Homo sapiens

0 known processes

KLHL24

kelch-like 24 (Drosophila)

(Aliases: DRE1,KRIP6,FLJ25796)

KLHL24 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
hormone mediated signaling pathway GO:0009755 22 0.338
regulation of t helper 2 cell differentiation GO:0045628 1 0.324
cellular response to endogenous stimulus GO:0071495 336 0.256
immune system development GO:0002520 195 0.255
response to oxygen containing compound GO:1901700 369 0.244
response to hormone GO:0009725 175 0.236
response to organic cyclic compound GO:0014070 204 0.211
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.190
negative regulation of programmed cell death GO:0043069 321 0.177
single organism carbohydrate metabolic process GO:0044723 193 0.174
metal ion transport GO:0030001 272 0.170
response to steroid hormone GO:0048545 80 0.155
cellular response to hormone stimulus GO:0032870 125 0.155
lipid metabolic process GO:0006629 381 0.144
mitochondrial rna metabolic process GO:0000959 15 0.130
cellular response to lipid GO:0071396 127 0.127
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.122
cellular ketone metabolic process GO:0042180 80 0.119
protein dna complex assembly GO:0065004 64 0.115
protein modification by small protein conjugation GO:0032446 342 0.113
negative regulation of cell cycle GO:0045786 193 0.105
regulation of carbohydrate metabolic process GO:0006109 54 0.103
response to lipid GO:0033993 206 0.102
t helper cell differentiation GO:0042093 4 0.100
histone demethylation GO:0016577 15 0.100
monosaccharide metabolic process GO:0005996 74 0.097
regulation of cell cycle GO:0051726 393 0.093
positive regulation of interleukin 13 production GO:0032736 4 0.092
cellular response to organic cyclic compound GO:0071407 127 0.091
cellular response to glucocorticoid stimulus GO:0071385 4 0.089
positive regulation of transport GO:0051050 336 0.088
cellular response to steroid hormone stimulus GO:0071383 37 0.086
protein ubiquitination GO:0016567 314 0.083
mitotic cell cycle phase transition GO:0044772 162 0.083
steroid hormone mediated signaling pathway GO:0043401 12 0.083
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.082
monovalent inorganic cation transport GO:0015672 128 0.081
positive regulation of immune response GO:0050778 159 0.081
regulation of mitotic cell cycle GO:0007346 189 0.076
transcription from mitochondrial promoter GO:0006390 7 0.074
response to estrogen GO:0043627 47 0.073
cytokine production GO:0001816 247 0.072
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.071
positive regulation of cellular amine metabolic process GO:0033240 7 0.069
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.065
mrna catabolic process GO:0006402 56 0.065
carboxylic acid transport GO:0046942 63 0.065
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.064
immune response activating signal transduction GO:0002757 90 0.063
organic acid transport GO:0015849 65 0.063
amine metabolic process GO:0009308 44 0.061
cellular response to dna damage stimulus GO:0006974 379 0.060
cellular response to topologically incorrect protein GO:0035967 19 0.059
negative regulation of mitotic cell cycle GO:0045930 102 0.058
mitotic cell cycle GO:0000278 326 0.055
locomotory behavior GO:0007626 1 0.055
anion transport GO:0006820 161 0.054
negative regulation of catalytic activity GO:0043086 335 0.053
cellular macromolecular complex assembly GO:0034622 324 0.052
response to corticosteroid GO:0031960 15 0.052
ribonucleoside triphosphate catabolic process GO:0009203 391 0.049
protein dealkylation GO:0008214 17 0.049
positive regulation of interleukin 4 production GO:0032753 3 0.049
chromatin modification GO:0016568 298 0.048
regulation of cellular component biogenesis GO:0044087 281 0.048
regulation of leukocyte activation GO:0002694 115 0.045
energy homeostasis GO:0097009 3 0.044
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.044
macromolecule methylation GO:0043414 97 0.044
t helper 2 cell differentiation GO:0045064 1 0.044
negative regulation of cell death GO:0060548 345 0.042
negative regulation of synaptic transmission GO:0050805 2 0.041
regulation of cellular ketone metabolic process GO:0010565 50 0.040
cellular response to oxygen containing compound GO:1901701 276 0.039
chromatin organization GO:0006325 351 0.038
myeloid cell differentiation GO:0030099 117 0.038
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.038
lipid homeostasis GO:0055088 39 0.037
cellular amine metabolic process GO:0044106 41 0.037
demethylation GO:0070988 37 0.036
negative regulation of immune system process GO:0002683 136 0.036
protein catabolic process GO:0030163 325 0.036
positive regulation of cell activation GO:0050867 81 0.036
oxidation reduction process GO:0055114 396 0.036
immune response regulating signaling pathway GO:0002764 97 0.035
nucleobase containing compound transport GO:0015931 51 0.035
