Homo sapiens

0 known processes

G3BP1

GTPase activating protein (SH3 domain) binding protein 1

(Aliases: HDH-VIII,MGC111040,G3BP)

G3BP1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of translation GO:0006417 89 0.993
posttranscriptional regulation of gene expression GO:0010608 213 0.792
mitotic cell cycle process GO:1903047 286 0.711
translation GO:0006412 132 0.658
determination of adult lifespan GO:0008340 2 0.611
regulation of mitotic cell cycle GO:0007346 189 0.417
rna processing GO:0006396 255 0.391
negative regulation of cellular protein metabolic process GO:0032269 353 0.347
mitotic cell cycle GO:0000278 326 0.338
positive regulation of developmental process GO:0051094 314 0.328
ribosomal small subunit biogenesis GO:0042274 13 0.322
mitotic nuclear division GO:0007067 119 0.319
post embryonic development GO:0009791 2 0.311
Worm
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.297
negative regulation of protein metabolic process GO:0051248 391 0.251
regulation of cell cycle GO:0051726 393 0.212
protein modification by small protein removal GO:0070646 92 0.203
multicellular organismal aging GO:0010259 3 0.199
translational initiation GO:0006413 48 0.197
regeneration GO:0031099 4 0.193
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.188
ribonucleoprotein complex biogenesis GO:0022613 116 0.187
posttranscriptional gene silencing by rna GO:0035194 25 0.175
response to abiotic stimulus GO:0009628 336 0.175
sister chromatid segregation GO:0000819 54 0.172
cell growth GO:0016049 160 0.167
positive regulation of dendritic spine development GO:0060999 2 0.159
stem cell development GO:0048864 69 0.150
negative regulation of catalytic activity GO:0043086 335 0.144
cellular response to dna damage stimulus GO:0006974 379 0.140
gene silencing GO:0016458 49 0.137
chromatin organization GO:0006325 351 0.134
regulation of neuron differentiation GO:0045664 70 0.128
maintenance of location GO:0051235 112 0.119
spermatid development GO:0007286 4 0.115
multicellular organismal homeostasis GO:0048871 67 0.110
oogenesis GO:0048477 2 0.107
Fly
regulation of gene expression epigenetic GO:0040029 73 0.099
ncrna metabolic process GO:0034660 108 0.097
positive regulation of growth GO:0045927 58 0.096
regulation of cell division GO:0051302 116 0.095
cell development GO:0048468 328 0.094
Fly
regulation of mitosis GO:0007088 63 0.092
cellular component morphogenesis GO:0032989 314 0.089
regulation of nuclear division GO:0051783 65 0.088
gene silencing by rna GO:0031047 26 0.087
modification dependent protein catabolic process GO:0019941 209 0.084
locomotory behavior GO:0007626 1 0.083
rrna metabolic process GO:0016072 40 0.082
retina homeostasis GO:0001895 42 0.080
response to nitrogen compound GO:1901698 184 0.079
cytoplasmic transport GO:0016482 379 0.079
gene silencing by mirna GO:0035195 23 0.077
rna interference GO:0016246 4 0.075
regulation of cell differentiation GO:0045595 393 0.075
embryo development GO:0009790 123 0.075
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.074
cell morphogenesis involved in differentiation GO:0000904 144 0.070
maturation of ssu rrna GO:0030490 3 0.069
regulation of growth GO:0040008 165 0.068
Fly
adult locomotory behavior GO:0008344 1 0.067
cell cycle phase transition GO:0044770 173 0.067
regulation of anatomical structure morphogenesis GO:0022603 286 0.066
regulation of translational initiation GO:0006446 24 0.066
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.065
dendritic spine morphogenesis GO:0060997 3 0.063
female gamete generation GO:0007292 2 0.062
Fly
response to peptide GO:1901652 65 0.062
amine metabolic process GO:0009308 44 0.061
small gtpase mediated signal transduction GO:0007264 78 0.061
Fly
organelle fission GO:0048285 149 0.061
spermatid differentiation GO:0048515 4 0.060
cell junction organization GO:0034330 79 0.059
osteoblast differentiation GO:0001649 92 0.059
intracellular protein transport GO:0006886 270 0.059
regulation of meiosis GO:0040020 3 0.059
regulation of sister chromatid segregation GO:0033045 27 0.058
neurogenesis GO:0022008 169 0.057
Fly
