Homo sapiens

167 known processes

TNKS

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

(Aliases: PARP5A,TIN1,TINF1,PARPL,pART5,TNKS1,PARP-5a)

TNKS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of actin nucleation GO:0051126 3 0.808
cilium assembly GO:0042384 63 0.663
actin filament based movement GO:0030048 17 0.604
regulation of telomere maintenance via telomerase GO:0032210 6 0.572
cellular protein complex assembly GO:0043623 188 0.560
Fly
telomere maintenance via telomere lengthening GO:0010833 9 0.525
vesicle transport along actin filament GO:0030050 2 0.482
cilium organization GO:0044782 68 0.425
regulation of microtubule cytoskeleton organization GO:0070507 61 0.375
regulation of cellular component biogenesis GO:0044087 281 0.330
Fly
regulation of actin nucleation GO:0051125 10 0.295
positive regulation of organelle organization GO:0010638 195 0.291
protein polymerization GO:0051258 71 0.272
anatomical structure formation involved in morphogenesis GO:0048646 284 0.258
negative regulation of organelle organization GO:0010639 126 0.257
negative regulation of protein polymerization GO:0032272 16 0.228
regulation of microtubule based process GO:0032886 74 0.220
microtubule based process GO:0007017 210 0.218
regulation of cell cycle GO:0051726 393 0.217
microtubule polymerization or depolymerization GO:0031109 37 0.216
negative regulation of cytoskeleton organization GO:0051494 45 0.213
macromolecule glycosylation GO:0043413 63 0.208
carbohydrate metabolic process GO:0005975 207 0.198
protein ubiquitination GO:0016567 314 0.189
organelle assembly GO:0070925 176 0.181
mitotic cell cycle process GO:1903047 286 0.172
glycoprotein biosynthetic process GO:0009101 91 0.168
protein localization to chromosome telomeric region GO:0070198 6 0.167
cellular macromolecular complex assembly GO:0034622 324 0.162
Fly
negative regulation of protein metabolic process GO:0051248 391 0.160
regulation of telomere maintenance GO:0032204 13 0.158
cellular component assembly involved in morphogenesis GO:0010927 73 0.158
locomotory behavior GO:0007626 1 0.148
positive regulation of protein polymerization GO:0032273 45 0.147
actin cytoskeleton organization GO:0030036 207 0.145
post embryonic development GO:0009791 2 0.144
positive regulation of cellular component organization GO:0051130 376 0.142
protein modification by small protein conjugation GO:0032446 342 0.137
positive regulation of wnt signaling pathway GO:0030177 54 0.136
cell division GO:0051301 168 0.130
regulation of transferase activity GO:0051338 355 0.129
establishment of organelle localization GO:0051656 59 0.117
membrane budding GO:0006900 28 0.115
negative regulation of developmental process GO:0051093 247 0.113
negative regulation of cellular protein metabolic process GO:0032269 353 0.112
telomere maintenance GO:0000723 32 0.109
regulation of protein kinase activity GO:0045859 289 0.106
protein localization to organelle GO:0033365 280 0.103
positive regulation of dna metabolic process GO:0051054 73 0.100
regulation of organelle assembly GO:1902115 40 0.093
glycosylation GO:0070085 71 0.093
defense response GO:0006952 315 0.093
negative regulation of protein complex assembly GO:0031333 43 0.093
protein catabolic process GO:0030163 325 0.092
negative regulation of telomere maintenance GO:0032205 9 0.091
regulation of cytoskeleton organization GO:0051493 177 0.091
peptidyl serine modification GO:0018209 106 0.090
cellular macromolecule catabolic process GO:0044265 380 0.090
wnt signaling pathway GO:0016055 156 0.087
negative regulation of multicellular organismal process GO:0051241 317 0.086
innate immune response GO:0045087 178 0.081
positive regulation of telomere maintenance GO:0032206 4 0.078
vesicle organization GO:0016050 62 0.076
regulation of protein processing GO:0070613 150 0.075
regulation of protein polymerization GO:0032271 63 0.074
adult locomotory behavior GO:0008344 1 0.073
organic hydroxy compound metabolic process GO:1901615 147 0.073
membrane organization GO:0061024 292 0.072
regulation of microtubule polymerization GO:0031113 12 0.071
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.070
immune response GO:0006955 307 0.070
neuromuscular junction development GO:0007528 3 0.068
intracellular protein transport GO:0006886 270 0.068
