Homo sapiens

32 known processes

WDR4

WD repeat domain 4

(Aliases: TRM82)

WDR4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trna processing GO:0008033 23 0.983
trna methylation GO:0030488 7 0.890
macromolecule methylation GO:0043414 97 0.846
trna metabolic process GO:0006399 35 0.656
ncrna metabolic process GO:0034660 108 0.625
methylation GO:0032259 106 0.624
ncrna processing GO:0034470 83 0.551
rna modification GO:0009451 27 0.447
rna capping GO:0036260 10 0.388
7 methylguanosine rna capping GO:0009452 9 0.262
rna processing GO:0006396 255 0.235
post embryonic development GO:0009791 2 0.089
mitochondrion organization GO:0007005 156 0.054
cellular ketone metabolic process GO:0042180 80 0.047
cellular amino acid metabolic process GO:0006520 116 0.043
amine metabolic process GO:0009308 44 0.039
cellular macromolecular complex assembly GO:0034622 324 0.037
determination of adult lifespan GO:0008340 2 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.031
cellular amine metabolic process GO:0044106 41 0.030
multicellular organismal aging GO:0010259 3 0.029
oogenesis GO:0048477 2 0.028
Fly
cellular macromolecule catabolic process GO:0044265 380 0.027
neurogenesis GO:0022008 169 0.027
cell development GO:0048468 328 0.027
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
negative regulation of protein metabolic process GO:0051248 391 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
memory GO:0007613 3 0.025
membrane organization GO:0061024 292 0.024
cellular protein complex assembly GO:0043623 188 0.024
growth GO:0040007 202 0.024
female gamete generation GO:0007292 2 0.023
Fly
neuromuscular junction development GO:0007528 3 0.023
negative regulation of cell death GO:0060548 345 0.023
organophosphate catabolic process GO:0046434 430 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
negative regulation of apoptotic process GO:0043066 316 0.022
actin filament based process GO:0030029 224 0.022
negative regulation of catalytic activity GO:0043086 335 0.022
ras protein signal transduction GO:0007265 73 0.021
mitotic cell cycle GO:0000278 326 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
locomotory behavior GO:0007626 1 0.021
segmentation GO:0035282 4 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
regulation of proteolysis GO:0030162 293 0.020
organophosphate biosynthetic process GO:0090407 163 0.020
nucleotide catabolic process GO:0009166 408 0.020
nucleoside triphosphate catabolic process GO:0009143 394 0.019
cellular protein catabolic process GO:0044257 261 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
lipid metabolic process GO:0006629 381 0.019
vesicle mediated transport GO:0016192 371 0.019
protein localization to organelle GO:0033365 280 0.019
oxidation reduction process GO:0055114 396 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
cellular lipid metabolic process GO:0044255 303 0.019
cellular component morphogenesis GO:0032989 314 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
apoptotic signaling pathway GO:0097190 268 0.018
regulation of growth GO:0040008 165 0.018
glycosyl compound catabolic process GO:1901658 413 0.018
modification dependent macromolecule catabolic process GO:0043632 212 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
mrna metabolic process GO:0016071 175 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
positive regulation of catabolic process GO:0009896 310 0.018
system process GO:0003008 349 0.017
oocyte development GO:0048599 1 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
single organism membrane organization GO:0044802 268 0.017
cell projection organization GO:0030030 252 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
protein modification by small protein conjugation GO:0032446 342 0.017
small molecule biosynthetic process GO:0044283 157 0.017
oocyte differentiation GO:0009994 2 0.017
purine containing compound catabolic process GO:0072523 411 0.017
ribonucleotide catabolic process GO:0009261 405 0.016
negative regulation of cell cycle GO:0045786 193 0.016
protein catabolic process GO:0030163 325 0.016
dephosphorylation GO:0016311 209 0.016
regulation of cell differentiation GO:0045595 393 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
response to abiotic stimulus GO:0009628 336 0.016
nervous system development GO:0007399 293 0.016
intracellular protein transport GO:0006886 270 0.016
regulation of transferase activity GO:0051338 355 0.016
maintenance of location GO:0051235 112 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
chromatin organization GO:0006325 351 0.015
response to biotic stimulus GO:0009607 276 0.015
immune response GO:0006955 307 0.015
cell morphogenesis GO:0000902 296 0.015
regulation of cellular response to stress GO:0080135 244 0.015
protein maturation GO:0051604 233 0.015
actin filament based movement GO:0030048 17 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
cation transport GO:0006812 331 0.014
blastoderm segmentation GO:0007350 2 0.014
organelle fission GO:0048285 149 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