tissue homeostasis GO:0001894 63 0.057
modification dependent macromolecule catabolic process GO:0043632 212 0.057
protein deubiquitination GO:0016579 79 0.055
negative regulation of multi organism process GO:0043901 92 0.053
cellular response to hormone stimulus GO:0032870 125 0.051
developmental growth GO:0048589 48 0.050
Fly
mrna metabolic process GO:0016071 175 0.050
negative regulation of proteolysis GO:0045861 132 0.050
regulation of homeostatic process GO:0032844 121 0.049
establishment of nucleus localization GO:0040023 1 0.049
7 methylguanosine mrna capping GO:0006370 7 0.049
regulation of cytokine production GO:0001817 232 0.049
ribosome biogenesis GO:0042254 48 0.048
cellular response to peptide hormone stimulus GO:0071375 56 0.047
regulation of cell growth GO:0001558 135 0.047
regulation of protein localization GO:0032880 296 0.046
immune response regulating signaling pathway GO:0002764 97 0.046
activation of immune response GO:0002253 114 0.045
chromatin modification GO:0016568 298 0.045
response to organonitrogen compound GO:0010243 156 0.045
ncrna processing GO:0034470 83 0.044
cellular macromolecule catabolic process GO:0044265 380 0.044
reproduction GO:0000003 63 0.044
Fly
nervous system development GO:0007399 293 0.043
Fly
regulation of proteasomal protein catabolic process GO:0061136 87 0.042
anatomical structure homeostasis GO:0060249 100 0.042
regulation of establishment of protein localization GO:0070201 242 0.041
lipid biosynthetic process GO:0008610 177 0.041
regulation of proteolysis GO:0030162 293 0.041
response to virus GO:0009615 126 0.040
negative regulation of translation GO:0017148 37 0.038
regulation of protein processing GO:0070613 150 0.038
axon extension GO:0048675 13 0.038
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.038
aging GO:0007568 66 0.037
immune response activating signal transduction GO:0002757 90 0.037
cellular response to nitrogen compound GO:1901699 144 0.037
regulation of cell cycle process GO:0010564 266 0.037
regulation of cellular component biogenesis GO:0044087 281 0.037
cytokine production GO:0001816 247 0.037
protein maturation GO:0051604 233 0.036
cellular protein catabolic process GO:0044257 261 0.036
peptidyl tyrosine modification GO:0018212 170 0.035
positive regulation of mrna metabolic process GO:1903313 19 0.035
neuromuscular junction development GO:0007528 3 0.034
positive regulation of cell proliferation GO:0008284 301 0.034
regulation of mrna metabolic process GO:1903311 53 0.034
regulation of apoptotic signaling pathway GO:2001233 175 0.033
cellular amino acid metabolic process GO:0006520 116 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.033
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.033
histone modification GO:0016570 251 0.032
cellular response to organonitrogen compound GO:0071417 124 0.032
muscle cell development GO:0055001 29 0.032
cell cycle checkpoint GO:0000075 117 0.032
nitrogen compound transport GO:0071705 191 0.031
tissue regeneration GO:0042246 3 0.031
g1 s transition of mitotic cell cycle GO:0000082 78 0.031
cellular response to oxygen containing compound GO:1901701 276 0.031
positive regulation of immune system process GO:0002684 283 0.031
defense response GO:0006952 315 0.031
regulation of rna stability GO:0043487 23 0.031
lipid localization GO:0010876 106 0.031
ras protein signal transduction GO:0007265 73 0.030
Fly
response to hormone GO:0009725 175 0.030
cell projection organization GO:0030030 252 0.030
peptidyl serine phosphorylation GO:0018105 101 0.029
positive regulation of cell death GO:0010942 263 0.029
regulation of cell projection organization GO:0031344 107 0.029
oocyte development GO:0048599 1 0.028
positive regulation of immune response GO:0050778 159 0.028
protein catabolic process GO:0030163 325 0.028
response to peptide hormone GO:0043434 61 0.028
mitotic sister chromatid segregation GO:0000070 53 0.028
regulation of cell development GO:0060284 161 0.028
cellular amine metabolic process GO:0044106 41 0.028
mrna processing GO:0006397 133 0.027
immune response GO:0006955 307 0.027
peptidyl serine modification GO:0018209 106 0.026
