Homo sapiens

11 known processes

HGD

homogentisate 1,2-dioxygenase

(Aliases: HGO,FLJ94126,AKU)

HGD biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 185 0.228
lipid metabolic process GO:0006629 381 0.184
cellular lipid metabolic process GO:0044255 303 0.182
cellular amino acid metabolic process GO:0006520 116 0.166
oxidation reduction process GO:0055114 396 0.165
vitamin k catabolic process GO:0042377 2 0.108
organic hydroxy compound metabolic process GO:1901615 147 0.096
sulfur compound metabolic process GO:0006790 101 0.088
cellular amine metabolic process GO:0044106 41 0.077
small molecule biosynthetic process GO:0044283 157 0.077
fatty acid metabolic process GO:0006631 115 0.067
cellular ketone metabolic process GO:0042180 80 0.061
post embryonic development GO:0009791 2 0.057
steroid metabolic process GO:0008202 94 0.053
cellular modified amino acid metabolic process GO:0006575 64 0.052
amine metabolic process GO:0009308 44 0.052
quinone catabolic process GO:1901662 2 0.051
coenzyme metabolic process GO:0006732 65 0.051
protein maturation GO:0051604 233 0.050
epoxygenase p450 pathway GO:0019373 3 0.050
negative regulation of protein metabolic process GO:0051248 391 0.050
icosanoid catabolic process GO:1901523 2 0.049
small molecule catabolic process GO:0044282 92 0.048
protein processing GO:0016485 226 0.048
regulation of cellular amine metabolic process GO:0033238 11 0.048
carboxylic acid biosynthetic process GO:0046394 97 0.045
regulation of cellular ketone metabolic process GO:0010565 50 0.044
chemical homeostasis GO:0048878 306 0.044
cofactor metabolic process GO:0051186 87 0.044
phylloquinone metabolic process GO:0042374 2 0.044
regulation of hormone levels GO:0010817 125 0.043
response to oxygen containing compound GO:1901700 369 0.043
urea metabolic process GO:0019627 3 0.043
lipid biosynthetic process GO:0008610 177 0.043
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
lipid catabolic process GO:0016042 84 0.042
organic anion transport GO:0015711 103 0.041
organic acid catabolic process GO:0016054 71 0.041
organic acid biosynthetic process GO:0016053 97 0.039
menaquinone metabolic process GO:0009233 3 0.039
system process GO:0003008 349 0.038
negative regulation of icosanoid secretion GO:0032304 2 0.038
multicellular organismal aging GO:0010259 3 0.037
determination of adult lifespan GO:0008340 2 0.037
carboxylic acid catabolic process GO:0046395 71 0.036
alcohol metabolic process GO:0006066 114 0.035
fatty acid omega oxidation GO:0010430 2 0.035
cellular response to oxygen containing compound GO:1901701 276 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
response to biotic stimulus GO:0009607 276 0.031
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
cellular lipid catabolic process GO:0044242 65 0.030
leukotriene b4 metabolic process GO:0036102 2 0.030
regulation of body fluid levels GO:0050878 99 0.030
regeneration GO:0031099 4 0.029
long chain fatty acid metabolic process GO:0001676 30 0.029
alkaloid metabolic process GO:0009820 4 0.029
anion transport GO:0006820 161 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
carbohydrate metabolic process GO:0005975 207 0.028
hormone metabolic process GO:0042445 61 0.028
cellular response to genistein GO:0071412 1 0.028
defense response GO:0006952 315 0.027
response to hormone GO:0009725 175 0.027
response to abiotic stimulus GO:0009628 336 0.027
vitamin k biosynthetic process GO:0042371 2 0.026
response to lipid GO:0033993 206 0.026
regulation of proteolysis GO:0030162 293 0.026
sensory perception of smell GO:0007608 2 0.026
cation transport GO:0006812 331 0.026
positive regulation of transport GO:0051050 336 0.026
immune response GO:0006955 307 0.026
single organism carbohydrate metabolic process GO:0044723 193 0.025
icosanoid metabolic process GO:0006690 35 0.025
cellular amide metabolic process GO:0043603 69 0.025
lipid modification GO:0030258 84 0.025
response to other organism GO:0051707 261 0.025
apoptotic signaling pathway GO:0097190 268 0.024
coagulation GO:0050817 78 0.024
alpha amino acid metabolic process GO:1901605 72 0.024
response to inorganic substance GO:0010035 127 0.024
cell adhesion GO:0007155 325 0.024
regulation of response to external stimulus GO:0032101 222 0.024
unsaturated fatty acid metabolic process GO:0033559 37 0.023
vitamin e metabolic process GO:0042360 1 0.023
response to external biotic stimulus GO:0043207 261 0.023
menaquinone catabolic process GO:0042361 2 0.023
ion homeostasis GO:0050801 230 0.023
regulation of protein maturation GO:1903317 150 0.022
female gamete generation GO:0007292 2 0.022
lipid transport GO:0006869 90 0.022
biological adhesion GO:0022610 331 0.022
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
response to metal ion GO:0010038 84 0.022
