|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.967
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.952
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.924
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.923
|
Human Yeast |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.921
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.839
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.796
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.783
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.774
|
|
|
|
spliceosomal snrnp assembly
|
GO:0000387 |
28 |
0.755
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.747
|
Human Yeast |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.739
|
Human Yeast |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.699
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.689
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.582
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.581
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.560
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.533
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.506
|
Human Yeast |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.494
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.493
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.469
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.468
|
Human Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.409
|
Human Yeast |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.386
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.368
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.321
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.318
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.310
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.294
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.264
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.252
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.244
|
Human Yeast |
|
|
protein maturation
|
GO:0051604 |
233 |
0.240
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
0.240
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.237
|
Human |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.233
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.226
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.224
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.209
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.197
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.193
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.193
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.191
|
Yeast |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.188
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.184
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.183
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.177
|
Yeast |
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.177
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.172
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.171
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.169
|
|
|
|
monoubiquitinated protein deubiquitination
|
GO:0035520 |
6 |
0.169
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.168
|
Yeast |
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.165
|
|
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.165
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.165
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.164
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.159
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.153
|
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
31 |
0.152
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.145
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.145
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.142
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.142
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.140
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.139
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.137
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.137
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.135
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.135
|
Yeast |
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.134
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.134
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.133
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.133
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.132
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.126
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.126
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.124
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.123
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.121
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.120
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.118
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.115
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.115
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.112
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.111
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.111
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.109
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.108
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.108
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.107
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.106
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.105
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.104
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.100
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.099
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.097
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.097
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.096
|
|
|
|
mitochondrial outer membrane permeabilization
|
GO:0097345 |
15 |
0.096
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.096
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.095
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.094
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.094
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.094
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.094
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.093
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.093
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.093
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.092
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.092
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.091
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.091
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.090
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.089
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.089
|
|
|
|
growth
|
GO:0040007 |
202 |
0.087
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.087
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.085
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.084
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.083
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.083
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.082
|
Yeast |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.082
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.082
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.082
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.081
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.081
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.080
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
89 |
0.078
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.078
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.078
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.076
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.076
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.075
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.075
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.075
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.075
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.074
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.073
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.072
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.072
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.071
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.071
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.070
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.069
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.069
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.069
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.069
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.068
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.068
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.068
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.067
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.067
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.066
|
|
|
|
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
|
GO:0001844 |
2 |
0.066
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.066
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.066
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.065
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.064
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.064
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.064
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.062
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.062
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.062
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.062
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.061
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.061
|
|
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
16 |
0.061
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.060
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.059
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.058
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.058
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.058
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.058
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.057
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.057
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.057
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.057
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.056
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.056
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.056
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.055
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.055
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.055
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.054
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.054
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.054
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.054
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.053
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.051
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.051
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.051
|
|
|
|
histone h2b conserved c terminal lysine deubiquitination
|
GO:0035616 |
1 |
0.051
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.050
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.050
|
|
|
|
fibroblast apoptotic process
|
GO:0044346 |
8 |
0.050
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.050
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.050
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.050
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.049
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.049
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.049
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.049
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.049
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.049
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.049
|
Yeast |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.048
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.048
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.048
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.048
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.047
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.047
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.046
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.046
|
|
|
|
embryonic digit morphogenesis
|
GO:0042733 |
6 |
0.046
|
|
|
|
negative regulation of fibroblast proliferation
|
GO:0048147 |
12 |
0.046
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.046
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.046
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.046
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.045
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.045
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.045
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.045
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.044
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.044
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.044
|
|
|
|
neuron death in response to oxidative stress
|
GO:0036475 |
9 |
0.044
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.044
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.044
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.044
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.043
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.043
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.042
|
Yeast |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.042
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.042
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.042
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.041
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.041