protein glycosylation GO:0006486 62 0.068
protein processing GO:0016485 226 0.068
negative regulation of cellular component organization GO:0051129 235 0.066
regulation of cell cycle process GO:0010564 266 0.066
microtubule polymerization GO:0046785 18 0.066
cell projection assembly GO:0030031 126 0.065
modification dependent protein catabolic process GO:0019941 209 0.063
regulation of proteasomal protein catabolic process GO:0061136 87 0.063
actin filament organization GO:0007015 128 0.060
canonical wnt signaling pathway GO:0060070 116 0.060
regulation of cellular amine metabolic process GO:0033238 11 0.058
neurological system process GO:0050877 163 0.058
mitotic nuclear division GO:0007067 119 0.057
organelle localization GO:0051640 84 0.057
protein adp ribosylation GO:0006471 9 0.057
positive regulation of cellular component biogenesis GO:0044089 158 0.056
chromosome segregation GO:0007059 114 0.056
positive regulation of cell cycle GO:0045787 140 0.056
negative regulation of programmed cell death GO:0043069 321 0.056
regulation of canonical wnt signaling pathway GO:0060828 88 0.055
regulation of cellular protein catabolic process GO:1903362 96 0.054
chromatin modification GO:0016568 298 0.054
microtubule cytoskeleton organization GO:0000226 176 0.054
single organism cellular localization GO:1902580 332 0.054
actin filament based process GO:0030029 224 0.052
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.052
single organism membrane organization GO:0044802 268 0.052
mitotic sister chromatid segregation GO:0000070 53 0.051
negative regulation of telomere maintenance via telomerase GO:0032211 5 0.050
cellular ketone metabolic process GO:0042180 80 0.050
endomembrane system organization GO:0010256 196 0.049
negative regulation of glycoprotein metabolic process GO:1903019 8 0.049
cellular protein catabolic process GO:0044257 261 0.048
cell cycle g2 m phase transition GO:0044839 43 0.047
mitotic cell cycle GO:0000278 326 0.047
carbohydrate derivative biosynthetic process GO:1901137 207 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.046
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.046
regulation of actin filament based process GO:0032970 141 0.045
regulation of growth GO:0040008 165 0.045
neuroblast proliferation GO:0007405 4 0.045
negative regulation of catalytic activity GO:0043086 335 0.044
proteasomal protein catabolic process GO:0010498 176 0.044
negative regulation of protein processing GO:0010955 142 0.043
melanin metabolic process GO:0006582 1 0.042
cell fate determination GO:0001709 3 0.042
positive regulation of apoptotic process GO:0043065 246 0.042
regulation of actin cytoskeleton organization GO:0032956 116 0.041
positive regulation of protein complex assembly GO:0031334 86 0.041
nervous system development GO:0007399 293 0.041
determination of adult lifespan GO:0008340 2 0.040
regulation of proteolysis GO:0030162 293 0.040
small gtpase mediated signal transduction GO:0007264 78 0.040
negative regulation of chromosome organization GO:2001251 48 0.040
actin nucleation GO:0045010 21 0.039
centrosome organization GO:0051297 58 0.039
protein maturation GO:0051604 233 0.039
regulation of protein maturation GO:1903317 150 0.039
peptidyl serine phosphorylation GO:0018105 101 0.038
mitochondrion organization GO:0007005 156 0.037
regulation of glycoprotein metabolic process GO:1903018 19 0.037
regulation of binding GO:0051098 111 0.037
segmentation GO:0035282 4 0.037
photoreceptor cell maintenance GO:0045494 13 0.037
negative regulation of growth GO:0045926 97 0.037
sister chromatid segregation GO:0000819 54 0.037
positive regulation of programmed cell death GO:0043068 249 0.036
regulation of cell differentiation GO:0045595 393 0.036
cellular amino acid metabolic process GO:0006520 116 0.036
growth GO:0040007 202 0.035
cell part morphogenesis GO:0032990 137 0.035
mapk cascade GO:0000165 288 0.035
regulation of kinase activity GO:0043549 314 0.035
positive regulation of actin filament polymerization GO:0030838 38 0.034
positive regulation of cell differentiation GO:0045597 211 0.034
negative regulation of dna replication GO:0008156 29 0.034
somitogenesis GO:0001756 2 0.034
negative regulation of synaptic transmission GO:0050805 2 0.033
cilium morphogenesis GO:0060271 75 0.033
