|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.986
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.948
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.941
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.867
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.782
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.751
|
Zebrafish |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.735
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.730
|
Yeast Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.728
|
Fly |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.682
|
Fly |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.659
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.657
|
Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.652
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.645
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.632
|
Worm |
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.605
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.597
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.573
|
|
|
|
regulation of nuclease activity
|
GO:0032069 |
11 |
0.558
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.549
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.498
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.470
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.467
|
Human |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.465
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.448
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.432
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.415
|
Fly |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.414
|
Human |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.412
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.411
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.393
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.388
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.388
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.387
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.382
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.382
|
Yeast Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.380
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.371
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.370
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.362
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.347
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.345
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.345
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.339
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.337
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.325
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.320
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.318
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.315
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.304
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.293
|
Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.288
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.281
|
Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.277
|
|
|
|
dna ligation involved in dna repair
|
GO:0051103 |
4 |
0.270
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.270
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.269
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.266
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.262
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.261
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.259
|
Yeast |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.248
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.245
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.238
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.238
|
|
|
|
v d j recombination
|
GO:0033151 |
3 |
0.234
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.230
|
Human Fly |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.225
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.222
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.221
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.210
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.207
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.205
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.203
|
Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.201
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.200
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.199
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.194
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.194
|
Yeast |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.191
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.191
|
|
|
|
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0017055 |
2 |
0.190
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.188
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.185
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.184
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.180
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.178
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.177
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.174
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.173
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.171
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.167
|
Yeast |
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.163
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.161
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.159
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.157
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.150
|
Worm |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.150
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.149
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.148
|
Worm |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.146
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.145
|
Human |
|
|
regulation of megakaryocyte differentiation
|
GO:0045652 |
22 |
0.144
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.141
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.139
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.134
|
|
|
|
negative regulation of dna templated transcription initiation
|
GO:2000143 |
3 |
0.133
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.133
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.130
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.129
|
|
|
|
growth
|
GO:0040007 |
202 |
0.129
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.127
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.126
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.126
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.126
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.126
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.123
|
Worm |
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.123
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.119
|
Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.117
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.114
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.113
|
Yeast Worm |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.112
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.112
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.110
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.110
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.108
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.105
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.103
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.103
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.099
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.097
|
Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.093
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.092
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.091
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.090
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.089
|
Zebrafish |
|
|
positive regulation of nuclease activity
|
GO:0032075 |
5 |
0.088
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.087
|
Worm |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.087
|
Fly |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.085
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.085
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.085
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.084
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.084
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.083
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.083
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.083
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.082
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.082
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
23 |
0.082
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.081
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.081
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.080
|
Fly |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.080
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.079
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.079
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.078
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.077
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.076
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.075
|
Yeast |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.075
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.073
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.073
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.073
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.072
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.072
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.072
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.070
|
Fly |
|
|
vesicle localization
|
GO:0051648 |
26 |
0.070
|
|
|
|
proteasomal ubiquitin independent protein catabolic process
|
GO:0010499 |
3 |
0.069
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.069
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.068
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.068
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.068
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.067
|
Human Yeast Worm |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.066
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.066
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.065
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.065
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.064
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.064
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.064
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.063
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.063
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.063
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.062
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.062
|
|
|
|
positive chemotaxis
|
GO:0050918 |
33 |
0.061
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.060
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.059
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.059
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.058
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.057
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.057
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.056
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.055
|
|
|
|
protein folding
|
GO:0006457 |
38 |
0.054
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.054
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.053
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.052
|
|
|
|
negative regulation of cellular response to oxidative stress
|
GO:1900408 |
18 |
0.052
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.052
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
3 |
0.052
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.052
|
Yeast |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.051
|
Worm |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.051
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.051
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.051
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.051
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.050
|
|
|
|
base excision repair dna ligation
|
GO:0006288 |
2 |
0.050
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.048
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.048
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.046
|
|
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.045
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.045
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.044
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.044
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.044
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.044
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.044
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.043
|
Yeast Worm |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.043
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.043
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.043
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.043
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.043
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.042
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.042
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.042
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.042
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.042
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.042
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.041
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.041
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.041
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.041
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.041
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.041
|
Yeast |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.040
|
|
|
|
er to golgi vesicle mediated transport
|
GO:0006888 |
19 |
0.040
|
Yeast |
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.040
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.040
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.040
