Homo sapiens

32 known processes

WDR6

WD repeat domain 6

(Aliases: FLJ10218,MGC142027,FLJ52552,FLJ56107,MGC126756)

WDR6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecular complex assembly GO:0034622 324 0.370
nucleoside catabolic process GO:0009164 408 0.326
small gtpase mediated signal transduction GO:0007264 78 0.276
gtp metabolic process GO:0046039 239 0.262
regulation of nucleoside metabolic process GO:0009118 209 0.239
regulation of gtpase activity GO:0043087 180 0.213
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.212
guanosine containing compound catabolic process GO:1901069 239 0.211
purine nucleoside triphosphate catabolic process GO:0009146 392 0.209
ribonucleoside triphosphate metabolic process GO:0009199 412 0.203
guanosine containing compound metabolic process GO:1901068 244 0.201
positive regulation of ras gtpase activity GO:0032320 117 0.191
glycosyl compound catabolic process GO:1901658 413 0.174
gtp catabolic process GO:0006184 237 0.172
purine ribonucleoside catabolic process GO:0046130 398 0.170
rho protein signal transduction GO:0007266 26 0.169
purine containing compound catabolic process GO:0072523 411 0.169
organophosphate catabolic process GO:0046434 430 0.166
positive regulation of catabolic process GO:0009896 310 0.162
positive regulation of gtp catabolic process GO:0033126 166 0.162
purine ribonucleoside metabolic process GO:0046128 437 0.161
purine nucleoside catabolic process GO:0006152 398 0.158
regulation of gtp catabolic process GO:0033124 180 0.157
nucleoside triphosphate catabolic process GO:0009143 394 0.156
purine ribonucleotide catabolic process GO:0009154 404 0.148
purine nucleoside triphosphate metabolic process GO:0009144 412 0.139
ribonucleoside catabolic process GO:0042454 406 0.136
post embryonic development GO:0009791 2 0.134
ribonucleoside triphosphate catabolic process GO:0009203 391 0.131
nucleoside triphosphate metabolic process GO:0009141 422 0.128
purine nucleotide catabolic process GO:0006195 405 0.126
positive regulation of nucleotide catabolic process GO:0030813 185 0.125
cell projection assembly GO:0030031 126 0.125
protein modification by small protein conjugation GO:0032446 342 0.125
positive regulation of gtpase activity GO:0043547 166 0.125
ribonucleotide catabolic process GO:0009261 405 0.123
regulation of anatomical structure morphogenesis GO:0022603 286 0.120
nucleotide catabolic process GO:0009166 408 0.117
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.117
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.110
positive regulation of cellular component organization GO:0051130 376 0.109
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.107
regulation of cell projection organization GO:0031344 107 0.106
regulation of rho gtpase activity GO:0032319 66 0.105
regulation of purine nucleotide catabolic process GO:0033121 205 0.103
positive regulation of nucleotide metabolic process GO:0045981 230 0.102
regulation of small gtpase mediated signal transduction GO:0051056 156 0.099
regulation of nucleotide catabolic process GO:0030811 205 0.097
actin filament based process GO:0030029 224 0.095
regulation of purine nucleotide metabolic process GO:1900542 264 0.090
regulation of ras protein signal transduction GO:0046578 155 0.090
positive regulation of cellular catabolic process GO:0031331 284 0.086
regulation of actin filament polymerization GO:0030833 50 0.086
positive regulation of hydrolase activity GO:0051345 331 0.084
actin cytoskeleton organization GO:0030036 207 0.083
regulation of cellular ketone metabolic process GO:0010565 50 0.083
positive regulation of cellular component biogenesis GO:0044089 158 0.083
cellular component morphogenesis GO:0032989 314 0.080
actin filament organization GO:0007015 128 0.080
segmentation GO:0035282 4 0.079
multicellular organismal aging GO:0010259 3 0.077
regulation of nucleotide metabolic process GO:0006140 269 0.074
regulation of cytoskeleton organization GO:0051493 177 0.073
regulation of cell morphogenesis GO:0022604 153 0.072
sex determination GO:0007530 3 0.070
cellular protein complex assembly GO:0043623 188 0.068
positive regulation of nucleoside metabolic process GO:0045979 186 0.068
regulation of rho protein signal transduction GO:0035023 79 0.065
cell morphogenesis GO:0000902 296 0.065
ras protein signal transduction GO:0007265 73 0.063
cellular ketone metabolic process GO:0042180 80 0.062
positive regulation of actin filament polymerization GO:0030838 38 0.062
regulation of protein polymerization GO:0032271 63 0.059
somatic stem cell division GO:0048103 1 0.058
amine metabolic process GO:0009308 44 0.058
regulation of actin filament based process GO:0032970 141 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
