Homo sapiens

0 known processes

CETN1

centrin, EF-hand protein, 1

(Aliases: CETN,CEN1)

CETN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 338 0.173
g protein coupled receptor signaling pathway GO:0007186 207 0.113
regulation of cellular ketone metabolic process GO:0010565 50 0.094
regulation of cellular amino acid metabolic process GO:0006521 6 0.087
amine metabolic process GO:0009308 44 0.080
cellular amino acid metabolic process GO:0006520 116 0.077
positive regulation of cellular amine metabolic process GO:0033240 7 0.074
regulation of cellular component movement GO:0051270 334 0.070
cellular macromolecule catabolic process GO:0044265 380 0.062
regulation of cell motility GO:2000145 299 0.062
chemical homeostasis GO:0048878 306 0.061
cellular amine metabolic process GO:0044106 41 0.059
cation transport GO:0006812 331 0.057
regulation of cellular amine metabolic process GO:0033238 11 0.054
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
system process GO:0003008 349 0.052
cellular ketone metabolic process GO:0042180 80 0.050
post embryonic development GO:0009791 2 0.050
negative regulation of protein metabolic process GO:0051248 391 0.050
protein modification by small protein conjugation GO:0032446 342 0.049
regulation of locomotion GO:0040012 329 0.046
protein catabolic process GO:0030163 325 0.046
regulation of cell cycle GO:0051726 393 0.045
response to oxygen containing compound GO:1901700 369 0.043
chromatin modification GO:0016568 298 0.041
negative regulation of catalytic activity GO:0043086 335 0.041
regulation of protein localization GO:0032880 296 0.041
protein processing GO:0016485 226 0.041
protein ubiquitination GO:0016567 314 0.040
immune response GO:0006955 307 0.040
negative regulation of multicellular organismal process GO:0051241 317 0.039
multicellular organismal aging GO:0010259 3 0.038
mitotic cell cycle GO:0000278 326 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.038
regulation of cell migration GO:0030334 289 0.038
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.037
regulation of proteolysis GO:0030162 293 0.036
protein maturation GO:0051604 233 0.035
enzyme linked receptor protein signaling pathway GO:0007167 303 0.035
negative regulation of proteolysis GO:0045861 132 0.035
female gamete generation GO:0007292 2 0.035
response to growth factor GO:0070848 205 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.033
negative regulation of protein processing GO:0010955 142 0.033
regulation of protein processing GO:0070613 150 0.033
negative regulation of protein maturation GO:1903318 142 0.032
negative regulation of cellular component organization GO:0051129 235 0.032
actin filament based process GO:0030029 224 0.031
cardiovascular system development GO:0072358 262 0.031
negative regulation of locomotion GO:0040013 118 0.030
chromatin organization GO:0006325 351 0.030
regulation of transferase activity GO:0051338 355 0.030
epithelium development GO:0060429 227 0.030
regulation of anatomical structure morphogenesis GO:0022603 286 0.030
regulation of protein maturation GO:1903317 150 0.029
negative regulation of cell motility GO:2000146 104 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
oogenesis GO:0048477 2 0.029
cellular component morphogenesis GO:0032989 314 0.028
negative regulation of developmental process GO:0051093 247 0.028
negative regulation of apoptotic process GO:0043066 316 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
cellular homeostasis GO:0019725 196 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.027
negative regulation of cell death GO:0060548 345 0.027
lipid metabolic process GO:0006629 381 0.027
response to hormone GO:0009725 175 0.027
inorganic ion transmembrane transport GO:0098660 231 0.027
determination of adult lifespan GO:0008340 2 0.027
cellular response to dna damage stimulus GO:0006974 379 0.027
cellular protein catabolic process GO:0044257 261 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
transmembrane transport GO:0055085 399 0.026
modification dependent macromolecule catabolic process GO:0043632 212 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
modification dependent protein catabolic process GO:0019941 209 0.026
circulatory system development GO:0072359 262 0.026
cardiac muscle contraction GO:0060048 34 0.026
response to abiotic stimulus GO:0009628 336 0.026
muscle system process GO:0003012 81 0.026
organonitrogen compound biosynthetic process GO:1901566 200 0.026
single organism cellular localization GO:1902580 332 0.026
purine containing compound catabolic process GO:0072523 411 0.025
biological adhesion GO:0022610 331 0.025
regulation of protein catabolic process GO:0042176 155 0.025
negative regulation of organelle organization GO:0010639 126 0.025
vesicle mediated transport GO:0016192 371 0.025
cell morphogenesis GO:0000902 296 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
negative regulation of programmed cell death GO:0043069 321 0.024
positive regulation of hydrolase activity GO:0051345 331 0.024
negative regulation of catabolic process GO:0009895 104 0.024
neurological system process GO:0050877 163 0.024
mitotic cell cycle process GO:1903047 286 0.024