response to external biotic stimulus GO:0043207 261 0.033
organelle fission GO:0048285 149 0.033
positive regulation of transport GO:0051050 336 0.033
positive regulation of kinase activity GO:0033674 204 0.033
cellular response to dna damage stimulus GO:0006974 379 0.032
regulation of anatomical structure size GO:0090066 101 0.032
actin polymerization or depolymerization GO:0008154 56 0.032
cellular homeostasis GO:0019725 196 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.031
sensory perception GO:0007600 103 0.031
regulation of cell division GO:0051302 116 0.031
regulation of cellular component size GO:0032535 82 0.031
nucleoside triphosphate metabolic process GO:0009141 422 0.031
regulation of carbohydrate metabolic process GO:0006109 54 0.030
negative regulation of homeostatic process GO:0032845 59 0.030
regulation of cell projection assembly GO:0060491 47 0.030
modification dependent macromolecule catabolic process GO:0043632 212 0.030
organ morphogenesis GO:0009887 147 0.030
organelle fusion GO:0048284 36 0.030
cellular response to oxygen containing compound GO:1901701 276 0.030
regulation of centrosome cycle GO:0046605 15 0.029
axoneme assembly GO:0035082 3 0.029
regulation of actin filament length GO:0030832 56 0.029
negative regulation of nervous system development GO:0051961 28 0.029
metal ion transport GO:0030001 272 0.028
cell projection organization GO:0030030 252 0.028
dna replication GO:0006260 116 0.028
cation transport GO:0006812 331 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
regulation of actin filament polymerization GO:0030833 50 0.028
stress activated mapk cascade GO:0051403 93 0.028
single organism carbohydrate metabolic process GO:0044723 193 0.028
regulation of protein catabolic process GO:0042176 155 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
regulation of chromosome organization GO:0033044 103 0.027
cell morphogenesis GO:0000902 296 0.027
regulation of cytoplasmic transport GO:1903649 149 0.027
regulation of actin polymerization or depolymerization GO:0008064 56 0.027
regulation of cell projection organization GO:0031344 107 0.027
negative regulation of cell cycle process GO:0010948 121 0.026
negative regulation of binding GO:0051100 57 0.026
replicative cell aging GO:0001302 3 0.026
glycoprotein metabolic process GO:0009100 110 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.026
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.026
enzyme linked receptor protein signaling pathway GO:0007167 303 0.026
regulation of nuclear division GO:0051783 65 0.026
biological adhesion GO:0022610 331 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.026
cell adhesion GO:0007155 325 0.025
anatomical structure homeostasis GO:0060249 100 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
system process GO:0003008 349 0.025
actin filament polymerization GO:0030041 45 0.025
peptidyl threonine modification GO:0018210 45 0.025
mitotic cell cycle checkpoint GO:0007093 68 0.025
regulation of protein binding GO:0043393 66 0.025
oocyte differentiation GO:0009994 2 0.025
ras protein signal transduction GO:0007265 73 0.025
regulation of anatomical structure morphogenesis GO:0022603 286 0.025
regulation of homeostatic process GO:0032844 121 0.025
central nervous system development GO:0007417 123 0.024
regulation of nervous system development GO:0051960 88 0.024
rna dependent dna replication GO:0006278 16 0.024
protein targeting GO:0006605 187 0.024
multicellular organismal aging GO:0010259 3 0.024
response to growth factor GO:0070848 205 0.024
negative regulation of protein modification process GO:0031400 200 0.024
cardiovascular system development GO:0072358 262 0.024
metencephalon development GO:0022037 2 0.024
positive regulation of developmental process GO:0051094 314 0.024
regulation of establishment of protein localization GO:0070201 242 0.024
glycerolipid metabolic process GO:0046486 107 0.024
regulation of synaptic plasticity GO:0048167 3 0.024
epithelium development GO:0060429 227 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.024
negative regulation of catabolic process GO:0009895 104 0.024
circulatory system development GO:0072359 262 0.024
neural tube closure GO:0001843 3 0.024
ubiquitin dependent protein catabolic process GO:0006511 206 0.023