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.040
|
Worm |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.039
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.039
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.039
|
Yeast Worm |
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.038
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.037
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.037
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.037
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.036
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.036
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.036
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.036
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.035
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.035
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.035
|
|
|
|
aging
|
GO:0007568 |
66 |
0.035
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.035
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.035
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.035
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.034
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.034
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.034
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.034
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.034
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.034
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.034
|
Fly |
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.034
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.034
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.034
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.033
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.032
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.032
|
Human Worm Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.032
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.032
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.032
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.032
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.032
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.032
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.032
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.031
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.031
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.031
|
Fly |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.031
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.031
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
38 |
0.030
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.030
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
4 |
0.030
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.030
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.030
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.029
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.029
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.029
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.029
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.029
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.029
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.029
|
Yeast |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.028
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.028
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.028
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.028
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.027
|
|
|
|
dna templated transcriptional preinitiation complex assembly
|
GO:0070897 |
5 |
0.027
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.027
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.027
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.027
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.026
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.026
|
Fly |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.026
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.026
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.026
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.025
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.025
|
Yeast |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.025
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.025
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.025
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.025
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.025
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.025
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.025
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.024
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.024
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.024
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.024
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.024
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.024
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.024
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.024
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.024
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.024
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.023
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.023
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.023
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.023
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.023
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.023
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.022
|
Human Yeast Worm |
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.022
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.022
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.022
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.022
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.022
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.021
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.021
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.021
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.021
|
|
|
|
axon extension
|
GO:0048675 |
13 |
0.021
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.021
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.021
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.021
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.021
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.021
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.021
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.020
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.020
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.020
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.020
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.020
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.020
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.020
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.020
|
|
|
|
regulation of hydrogen peroxide induced cell death
|
GO:1903205 |
10 |
0.019
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.019
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.019
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.019
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.019
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.019
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.019
|
|
|
|
neuron projection extension
|
GO:1990138 |
14 |
0.019
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.019
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.018
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.018
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.018
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.018
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.018
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.018
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.018
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.018
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.018
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.018
|
Worm |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
8 |
0.018
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.018
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.017
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.017
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.017
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.017
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.017
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.017
|
|
|
|
glucose homeostasis
|
GO:0042593 |
31 |
0.017
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.017
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.017
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.017
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.017
|
Fly |
|
|
cell growth
|
GO:0016049 |
160 |
0.017
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.017
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.017
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.016
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.016
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.016
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.016
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.016
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.016
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.016
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.016
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.016
|
Yeast |
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.016
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.016
|
|
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.016
|
|
|
|
response to monosaccharide
|
GO:0034284 |
20 |
0.016
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.016
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.016
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.016
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.016
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.016
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.016
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.016
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.016
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.015
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.015
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.015
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.015
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.015
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.015
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.015
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.015
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.015
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.015
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.015
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.015
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.015
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.014
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.014
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.014
|
Yeast |
|
|
neuron development
|
GO:0048666 |
113 |
0.014
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.014
|
|
|
|
cellular response to monosaccharide stimulus
|
GO:0071326 |
10 |
0.014
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.014
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.014
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.014
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.014
|
|
|
|
regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902041 |
24 |
0.014
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.014
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.014
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.014
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.014
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.014
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.014
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.013
|
Worm |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.013
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.013
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.013
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.013
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.013
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.013
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
18 |
0.013
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.013
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.013
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.013
|
Fly |
|
|
nuclear export
|
GO:0051168 |
69 |
0.013
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.013
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.013
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.013
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.013
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.013
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.013
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.013
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.013
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.012
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.012
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.012
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
17 |
0.012
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.012
|
|
|
|
regulation of hematopoietic progenitor cell differentiation
|
GO:1901532 |
24 |
0.012
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.012
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
31 |
0.012
|
|
|
|
protein destabilization
|
GO:0031648 |
12 |
0.012
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.012
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.012
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.012
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.012
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.012
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.012
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.012
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.012
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.012
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.012
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.012
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.012
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.012
|
|