cytoplasmic transport GO:0016482 379 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
regulation of cell cycle process GO:0010564 266 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.023
ribonucleoside catabolic process GO:0042454 406 0.023
proteasomal protein catabolic process GO:0010498 176 0.023
cell division GO:0051301 168 0.023
vasculature development GO:0001944 181 0.023
carbohydrate metabolic process GO:0005975 207 0.023
cell growth GO:0016049 160 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
cellular chemical homeostasis GO:0055082 180 0.023
muscle contraction GO:0006936 73 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
covalent chromatin modification GO:0016569 254 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.022
regulation of cell division GO:0051302 116 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
cation homeostasis GO:0055080 189 0.022
regulation of kinase activity GO:0043549 314 0.022
negative regulation of cell migration GO:0030336 102 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
regulation of protein kinase activity GO:0045859 289 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
nucleotide catabolic process GO:0009166 408 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
negative regulation of cell cycle GO:0045786 193 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
positive regulation of cell death GO:0010942 263 0.021
regeneration GO:0031099 4 0.021
cardiac muscle cell contraction GO:0086003 4 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
metal ion transport GO:0030001 272 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
positive regulation of transport GO:0051050 336 0.021
mapk cascade GO:0000165 288 0.021
purine nucleoside catabolic process GO:0006152 398 0.021
nucleoside catabolic process GO:0009164 408 0.021
organophosphate catabolic process GO:0046434 430 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
negative regulation of protein modification process GO:0031400 200 0.021
cellular lipid metabolic process GO:0044255 303 0.021
positive regulation of locomotion GO:0040017 186 0.020
histone modification GO:0016570 251 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
blood vessel development GO:0001568 172 0.020
defense response GO:0006952 315 0.020
interspecies interaction between organisms GO:0044419 156 0.020
circadian behavior GO:0048512 2 0.020
mitotic cell cycle phase transition GO:0044772 162 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
organ morphogenesis GO:0009887 147 0.020
cation transmembrane transport GO:0098655 238 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
rhythmic behavior GO:0007622 2 0.020
negative regulation of cellular component movement GO:0051271 106 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
multi organism cellular process GO:0044764 156 0.020
response to external biotic stimulus GO:0043207 261 0.020
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.019
regulation of protein ubiquitination GO:0031396 95 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
maintenance of location GO:0051235 112 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
single organism membrane organization GO:0044802 268 0.019
memory GO:0007613 3 0.019
response to lipid GO:0033993 206 0.019
response to wounding GO:0009611 168 0.018
organophosphate biosynthetic process GO:0090407 163 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
regulation of response to external stimulus GO:0032101 222 0.018
intracellular protein transport GO:0006886 270 0.018
nervous system development GO:0007399 293 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
epithelial cell differentiation GO:0030855 141 0.018
regulation of muscle system process GO:0090257 53 0.018
rna processing GO:0006396 255 0.017
negative regulation of transferase activity GO:0051348 124 0.017
response to organic cyclic compound GO:0014070 204 0.017
cell cycle phase transition GO:0044770 173 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
negative regulation of cellular catabolic process GO:0031330 83 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
regulation of cell differentiation GO:0045595 393 0.017
membrane organization GO:0061024 292 0.017
protein localization to organelle GO:0033365 280 0.017
cellular ion homeostasis GO:0006873 168 0.017
positive regulation of kinase activity GO:0033674 204 0.017
regulation of cellular protein catabolic process GO:1903362 96 0.017
striated muscle contraction GO:0006941 52 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
regulation of blood circulation GO:1903522 59 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
ion homeostasis GO:0050801 230 0.017
actin mediated cell contraction GO:0070252 12 0.017
actin filament based movement GO:0030048 17 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
neuromuscular junction development GO:0007528 3 0.017
cellular metal ion homeostasis GO:0006875 146 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
regulation of nucleotide catabolic process GO:0030811 205 0.016
positive regulation of catabolic process GO:0009896 310 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
