO:0046903 254 0.011
positive regulation of cell development GO:0010720 92 0.011
cellular response to external stimulus GO:0071496 111 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
dna recombination GO:0006310 77 0.011
rhythmic behavior GO:0007622 2 0.011
regulation of intracellular transport GO:0032386 195 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
neurological system process GO:0050877 163 0.011
intracellular mrna localization GO:0008298 1 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
camp metabolic process GO:0046058 61 0.010
organonitrogen compound biosynthetic process GO:1901566 200 0.010
chromosome segregation GO:0007059 114 0.010
cell morphogenesis involved in differentiation GO:0000904 144 0.010
response to other organism GO:0051707 261 0.010
epithelial cell differentiation GO:0030855 141 0.010
mitochondrion organization GO:0007005 156 0.010
anterior posterior axis specification embryo GO:0008595 2 0.010
cell substrate adhesion GO:0031589 132 0.010
cellular response to hormone stimulus GO:0032870 125 0.010
regulation of ras gtpase activity GO:0032318 128 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
response to biotic stimulus GO:0009607 276 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
transmembrane transport GO:0055085 399 0.010
gland development GO:0048732 48 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
tissue migration GO:0090130 119 0.010

INTS1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.043
nervous system disease DOID:863 431 0.043
musculoskeletal system disease DOID:17 223 0.028
cancer DOID:162 167 0.022
disease of cellular proliferation DOID:14566 174 0.022
organ system cancer DOID:0050686 164 0.018
muscular disease DOID:0080000 114 0.012
sensory system disease DOID:0050155 203 0.011
connective tissue disease DOID:65 109 0.011
myopathy DOID:423 104 0.010
muscle tissue disease DOID:66 113 0.010
eye and adnexa disease DOID:1492 150 0.010