response to organic cyclic compound GO:0014070 204 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
cellular response to xenobiotic stimulus GO:0071466 29 0.021
regulation of protein processing GO:0070613 150 0.021
fatty acid derivative metabolic process GO:1901568 35 0.021
hemostasis GO:0007599 76 0.021
cellular response to hydroxyisoflavone GO:0071413 1 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
regulation of kinase activity GO:0043549 314 0.020
positive regulation of catabolic process GO:0009896 310 0.020
secretion GO:0046903 254 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
purine containing compound catabolic process GO:0072523 411 0.020
negative regulation of protein maturation GO:1903318 142 0.020
positive regulation of secretion GO:0051047 116 0.019
positive regulation of immune system process GO:0002684 283 0.019
monocarboxylic acid biosynthetic process GO:0072330 67 0.019
organonitrogen compound biosynthetic process GO:1901566 200 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
oogenesis GO:0048477 2 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
response to bacterium GO:0009617 144 0.019
transmembrane transport GO:0055085 399 0.019
purine ribonucleoside metabolic process GO:0046128 437 0.019
regulation of peptidase activity GO:0052547 180 0.019
negative regulation of protein processing GO:0010955 142 0.019
nitrogen cycle metabolic process GO:0071941 3 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
organophosphate catabolic process GO:0046434 430 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.019
protein catabolic process GO:0030163 325 0.019
leukotriene catabolic process GO:0036100 2 0.018
negative regulation of proteolysis GO:0045861 132 0.018
terpenoid metabolic process GO:0006721 27 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
organic acid transport GO:0015849 65 0.018
isoprenoid metabolic process GO:0006720 39 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
segmentation GO:0035282 4 0.018
naphthalene metabolic process GO:0018931 1 0.018
oxidative demethylation GO:0070989 11 0.018
purine nucleoside triphosphate catabolic process GO:0009146 392 0.018
nucleotide catabolic process GO:0009166 408 0.017
wound healing GO:0042060 115 0.017
innate immune response GO:0045087 178 0.017
regulation of cell differentiation GO:0045595 393 0.017
glycerolipid metabolic process GO:0046486 107 0.017
renal water homeostasis GO:0003091 4 0.017
locomotory behavior GO:0007626 1 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
positive regulation of phosphorylation GO:0042327 394 0.017
leukotriene b4 catabolic process GO:0036101 2 0.017
cellular response to dna damage stimulus GO:0006974 379 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.017
drug metabolic process GO:0017144 19 0.017
spermatid differentiation GO:0048515 4 0.017
response to xenobiotic stimulus GO:0009410 30 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
regulation of cellular response to stress GO:0080135 244 0.017
memory GO:0007613 3 0.017
linoleic acid metabolic process GO:0043651 4 0.017
alkaloid catabolic process GO:0009822 3 0.017
lipid localization GO:0010876 106 0.016
neuromuscular junction development GO:0007528 3 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
cytoplasmic transport GO:0016482 379 0.016
regulation of defense response GO:0031347 154 0.016
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
membrane organization GO:0061024 292 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
lipid oxidation GO:0034440 33 0.016
cation homeostasis GO:0055080 189 0.016
cardiac muscle cell contraction GO:0086003 4 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
organic hydroxy compound biosynthetic process GO:1901617 71 0.016
isoquinoline alkaloid metabolic process GO:0033076 1 0.016
regulation of cell cycle GO:0051726 393 0.016
regulation of protein localization GO:0032880 296 0.016
peptide metabolic process GO:0006518 51 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
regulation of transferase activity GO:0051338 355 0.016
single organism membrane organization GO:0044802 268 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
response to fungus GO:0009620 4 0.015
nitrogen compound transport GO:0071705 191 0.015
phylloquinone catabolic process GO:0042376 2 0.015
negative regulation of cell death GO:0060548 345 0.015
estrogen catabolic process GO:0006711 1 0.015
actin filament based process GO:0030029 224 0.015
mitotic cell cycle GO:0000278 326 0.015
response to steroid hormone GO:0048545 80 0.015
regulation of cellular component movement GO:0051270 334 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
vesicle mediated transport GO:0016192 371 0.015
glycoprotein metabolic process GO:0009100 110 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
