Homo sapiens

88 known processes

TRIM22

tripartite motif containing 22

(Aliases: RNF94,STAF50,GPSTAF50)

TRIM22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 247 0.968
Human
immune effector process GO:0002252 159 0.951
Human
defense response to virus GO:0051607 71 0.951
Human
response to other organism GO:0051707 261 0.929
Human
response to biotic stimulus GO:0009607 276 0.898
Human
response to virus GO:0009615 126 0.811
Human
immune response GO:0006955 307 0.739
Human
response to external biotic stimulus GO:0043207 261 0.737
Human
regulation of defense response GO:0031347 154 0.710
Human
positive regulation of defense response GO:0031349 87 0.705
Human
regulation of cytokine production GO:0001817 232 0.665
Human
activation of innate immune response GO:0002218 55 0.646
Human
positive regulation of immune system process GO:0002684 283 0.640
Human
defense response to other organism GO:0098542 129 0.630
Human
regulation of multi organism process GO:0043900 157 0.591
Human
viral process GO:0016032 146 0.540
Human
positive regulation of interleukin 1 beta secretion GO:0050718 11 0.507
multi organism cellular process GO:0044764 156 0.482
Human
negative regulation of protein maturation GO:1903318 142 0.478
Human
defense response GO:0006952 315 0.467
Human
viral life cycle GO:0019058 132 0.450
Human
immune response activating signal transduction GO:0002757 90 0.383
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.371
Human
response to cytokine GO:0034097 232 0.367
pattern recognition receptor signaling pathway GO:0002221 48 0.339
Human
protein maturation GO:0051604 233 0.337
Human
regulation of protein secretion GO:0050708 86 0.326
Human
innate immune response GO:0045087 178 0.324
Human
positive regulation of immune response GO:0050778 159 0.284
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.282
Human
interspecies interaction between organisms GO:0044419 156 0.279
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.265
positive regulation of developmental process GO:0051094 314 0.262
positive regulation of cell death GO:0010942 263 0.255
Human
positive regulation of cytokine production GO:0001819 167 0.242
Human
response to molecule of bacterial origin GO:0002237 82 0.232
Human
regulation of defense response to virus GO:0050688 33 0.214
Human
regulation of innate immune response GO:0045088 97 0.199
Human
activation of immune response GO:0002253 114 0.190
Human
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.185
regulation of immune response GO:0050776 201 0.181
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.178
negative regulation of catalytic activity GO:0043086 335 0.162
Human
regulation of response to external stimulus GO:0032101 222 0.152
Human
intracellular receptor signaling pathway GO:0030522 104 0.147
Human
regulation of interleukin 1 beta secretion GO:0050706 12 0.143
regulation of proteolysis GO:0030162 293 0.139
Human
protein processing GO:0016485 226 0.137
Human
negative regulation of viral genome replication GO:0045071 35 0.132
regulation of apoptotic signaling pathway GO:2001233 175 0.130
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.130
Human
response to bacterium GO:0009617 144 0.121
Human
positive regulation of innate immune response GO:0045089 79 0.121
Human
regulation of protein processing GO:0070613 150 0.119
Human
negative regulation of immune system process GO:0002683 136 0.116
Human
regulation of cytokine secretion GO:0050707 57 0.115
Human
regulation of response to biotic stimulus GO:0002831 55 0.112
Human
regulation of leukocyte activation GO:0002694 115 0.110
immune response regulating signaling pathway GO:0002764 97 0.110
Human
positive regulation of apoptotic process GO:0043065 246 0.106
Human
regulation of establishment of protein localization GO:0070201 242 0.102
Human
positive regulation of peptidase activity GO:0010952 88 0.100
hemopoiesis GO:0030097 180 0.100
cell activation GO:0001775 213 0.100
hematopoietic or lymphoid organ development GO:0048534 186 0.099
leukocyte activation GO:0045321 164 0.097
negative regulation of viral process GO:0048525 66 0.096
Human
protein secretion GO:0009306 98 0.093
Human
positive regulation of phosphorylation GO:0042327 394 0.090
Human
adaptive immune response GO:0002250 49 0.088
Human
innate immune response activating signal transduction GO:0002758 48 0.087
Human