cell growth GO:0016049 160 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
microtubule based process GO:0007017 210 0.014
regulation of protein kinase activity GO:0045859 289 0.014
negative regulation of protein modification process GO:0031400 200 0.014
single organism cellular localization GO:1902580 332 0.014
compound eye development GO:0048749 1 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
ribonucleoside catabolic process GO:0042454 406 0.013
mitotic cell cycle process GO:1903047 286 0.013
protein localization to membrane GO:0072657 160 0.013
regeneration GO:0031099 4 0.013
metal ion transport GO:0030001 272 0.013
hindbrain development GO:0030902 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
translation GO:0006412 132 0.013
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
lipid biosynthetic process GO:0008610 177 0.013
organelle assembly GO:0070925 176 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
adult locomotory behavior GO:0008344 1 0.013
microtubule cytoskeleton organization GO:0000226 176 0.013
regulation of cell cycle GO:0051726 393 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
ion homeostasis GO:0050801 230 0.013
defense response GO:0006952 315 0.013
negative regulation of cell proliferation GO:0008285 228 0.012
organic anion transport GO:0015711 103 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
tripartite regional subdivision GO:0007351 2 0.012
regulation of protein catabolic process GO:0042176 155 0.012
cell projection assembly GO:0030031 126 0.012
protein homooligomerization GO:0051260 100 0.012
myosin filament assembly GO:0031034 2 0.012
spermatid differentiation GO:0048515 4 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
regulation of gtp catabolic process GO:0033124 180 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
myosin filament organization GO:0031033 2 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
endocytosis GO:0006897 159 0.012
positive regulation of cellular component organization GO:0051130 376 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
protein oligomerization GO:0051259 173 0.012
positive regulation of nucleoside metabolic process GO:0045979 186 0.012
positive regulation of transport GO:0051050 336 0.012
innate immune response GO:0045087 178 0.012
positive regulation of immune system process GO:0002684 283 0.012
regulation of protein maturation GO:1903317 150 0.012
rna catabolic process GO:0006401 71 0.011
ribosome biogenesis GO:0042254 48 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
chromatin modification GO:0016568 298 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
anion transport GO:0006820 161 0.011
anterior posterior axis specification GO:0009948 2 0.011
carbohydrate metabolic process GO:0005975 207 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
response to fungus GO:0009620 4 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
secretion GO:0046903 254 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
chemical homeostasis GO:0048878 306 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
protein alkylation GO:0008213 74 0.011
viral process GO:0016032 146 0.011
rna splicing GO:0008380 131 0.011
rrna processing GO:0006364 35 0.011
cell adhesion GO:0007155 325 0.011
defense response to other organism GO:0098542 129 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
cation homeostasis GO:0055080 189 0.011
maturation of ssu rrna GO:0030490 3 0.011
cellular cation homeostasis GO:0030003 163 0.011
negative regulation of protein processing GO:0010955 142 0.011
negative regulation of developmental process GO:0051093 247 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
negative regulation of transferase activity GO:0051348 124 0.011
cell part morphogenesis GO:0032990 137 0.011
negative regulation of protein maturation GO:1903318 142 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
blastocyst formation GO:0001825 3 0.010
multi organism cellular process GO:0044764 156 0.010
cellular homeostasis GO:0019725 196 0.010
protein processing GO:0016485 226 0.010
morphogenesis of embryonic epithelium GO:0016331 4 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
purine containing compound biosynthetic process GO:0072522 88 0.010
negative regulation of phosphorylation GO:0042326 174 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
transmembrane transport GO:0055085 399 0.010
rho protein signal transduction GO:0007266 26 0.010
positive regulation of organelle organization GO:0010638 195 0.010
regulation of protein localization GO:0032880 296 0.010
organic acid biosynthetic process GO:0016053 97 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
gtp metabolic process GO:0046039 239 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
metal ion homeostasis GO:0055065 169 0.010

WDR4 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.024
inherited metabolic disorder DOID:655 242 0.024
musculoskeletal system disease DOID:17 223 0.017
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
connective tissue disease DOID:65 109 0.012
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011