Homo sapiens

0 known processes

PAAF1

proteasomal ATPase-associated factor 1

(Aliases: WDR71,FLJ11848,PAAF,Rpn14)

PAAF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.154
multicellular organismal aging GO:0010259 3 0.135
nitrogen compound transport GO:0071705 191 0.074
determination of adult lifespan GO:0008340 2 0.072
dna templated transcription initiation GO:0006352 35 0.061
chemical homeostasis GO:0048878 306 0.058
ribonucleoside catabolic process GO:0042454 406 0.057
post embryonic development GO:0009791 2 0.055
nucleoside catabolic process GO:0009164 408 0.052
i kappab kinase nf kappab signaling GO:0007249 166 0.051
positive regulation of phosphorylation GO:0042327 394 0.049
nucleoside phosphate catabolic process GO:1901292 412 0.048
purine ribonucleotide catabolic process GO:0009154 404 0.048
regulation of protein complex assembly GO:0043254 147 0.046
secretion GO:0046903 254 0.046
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.045
glycosyl compound catabolic process GO:1901658 413 0.044
cellular amino acid metabolic process GO:0006520 116 0.044
purine nucleotide catabolic process GO:0006195 405 0.044
positive regulation of catabolic process GO:0009896 310 0.042
protein localization to organelle GO:0033365 280 0.040
ribonucleotide catabolic process GO:0009261 405 0.040
negative regulation of phosphate metabolic process GO:0045936 267 0.040
protein catabolic process GO:0030163 325 0.039
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 391 0.039
purine containing compound catabolic process GO:0072523 411 0.037
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
cellular amine metabolic process GO:0044106 41 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
protein dna complex subunit organization GO:0071824 80 0.036
ribonucleoside monophosphate metabolic process GO:0009161 187 0.036
maintenance of location GO:0051235 112 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.035
vesicle mediated transport GO:0016192 371 0.035
protein ubiquitination GO:0016567 314 0.035
amine metabolic process GO:0009308 44 0.035
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.035
regulation of cell cycle GO:0051726 393 0.035
purine ribonucleoside catabolic process GO:0046130 398 0.034
cellular macromolecule catabolic process GO:0044265 380 0.034
Yeast
protein modification by small protein conjugation GO:0032446 342 0.034
negative regulation of catalytic activity GO:0043086 335 0.034
positive regulation of cellular component organization GO:0051130 376 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.033
Yeast
regulation of kinase activity GO:0043549 314 0.033
cellular protein catabolic process GO:0044257 261 0.033
Yeast
regulation of protein localization GO:0032880 296 0.033
nervous system development GO:0007399 293 0.032
female gamete generation GO:0007292 2 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.032
negative regulation of phosphorylation GO:0042326 174 0.032
purine nucleoside catabolic process GO:0006152 398 0.032
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.032
nuclear transport GO:0051169 179 0.031
neurotransmitter secretion GO:0007269 4 0.031
blastocyst development GO:0001824 3 0.031
positive regulation of protein complex assembly GO:0031334 86 0.031
regulation of transferase activity GO:0051338 355 0.031
cellular protein complex assembly GO:0043623 188 0.030
Yeast
regulation of cellular amine metabolic process GO:0033238 11 0.030
purine nucleoside triphosphate metabolic process GO:0009144 412 0.030
regulation of protein serine threonine kinase activity GO:0071900 179 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.029
nucleotide catabolic process GO:0009166 408 0.029
nucleoside triphosphate metabolic process GO:0009141 422 0.029
cytoplasmic transport GO:0016482 379 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
mitochondrion organization GO:0007005 156 0.028
organelle assembly GO:0070925 176 0.028
negative regulation of transport GO:0051051 176 0.028
cellular ketone metabolic process GO:0042180 80 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.028
regulation of protein transport GO:0051223 213 0.028
regulation of cellular component biogenesis GO:0044087 281 0.027
regulation of response to dna damage stimulus GO:2001020 94 0.027
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.027
organophosphate catabolic process GO:0046434 430 0.027
mapk cascade GO:0000165 288 0.027
chromatin organization GO:0006325 351 0.027
locomotory behavior GO:0007626 1 0.027
positive regulation of protein phosphorylation GO:0001934 313 0.027
regulation of protein kinase activity GO:0045859 289 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