leukocyte activation GO:0045321 164 0.035
rhythmic behavior GO:0007622 2 0.034
organophosphate ester transport GO:0015748 32 0.034
hexose metabolic process GO:0019318 55 0.034
circulatory system development GO:0072359 262 0.033
dna templated transcription initiation GO:0006352 35 0.032
negative regulation of multicellular organismal process GO:0051241 317 0.032
positive regulation of catabolic process GO:0009896 310 0.032
regulation of immune response GO:0050776 201 0.031
response to topologically incorrect protein GO:0035966 29 0.031
protein dna complex subunit organization GO:0071824 80 0.030
cation transport GO:0006812 331 0.030
immune response GO:0006955 307 0.030
divalent metal ion transport GO:0070838 152 0.030
behavior GO:0007610 112 0.030
regulation of protein localization GO:0032880 296 0.030
carbohydrate metabolic process GO:0005975 207 0.030
mitochondrial transport GO:0006839 60 0.029
negative regulation of cell differentiation GO:0045596 171 0.029
positive regulation of protein transport GO:0051222 135 0.029
mitotic cell cycle process GO:1903047 286 0.028
genetic imprinting GO:0071514 1 0.028
positive regulation of ion transport GO:0043270 87 0.028
somitogenesis GO:0001756 2 0.028
neuromuscular junction development GO:0007528 3 0.027
regulation of protein transport GO:0051223 213 0.027
positive regulation of protein catabolic process GO:0045732 75 0.027
immune effector process GO:0002252 159 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
regulation of t helper cell differentiation GO:0045622 3 0.027
oogenesis GO:0048477 2 0.027
regulation of purine nucleotide catabolic process GO:0033121 205 0.027
regulation of cell activation GO:0050865 125 0.027
positive regulation of t cell activation GO:0050870 54 0.026
pattern recognition receptor signaling pathway GO:0002221 48 0.026
dna repair GO:0006281 198 0.025
vesicle mediated transport GO:0016192 371 0.025
hematopoietic or lymphoid organ development GO:0048534 186 0.025
leukocyte differentiation GO:0002521 98 0.025
hemopoiesis GO:0030097 180 0.025
positive regulation of intracellular transport GO:0032388 104 0.025
negative regulation of developmental process GO:0051093 247 0.025
purine nucleoside triphosphate metabolic process GO:0009144 412 0.025
regulation of protein catabolic process GO:0042176 155 0.024
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 3 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.024
positive regulation of cytokine mediated signaling pathway GO:0001961 12 0.024
negative regulation of protein modification process GO:0031400 200 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.024
extrinsic apoptotic signaling pathway GO:0097191 119 0.024
regulation of cytokine production GO:0001817 232 0.023
cardiovascular system development GO:0072358 262 0.023
modification dependent macromolecule catabolic process GO:0043632 212 0.023
cellular response to biotic stimulus GO:0071216 71 0.023
positive regulation of cell proliferation GO:0008284 301 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
negative regulation of cell cycle process GO:0010948 121 0.023
myeloid leukocyte differentiation GO:0002573 60 0.023
mrna metabolic process GO:0016071 175 0.022
segmentation GO:0035282 4 0.022
protein alkylation GO:0008213 74 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
regulation of interleukin 5 production GO:0032674 6 0.022
er nucleus signaling pathway GO:0006984 23 0.022
regulation of t cell activation GO:0050863 77 0.022
regulation of cellular response to stress GO:0080135 244 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
response to unfolded protein GO:0006986 24 0.021
response to acid chemical GO:0001101 66 0.021
regulation of apoptotic signaling pathway GO:2001233 175 0.021
system process GO:0003008 349 0.021
pyruvate transport GO:0006848 1 0.021
regulation of potassium ion transport GO:0043266 24 0.021
cellular macromolecule catabolic process GO:0044265 380 0.020
regulation of interferon gamma production GO:0032649 36 0.020
negative regulation of protein metabolic process GO:0051248 391 0.020
positive regulation of immune system process GO:0002684 283 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
activation of innate immune response GO:0002218 55 0.020
multicellular organismal aging GO:0010259 3 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.020
regulation of tumor necrosis factor production GO:0032680 43 0.020
activation of immune response GO:0002253 114 0.020
cell morphogenesis GO:0000902 296 0.019
response to sterol GO:0036314 14 0.019
negative regulation of apoptotic process GO:0043066 316 0.019
response to alcohol GO:0097305 64 0.019
protein demethylation GO:0006482 17 0.019
cellular carbohydrate metabolic process GO:0044262 84 0.019
positive regulation of cytokine production GO:0001819 167 0.019