ketone catabolic process GO:0042182 3 0.015
regulation of response to wounding GO:1903034 101 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
response to drug GO:0042493 81 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
small gtpase mediated signal transduction GO:0007264 78 0.015
negative regulation of protein modification process GO:0031400 200 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
nucleoside catabolic process GO:0009164 408 0.014
response to nutrient levels GO:0031667 81 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
dephosphorylation GO:0016311 209 0.014
ras protein signal transduction GO:0007265 73 0.014
nerve development GO:0021675 4 0.014
ribonucleoside catabolic process GO:0042454 406 0.014
regulation of cell motility GO:2000145 299 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
cell morphogenesis GO:0000902 296 0.014
spermatid development GO:0007286 4 0.014
defense response to other organism GO:0098542 129 0.014
response to extracellular stimulus GO:0009991 85 0.014
oocyte development GO:0048599 1 0.014
epithelium development GO:0060429 227 0.014
maintenance of location GO:0051235 112 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
blastoderm segmentation GO:0007350 2 0.014
peripheral nervous system development GO:0007422 2 0.014
salivary gland morphogenesis GO:0007435 4 0.014
cell growth GO:0016049 160 0.014
mitotic cell cycle process GO:1903047 286 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
protein oligomerization GO:0051259 173 0.014
metal ion transport GO:0030001 272 0.014
fatty acid derivative catabolic process GO:1901569 2 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
tissue regeneration GO:0042246 3 0.014
cellular protein catabolic process GO:0044257 261 0.014
cellular protein complex assembly GO:0043623 188 0.014
positive regulation of immune response GO:0050778 159 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.013
mapk cascade GO:0000165 288 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
mitochondrion organization GO:0007005 156 0.013
inner ear morphogenesis GO:0042472 4 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
atp metabolic process GO:0046034 176 0.013
negative regulation of transferase activity GO:0051348 124 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
oocyte differentiation GO:0009994 2 0.013
response to wounding GO:0009611 168 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
response to nitrogen compound GO:1901698 184 0.013
cell fate determination GO:0001709 3 0.013
carboxylic acid transport GO:0046942 63 0.013
cation transmembrane transport GO:0098655 238 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
epithelial cell differentiation GO:0030855 141 0.013
water homeostasis GO:0030104 14 0.013
regulation of immune response GO:0050776 201 0.013
purine nucleoside monophosphate metabolic process GO:0009126 186 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
defense response to fungus GO:0050832 4 0.013
immune effector process GO:0002252 159 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
regulation of secretion GO:0051046 194 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
rho protein signal transduction GO:0007266 26 0.013
negative regulation of cell proliferation GO:0008285 228 0.013
negative regulation of developmental process GO:0051093 247 0.013
arachidonic acid metabolic process GO:0019369 14 0.013
growth GO:0040007 202 0.013
regulation of protein kinase activity GO:0045859 289 0.013
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
single organism cellular localization GO:1902580 332 0.013
cellular amino acid catabolic process GO:0009063 31 0.013
regulation of protein catabolic process GO:0042176 155 0.012
tripartite regional subdivision GO:0007351 2 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
regulation of wound healing GO:0061041 56 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
glutathione metabolic process GO:0006749 20 0.012
protein localization to organelle GO:0033365 280 0.012
regulation of blood coagulation GO:0030193 42 0.012
regulation of cell cycle process GO:0010564 266 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
protein targeting GO:0006605 187 0.012
actin mediated cell contraction GO:0070252 12 0.012
response to decreased oxygen levels GO:0036293 96 0.012
negative regulation of peptidase activity GO:0010466 91 0.012
negative regulation of kinase activity GO:0033673 106 0.012
cellular component disassembly GO:0022411 92 0.012
interspecies interaction between organisms GO:0044419 156 0.012
regulation of cytokine production GO:0001817 232 0.012
ion transmembrane transport GO:0034220 338 0.012
secretion by cell GO:0032940 226 0.012
regulation of mapk cascade GO:0043408 262 0.012