purine containing compound catabolic process GO:0072523 411 0.023
protein homooligomerization GO:0051260 100 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.023
embryonic epithelial tube formation GO:0001838 4 0.023
mitotic spindle checkpoint GO:0071174 18 0.023
cellular component disassembly GO:0022411 92 0.023
glycerophospholipid metabolic process GO:0006650 84 0.023
protein localization to nucleus GO:0034504 136 0.023
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.023
hematopoietic or lymphoid organ development GO:0048534 186 0.023
cellular response to cytokine stimulus GO:0071345 181 0.023
nuclear division GO:0000280 128 0.023
regulation of mitotic cell cycle GO:0007346 189 0.023
nitrogen compound transport GO:0071705 191 0.022
glycerolipid biosynthetic process GO:0045017 51 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
plasma membrane organization GO:0007009 115 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
vesicle mediated transport GO:0016192 371 0.022
regulation of cell adhesion GO:0030155 166 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
tissue homeostasis GO:0001894 63 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.022
chromatin organization GO:0006325 351 0.022
rho protein signal transduction GO:0007266 26 0.022
negative regulation of proteolysis GO:0045861 132 0.022
motor neuron axon guidance GO:0008045 2 0.022
telomere capping GO:0016233 5 0.022
response to oxygen containing compound GO:1901700 369 0.022
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.022
neuronal stem cell division GO:0036445 1 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.021
cellular component morphogenesis GO:0032989 314 0.021
positive regulation of cell death GO:0010942 263 0.021
anterior posterior axis specification GO:0009948 2 0.021
regulation of intracellular transport GO:0032386 195 0.021
phospholipid metabolic process GO:0006644 99 0.021
regulation of neuroblast proliferation GO:1902692 3 0.021
protein autophosphorylation GO:0046777 123 0.021
organophosphate biosynthetic process GO:0090407 163 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.021
mitotic spindle elongation GO:0000022 4 0.021
positive regulation of protein catabolic process GO:0045732 75 0.021
negative regulation of transferase activity GO:0051348 124 0.020
nucleocytoplasmic transport GO:0006913 176 0.020
cellular carbohydrate metabolic process GO:0044262 84 0.020
hindbrain development GO:0030902 3 0.020
oogenesis GO:0048477 2 0.020
cellular response to abiotic stimulus GO:0071214 117 0.020
amine metabolic process GO:0009308 44 0.020
negative regulation of telomerase activity GO:0051974 6 0.020
negative regulation of protein maturation GO:1903318 142 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.020
chemical homeostasis GO:0048878 306 0.020
cell fate commitment GO:0045165 27 0.020
associative learning GO:0008306 1 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
transmembrane transport GO:0055085 399 0.020
cell activation GO:0001775 213 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
protein auto adp ribosylation GO:0070213 4 0.020
phagosome lysosome fusion GO:0090385 4 0.020
negative regulation of peptidase activity GO:0010466 91 0.020
response to wounding GO:0009611 168 0.020
mesoderm development GO:0007498 14 0.019
multicellular organismal homeostasis GO:0048871 67 0.019
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.019
regulation of filopodium assembly GO:0051489 13 0.019
mrna metabolic process GO:0016071 175 0.019
positive regulation of cytoskeleton organization GO:0051495 83 0.019
somatic stem cell division GO:0048103 1 0.019
response to transforming growth factor beta GO:0071559 94 0.019
cellular lipid metabolic process GO:0044255 303 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
regulation of defense response GO:0031347 154 0.019
regulation of muscle cell differentiation GO:0051147 31 0.019
oxidation reduction process GO:0055114 396 0.019
brain development GO:0007420 97 0.019
memory GO:0007613 3 0.019
regulation of dna metabolic process GO:0051052 153 0.019
sensory perception of sound GO:0007605 37 0.019
spermatid differentiation GO:0048515 4 0.019
cell projection morphogenesis GO:0048858 129 0.018
golgi vesicle transport GO:0048193 80 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