cellular response to cytokine stimulus GO:0071345 181 0.087
negative regulation of calcium ion import GO:0090281 1 0.086
Human
nuclear transport GO:0051169 179 0.086
positive regulation of hydrolase activity GO:0051345 331 0.084
regulation of viral process GO:0050792 103 0.083
Human
positive regulation of proteolysis GO:0045862 142 0.083
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.082
Human
response to oxygen containing compound GO:1901700 369 0.082
Human
cellular response to molecule of bacterial origin GO:0071219 62 0.081
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.077
positive regulation of rig i signaling pathway GO:1900246 4 0.075
Human
response to nitrogen compound GO:1901698 184 0.074
regulation of lymphocyte activation GO:0051249 103 0.074
regulation of cell cycle GO:0051726 393 0.071
Human
negative regulation of protein metabolic process GO:0051248 391 0.070
Human
i kappab kinase nf kappab signaling GO:0007249 166 0.070
mononuclear cell proliferation GO:0032943 71 0.070
response to lipid GO:0033993 206 0.066
Human
regulation of mononuclear cell proliferation GO:0032944 65 0.066
regulation of immune effector process GO:0002697 91 0.064
Human
cellular response to external stimulus GO:0071496 111 0.064
positive regulation of cellular component organization GO:0051130 376 0.064
Human
regulation of cell differentiation GO:0045595 393 0.063
regulation of protein transport GO:0051223 213 0.062
Human
positive regulation of leukocyte activation GO:0002696 80 0.058
organophosphate catabolic process GO:0046434 430 0.057
regulation of peptidase activity GO:0052547 180 0.057
positive regulation of programmed cell death GO:0043068 249 0.056
Human
negative regulation of immune response GO:0050777 40 0.056
Human
detection of muramyl dipeptide GO:0032498 1 0.054
cellular response to lipid GO:0071396 127 0.054
Human
negative regulation of intracellular transport GO:0032387 60 0.052
Human
regulation of protein maturation GO:1903317 150 0.052
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.051
Human
regulation of intracellular transport GO:0032386 195 0.051
Human
regulation of interleukin 1 secretion GO:0050704 14 0.051
negative regulation of transport GO:0051051 176 0.051
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.051
Human
apoptotic signaling pathway GO:0097190 268 0.050
Human
response to interferon beta GO:0035456 11 0.049
regulation of protein localization GO:0032880 296 0.049
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.049
Human
negative regulation of cell proliferation GO:0008285 228 0.048
protein oligomerization GO:0051259 173 0.047
positive regulation of cell differentiation GO:0045597 211 0.047
negative regulation of proteolysis GO:0045861 132 0.047
Human
response to abiotic stimulus GO:0009628 336 0.046
negative regulation of defense response GO:0031348 47 0.046
regulation of protein oligomerization GO:0032459 26 0.046
negative regulation of endopeptidase activity GO:0010951 84 0.046
purine containing compound catabolic process GO:0072523 411 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
detection of chemical stimulus GO:0009593 55 0.045
regulation of secretion by cell GO:1903530 177 0.045
Human
positive regulation of intracellular transport GO:0032388 104 0.045
regulation of endopeptidase activity GO:0052548 170 0.043
cytokine mediated signaling pathway GO:0019221 109 0.043
negative regulation of hydrolase activity GO:0051346 182 0.042
positive regulation of leukocyte differentiation GO:1902107 37 0.042
negative regulation of cell cycle GO:0045786 193 0.041
cytoplasmic transport GO:0016482 379 0.041
response to lipopolysaccharide GO:0032496 70 0.041
Human
regulation of transferase activity GO:0051338 355 0.041
Human
viral genome replication GO:0019079 50 0.041
positive regulation of multi organism process GO:0043902 56 0.041
Human
purine ribonucleotide catabolic process GO:0009154 404 0.041
regulation of cellular component biogenesis GO:0044087 281 0.040
Human
positive regulation of transport GO:0051050 336 0.040
immune system development GO:0002520 195 0.039
organonitrogen compound biosynthetic process GO:1901566 200 0.039
regulation of interleukin 1 production GO:0032652 21 0.039
fas signaling pathway GO:0036337 3 0.039
positive regulation of response to biotic stimulus GO:0002833 18 0.039
Human
interleukin 1 production GO:0032612 26 0.038