regulation of immune response GO:0050776 201 0.016
cellular response to oxygen containing compound GO:1901701 276 0.016
inorganic cation transmembrane transport GO:0098662 194 0.016
positive regulation of cytokine production GO:0001819 167 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.016
organic anion transport GO:0015711 103 0.016
regulation of heart contraction GO:0008016 50 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
hindbrain development GO:0030902 3 0.016
cytokine production GO:0001816 247 0.016
protein modification by small protein removal GO:0070646 92 0.016
immune system development GO:0002520 195 0.016
regulation of protein transport GO:0051223 213 0.016
regulation of proteasomal protein catabolic process GO:0061136 87 0.015
immune effector process GO:0002252 159 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
apoptotic signaling pathway GO:0097190 268 0.015
divalent inorganic cation transport GO:0072511 158 0.015
positive regulation of immune system process GO:0002684 283 0.015
negative regulation of transport GO:0051051 176 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
regulation of nucleoside metabolic process GO:0009118 209 0.015
mitotic nuclear division GO:0007067 119 0.015
spermatid differentiation GO:0048515 4 0.015
blood circulation GO:0008015 113 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
regulation of vasculature development GO:1901342 97 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
positive regulation of cell motility GO:2000147 177 0.015
regulation of chromosome organization GO:0033044 103 0.015
regulation of mapk cascade GO:0043408 262 0.015
secretion by cell GO:0032940 226 0.015
reactive nitrogen species metabolic process GO:2001057 3 0.015
cell adhesion GO:0007155 325 0.015
segmentation GO:0035282 4 0.015
organelle fission GO:0048285 149 0.015
regulation of cell adhesion GO:0030155 166 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.015
regulation of cytokine production GO:0001817 232 0.015
cellular cation homeostasis GO:0030003 163 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
small gtpase mediated signal transduction GO:0007264 78 0.014
ras protein signal transduction GO:0007265 73 0.014
positive regulation of developmental process GO:0051094 314 0.014
sequestering of calcium ion GO:0051208 17 0.014
regulation of intracellular transport GO:0032386 195 0.014
regulation of secretion by cell GO:1903530 177 0.014
cell cell signaling GO:0007267 155 0.014
leukocyte migration GO:0050900 107 0.014
regulation of angiogenesis GO:0045765 92 0.014
regulation of ion transport GO:0043269 189 0.014
nerve development GO:0021675 4 0.014
chemotaxis GO:0006935 157 0.014
dna repair GO:0006281 198 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
organ formation GO:0048645 3 0.014
cyclic nucleotide metabolic process GO:0009187 82 0.014
metencephalon development GO:0022037 2 0.014
positive regulation of cell cycle GO:0045787 140 0.014
sensory perception GO:0007600 103 0.014
dephosphorylation GO:0016311 209 0.014
regulation of cell growth GO:0001558 135 0.014
blastoderm segmentation GO:0007350 2 0.014
angiogenesis GO:0001525 147 0.014
calcium ion homeostasis GO:0055074 122 0.014
positive regulation of cell migration GO:0030335 172 0.013
protein oligomerization GO:0051259 173 0.013
cellular calcium ion homeostasis GO:0006874 117 0.013
mrna metabolic process GO:0016071 175 0.013
negative regulation of synaptic transmission GO:0050805 2 0.013
regulation of cellular response to stress GO:0080135 244 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.013
innate immune response GO:0045087 178 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
cell cycle checkpoint GO:0000075 117 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
microtubule based process GO:0007017 210 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
epithelial cell migration GO:0010631 119 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of peptidase activity GO:0052547 180 0.013
secretion GO:0046903 254 0.013
atp metabolic process GO:0046034 176 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
cell projection organization GO:0030030 252 0.013
spermatid development GO:0007286 4 0.013
regulation of protein stability GO:0031647 87 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
positive regulation of transferase activity GO:0051347 227 0.013
regulation of hormone secretion GO:0046883 57 0.013
ossification GO:0001503 121 0.013
monovalent inorganic cation transport GO:0015672 128 0.013
tachykinin receptor signaling pathway GO:0007217 3 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
ameboidal type cell migration GO:0001667 135 0.012
rna splicing GO:0008380 131 0.012
tissue morphogenesis GO:0048729 96 0.012
positive regulation of cell development GO:0010720 92 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
protein localization to membrane GO:0072657 160 0.012
response to lithium ion GO:0010226 2 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.012
protein deubiquitination GO:0016579 79 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
viral process GO:0016032 146 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
