|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
1.000
|
|
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.992
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.927
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.857
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.838
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.808
|
|
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.793
|
Human |
|
|
macropinocytosis
|
GO:0044351 |
1 |
0.760
|
|
|
|
regulation of t cell chemotaxis
|
GO:0010819 |
7 |
0.715
|
|
|
|
positive regulation of protein localization to cell surface
|
GO:2000010 |
6 |
0.680
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.610
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.554
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.511
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.509
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.484
|
|
|
|
response to high density lipoprotein particle
|
GO:0055099 |
1 |
0.463
|
|
|
|
phagosome lysosome fusion
|
GO:0090385 |
4 |
0.447
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.445
|
Human |
|
|
caveola assembly
|
GO:0070836 |
4 |
0.435
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.412
|
|
|
|
protein lipid complex subunit organization
|
GO:0071825 |
24 |
0.397
|
Human |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.393
|
Human |
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
5 |
0.385
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.382
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
10 |
0.379
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.362
|
Human |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.361
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.359
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.352
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.348
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.348
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.342
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.336
|
|
|
|
positive regulation of epidermal growth factor activated receptor activity
|
GO:0045741 |
8 |
0.325
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.323
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.319
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.304
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.295
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.289
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.283
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.282
|
Human |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.282
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.282
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.271
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.259
|
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.256
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.256
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.255
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.243
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.241
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.238
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.235
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.233
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.227
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.225
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.224
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.221
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.221
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.220
|
|
|
|
memory
|
GO:0007613 |
3 |
0.220
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.220
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.219
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.218
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.216
|
Human |
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
12 |
0.207
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.205
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.203
|
Human |
|
|
lytic vacuole organization
|
GO:0080171 |
24 |
0.203
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.201
|
Human |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.200
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.199
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.196
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.193
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.190
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.189
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.186
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.185
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.179
|
Human |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.178
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.174
|
Human |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.174
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.173
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.173
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.173
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.172
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.172
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.171
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.171
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.170
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.167
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.163
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.162
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.162
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.159
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.159
|
|
|
|
phagolysosome assembly
|
GO:0001845 |
5 |
0.157
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.156
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.154
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
7 |
0.146
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.144
|
|
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.142
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.140
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.139
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.139
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.139
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.138
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.137
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.137
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.136
|
Human |
|
|
notch receptor processing
|
GO:0007220 |
2 |
0.135
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.134
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.132
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.132
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.132
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.131
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.131
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.131
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.130
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.129
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.129
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.129
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.128
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.126
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.125
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.124
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.124
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.118
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.115
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.113
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.111
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.109
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.109
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.109
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.106
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.106
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.105
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.105
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.104
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.104
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.102
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.101
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.101
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.100
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.098
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.097
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.095
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.094
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.094
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.094
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.093
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.093
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.091
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.091
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.091
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.091
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.090
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.090
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.088
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.088
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.088
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.088
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.087
|
|
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.087
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.087
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.085
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.085
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.085
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.084
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.084
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.084
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.084
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.083
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.083
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.083
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.083
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.081
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.080
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.079
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.079
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.078
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.078
|
|
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.077
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.076
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.076
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.076
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.076
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.076
|
Human |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.076
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.073
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.073
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.072
|
|
|
|
phagosome maturation
|
GO:0090382 |
9 |
0.072
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.072
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.072
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.071
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.070
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.070
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.069
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.069
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.069
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.069
|
|
|
|
endosome organization
|
GO:0007032 |
20 |
0.068
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.067
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.067
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.067
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.067
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.066
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.066
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.065
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.065
|
Human |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.064
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.064
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.063
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.063
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.063
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.062
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.062
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.062
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.062
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.062
|
|
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.062
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.062
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.061
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.061
|
|
|
|
protein lipid complex assembly
|
GO:0065005 |
12 |
0.061
|
Human |
|
|
heart development
|
GO:0007507 |
95 |
0.060
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.060
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.060
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.059
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.058
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.058
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.058
|
|
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.057
|
|
|
|
system process
|
GO:0003008 |
349 |
0.056
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.056
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.054
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.054
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.054
|
Human |
|
|
organelle fusion