angiogenesis GO:0001525 147 0.038
positive regulation of protein secretion GO:0050714 60 0.038
secretion GO:0046903 254 0.038
Human
negative regulation of viral transcription GO:0032897 23 0.037
Human
cytokine secretion GO:0050663 64 0.037
Human
regulation of fas signaling pathway GO:1902044 2 0.037
positive regulation of protein transport GO:0051222 135 0.036
system process GO:0003008 349 0.036
regulation of cysteine type endopeptidase activity GO:2000116 127 0.036
response to peptidoglycan GO:0032494 3 0.036
negative regulation of multi organism process GO:0043901 92 0.035
Human
interleukin 2 secretion GO:0070970 3 0.035
Human
positive regulation of interferon beta production GO:0032728 17 0.035
nucleotide catabolic process GO:0009166 408 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
anatomical structure homeostasis GO:0060249 100 0.033
blood vessel morphogenesis GO:0048514 162 0.033
memory GO:0007613 3 0.033
spermatid development GO:0007286 4 0.033
cellular response to dna damage stimulus GO:0006974 379 0.032
nucleoside triphosphate metabolic process GO:0009141 422 0.032
purine nucleoside catabolic process GO:0006152 398 0.032
regulation of cell activation GO:0050865 125 0.032
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.031
positive regulation of secretion GO:0051047 116 0.031
positive regulation of intracellular protein transport GO:0090316 76 0.031
autophagy GO:0006914 88 0.031
regulation of nucleocytoplasmic transport GO:0046822 98 0.030
negative regulation of multicellular organismal process GO:0051241 317 0.030
Human
negative regulation of cellular component organization GO:0051129 235 0.030
regulation of defense response to virus by host GO:0050691 22 0.030
negative regulation of protein processing GO:0010955 142 0.029
Human
ribonucleoside catabolic process GO:0042454 406 0.028
positive regulation of apoptotic signaling pathway GO:2001235 70 0.028
Human
zymogen activation GO:0031638 70 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
Human
interleukin 1 secretion GO:0050701 18 0.027
ribonucleoside triphosphate catabolic process GO:0009203 391 0.027
entry into host GO:0044409 25 0.027
Human
regulation of protein complex assembly GO:0043254 147 0.027
Human
regulation of mapk cascade GO:0043408 262 0.026
Human
determination of adult lifespan GO:0008340 2 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
Human
leukocyte differentiation GO:0002521 98 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
calcium ion import GO:0070509 23 0.026
Human
intracellular protein transport GO:0006886 270 0.026
cellular protein catabolic process GO:0044257 261 0.025
Human
cytokine metabolic process GO:0042107 38 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
Human
protein catabolic process GO:0030163 325 0.025
Human
cellular response to biotic stimulus GO:0071216 71 0.025
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
positive regulation of interleukin 1 production GO:0032732 14 0.024
regulation of dna binding GO:0051101 37 0.024
myeloid cell differentiation GO:0030099 117 0.024
positive regulation of response to external stimulus GO:0032103 88 0.024
Human
positive regulation of secretion by cell GO:1903532 108 0.024
interleukin 1 beta production GO:0032611 22 0.024
pyroptosis GO:0070269 1 0.024
nucleoside triphosphate catabolic process GO:0009143 394 0.024
cell cycle arrest GO:0007050 71 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.023
humoral immune response GO:0006959 49 0.023
regulation of tumor necrosis factor production GO:0032680 43 0.023
Human
response to drug GO:0042493 81 0.023
positive regulation of organelle organization GO:0010638 195 0.023
Human
negative regulation of phosphorylation GO:0042326 174 0.023
Human
osteoblast differentiation GO:0001649 92 0.023
nucleocytoplasmic transport GO:0006913 176 0.023
protein modification by small protein conjugation GO:0032446 342 0.023
Human
regulation of binding GO:0051098 111 0.022
regulation of secretion GO:0051046 194 0.022
Human
negative regulation of cytokine production GO:0001818 82 0.022
Human
response to mechanical stimulus GO:0009612 51 0.022
protein ubiquitination GO:0016567 314 0.022
Human
myeloid leukocyte differentiation GO:0002573 60 0.022
endosomal transport GO:0016197 129 0.022
Human
response to dsrna GO:0043331 25 0.022
cellular macromolecule catabolic process GO:0044265 380 0.021
Human
