Homo sapiens

37 known processes

POLB

polymerase (DNA directed), beta

(Aliases: MGC125976)

POLB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.084
nucleoside catabolic process GO:0009164 408 0.064
dna repair GO:0006281 198 0.061
cellular macromolecule catabolic process GO:0044265 380 0.059
regulation of cell cycle GO:0051726 393 0.058
cytoplasmic transport GO:0016482 379 0.048
purine nucleoside catabolic process GO:0006152 398 0.047
oogenesis GO:0048477 2 0.044
glycosyl compound catabolic process GO:1901658 413 0.042
positive regulation of hydrolase activity GO:0051345 331 0.042
ribonucleotide catabolic process GO:0009261 405 0.041
positive regulation of catabolic process GO:0009896 310 0.041
ribonucleoside triphosphate catabolic process GO:0009203 391 0.041
small gtpase mediated signal transduction GO:0007264 78 0.040
nucleotide catabolic process GO:0009166 408 0.040
purine ribonucleotide catabolic process GO:0009154 404 0.040
organ formation GO:0048645 3 0.040
organophosphate catabolic process GO:0046434 430 0.038
ras protein signal transduction GO:0007265 73 0.037
purine nucleoside triphosphate catabolic process GO:0009146 392 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
cellular amino acid metabolic process GO:0006520 116 0.036
purine containing compound catabolic process GO:0072523 411 0.036
regulation of cell differentiation GO:0045595 393 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
nucleoside phosphate catabolic process GO:1901292 412 0.035
mitotic cell cycle GO:0000278 326 0.035
response to abiotic stimulus GO:0009628 336 0.034
Rat
purine ribonucleoside metabolic process GO:0046128 437 0.034
ribonucleoside catabolic process GO:0042454 406 0.034
modification dependent protein catabolic process GO:0019941 209 0.033
single organism cellular localization GO:1902580 332 0.032
ribonucleoside triphosphate metabolic process GO:0009199 412 0.032
cellular component morphogenesis GO:0032989 314 0.031
membrane organization GO:0061024 292 0.031
regeneration GO:0031099 4 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.030
protein catabolic process GO:0030163 325 0.030
female gamete generation GO:0007292 2 0.030
establishment of protein localization to membrane GO:0090150 121 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
rho protein signal transduction GO:0007266 26 0.029
cellular response to endogenous stimulus GO:0071495 336 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
cellular response to dna damage stimulus GO:0006974 379 0.028
system process GO:0003008 349 0.028
gtp metabolic process GO:0046039 239 0.028
nervous system development GO:0007399 293 0.028
cell fate commitment involved in pattern specification GO:0060581 1 0.028
cell morphogenesis GO:0000902 296 0.028
negative regulation of programmed cell death GO:0043069 321 0.027
microtubule based process GO:0007017 210 0.027
cell fate determination GO:0001709 3 0.027
single organism membrane organization GO:0044802 268 0.027
regulation of protein localization GO:0032880 296 0.027
positive regulation of cellular component organization GO:0051130 376 0.027
mitotic cell cycle process GO:1903047 286 0.027
purine ribonucleoside catabolic process GO:0046130 398 0.027
microtubule cytoskeleton organization GO:0000226 176 0.026
actin filament based process GO:0030029 224 0.026
negative regulation of multicellular organismal process GO:0051241 317 0.026
cdc42 protein signal transduction GO:0032488 4 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
cellular protein catabolic process GO:0044257 261 0.025
proteasomal protein catabolic process GO:0010498 176 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
cell projection organization GO:0030030 252 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
regulation of purine nucleotide catabolic process GO:0033121 205 0.024
cellular ketone metabolic process GO:0042180 80 0.023
determination of adult lifespan GO:0008340 2 0.023
tissue regeneration GO:0042246 3 0.023
regulation of gtp catabolic process GO:0033124 180 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
regulation of gtpase activity GO:0043087 180 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
double strand break repair GO:0006302 101 0.022
modification dependent macromolecule catabolic process GO:0043632 212 0.022
dna replication GO:0006260 116 0.022
response to oxygen containing compound GO:1901700 369 0.022
Rat
ubiquitin dependent protein catabolic process GO:0006511 206 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
cellular amine metabolic process GO:0044106 41 0.022
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
protein acetylation GO:0006473 116 0.022
positive regulation of transport GO:0051050 336 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
protein maturation GO:0051604 233 0.022
neuromuscular junction development GO:0007528 3 0.022
gtp catabolic process GO:0006184 237 0.021
apoptotic signaling pathway GO:0097190 268 0.021
Mouse
locomotory behavior GO:0007626 1 0.021
endomembrane system organization GO:0010256 196 0.021
mitotic cell cycle phase transition GO:0044772 162 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
regulation of ras protein signal transduction GO:0046578 155 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.021
protein localization to organelle GO:0033365 280 0.021
regulation of proteolysis GO:0030162 293 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.021
signal transduction by phosphorylation GO:0023014 297 0.021
regulation of cell cycle process GO:0010564 266 0.020
response to radiation GO:0009314 151 0.020
Rat
protein modification by small protein conjugation GO:0032446 342 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
