Homo sapiens

0 known processes

EIF4A2

eukaryotic translation initiation factor 4A2

(Aliases: DDX2B,eIF-4A-II,eIF4A-II,BM-010,EIF4F,EIF4A)

EIF4A2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translational initiation GO:0006413 48 0.670
Yeast
female gamete generation GO:0007292 2 0.208
Fly
organelle fission GO:0048285 149 0.145
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 0.124
Fly
determination of adult lifespan GO:0008340 2 0.121
Worm
translation GO:0006412 132 0.116
Yeast
memory GO:0007613 3 0.109
regulation of meiotic cell cycle GO:0051445 4 0.103
spermatid development GO:0007286 4 0.096
neuron differentiation GO:0030182 138 0.090
negative regulation of protein metabolic process GO:0051248 391 0.084
spermatid differentiation GO:0048515 4 0.083
rna splicing GO:0008380 131 0.081
Fly
positive regulation of cell differentiation GO:0045597 211 0.081
regulation of proteolysis GO:0030162 293 0.072
oocyte differentiation GO:0009994 2 0.071
post embryonic development GO:0009791 2 0.071
Worm
oocyte development GO:0048599 1 0.064
regulation of meiosis GO:0040020 3 0.063
oogenesis GO:0048477 2 0.062
Fly
single organism cellular localization GO:1902580 332 0.061
protein o linked glycosylation GO:0006493 21 0.060
nervous system development GO:0007399 293 0.058
regulation of nuclear division GO:0051783 65 0.057
positive regulation of organelle organization GO:0010638 195 0.056
autophagic cell death GO:0048102 3 0.056
response to abiotic stimulus GO:0009628 336 0.055
rna processing GO:0006396 255 0.054
Fly
regulation of translational initiation GO:0006446 24 0.052
locomotory behavior GO:0007626 1 0.050
posttranscriptional regulation of gene expression GO:0010608 213 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.048
regulation of rna splicing GO:0043484 62 0.047
Fly
positive regulation of phosphorylation GO:0042327 394 0.047
circadian behavior GO:0048512 2 0.046
protein modification by small protein conjugation GO:0032446 342 0.046
regulation of cell cycle process GO:0010564 266 0.046
atrioventricular valve development GO:0003171 3 0.045
glucosamine containing compound metabolic process GO:1901071 10 0.045
nuclear division GO:0000280 128 0.045
Fly
meiosis i GO:0007127 4 0.044
positive regulation of developmental process GO:0051094 314 0.043
system process GO:0003008 349 0.041
maintenance of location GO:0051235 112 0.041
Worm
regulation of growth GO:0040008 165 0.040
small gtpase mediated signal transduction GO:0007264 78 0.040
positive regulation of proteolysis GO:0045862 142 0.040
cell development GO:0048468 328 0.040
Fly
reactive oxygen species biosynthetic process GO:1903409 4 0.039
positive regulation of protein phosphorylation GO:0001934 313 0.038
apoptotic signaling pathway GO:0097190 268 0.038
cell projection organization GO:0030030 252 0.038
negative regulation of developmental process GO:0051093 247 0.037
Fly
cellular response to nitrogen compound GO:1901699 144 0.037
cytoplasmic translational initiation GO:0002183 6 0.036
mitochondrion distribution GO:0048311 3 0.036
cellular response to toxic substance GO:0097237 4 0.035
segmentation GO:0035282 4 0.035
mrna metabolic process GO:0016071 175 0.034
Fly
cell part morphogenesis GO:0032990 137 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.033
cellular macromolecule catabolic process GO:0044265 380 0.033
microtubule cytoskeleton organization GO:0000226 176 0.033
Fly
regulation of translation GO:0006417 89 0.033
mitochondrion organization GO:0007005 156 0.032
male gamete generation GO:0048232 22 0.032
protein homooligomerization GO:0051260 100 0.032
amino sugar metabolic process GO:0006040 15 0.032
chemical homeostasis GO:0048878 306 0.031
cilium assembly GO:0042384 63 0.031
generation of neurons GO:0048699 152 0.031
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.031
lipid localization GO:0010876 106 0.031
Worm
response to oxygen containing compound GO:1901700 369 0.031
dna conformation change GO:0071103 113 0.031
cardiovascular system development GO:0072358 262 0.031
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.030
protein maturation GO:0051604 233 0.030
sex differentiation GO:0007548 45 0.030
cellular ketone metabolic process GO:0042180 80 0.030
negative regulation of phosphorus metabolic process GO:0010563 267 0.030
secretion GO:0046903 254 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.028
reproductive process GO:0022414 106 0.028
Fly
secretion by cell GO:0032940 226 0.028
organelle assembly GO:0070925 176 0.027
cellular component morphogenesis GO:0032989 314 0.027
negative regulation of cellular amine metabolic process GO:0033239 3 0.027
neurogenesis GO:0022008 169 0.027
protein localization to membrane GO:0072657 160 0.027
circulatory system development GO:0072359 262 0.027
neuron development GO:0048666 113 0.026