multi organism metabolic process GO:0044033 41 0.021
Human
autophagic cell death GO:0048102 3 0.021
regulation of kinase activity GO:0043549 314 0.021
Human
cellular protein complex assembly GO:0043623 188 0.021
Human
protein autoubiquitination GO:0051865 37 0.021
Human
protein targeting GO:0006605 187 0.021
positive regulation of interleukin 1 beta production GO:0032731 13 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
protein deubiquitination GO:0016579 79 0.021
Human
syncytium formation by plasma membrane fusion GO:0000768 2 0.020
negative regulation of interleukin 2 secretion GO:1900041 2 0.020
Human
lymphocyte activation GO:0046649 133 0.020
positive regulation of interferon alpha production GO:0032727 11 0.020
cellular response to organic cyclic compound GO:0071407 127 0.020
negative regulation of protein transport GO:0051224 75 0.020
Human
positive regulation of type i interferon production GO:0032481 20 0.020
Human
ribonucleotide catabolic process GO:0009261 405 0.020
regulation of cytoskeleton organization GO:0051493 177 0.020
Human
cellular response to oxygen containing compound GO:1901701 276 0.020
Human
negative regulation of protein phosphorylation GO:0001933 140 0.020
Human
cation transport GO:0006812 331 0.020
Human
multicellular organismal aging GO:0010259 3 0.020
regulation of interleukin 6 production GO:0032675 37 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
response to tumor necrosis factor GO:0034612 76 0.019
response to interferon alpha GO:0035455 11 0.019
ion transmembrane transport GO:0034220 338 0.019
Human
signal transduction by p53 class mediator GO:0072331 72 0.019
production of molecular mediator of immune response GO:0002440 37 0.018
positive regulation of mapk cascade GO:0043410 190 0.018
Human
negative regulation of peptidase activity GO:0010466 91 0.018
cellular response to mechanical stimulus GO:0071260 39 0.018
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.018
response to organonitrogen compound GO:0010243 156 0.018
regulation of cellular response to stress GO:0080135 244 0.018
melanin metabolic process GO:0006582 1 0.018
regulation of t cell activation GO:0050863 77 0.018
regulation of gene expression epigenetic GO:0040029 73 0.018
Human
compound eye development GO:0048749 1 0.018
peripheral nervous system development GO:0007422 2 0.017
negative regulation of protein secretion GO:0050709 29 0.017
Human
response to muramyl dipeptide GO:0032495 4 0.017
positive regulation of catabolic process GO:0009896 310 0.017
regulation of autophagy GO:0010506 52 0.017
secretion by cell GO:0032940 226 0.017
Human
regulation of osteoblast differentiation GO:0045667 38 0.017
protein localization to organelle GO:0033365 280 0.017
protein autoprocessing GO:0016540 4 0.017
regulation of leukocyte proliferation GO:0070663 67 0.017
regulation of protein localization to nucleus GO:1900180 85 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
positive regulation of cell cycle GO:0045787 140 0.016
Human
female gamete generation GO:0007292 2 0.016
ribonucleoside monophosphate metabolic process GO:0009161 187 0.016
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.016
mitotic cell cycle process GO:1903047 286 0.016
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.016
regulation of interleukin 1 beta production GO:0032651 18 0.015
positive regulation of lymphocyte activation GO:0051251 73 0.015
positive regulation of kinase activity GO:0033674 204 0.015
rna interference GO:0016246 4 0.015
negative regulation of binding GO:0051100 57 0.015
cardiovascular system development GO:0072358 262 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
Human
modification dependent protein catabolic process GO:0019941 209 0.015
Human
generation of neurons GO:0048699 152 0.015
neurological system process GO:0050877 163 0.015
spermatid differentiation GO:0048515 4 0.015
purine nucleotide catabolic process GO:0006195 405 0.015
actin filament based process GO:0030029 224 0.015
Human
regulation of b cell activation GO:0050864 24 0.015
protein import into nucleus GO:0006606 104 0.015
viral transcription GO:0019083 35 0.015
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
Human
response to interferon gamma GO:0034341 39 0.014
regulation of protein kinase activity GO:0045859 289 0.014
Human
vasculature development GO:0001944 181 0.014
transmembrane transport GO:0055085 399 0.014