rho protein signal transduction GO:0007266 26 0.019
regulation of cell morphogenesis GO:0022604 153 0.019
nuclear transcribed mrna catabolic process GO:0000956 48 0.019
mitochondrion distribution GO:0048311 3 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.018
gtp metabolic process GO:0046039 239 0.018
positive regulation of developmental process GO:0051094 314 0.018
regulation of small gtpase mediated signal transduction GO:0051056 156 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
cellular amino acid metabolic process GO:0006520 116 0.018
positive regulation of protein complex assembly GO:0031334 86 0.018
regulation of intracellular transport GO:0032386 195 0.018
intracellular receptor signaling pathway GO:0030522 104 0.018
response to estradiol GO:0032355 23 0.017
histone lysine methylation GO:0034968 50 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
negative regulation of hydrolase activity GO:0051346 182 0.017
generation of precursor metabolites and energy GO:0006091 68 0.017
purine ribonucleotide catabolic process GO:0009154 404 0.017
cellular protein catabolic process GO:0044257 261 0.017
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 2 0.017
divalent inorganic cation transport GO:0072511 158 0.017
response to other organism GO:0051707 261 0.017
monocarboxylic acid transport GO:0015718 32 0.016
response to cytokine GO:0034097 232 0.016
potassium ion transport GO:0006813 62 0.016
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0017055 2 0.016
protein localization to nucleus GO:0034504 136 0.016
tumor necrosis factor production GO:0032640 43 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
cellular response to corticosteroid stimulus GO:0071384 5 0.016
regulation of immune effector process GO:0002697 91 0.016
regulation of metal ion transport GO:0010959 120 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
regulation of cell cycle process GO:0010564 266 0.016
organophosphate biosynthetic process GO:0090407 163 0.016
positive regulation of cellular component biogenesis GO:0044089 158 0.016
organic anion transport GO:0015711 103 0.016
spermatid development GO:0007286 4 0.016
histone lysine demethylation GO:0070076 14 0.015
cell activation GO:0001775 213 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
regulation of myeloid cell differentiation GO:0045637 81 0.015
determination of adult lifespan GO:0008340 2 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
regulation of inflammatory response GO:0050727 46 0.015
neurotransmitter secretion GO:0007269 4 0.015
regulation of protein complex assembly GO:0043254 147 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
protein polyubiquitination GO:0000209 110 0.015
energy derivation by oxidation of organic compounds GO:0015980 43 0.015
meiosis i GO:0007127 4 0.015
histone modification GO:0016570 251 0.015
mapk cascade GO:0000165 288 0.015
nucleoside triphosphate metabolic process GO:0009141 422 0.015
nucleotide catabolic process GO:0009166 408 0.015
heart development GO:0007507 95 0.015
rab protein signal transduction GO:0032482 4 0.015
cell cycle checkpoint GO:0000075 117 0.014
response to abiotic stimulus GO:0009628 336 0.014
regulation of transferase activity GO:0051338 355 0.014
regulation of response to external stimulus GO:0032101 222 0.014
cellular response to retinoic acid GO:0071300 19 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
digestive system development GO:0055123 75 0.014
organelle assembly GO:0070925 176 0.014
positive regulation of innate immune response GO:0045089 79 0.014
cell projection assembly GO:0030031 126 0.014
regulation of cell differentiation GO:0045595 393 0.014
positive regulation of type 2 immune response GO:0002830 2 0.014
cell development GO:0048468 328 0.014
positive regulation of t helper cell differentiation GO:0045624 2 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
response to biotic stimulus GO:0009607 276 0.014
positive regulation of potassium ion transport GO:0043268 15 0.014
digestive tract development GO:0048565 75 0.014
regulation of alpha beta t cell activation GO:0046634 13 0.014
peptidyl lysine modification GO:0018205 144 0.014
toll like receptor signaling pathway GO:0002224 25 0.014
mitochondrion organization GO:0007005 156 0.014
regulation of cytoskeleton organization GO:0051493 177 0.013
ras protein signal transduction GO:0007265 73 0.013
regulation of muscle tissue development GO:1901861 26 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
regulation of ion transport GO:0043269 189 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
multicellular organismal homeostasis GO:0048871 67 0.013
regulation of lipid metabolic process GO:0019216 96 0.013
regulation of innate immune response GO:0045088 97 0.013
lipid biosynthetic process GO:0008610 177 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