|
GO:0048284 |
36 |
0.053
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.053
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.053
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.053
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.053
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.052
|
|
|
|
growth
|
GO:0040007 |
202 |
0.052
|
|
|
|
cleavage furrow formation
|
GO:0036089 |
5 |
0.052
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.052
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.052
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.051
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.051
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.051
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.050
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.050
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.049
|
Human |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.049
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.048
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.048
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.048
|
Human |
|
|
segmentation
|
GO:0035282 |
4 |
0.048
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.048
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.047
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.047
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.047
|
Human |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.047
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
15 |
0.047
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.047
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.046
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.046
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.046
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.046
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.046
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.045
|
|
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.045
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.045
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.045
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.045
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.045
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.044
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.044
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.044
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.043
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.043
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.043
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.043
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.042
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
16 |
0.042
|
|
|
|
head development
|
GO:0060322 |
108 |
0.042
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.041
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.041
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.040
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.040
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.040
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.040
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.040
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.040
|
Human |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.040
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.039
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.039
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.039
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.039
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.039
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.039
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.039
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.039
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.039
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.038
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.038
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.038
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.038
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.038
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.038
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.038
|
Human |
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.037
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.037
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.037
|
Human |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.037
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.037
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.037
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.037
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.036
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.036
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.036
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.036
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.036
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.036
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.036
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.035
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.035
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.035
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.035
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.035
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.035
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.035
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.035
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.034
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.034
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.034
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle
|
GO:0031659 |
8 |
0.034
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.034
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.034
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.034
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.034
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.034
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.034
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.034
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.034
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.034
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.034
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.034
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.034
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.034
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.034
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.034
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.033
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.033
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.033
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.033
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.033
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.033
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.033
|
|
|
|
azole transport
|
GO:0045117 |
4 |
0.032
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.032
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.032
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.031
|
Human |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.031
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.031
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.031
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.031
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.031
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.031
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.031
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.030
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.030
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.030
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.030
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.030
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.030
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.030
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.030
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.030
|
Human |
|
|
peptide transport
|
GO:0015833 |
74 |
0.030
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.030
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.030
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.030
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.030
|
|
|
|
lysosome organization
|
GO:0007040 |
24 |
0.030
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.029
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.029
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.029
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.029
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.029
|
|
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.029
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.029
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.029
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.028
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.028
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.028
|
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.028
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.028
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.028
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.028
|
|
|
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.028
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.028
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.028
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.027
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.027
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.027
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.027
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.027
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.027
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.026
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.026
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.026
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.026
|
|
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.026
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.026
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.026
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.026
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.026
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.025
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.025
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
27 |
0.025
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.025
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.025
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.025
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.025
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.025
|
|
|
|
mitochondrial fusion
|
GO:0008053 |
13 |
0.024
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.024
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.024
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.024
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.024
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.024
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.024
|
|
|
|
plasma membrane raft organization
|
GO:0044857 |
4 |
0.024
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.024
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.024
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.024
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.024
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.024
|
|
|
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.024
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.024
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.023
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.023
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.023
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.023
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.023
|
Human |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.023
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.023
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.023
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.023
|
|
|
|
positive regulation of homotypic cell cell adhesion
|
GO:0034112 |
4 |
0.022
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.022
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.022
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.022
|
Human |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.022
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.022
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.022
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.022
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.022
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.022
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.022
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.021
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.021
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.021
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.021
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.021
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.021
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.021
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.021
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.021
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.021
|
|
|
|
response to lipoprotein particle
|
GO:0055094 |
5 |
0.021
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.020
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.020
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
47 |
0.020
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.020
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.020
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.020
|
|