multicellular organismal aging GO:0010259 3 0.020
negative regulation of cell cycle GO:0045786 193 0.020
positive regulation of cell death GO:0010942 263 0.020
protein localization to membrane GO:0072657 160 0.020
negative regulation of cell fate commitment GO:0010454 3 0.020
positive regulation of gtpase activity GO:0043547 166 0.020
regulation of growth GO:0040008 165 0.019
vesicle mediated transport GO:0016192 371 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.019
negative regulation of cell death GO:0060548 345 0.019
intracellular protein transport GO:0006886 270 0.019
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
activation of cdc42 gtpase activity GO:0032864 2 0.019
adult locomotory behavior GO:0008344 1 0.019
spermatid differentiation GO:0048515 4 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
memory GO:0007613 3 0.018
metencephalon development GO:0022037 2 0.018
nitrogen compound transport GO:0071705 191 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
regulation of protein kinase activity GO:0045859 289 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
hindbrain development GO:0030902 3 0.018
positive regulation of developmental process GO:0051094 314 0.018
negative regulation of cell proliferation GO:0008285 228 0.018
segmentation GO:0035282 4 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
tripartite regional subdivision GO:0007351 2 0.018
multicellular organismal response to stress GO:0033555 1 0.017
carbohydrate metabolic process GO:0005975 207 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
mating GO:0007618 1 0.017
lipid metabolic process GO:0006629 381 0.017
transmembrane transport GO:0055085 399 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
blastoderm segmentation GO:0007350 2 0.017
positive regulation of ras gtpase activity GO:0032320 117 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
spermatid development GO:0007286 4 0.017
viral life cycle GO:0019058 132 0.017
anterior posterior axis specification GO:0009948 2 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
chemical homeostasis GO:0048878 306 0.016
negative regulation of cell differentiation GO:0045596 171 0.016
negative regulation of developmental process GO:0051093 247 0.016
regulation of kinase activity GO:0043549 314 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
actin cytoskeleton organization GO:0030036 207 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
regulation of cell morphogenesis GO:0022604 153 0.016
amine metabolic process GO:0009308 44 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
response to organic cyclic compound GO:0014070 204 0.016
positive regulation of gtp catabolic process GO:0033126 166 0.015
stem cell division GO:0017145 2 0.015
nuclear transport GO:0051169 179 0.015
regulation of ras gtpase activity GO:0032318 128 0.015
rhythmic behavior GO:0007622 2 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
regulation of transferase activity GO:0051338 355 0.015
growth GO:0040007 202 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
protein targeting GO:0006605 187 0.015
dephosphorylation GO:0016311 209 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
biological adhesion GO:0022610 331 0.015
positive regulation of transferase activity GO:0051347 227 0.015
response to oxidative stress GO:0006979 121 0.015
neurotransmitter secretion GO:0007269 4 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.014
regulation of intracellular transport GO:0032386 195 0.014
cell cycle phase transition GO:0044770 173 0.014
positive regulation of apoptotic process GO:0043065 246 0.014
neurogenesis GO:0022008 169 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.014
cell adhesion GO:0007155 325 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
protein acylation GO:0043543 138 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
defense response GO:0006952 315 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
immune response GO:0006955 307 0.014
histone modification GO:0016570 251 0.014
cellular homeostasis GO:0019725 196 0.014
regulation of cellular response to stress GO:0080135 244 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
compound eye development GO:0048749 1 0.014
regulation of multi organism process GO:0043900 157 0.014
positive regulation of cellular amine metabolic process GO:0033240 7 0.014
interspecies interaction between organisms GO:0044419 156 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
regulation of cytokine production GO:0001817 232 0.014
nerve development GO:0021675 4 0.014
histone h4 k5 acetylation GO:0043981 15 0.014
negative regulation of protein processing GO:0010955 142 0.014
peripheral nervous system development GO:0007422 2 0.014
mitotic spindle elongation GO:0000022 4 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
negative regulation of proteolysis GO:0045861 132 0.013
neurological system process GO:0050877 163 0.013
cell projection morphogenesis GO:0048858 129 0.013
cell part morphogenesis GO:0032990 137 0.013
regulation of protein processing GO:0070613 150 0.013
nuclear migration GO:0007097 1 0.013
metal ion transport GO:0030001 272 0.013
protein processing GO:0016485 226 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
histone h3 acetylation GO:0043966 45 0.013
positive regulation of kinase activity GO:0033674 204 0.013
protein ubiquitination GO:0016567 314 0.013
regulation of protein catabolic process GO:0042176 155 0.013
circadian behavior GO:0048512 2 0.013
neuron projection development GO:0031175 106 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
covalent chromatin modification GO:0016569 254 0.013