response to oxygen containing compound GO:1901700 369 0.026
establishment of protein localization to membrane GO:0090150 121 0.026
rna splicing via transesterification reactions GO:0000375 90 0.026
rrna processing GO:0006364 35 0.026
regulation of chromosome segregation GO:0051983 44 0.025
negative regulation of intracellular signal transduction GO:1902532 183 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.025
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
anion transport GO:0006820 161 0.025
regulation of neuron projection development GO:0010975 57 0.025
mrna splicing via spliceosome GO:0000398 89 0.025
membrane organization GO:0061024 292 0.024
cellular modified amino acid metabolic process GO:0006575 64 0.024
metaphase anaphase transition of cell cycle GO:0044784 21 0.024
leukocyte activation GO:0045321 164 0.024
regulation of dendritic spine development GO:0060998 5 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.023
negative regulation of cell differentiation GO:0045596 171 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
rna catabolic process GO:0006401 71 0.023
innate immune response GO:0045087 178 0.022
regulation of nervous system development GO:0051960 88 0.022
protein acylation GO:0043543 138 0.022
hemopoiesis GO:0030097 180 0.022
response to cytokine GO:0034097 232 0.022
establishment or maintenance of cell polarity GO:0007163 31 0.022
Fly
developmental cell growth GO:0048588 18 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.021
regulation of protein transport GO:0051223 213 0.021
interspecies interaction between organisms GO:0044419 156 0.021
regulation of developmental growth GO:0048638 30 0.021
Fly
regulation of extent of cell growth GO:0061387 9 0.021
system process GO:0003008 349 0.021
regionalization GO:0003002 29 0.021
Fly
intrinsic apoptotic signaling pathway GO:0097193 127 0.020
cell morphogenesis GO:0000902 296 0.020
positive regulation of developmental growth GO:0048639 16 0.020
regulation of cell cycle phase transition GO:1901987 126 0.020
single organism reproductive process GO:0044702 98 0.020
Fly
regulation of mrna splicing via spliceosome GO:0048024 32 0.020
mitotic spindle elongation GO:0000022 4 0.019
negative regulation of catabolic process GO:0009895 104 0.019
negative regulation of cell death GO:0060548 345 0.019
regulation of immune response GO:0050776 201 0.019
regulation of t cell activation GO:0050863 77 0.019
rna export from nucleus GO:0006405 33 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
negative regulation of cytoplasmic transport GO:1903650 46 0.019
regulation of lymphocyte mediated immunity GO:0002706 33 0.018
carboxylic acid biosynthetic process GO:0046394 97 0.018
intracellular mrna localization GO:0008298 1 0.018
regulation of intracellular protein transport GO:0033157 123 0.018
apoptotic signaling pathway GO:0097190 268 0.018
cell cycle g1 s phase transition GO:0044843 80 0.018
negative regulation of transferase activity GO:0051348 124 0.017
regulation of mrna stability GO:0043488 23 0.017
regulation of multi organism process GO:0043900 157 0.017
stem cell maintenance GO:0019827 19 0.017
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.017
nuclear division GO:0000280 128 0.017
chromosome segregation GO:0007059 114 0.017
secretion by cell GO:0032940 226 0.017
covalent chromatin modification GO:0016569 254 0.017
regulation of autophagy GO:0010506 52 0.017
growth GO:0040007 202 0.017
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.017
regulation of rna splicing GO:0043484 62 0.017
t cell activation GO:0042110 99 0.017
lipid metabolic process GO:0006629 381 0.016
multi organism cellular process GO:0044764 156 0.016
negative regulation of protein processing GO:0010955 142 0.016
sex determination GO:0007530 3 0.016
dendritic spine organization GO:0097061 4 0.016
behavior GO:0007610 112 0.016
negative regulation of kinase activity GO:0033673 106 0.016
detection of stimulus GO:0051606 85 0.016
developmental process involved in reproduction GO:0003006 66 0.016
Fly
rna 5 end processing GO:0000966 2 0.015
mitotic sister chromatid separation GO:0051306 18 0.015