positive regulation of homeostatic process GO:0032846 47 0.018
positive regulation of cell division GO:0051781 59 0.018
positive regulation of cell adhesion GO:0045785 84 0.018
covalent chromatin modification GO:0016569 254 0.018
negative regulation of cellular protein catabolic process GO:1903363 38 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.018
microtubule organizing center organization GO:0031023 62 0.018
nucleoside catabolic process GO:0009164 408 0.018
centrosome cycle GO:0007098 32 0.018
positive regulation of binding GO:0051099 45 0.018
female gamete generation GO:0007292 2 0.018
regulation of epithelial cell proliferation GO:0050678 113 0.018
regulation of protein serine threonine kinase activity GO:0071900 179 0.018
spindle elongation GO:0051231 4 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.017
regulation of protein localization GO:0032880 296 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
spindle checkpoint GO:0031577 26 0.017
negative regulation of epithelial cell proliferation GO:0050680 48 0.017
neurotransmitter secretion GO:0007269 4 0.017
cellular chemical homeostasis GO:0055082 180 0.017
cellular response to hypoxia GO:0071456 51 0.017
positive regulation of intracellular protein transport GO:0090316 76 0.017
protein polyubiquitination GO:0000209 110 0.017
telomere organization GO:0032200 33 0.017
response to abiotic stimulus GO:0009628 336 0.017
ion homeostasis GO:0050801 230 0.017
sequestering of calcium ion GO:0051208 17 0.017
response to biotic stimulus GO:0009607 276 0.017
macromolecular complex disassembly GO:0032984 60 0.017
positive regulation of cell projection organization GO:0031346 64 0.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.016
taxis GO:0042330 157 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.016
cation homeostasis GO:0055080 189 0.016
oocyte development GO:0048599 1 0.016
regulation of protein complex assembly GO:0043254 147 0.016
Fly
lipid metabolic process GO:0006629 381 0.016
regulation of angiogenesis GO:0045765 92 0.016
defense response to other organism GO:0098542 129 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
monovalent inorganic cation transport GO:0015672 128 0.016
regulation of gtpase activity GO:0043087 180 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.016
regulation of gtp catabolic process GO:0033124 180 0.016
regulation of cell motility GO:2000145 299 0.016
neurogenesis GO:0022008 169 0.016
regulation of mapk cascade GO:0043408 262 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
nerve development GO:0021675 4 0.016
primary neural tube formation GO:0014020 3 0.016
developmental programmed cell death GO:0010623 3 0.016
sequestering of metal ion GO:0051238 24 0.016
embryo development GO:0009790 123 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.016
positive regulation of axon extension GO:0045773 4 0.016
maintenance of location GO:0051235 112 0.016
positive regulation of synaptic transmission GO:0050806 4 0.015
response to other organism GO:0051707 261 0.015
regulation of vasculature development GO:1901342 97 0.015
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 15 0.015
negative regulation of dna binding GO:0043392 18 0.015
filopodium assembly GO:0046847 18 0.015
positive regulation of protein kinase activity GO:0045860 190 0.015
response to organic cyclic compound GO:0014070 204 0.015
regulation of mitotic sister chromatid separation GO:0010965 27 0.015
cellular metal ion homeostasis GO:0006875 146 0.015
single organismal cell cell adhesion GO:0016337 148 0.015
apoptotic signaling pathway GO:0097190 268 0.015
regulation of ion transport GO:0043269 189 0.015
cell type specific apoptotic process GO:0097285 125 0.015
regulation of neurotransmitter secretion GO:0046928 3 0.015
cellular cation homeostasis GO:0030003 163 0.015
regulation of map kinase activity GO:0043405 108 0.015
cellular amine metabolic process GO:0044106 41 0.015
activation of protein kinase activity GO:0032147 90 0.015
leukocyte differentiation GO:0002521 98 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
positive regulation of immune system process GO:0002684 283 0.015
regulation of chromosome segregation GO:0051983 44 0.015
negative regulation of protein catabolic process GO:0042177 59 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