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.041
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.041
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.041
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.041
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.041
|
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.041
|
Human |
|
|
mitochondrial fragmentation involved in apoptotic process
|
GO:0043653 |
7 |
0.040
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.040
|
|
|
|
modulation by virus of host process
|
GO:0019054 |
2 |
0.040
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.040
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.040
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.039
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.038
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.038
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.038
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.038
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.038
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.038
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.038
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.037
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.037
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
16 |
0.037
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.037
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.037
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.037
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.037
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.037
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.036
|
|
|
|
regulation of oxidative stress induced neuron death
|
GO:1903203 |
9 |
0.036
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.036
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.036
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.036
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.035
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.035
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.034
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.034
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.034
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.034
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.034
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
2 |
0.034
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.034
|
|
|
|
positive regulation of signal transduction by p53 class mediator
|
GO:1901798 |
10 |
0.034
|
|
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
17 |
0.034
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.033
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.033
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.033
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.033
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.033
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.033
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.032
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.032
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.032
|
|
|
|
histone deubiquitination
|
GO:0016578 |
16 |
0.032
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.031
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.031
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.031
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.031
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.031
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.031
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.031
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.031
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.030
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.030
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.030
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.030
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.030
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.030
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.030
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.029
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.029
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.029
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.029
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.029
|
|
|
|
positive regulation of oxidative stress induced cell death
|
GO:1903209 |
5 |
0.028
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.028
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.028
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.028
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.028
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.028
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.028
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.027
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.027
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.027
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.027
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.026
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.026
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.026
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.026
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.026
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.026
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.026
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.026
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.026
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.025
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.025
|
|
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.025
|
|
|
|
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902177 |
4 |
0.025
|
|
|
|
regulation of apoptotic dna fragmentation
|
GO:1902510 |
3 |
0.025
|
|
|
|
spliceosomal tri snrnp complex assembly
|
GO:0000244 |
7 |
0.025
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.025
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.025
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.025
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.025
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.025
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.025
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.025
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.024
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.024
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.024
|
|
|
|
positive regulation of apoptotic dna fragmentation
|
GO:1902512 |
1 |
0.024
|
|
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.024
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.024
|
|
|
|
positive regulation of endoplasmic reticulum unfolded protein response
|
GO:1900103 |
4 |
0.023
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.023
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.023
|
|
|
|
aging
|
GO:0007568 |
66 |
0.023
|
|
|
|
negative regulation of cell division
|
GO:0051782 |
31 |
0.023
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.023
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.023
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.023
|
|
|
|
golgi organization
|
GO:0007030 |
38 |
0.023
|
Human |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.022
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.022
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.022
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.022
|
|
|
|
positive regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043517 |
8 |
0.022
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.022
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.022
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.022
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.022
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.021
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.021
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.021
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.021
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.021
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.021
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.021
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.021
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.021
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.020
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.020
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.020
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.020
|
|
|
|
spindle checkpoint
|
GO:0031577 |
26 |
0.020
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.020
|
|
|
|
regulation of endoplasmic reticulum unfolded protein response
|
GO:1900101 |
5 |
0.020
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.020
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.020
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.020
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.020
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.019
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.019
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.019
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.019
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.019
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.019
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.019
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.019
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.019
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.019
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.019
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.019
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.019
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.019
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.019
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.018
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.018
|
Human |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.018
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.018
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.018
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.018
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.018
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.018
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
|
GO:0070059 |
12 |
0.018
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.018
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.018
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.018
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.018
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.018
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.018
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.018
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.018
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.018
|
|
|
|
regulation of oxidative phosphorylation
|
GO:0002082 |
3 |
0.018
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.017
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.017
|
|
|
|
regulation of killing of cells of other organism
|
GO:0051709 |
4 |
0.017
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.017
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.017
|
|
|
|
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway
|
GO:1903378 |
2 |
0.017
|
|
|
|
response to alkaloid
|
GO:0043279 |
20 |
0.017
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.017
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.017
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.017
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.017
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.017
|
|
|
|
transformed cell apoptotic process
|
GO:0006927 |
3 |
0.017
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.017
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.017
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.017
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.017
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.016
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.016
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.016
|
|
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
16 |
0.016
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.016
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.016
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.016
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.016
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.016
|
|
|
|
apoptotic dna fragmentation
|
GO:0006309 |
6 |
0.016
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.016
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.016
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.016
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.016
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.016
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.016
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.016
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.015
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.015
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.015
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.015
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.015
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.015
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.015
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.015
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.015
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.015
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.015
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.015
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.015
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.015
|
Yeast |
|
|
protein alkylation
|
GO:0008213 |
74 |
0.015
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.015
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.015
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.015
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.014
|
|