signal transduction by p53 class mediator GO:0072331 72 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
positive regulation of cell cycle GO:0045787 140 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.015
rna 3 end processing GO:0031123 35 0.015
oocyte differentiation GO:0009994 2 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.015
single fertilization GO:0007338 11 0.015
rna splicing GO:0008380 131 0.015
posttranscriptional gene silencing GO:0016441 25 0.014
protein localization to membrane GO:0072657 160 0.014
embryonic organ development GO:0048568 36 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
dna conformation change GO:0071103 113 0.014
embryo development ending in birth or egg hatching GO:0009792 34 0.014
nuclear migration GO:0007097 1 0.014
regulation of leukocyte activation GO:0002694 115 0.014
reproductive process GO:0022414 106 0.014
Fly
positive regulation of dendrite morphogenesis GO:0050775 3 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
positive regulation of cellular component biogenesis GO:0044089 158 0.014
regulation of protein catabolic process GO:0042176 155 0.014
tripartite regional subdivision GO:0007351 2 0.014
primary mirna processing GO:0031053 3 0.013
positive regulation of transferase activity GO:0051347 227 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.013
muscle structure development GO:0061061 98 0.013
positive regulation of mitotic cell cycle GO:0045931 60 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
positive regulation of cell activation GO:0050867 81 0.013
organelle assembly GO:0070925 176 0.013
nuclear transcribed mrna catabolic process GO:0000956 48 0.013
regulation of lymphocyte activation GO:0051249 103 0.013
regulation of mitotic sister chromatid separation GO:0010965 27 0.013
ossification GO:0001503 121 0.013
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.013
cell part morphogenesis GO:0032990 137 0.012
negative regulation of transport GO:0051051 176 0.012
male gamete generation GO:0048232 22 0.012
vesicle mediated transport GO:0016192 371 0.012
dna repair GO:0006281 198 0.012
regulation of nucleocytoplasmic transport GO:0046822 98 0.012
circulatory system development GO:0072359 262 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
positive regulation of gamma delta t cell activation GO:0046645 1 0.012
chromatin assembly GO:0031497 61 0.012
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.012
striated muscle cell development GO:0055002 27 0.012
rhythmic process GO:0048511 31 0.012
mrna catabolic process GO:0006402 56 0.012
metaphase plate congression GO:0051310 18 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
cellular response to dsrna GO:0071359 19 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.011
segmentation GO:0035282 4 0.011
regulation of golgi to plasma membrane protein transport GO:0042996 3 0.011
nucleus organization GO:0006997 28 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
urogenital system development GO:0001655 65 0.011
negative regulation of cell cycle GO:0045786 193 0.011
negative regulation of viral process GO:0048525 66 0.011
single organism cellular localization GO:1902580 332 0.011
neuron projection development GO:0031175 106 0.011
regulation of cellular response to stress GO:0080135 244 0.011
leukocyte mediated immunity GO:0002443 59 0.011
positive regulation of protein complex assembly GO:0031334 86 0.010
negative regulation of peptidase activity GO:0010466 91 0.010
maturation of 5 8s rrna GO:0000460 8 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
spindle elongation GO:0051231 4 0.010
sleep GO:0030431 2 0.010
protein glycosylation GO:0006486 62 0.010
regulation of bone resorption GO:0045124 4 0.010

G3BP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.075
eye and adnexa disease DOID:1492 150 0.075
nervous system disease DOID:863 431 0.075
retinal disease DOID:5679 118 0.052
retinal degeneration DOID:8466 89 0.052
eye disease DOID:5614 149 0.052
central nervous system disease DOID:331 186 0.037
neurodegenerative disease DOID:1289 102 0.037
glaucoma DOID:1686 8 0.029