positive regulation of cell projection organization GO:0031346 64 0.056
protein ubiquitination GO:0016567 314 0.056
cell projection organization GO:0030030 252 0.054
cellular amine metabolic process GO:0044106 41 0.054
cytoplasmic transport GO:0016482 379 0.053
cellular amino acid metabolic process GO:0006520 116 0.052
oogenesis GO:0048477 2 0.050
actin filament polymerization GO:0030041 45 0.050
protein polyubiquitination GO:0000209 110 0.050
positive regulation of protein polymerization GO:0032273 45 0.049
regulation of cellular component size GO:0032535 82 0.047
regulation of actin cytoskeleton organization GO:0032956 116 0.047
female gamete generation GO:0007292 2 0.046
protein polymerization GO:0051258 71 0.046
positive regulation of rho gtpase activity GO:0032321 56 0.046
actin polymerization or depolymerization GO:0008154 56 0.045
intrinsic apoptotic signaling pathway GO:0097193 127 0.044
regulation of protein complex assembly GO:0043254 147 0.044
regulation of locomotion GO:0040012 329 0.043
positive regulation of pseudopodium assembly GO:0031274 7 0.043
determination of adult lifespan GO:0008340 2 0.043
regulation of cellular component biogenesis GO:0044087 281 0.043
apoptotic signaling pathway GO:0097190 268 0.043
positive regulation of cytoskeleton organization GO:0051495 83 0.043
blastoderm segmentation GO:0007350 2 0.042
cell fate determination GO:0001709 3 0.042
regulation of cellular amino acid metabolic process GO:0006521 6 0.040
positive regulation of protein complex assembly GO:0031334 86 0.040
carbohydrate metabolic process GO:0005975 207 0.038
negative regulation of apoptotic signaling pathway GO:2001234 97 0.038
regulation of cellular amine metabolic process GO:0033238 11 0.037
anterior posterior axis specification GO:0009948 2 0.036
regulation of anatomical structure size GO:0090066 101 0.036
pseudopodium organization GO:0031268 8 0.036
regulation of cell differentiation GO:0045595 393 0.035
lipid metabolic process GO:0006629 381 0.035
negative regulation of cell death GO:0060548 345 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
cell growth GO:0016049 160 0.033
positive regulation of organelle organization GO:0010638 195 0.032
chemical homeostasis GO:0048878 306 0.032
cellular lipid metabolic process GO:0044255 303 0.031
hemopoiesis GO:0030097 180 0.031
negative regulation of multicellular organismal process GO:0051241 317 0.031
regulation of cell cycle GO:0051726 393 0.031
neuroblast proliferation GO:0007405 4 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
immune response GO:0006955 307 0.029
asymmetric stem cell division GO:0098722 1 0.028
nervous system development GO:0007399 293 0.028
regulation of kinase activity GO:0043549 314 0.028
histone modification GO:0016570 251 0.028
single organism carbohydrate metabolic process GO:0044723 193 0.027
positive regulation of cell death GO:0010942 263 0.027
single organism cellular localization GO:1902580 332 0.027
vasculature development GO:0001944 181 0.027
enzyme linked receptor protein signaling pathway GO:0007167 303 0.027
negative regulation of apoptotic process GO:0043066 316 0.027
nucleocytoplasmic transport GO:0006913 176 0.026
asymmetric neuroblast division GO:0055059 1 0.026
anterior posterior axis specification embryo GO:0008595 2 0.026
spermatid development GO:0007286 4 0.026
biological adhesion GO:0022610 331 0.025
oocyte differentiation GO:0009994 2 0.025
negative regulation of developmental process GO:0051093 247 0.025
oocyte development GO:0048599 1 0.025
regulation of protein kinase activity GO:0045859 289 0.024
tripartite regional subdivision GO:0007351 2 0.024
rna processing GO:0006396 255 0.024
regulation of cell cycle process GO:0010564 266 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
positive regulation of programmed cell death GO:0043068 249 0.024
mrna metabolic process GO:0016071 175 0.024
epithelium development GO:0060429 227 0.023
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.023
immune system development GO:0002520 195 0.023
regulation of wnt signaling pathway GO:0030111 123 0.022
spermatid differentiation GO:0048515 4 0.022
positive regulation of kinase activity GO:0033674 204 0.022
protein oligomerization GO:0051259 173 0.021
negative regulation of protein metabolic process GO:0051248 391 0.021
embryo development GO:0009790 123 0.021
peptidyl tyrosine phosphorylation GO:0018108 170 0.021
mitotic cell cycle GO:0000278 326 0.021
positive regulation of apoptotic process GO:0043065 246 0.021
neuronal stem cell division GO:0036445 1 0.021
response to radiation GO:0009314 151 0.021
oxidation reduction process GO:0055114 396 0.020
microtubule based process GO:0007017 210 0.020