rhythmic behavior GO:0007622 2 0.012
anterior posterior axis specification GO:0009948 2 0.012
positive regulation of proteolysis GO:0045862 142 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
hindbrain development GO:0030902 3 0.012
response to organonitrogen compound GO:0010243 156 0.012
rna processing GO:0006396 255 0.012
positive regulation of cell death GO:0010942 263 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
zymogen activation GO:0031638 70 0.012
negative regulation of endopeptidase activity GO:0010951 84 0.012
diterpenoid metabolic process GO:0016101 20 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
blood coagulation GO:0007596 76 0.012
primary alcohol metabolic process GO:0034308 17 0.011
actin filament based movement GO:0030048 17 0.011
adult locomotory behavior GO:0008344 1 0.011
chromatin organization GO:0006325 351 0.011
naphthalene containing compound metabolic process GO:0090420 1 0.011
intracellular protein transport GO:0006886 270 0.011
sensory perception GO:0007600 103 0.011
cell junction organization GO:0034330 79 0.011
cytokine production GO:0001816 247 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
sensory perception of chemical stimulus GO:0007606 38 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
circulatory system development GO:0072359 262 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
cellular response to external stimulus GO:0071496 111 0.011
monosaccharide metabolic process GO:0005996 74 0.011
negative regulation of response to wounding GO:1903035 47 0.011
myoblast fusion GO:0007520 1 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
organ formation GO:0048645 3 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
cell cell junction organization GO:0045216 69 0.011
compound eye development GO:0048749 1 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
response to hypoxia GO:0001666 96 0.011
cell projection assembly GO:0030031 126 0.011
microtubule based process GO:0007017 210 0.011
positive regulation of organic acid transport GO:0032892 3 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
cellular response to lipid GO:0071396 127 0.011
cellular hormone metabolic process GO:0034754 41 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
cellular response to hormone stimulus GO:0032870 125 0.011
regulation of secretion by cell GO:1903530 177 0.011
regulation of coagulation GO:0050818 44 0.011
nervous system development GO:0007399 293 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
regulation of protein transport GO:0051223 213 0.011
cellular organohalogen metabolic process GO:0090345 2 0.011
cell projection organization GO:0030030 252 0.011
response to axon injury GO:0048678 1 0.011
alpha amino acid catabolic process GO:1901606 26 0.010
pressure natriuresis GO:0003095 2 0.010
neurological system process GO:0050877 163 0.010
phospholipid metabolic process GO:0006644 99 0.010
endocytosis GO:0006897 159 0.010
ubiquitin dependent protein catabolic process GO:0006511 206 0.010
positive regulation of cell migration GO:0030335 172 0.010
regulation of locomotion GO:0040012 329 0.010
positive regulation of developmental process GO:0051094 314 0.010
histone modification GO:0016570 251 0.010
protein homooligomerization GO:0051260 100 0.010
cell substrate adhesion GO:0031589 132 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.010
actin cytoskeleton organization GO:0030036 207 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010
cellular homeostasis GO:0019725 196 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
regulation of cell growth GO:0001558 135 0.010
retinoic acid biosynthetic process GO:0002138 2 0.010
organ morphogenesis GO:0009887 147 0.010
long chain fatty acid catabolic process GO:0042758 3 0.010
circadian behavior GO:0048512 2 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
covalent chromatin modification GO:0016569 254 0.010
regulation of growth GO:0040008 165 0.010
peptidyl lysine modification GO:0018205 144 0.010

HGD disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.084
inherited metabolic disorder DOID:655 242 0.057
immune system disease DOID:2914 155 0.024
amino acid metabolic disorder DOID:9252 50 0.021
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
hematopoietic system disease DOID:74 100 0.017
sensory system disease DOID:0050155 203 0.017
nervous system disease DOID:863 431 0.017
organ system cancer DOID:0050686 164 0.016
musculoskeletal system disease DOID:17 223 0.015
central nervous system disease DOID:331 186 0.013
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.012
cardiovascular system disease DOID:1287 106 0.012
connective tissue disease DOID:65 109 0.011
neurodegenerative disease DOID:1289 102 0.011
retinal disease DOID:5679 118 0.010
organic acidemia DOID:0060159 14 0.002