cell projection morphogenesis GO:0048858 129 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
regulation of dna metabolic process GO:0051052 153 0.012
head development GO:0060322 108 0.012
dna replication GO:0006260 116 0.012
cell development GO:0048468 328 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
anterior posterior axis specification GO:0009948 2 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
response to decreased oxygen levels GO:0036293 96 0.012
nitrogen compound transport GO:0071705 191 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
regulation of gtpase activity GO:0043087 180 0.012
cell part morphogenesis GO:0032990 137 0.012
cellular potassium ion transport GO:0071804 60 0.012
response to axon injury GO:0048678 1 0.012
sensory perception of smell GO:0007608 2 0.012
negative regulation of protein catabolic process GO:0042177 59 0.012
organelle assembly GO:0070925 176 0.012
response to other organism GO:0051707 261 0.012
sequestering of metal ion GO:0051238 24 0.012
heart morphogenesis GO:0003007 48 0.012
response to activity GO:0014823 0 0.012
regulation of muscle contraction GO:0006937 45 0.012
behavior GO:0007610 112 0.012
regulation of hormone levels GO:0010817 125 0.012
regulation of system process GO:0044057 101 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
epithelium migration GO:0090132 119 0.012
regulation of cellular response to growth factor stimulus GO:0090287 76 0.012
regulation of growth GO:0040008 165 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
protein secretion GO:0009306 98 0.012
oocyte differentiation GO:0009994 2 0.011
oocyte development GO:0048599 1 0.011
cellular response to cytokine stimulus GO:0071345 181 0.011
regulation of secretion GO:0051046 194 0.011
protein targeting GO:0006605 187 0.011
response to biotic stimulus GO:0009607 276 0.011
cerebellum development GO:0021549 2 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
response to cytokine GO:0034097 232 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
response to fungus GO:0009620 4 0.011
protein localization to nucleus GO:0034504 136 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
response to nitrogen compound GO:1901698 184 0.011
regulation of transmembrane transport GO:0034762 139 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
chromosome segregation GO:0007059 114 0.011
nucleotide biosynthetic process GO:0009165 109 0.011
cellular response to lipid GO:0071396 127 0.011
regulation of homeostatic process GO:0032844 121 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
nuclear division GO:0000280 128 0.011
regulation of epithelial cell migration GO:0010632 93 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
negative regulation of cytokine production GO:0001818 82 0.011
gtp metabolic process GO:0046039 239 0.011
cell matrix adhesion GO:0007160 85 0.011
growth GO:0040007 202 0.011
regulation of metal ion transport GO:0010959 120 0.011
regulation of mitosis GO:0007088 63 0.011
gtp catabolic process GO:0006184 237 0.011
cellular protein complex assembly GO:0043623 188 0.011
purine nucleotide biosynthetic process GO:0006164 84 0.011
receptor metabolic process GO:0043112 81 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
tissue migration GO:0090130 119 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
associative learning GO:0008306 1 0.010
response to hypoxia GO:0001666 96 0.010
negative regulation of growth GO:0045926 97 0.010
motor neuron axon guidance GO:0008045 2 0.010
regulation of ion transmembrane transport GO:0034765 132 0.010
cell projection assembly GO:0030031 126 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.010
regulation of canonical wnt signaling pathway GO:0060828 88 0.010
regulation of binding GO:0051098 111 0.010
actin cytoskeleton organization GO:0030036 207 0.010
negative regulation of cell cycle phase transition GO:1901988 89 0.010
rho protein signal transduction GO:0007266 26 0.010
microtubule cytoskeleton organization GO:0000226 176 0.010
calcium ion transport GO:0006816 147 0.010
glycoprotein metabolic process GO:0009100 110 0.010
multicellular organismal signaling GO:0035637 34 0.010
regulation of epithelial cell proliferation GO:0050678 113 0.010
atp catabolic process GO:0006200 157 0.010
positive regulation of organelle organization GO:0010638 195 0.010
regulation of protein complex assembly GO:0043254 147 0.010
mrna processing GO:0006397 133 0.010
viral life cycle GO:0019058 132 0.010
retinal ganglion cell axon guidance GO:0031290 2 0.010
mating GO:0007618 1 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
regulation of response to wounding GO:1903034 101 0.010

CETN1 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.032
nervous system disease DOID:863 431 0.032
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.019
retinal disease DOID:5679 118 0.019
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
disease of metabolism DOID:0014667 295 0.015
central nervous system disease DOID:331 186 0.013
musculoskeletal system disease DOID:17 223 0.013
organ system cancer DOID:0050686 164 0.013
bone disease DOID:0080001 88 0.010
connective tissue disease DOID:65 109 0.010