Human
b cell activation GO:0042113 33 0.014
lymphocyte differentiation GO:0030098 35 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
cellular response to radiation GO:0071478 65 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.013
peptide metabolic process GO:0006518 51 0.013
negative regulation of cell motility GO:2000146 104 0.013
cellular response to abiotic stimulus GO:0071214 117 0.013
cellular response to lipopolysaccharide GO:0071222 57 0.013
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
cell development GO:0048468 328 0.013
protein import GO:0017038 130 0.013
regulation of cellular protein catabolic process GO:1903362 96 0.013
Human
regulation of cell cycle phase transition GO:1901987 126 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.013
vesicle mediated transport GO:0016192 371 0.013
Human
interferon gamma production GO:0032609 39 0.013
Human
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
regulation of vasculature development GO:1901342 97 0.013
mitotic cell cycle GO:0000278 326 0.013
single organism cellular localization GO:1902580 332 0.013
membrane hyperpolarization GO:0060081 1 0.013
nucleoside monophosphate catabolic process GO:0009125 159 0.013
viral gene expression GO:0019080 35 0.013
Human
oogenesis GO:0048477 2 0.013
cell cycle checkpoint GO:0000075 117 0.013
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.013
Human
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
positive regulation of cell activation GO:0050867 81 0.013
regulation of adaptive immune response GO:0002819 33 0.012
Human
organophosphate biosynthetic process GO:0090407 163 0.012
positive regulation of protein oligomerization GO:0032461 17 0.012
positive regulation of stress activated mapk cascade GO:0032874 60 0.012
response to organic cyclic compound GO:0014070 204 0.012
regulation of endothelial cell migration GO:0010594 67 0.012
regulation of protein deubiquitination GO:0090085 4 0.012
Human
cellular response to nitrogen compound GO:1901699 144 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.012
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.012
Human
myoblast fusion GO:0007520 1 0.012
regulation of rig i signaling pathway GO:0039535 6 0.012
Human
regulation of actin filament based process GO:0032970 141 0.012
Human
protein targeting to nucleus GO:0044744 104 0.012
regulation of cell migration GO:0030334 289 0.011
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.011
Human
regulation of cellular component size GO:0032535 82 0.011
Human
negative regulation of transferase activity GO:0051348 124 0.011
Human
negative regulation of programmed cell death GO:0043069 321 0.011
cell fate determination GO:0001709 3 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
positive regulation of protein import into nucleus GO:0042307 46 0.011
negative regulation of secretion GO:0051048 58 0.011
Human
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.011
regulation of protein targeting GO:1903533 91 0.011
midgut development GO:0007494 1 0.011
neuron projection regeneration GO:0031102 1 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
Human
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
regulation of interleukin 2 secretion GO:1900040 2 0.011
Human
regulation of locomotion GO:0040012 329 0.010
Human
circadian behavior GO:0048512 2 0.010
post embryonic development GO:0009791 2 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.010
regulation of metal ion transport GO:0010959 120 0.010
Human
nucleoside phosphate catabolic process GO:1901292 412 0.010
cellular response to nutrient levels GO:0031669 69 0.010
central nervous system development GO:0007417 123 0.010
stress activated protein kinase signaling cascade GO:0031098 94 0.010
signal transduction in response to dna damage GO:0042770 57 0.010
activation of cysteine type endopeptidase activity GO:0097202 57 0.010
cellular amide metabolic process GO:0043603 69 0.010
carbohydrate derivative biosynthetic process GO:1901137 207 0.010
negative regulation of kinase activity GO:0033673 106 0.010
Human
negative regulation of cytokine secretion GO:0050710 20 0.010
Human
negative regulation of mitotic cell cycle GO:0045930 102 0.010
cell part morphogenesis GO:0032990 137 0.010
neuron projection development GO:0031175 106 0.010

TRIM22 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.012