regulation of endopeptidase activity GO:0052548 170 0.026
negative regulation of phosphorylation GO:0042326 174 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.025
spermatogenesis GO:0007283 22 0.025
cellular amine metabolic process GO:0044106 41 0.025
head development GO:0060322 108 0.025
carbohydrate metabolic process GO:0005975 207 0.025
anterior posterior axis specification GO:0009948 2 0.024
mitotic nuclear division GO:0007067 119 0.024
Fly
amine metabolic process GO:0009308 44 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
Fly
microtubule based process GO:0007017 210 0.024
Fly
mapk cascade GO:0000165 288 0.024
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
long term memory GO:0007616 2 0.023
cell projection morphogenesis GO:0048858 129 0.023
purine containing compound catabolic process GO:0072523 411 0.023
Yeast
sleep GO:0030431 2 0.023
protein catabolic process GO:0030163 325 0.023
chromatin organization GO:0006325 351 0.023
dephosphorylation GO:0016311 209 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
neurotransmitter secretion GO:0007269 4 0.022
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.022
positive regulation of meiotic cell cycle GO:0051446 2 0.022
cellular chemical homeostasis GO:0055082 180 0.021
cellular response to organonitrogen compound GO:0071417 124 0.021
negative regulation of protein modification process GO:0031400 200 0.021
regulation of neural precursor cell proliferation GO:2000177 4 0.021
ribonucleoprotein complex subunit organization GO:0071826 81 0.021
multi organism reproductive process GO:0044703 54 0.021
Fly
positive regulation of cell cycle GO:0045787 140 0.020
ras protein signal transduction GO:0007265 73 0.020
neuromuscular junction development GO:0007528 3 0.020
purine nucleotide catabolic process GO:0006195 405 0.020
Yeast
response to radiation GO:0009314 151 0.020
cellular protein catabolic process GO:0044257 261 0.020
membrane organization GO:0061024 292 0.020
multicellular organismal aging GO:0010259 3 0.020
Worm
regulation of cellular response to stress GO:0080135 244 0.020
protein ubiquitination GO:0016567 314 0.020
positive regulation of cell cycle process GO:0090068 106 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.019
regulation of mapk cascade GO:0043408 262 0.019
metal ion transport GO:0030001 272 0.019
single organism reproductive process GO:0044702 98 0.019
Fly
organophosphate catabolic process GO:0046434 430 0.019
Yeast
cell cell signaling GO:0007267 155 0.019
endomembrane system organization GO:0010256 196 0.019
central nervous system development GO:0007417 123 0.019
cellular carbohydrate metabolic process GO:0044262 84 0.019
behavioral response to ethanol GO:0048149 2 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
circadian sleep wake cycle process GO:0022410 2 0.019
developmental process involved in reproduction GO:0003006 66 0.018
Fly
glycoprotein biosynthetic process GO:0009101 91 0.018
glial cell migration GO:0008347 4 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
protein oligomerization GO:0051259 173 0.018
reactive oxygen species metabolic process GO:0072593 75 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.017
regulation of peptidase activity GO:0052547 180 0.017
regulation of protein processing GO:0070613 150 0.017
vesicle mediated transport GO:0016192 371 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
Yeast
modification dependent protein catabolic process GO:0019941 209 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
Yeast
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.017
Fly
cell morphogenesis GO:0000902 296 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
Yeast
peptidyl serine modification GO:0018209 106 0.017
sex determination GO:0007530 3 0.017
circadian sleep wake cycle GO:0042745 2 0.016
dna packaging GO:0006323 77 0.016
protein secretion GO:0009306 98 0.016
protein glycosylation GO:0006486 62 0.016
regulation of protein maturation GO:1903317 150 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
cellular amino acid metabolic process GO:0006520 116 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
dna repair GO:0006281 198 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
monosaccharide metabolic process GO:0005996 74 0.016
transmembrane transport GO:0055085 399 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.015
response to inorganic substance GO:0010035 127 0.015
mating GO:0007618 1 0.015
nucleotide catabolic process GO:0009166 408 0.015
Yeast
response to biotic stimulus GO:0009607 276 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
small molecule biosynthetic process GO:0044283 157 0.015
positive regulation of cell development GO:0010720 92 0.015
cellular ion homeostasis GO:0006873 168 0.015
positive regulation of catabolic process GO:0009896 310 0.015
stress activated mapk cascade GO:0051403 93 0.015