head development GO:0060322 108 0.014
limbic system development GO:0021761 3 0.014
negative regulation of phosphorylation GO:0042326 174 0.014
negative regulation of protein transport GO:0051224 75 0.014
nuclear transport GO:0051169 179 0.014
regulation of protein transport GO:0051223 213 0.014
blastoderm segmentation GO:0007350 2 0.014
stress activated protein kinase signaling cascade GO:0031098 94 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
regulation of leukocyte activation GO:0002694 115 0.014
ion transmembrane transport GO:0034220 338 0.014
rab protein signal transduction GO:0032482 4 0.014
peripheral nervous system development GO:0007422 2 0.014
lymphocyte activation GO:0046649 133 0.014
convergent extension GO:0060026 1 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
hemopoiesis GO:0030097 180 0.014
embryonic placenta development GO:0001892 1 0.014
regeneration GO:0031099 4 0.014
lipoprotein metabolic process GO:0042157 42 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
regulation of immune response GO:0050776 201 0.014
response to cytokine GO:0034097 232 0.014
response to nitrogen compound GO:1901698 184 0.014
negative regulation of developmental growth GO:0048640 10 0.014
positive regulation of mitosis GO:0045840 25 0.014
dna biosynthetic process GO:0071897 40 0.014
phosphatidylinositol metabolic process GO:0046488 53 0.014
cerebellum development GO:0021549 2 0.014
immune effector process GO:0002252 159 0.014
negative regulation of immune system process GO:0002683 136 0.014
visual learning GO:0008542 1 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.013
cellular ion homeostasis GO:0006873 168 0.013
regulation of developmental growth GO:0048638 30 0.013
regulation of protein ubiquitination GO:0031396 95 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
sensory perception of mechanical stimulus GO:0050954 37 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
establishment of protein localization to membrane GO:0090150 121 0.013
response to axon injury GO:0048678 1 0.013
regulation of mitotic sister chromatid segregation GO:0033047 27 0.013
sensory organ development GO:0007423 52 0.013
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.013
mitotic sister chromatid separation GO:0051306 18 0.013
leukocyte activation GO:0045321 164 0.013
positive regulation of transferase activity GO:0051347 227 0.013
regulation of erk1 and erk2 cascade GO:0070372 99 0.013
response to decreased oxygen levels GO:0036293 96 0.013
tripartite regional subdivision GO:0007351 2 0.013
regulation of centrosome duplication GO:0010824 14 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
neural tube formation GO:0001841 3 0.013
epithelial tube branching involved in lung morphogenesis GO:0060441 4 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
response to fungus GO:0009620 4 0.013
lipid biosynthetic process GO:0008610 177 0.013
engulfment of apoptotic cell GO:0043652 2 0.013
cell cycle phase transition GO:0044770 173 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
membrane fusion GO:0061025 43 0.013
sensory perception of smell GO:0007608 2 0.013
negative regulation of kinase activity GO:0033673 106 0.013
centrosome duplication GO:0051298 28 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.013
response to hypoxia GO:0001666 96 0.013
regulation of short term neuronal synaptic plasticity GO:0048172 1 0.013

TNKS disease predictions

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 41 0.094
congenital nervous system abnormality DOID:2490 21 0.094
disease of cellular proliferation DOID:14566 174 0.064
cancer DOID:162 167 0.048
organ system cancer DOID:0050686 164 0.048
musculoskeletal system disease DOID:17 223 0.022
immune system disease DOID:2914 155 0.020
disease of metabolism DOID:0014667 295 0.020
retinal disease DOID:5679 118 0.018
sensory system disease DOID:0050155 203 0.018
eye and adnexa disease DOID:1492 150 0.018
nervous system disease DOID:863 431 0.018
eye disease DOID:5614 149 0.018
central nervous system disease DOID:331 186 0.017
disease of mental health DOID:150 70 0.015
muscular disease DOID:0080000 114 0.014
myopathy DOID:423 104 0.013
muscle tissue disease DOID:66 113 0.013
hypersensitivity reaction disease DOID:0060056 25 0.013