stem cell division GO:0017145 2 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
regulation of transferase activity GO:0051338 355 0.020
cellular macromolecule catabolic process GO:0044265 380 0.020
t cell differentiation in thymus GO:0033077 4 0.020
cell adhesion GO:0007155 325 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
circulatory system development GO:0072359 262 0.020
regulation of cell growth GO:0001558 135 0.020
cellular response to endogenous stimulus GO:0071495 336 0.019
vesicle mediated transport GO:0016192 371 0.019
dephosphorylation GO:0016311 209 0.019
neurogenesis GO:0022008 169 0.019
nuclear transport GO:0051169 179 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
nitrogen compound transport GO:0071705 191 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
regulation of cell migration GO:0030334 289 0.018
peripheral nervous system development GO:0007422 2 0.018
neuroblast division GO:0055057 1 0.018
memory GO:0007613 3 0.018
covalent chromatin modification GO:0016569 254 0.018
cell development GO:0048468 328 0.018
canonical wnt signaling pathway GO:0060070 116 0.018
protein catabolic process GO:0030163 325 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.018
morphogenesis of embryonic epithelium GO:0016331 4 0.018
locomotory behavior GO:0007626 1 0.018
positive regulation of protein phosphorylation GO:0001934 313 0.017
regulation of mapk cascade GO:0043408 262 0.017
chromatin organization GO:0006325 351 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
organic hydroxy compound metabolic process GO:1901615 147 0.017
cell part morphogenesis GO:0032990 137 0.017
response to nitrogen compound GO:1901698 184 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.016
hindbrain development GO:0030902 3 0.016
mrna processing GO:0006397 133 0.016
regulation of neural precursor cell proliferation GO:2000177 4 0.016
negative regulation of locomotion GO:0040013 118 0.016
lipid biosynthetic process GO:0008610 177 0.016
response to oxygen containing compound GO:1901700 369 0.016
neural tube formation GO:0001841 3 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
secretion GO:0046903 254 0.016
regulation of cellular response to stress GO:0080135 244 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.015
organelle assembly GO:0070925 176 0.015
cell projection morphogenesis GO:0048858 129 0.015
leukocyte activation GO:0045321 164 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
negative regulation of cell migration GO:0030336 102 0.015
rab protein signal transduction GO:0032482 4 0.015
regulation of immune response GO:0050776 201 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
neurological system process GO:0050877 163 0.015
cell division GO:0051301 168 0.015
positive regulation of immune system process GO:0002684 283 0.015
single organism membrane organization GO:0044802 268 0.015
mapk cascade GO:0000165 288 0.015
regulation of cell division GO:0051302 116 0.015
innate immune response GO:0045087 178 0.015
regulation of cell development GO:0060284 161 0.014
nerve development GO:0021675 4 0.014
primary neural tube formation GO:0014020 3 0.014
anatomical structure homeostasis GO:0060249 100 0.014
intracellular mrna localization GO:0008298 1 0.014
endosomal transport GO:0016197 129 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
membrane organization GO:0061024 292 0.014
response to hormone GO:0009725 175 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
rhythmic behavior GO:0007622 2 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.014
cardiovascular system development GO:0072358 262 0.014
cell cycle arrest GO:0007050 71 0.014
regeneration GO:0031099 4 0.014
negative regulation of protein modification process GO:0031400 200 0.014
catecholamine secretion GO:0050432 1 0.014
tissue homeostasis GO:0001894 63 0.013
monosaccharide metabolic process GO:0005996 74 0.013
positive regulation of transport GO:0051050 336 0.013
growth GO:0040007 202 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
regulation of intracellular transport GO:0032386 195 0.013
negative regulation of cellular component movement GO:0051271 106 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
endomembrane system organization GO:0010256 196 0.013
positive regulation of immune response GO:0050778 159 0.013
prostate gland development GO:0030850 3 0.013
wnt signaling pathway GO:0016055 156 0.013
regulation of protein transport GO:0051223 213 0.013
system process GO:0003008 349 0.013
somitogenesis GO:0001756 2 0.013
neuromuscular junction development GO:0007528 3 0.013
circadian behavior GO:0048512 2 0.013
alcohol metabolic process GO:0006066 114 0.013
response to decreased oxygen levels GO:0036293 96 0.013