protein localization to organelle GO:0033365 280 0.015
macromolecule glycosylation GO:0043413 63 0.015
protein processing GO:0016485 226 0.015
mitotic cell cycle GO:0000278 326 0.015
Fly
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.015
cilium morphogenesis GO:0060271 75 0.015
rhythmic behavior GO:0007622 2 0.015
regulation of protein ubiquitination GO:0031396 95 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
brain development GO:0007420 97 0.015
response to hypoxia GO:0001666 96 0.015
intracellular mrna localization GO:0008298 1 0.015
regulation of carbohydrate metabolic process GO:0006109 54 0.015
carbohydrate derivative biosynthetic process GO:1901137 207 0.015
multicellular organismal reproductive process GO:0048609 40 0.014
Fly
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
Yeast
mrna processing GO:0006397 133 0.014
Fly
aging GO:0007568 66 0.014
Worm
cation transport GO:0006812 331 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
protein targeting GO:0006605 187 0.014
inner ear morphogenesis GO:0042472 4 0.014
response to organonitrogen compound GO:0010243 156 0.014
glycoprotein metabolic process GO:0009100 110 0.014
negative regulation of cell death GO:0060548 345 0.014
negative regulation of protein maturation GO:1903318 142 0.014
regulation of chromatin organization GO:1902275 56 0.014
behavior GO:0007610 112 0.014
golgi organization GO:0007030 38 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
multi organism cellular process GO:0044764 156 0.014
blastoderm segmentation GO:0007350 2 0.013
negative regulation of cell cycle GO:0045786 193 0.013
regulation of cell cycle GO:0051726 393 0.013
glycosylation GO:0070085 71 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
nucleoside phosphate catabolic process GO:1901292 412 0.013
Yeast
cell projection assembly GO:0030031 126 0.013
response to virus GO:0009615 126 0.013
response to other organism GO:0051707 261 0.013
muscle tissue development GO:0060537 62 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
intrinsic apoptotic signaling pathway GO:0097193 127 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
negative regulation of cellular catabolic process GO:0031330 83 0.013
protein targeting to membrane GO:0006612 42 0.013
regulation of protein catabolic process GO:0042176 155 0.013
neuron projection development GO:0031175 106 0.013
multicellular organism reproduction GO:0032504 42 0.013
Fly
regulation of stem cell differentiation GO:2000736 56 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
metencephalon development GO:0022037 2 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
reproduction GO:0000003 63 0.012
Worm Fly
heart development GO:0007507 95 0.012
response to bacterium GO:0009617 144 0.012
response to nitrogen compound GO:1901698 184 0.012
divalent inorganic cation transport GO:0072511 158 0.012
cell aging GO:0007569 52 0.012
negative regulation of protein processing GO:0010955 142 0.012
chromatin modification GO:0016568 298 0.012
muscle structure development GO:0061061 98 0.012
cilium organization GO:0044782 68 0.012
regulation of leukocyte differentiation GO:1902105 61 0.012
purine ribonucleoside catabolic process GO:0046130 398 0.012
Yeast
divalent metal ion transport GO:0070838 152 0.012
regulation of cell growth GO:0001558 135 0.012
cellular response to arsenic containing substance GO:0071243 4 0.011
wnt signaling pathway GO:0016055 156 0.011
somitogenesis GO:0001756 2 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
muscle cell differentiation GO:0042692 63 0.011
chromosome segregation GO:0007059 114 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
neuroblast proliferation GO:0007405 4 0.011
viral life cycle GO:0019058 132 0.011
detection of mechanical stimulus GO:0050982 4 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.011
nuclear transcribed mrna catabolic process GO:0000956 48 0.011
rna catabolic process GO:0006401 71 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
growth GO:0040007 202 0.011
mitotic cell cycle process GO:1903047 286 0.011
Fly
protein dephosphorylation GO:0006470 81 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
Yeast
regulation of transcription by chromatin organization GO:0034401 1 0.011
response to fungus GO:0009620 4 0.010
gamete generation GO:0007276 25 0.010
Fly
rna interference GO:0016246 4 0.010
ribonucleoside catabolic process GO:0042454 406 0.010
Yeast
regulation of response to external stimulus GO:0032101 222 0.010
sexual reproduction GO:0019953 37 0.010
Fly
ion homeostasis GO:0050801 230 0.010

EIF4A2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.048
nervous system disease DOID:863 431 0.048
neurodegenerative disease DOID:1289 102 0.038
musculoskeletal system disease DOID:17 223 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013