peptidyl lysine methylation GO:0018022 37 0.013
post embryonic development GO:0009791 2 0.013
circadian behavior GO:0048512 2 0.013
regulation of skeletal muscle tissue development GO:0048641 15 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
defense response GO:0006952 315 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
cellular response to extracellular stimulus GO:0031668 72 0.013
positive regulation of cell cycle GO:0045787 140 0.013
glycoprotein biosynthetic process GO:0009101 91 0.013
apoptotic signaling pathway GO:0097190 268 0.012
cofactor transport GO:0051181 11 0.012
muscle organ development GO:0007517 56 0.012
dna methylation or demethylation GO:0044728 19 0.012
dna integration GO:0015074 3 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
negative regulation of dephosphorylation GO:0035305 63 0.012
negative regulation of cell cycle phase transition GO:1901988 89 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
purine containing compound catabolic process GO:0072523 411 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
positive regulation of response to cytokine stimulus GO:0060760 13 0.012
rna 3 end processing GO:0031123 35 0.012
cytokine mediated signaling pathway GO:0019221 109 0.012
t cell activation GO:0042110 99 0.012
negative regulation of tumor necrosis factor production GO:0032720 20 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
response to bacterium GO:0009617 144 0.012
positive regulation of binding GO:0051099 45 0.012
cellular response to nutrient levels GO:0031669 69 0.012
retinoic acid receptor signaling pathway GO:0048384 13 0.012
endosomal transport GO:0016197 129 0.012
positive regulation of cd4 positive alpha beta t cell activation GO:2000516 3 0.012
regulation of gtpase activity GO:0043087 180 0.012
cilium assembly GO:0042384 63 0.012
female gamete generation GO:0007292 2 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
hindbrain development GO:0030902 3 0.012
cellular component morphogenesis GO:0032989 314 0.011
male sex differentiation GO:0046661 25 0.011
regulation of canonical wnt signaling pathway GO:0060828 88 0.011
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.011
cytoplasmic transport GO:0016482 379 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.011
glucose metabolic process GO:0006006 45 0.011
regulation of dna templated transcription initiation GO:2000142 9 0.011
covalent chromatin modification GO:0016569 254 0.011
dephosphorylation GO:0016311 209 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.011
mitotic cell cycle checkpoint GO:0007093 68 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
dna damage checkpoint GO:0000077 68 0.011
lymphocyte activation GO:0046649 133 0.011
chemotaxis GO:0006935 157 0.011
forebrain neuron development GO:0021884 2 0.011
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 3 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
metencephalon development GO:0022037 2 0.011
methylation GO:0032259 106 0.011
cell cell signaling GO:0007267 155 0.011
glycerophospholipid biosynthetic process GO:0046474 40 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
male gonad development GO:0008584 23 0.011
positive regulation of hydrolase activity GO:0051345 331 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
histone methylation GO:0016571 60 0.011
regulation of lymphocyte proliferation GO:0050670 64 0.011
innate immune response activating signal transduction GO:0002758 48 0.011
rna processing GO:0006396 255 0.011
response to oxygen levels GO:0070482 100 0.011
purine nucleoside triphosphate catabolic process GO:0009146 392 0.011
carbohydrate derivative transport GO:1901264 20 0.011
positive regulation of leukocyte differentiation GO:1902107 37 0.010
response to endoplasmic reticulum stress GO:0034976 49 0.010
regulation of binding GO:0051098 111 0.010
positive regulation of defense response GO:0031349 87 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
regulation of response to wounding GO:1903034 101 0.010
reproductive process GO:0022414 106 0.010
cellular response to unfolded protein GO:0034620 16 0.010
epithelium development GO:0060429 227 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
positive regulation of cytoskeleton organization GO:0051495 83 0.010
actin filament organization GO:0007015 128 0.010
positive regulation of leukocyte activation GO:0002696 80 0.010
signal transduction by p53 class mediator GO:0072331 72 0.010

KLHL24 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.056
disease of cellular proliferation DOID:14566 174 0.056
organ system cancer DOID:0050686 164 0.056
disease of metabolism DOID:0014667 295 0.021
breast cancer DOID:1612 21 0.016
thoracic cancer DOID:5093 21 0.016
sensory system disease DOID:0050155 203 0.016
nervous system disease DOID:863 431 0.016
gastrointestinal system cancer DOID:3119 52 0.013