regulation of protein transport GO:0051223 213 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
negative regulation of protein maturation GO:1903318 142 0.013
mapk cascade GO:0000165 288 0.013
ion homeostasis GO:0050801 230 0.013
regulation of secretion GO:0051046 194 0.013
actin mediated cell contraction GO:0070252 12 0.013
reproductive process GO:0022414 106 0.013
rna processing GO:0006396 255 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
cellular lipid metabolic process GO:0044255 303 0.013
regulation of protein maturation GO:1903317 150 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
associative learning GO:0008306 1 0.012
phototransduction GO:0007602 3 0.012
oocyte differentiation GO:0009994 2 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
response to hormone GO:0009725 175 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
positive regulation of immune system process GO:0002684 283 0.012
sex determination GO:0007530 3 0.012
cell division GO:0051301 168 0.012
cerebellum development GO:0021549 2 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
neuron development GO:0048666 113 0.012
cell development GO:0048468 328 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
small molecule biosynthetic process GO:0044283 157 0.012
chemotaxis GO:0006935 157 0.012
cation transport GO:0006812 331 0.012
atp metabolic process GO:0046034 176 0.012
spindle elongation GO:0051231 4 0.012
generation of neurons GO:0048699 152 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
cation transmembrane transport GO:0098655 238 0.012
positive regulation of protein transport GO:0051222 135 0.012
epithelial cell differentiation GO:0030855 141 0.012
regulation of dna metabolic process GO:0051052 153 0.012
muscle system process GO:0003012 81 0.012
response to lipid GO:0033993 206 0.012
cytokine production GO:0001816 247 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
divalent metal ion transport GO:0070838 152 0.012
limbic system development GO:0021761 3 0.012
cellular cation homeostasis GO:0030003 163 0.012
response to growth factor GO:0070848 205 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.012
secretion by cell GO:0032940 226 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
mitotic nuclear division GO:0007067 119 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
wound healing GO:0042060 115 0.011
response to axon injury GO:0048678 1 0.011
maintenance of location GO:0051235 112 0.011
oocyte development GO:0048599 1 0.011
glycoprotein metabolic process GO:0009100 110 0.011
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
ion transmembrane transport GO:0034220 338 0.011
response to cytokine GO:0034097 232 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
positive regulation of cell cycle GO:0045787 140 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
sequestering of metal ion GO:0051238 24 0.011
response to fungus GO:0009620 4 0.011
meiosis i GO:0007127 4 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
specification of organ identity GO:0010092 3 0.011
regulation of protein serine threonine kinase activity GO:0071900 179 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
cation homeostasis GO:0055080 189 0.011
sequestering of calcium ion GO:0051208 17 0.011
chromatin modification GO:0016568 298 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of mapk cascade GO:0043408 262 0.011
endocytosis GO:0006897 159 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
regulation of response to external stimulus GO:0032101 222 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
nuclear export GO:0051168 69 0.011
signal transduction by p53 class mediator GO:0072331 72 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
response to nitrogen compound GO:1901698 184 0.011
cranial nerve development GO:0021545 4 0.010
lipid biosynthetic process GO:0008610 177 0.010
dendritic spine morphogenesis GO:0060997 3 0.010
divalent inorganic cation transport GO:0072511 158 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
response to biotic stimulus GO:0009607 276 0.010
multi organism cellular process GO:0044764 156 0.010
metal ion homeostasis GO:0055065 169 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
epithelium development GO:0060429 227 0.010
regulation of actin filament based process GO:0032970 141 0.010
innate immune response GO:0045087 178 0.010
monocarboxylic acid biosynthetic process GO:0072330 67 0.010
actin filament based movement GO:0030048 17 0.010
cellular response to lipid GO:0071396 127 0.010
autophagy GO:0006914 88 0.010
visual behavior GO:0007632 2 0.010
sensory perception of pain GO:0019233 4 0.010
histone h4 acetylation GO:0043967 47 0.010
histone h4 k8 acetylation GO:0043982 15 0.010
regulation of immune response GO:0050776 201 0.010
calcium ion transport GO:0006816 147 0.010
inner ear morphogenesis GO:0042472 4 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
cell cell signaling GO:0007267 155 0.010
protein import GO:0017038 130 0.010

POLB disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.030
inherited metabolic disorder DOID:655 242 0.027
sensory system disease DOID:0050155 203 0.022
eye and adnexa disease DOID:1492 150 0.022
nervous system disease DOID:863 431 0.022
eye disease DOID:5614 149 0.022
central nervous system disease DOID:331 186 0.019
retinal disease DOID:5679 118 0.016
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
musculoskeletal system disease DOID:17 223 0.015
immune system disease DOID:2914 155 0.014
retinal degeneration DOID:8466 89 0.013
neurodegenerative disease DOID:1289 102 0.012
organ system cancer DOID:0050686 164 0.012
brain disease DOID:936 73 0.011