regulation of protein localization GO:0032880 296 0.013
protein targeting GO:0006605 187 0.013
cellular protein catabolic process GO:0044257 261 0.013
multicellular organismal homeostasis GO:0048871 67 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
response to external biotic stimulus GO:0043207 261 0.012
maintenance of cell polarity GO:0030011 2 0.012
response to transforming growth factor beta GO:0071559 94 0.012
protein localization to organelle GO:0033365 280 0.012
stress activated protein kinase signaling cascade GO:0031098 94 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
energy homeostasis GO:0097009 3 0.012
chromatin modification GO:0016568 298 0.012
norepinephrine transport GO:0015874 1 0.012
actin filament based movement GO:0030048 17 0.012
small molecule biosynthetic process GO:0044283 157 0.012
long term memory GO:0007616 2 0.012
regulation of multi organism process GO:0043900 157 0.012
neuron development GO:0048666 113 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
intracellular protein transport GO:0006886 270 0.012
positive regulation of developmental process GO:0051094 314 0.012
dna repair GO:0006281 198 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
reproductive process GO:0022414 106 0.012
macromolecule methylation GO:0043414 97 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
response to growth factor GO:0070848 205 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
mitotic cell cycle process GO:1903047 286 0.011
neural tube closure GO:0001843 3 0.011
secretion by cell GO:0032940 226 0.011
negative regulation of transport GO:0051051 176 0.011
golgi vesicle transport GO:0048193 80 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
response to biotic stimulus GO:0009607 276 0.011
organelle localization GO:0051640 84 0.011
response to organic cyclic compound GO:0014070 204 0.011
g protein coupled receptor signaling pathway GO:0007186 207 0.011
hexose metabolic process GO:0019318 55 0.011
neuron differentiation GO:0030182 138 0.011
response to abiotic stimulus GO:0009628 336 0.011
regulation of cell motility GO:2000145 299 0.011
tissue regeneration GO:0042246 3 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
angiogenesis GO:0001525 147 0.011
regulation of dna metabolic process GO:0051052 153 0.011
positive regulation of rab gtpase activity GO:0032851 39 0.011
maintenance of location GO:0051235 112 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
defense response GO:0006952 315 0.011
compound eye development GO:0048749 1 0.011
cell activation GO:0001775 213 0.011
glycoprotein metabolic process GO:0009100 110 0.011
metencephalon development GO:0022037 2 0.011
positive regulation of locomotion GO:0040017 186 0.011
methylation GO:0032259 106 0.011
cilium morphogenesis GO:0060271 75 0.011
positive regulation of transferase activity GO:0051347 227 0.011
convergent extension GO:0060026 1 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.011
actin mediated cell contraction GO:0070252 12 0.010
phospholipid metabolic process GO:0006644 99 0.010
mitochondrion organization GO:0007005 156 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
protein maturation GO:0051604 233 0.010
blood vessel morphogenesis GO:0048514 162 0.010
inner ear morphogenesis GO:0042472 4 0.010
fatty acid metabolic process GO:0006631 115 0.010
regulation of lipid metabolic process GO:0019216 96 0.010
negative regulation of hydrolase activity GO:0051346 182 0.010
cytokinesis GO:0000910 96 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
regulation of cell adhesion GO:0030155 166 0.010
regulation of proteolysis GO:0030162 293 0.010
hematopoietic or lymphoid organ development GO:0048534 186 0.010
activation of immune response GO:0002253 114 0.010
monocarboxylic acid biosynthetic process GO:0072330 67 0.010
protein processing GO:0016485 226 0.010
golgi localization GO:0051645 4 0.010
associative learning GO:0008306 1 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.010

WDR6 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.028
sensory system disease DOID:0050155 203 0.025
nervous system disease DOID:863 431 0.025
central nervous system disease DOID:331 186 0.025
disease of cellular proliferation DOID:14566 174 0.022
muscular disease DOID:0080000 114 0.021
disease of metabolism DOID:0014667 295 0.019
cancer DOID:162 167 0.019
muscle tissue disease DOID:66 113 0.018
gastrointestinal system disease DOID:77 36 0.017
myopathy DOID:423 104 0.017
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
inherited metabolic disorder DOID:655 242 0.015
intestinal disease DOID:5295 14 0.014
organ system cancer DOID:0050686 164 0.014
brain disease DOID:936 73 0.013
muscular dystrophy DOID:9884 51 0.011