modification dependent protein catabolic process GO:0019941 209 0.026
Yeast
positive regulation of cellular catabolic process GO:0031331 284 0.026
mitotic cell cycle process GO:1903047 286 0.026
regulation of mapk cascade GO:0043408 262 0.026
regulation of proteolysis GO:0030162 293 0.026
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.026
nucleocytoplasmic transport GO:0006913 176 0.026
negative regulation of intracellular signal transduction GO:1902532 183 0.026
purine nucleoside monophosphate catabolic process GO:0009128 158 0.025
maintenance of protein location GO:0045185 57 0.025
protein localization to nucleus GO:0034504 136 0.025
secretion by cell GO:0032940 226 0.025
purine nucleoside triphosphate catabolic process GO:0009146 392 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
cellular macromolecular complex assembly GO:0034622 324 0.024
Yeast
regulation of apoptotic signaling pathway GO:2001233 175 0.024
microtubule cytoskeleton organization GO:0000226 176 0.024
segmentation GO:0035282 4 0.024
proteasomal protein catabolic process GO:0010498 176 0.024
microtubule based process GO:0007017 210 0.024
regulation of establishment of protein localization GO:0070201 242 0.023
positive regulation of cellular component biogenesis GO:0044089 158 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.022
positive regulation of protein catabolic process GO:0045732 75 0.022
intracellular protein transport GO:0006886 270 0.022
regulation of cell cycle process GO:0010564 266 0.022
ribonucleoside monophosphate catabolic process GO:0009158 158 0.022
regulation of peptidase activity GO:0052547 180 0.022
modification dependent macromolecule catabolic process GO:0043632 212 0.022
Yeast
positive regulation of cellular amine metabolic process GO:0033240 7 0.022
epithelium development GO:0060429 227 0.022
cellular component morphogenesis GO:0032989 314 0.022
regulation of protein catabolic process GO:0042176 155 0.022
chromatin modification GO:0016568 298 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
membrane organization GO:0061024 292 0.021
carbohydrate metabolic process GO:0005975 207 0.021
immune response GO:0006955 307 0.021
regulation of cytoplasmic transport GO:1903649 149 0.021
regulation of mitotic cell cycle GO:0007346 189 0.021
ncrna metabolic process GO:0034660 108 0.021
negative regulation of protein transport GO:0051224 75 0.021
response to oxygen containing compound GO:1901700 369 0.021
negative regulation of programmed cell death GO:0043069 321 0.020
regulation of cellular ketone metabolic process GO:0010565 50 0.020
regulation of cellular response to stress GO:0080135 244 0.020
nucleotide excision repair GO:0006289 31 0.020
regulation of cell growth GO:0001558 135 0.020
immune system development GO:0002520 195 0.020
response to disaccharide GO:0034285 1 0.020
defense response GO:0006952 315 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
cell division GO:0051301 168 0.020
oogenesis GO:0048477 2 0.019
regulation of proteasomal protein catabolic process GO:0061136 87 0.019
positive regulation of proteolysis GO:0045862 142 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
single organism cellular localization GO:1902580 332 0.019
small molecule biosynthetic process GO:0044283 157 0.019
hematopoietic or lymphoid organ development GO:0048534 186 0.019
cellular lipid metabolic process GO:0044255 303 0.019
regeneration GO:0031099 4 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
regulation of mitochondrion organization GO:0010821 54 0.019
regulation of intracellular transport GO:0032386 195 0.019
lipid biosynthetic process GO:0008610 177 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
negative regulation of cell death GO:0060548 345 0.019
system process GO:0003008 349 0.019
cell growth GO:0016049 160 0.018
atp catabolic process GO:0006200 157 0.018
mitotic cell cycle GO:0000278 326 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
spermatid differentiation GO:0048515 4 0.018
positive regulation of kinase activity GO:0033674 204 0.018
interspecies interaction between organisms GO:0044419 156 0.018
cell cycle phase transition GO:0044770 173 0.018
ubiquitin dependent protein catabolic process GO:0006511 206 0.018
Yeast
regulation of defense response GO:0031347 154 0.017
biological adhesion GO:0022610 331 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
spermatid development GO:0007286 4 0.017
apoptotic signaling pathway GO:0097190 268 0.017
growth GO:0040007 202 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
rho protein signal transduction GO:0007266 26 0.017
response to abiotic stimulus GO:0009628 336 0.017
hemopoiesis GO:0030097 180 0.017
cerebellum development GO:0021549 2 0.017
maintenance of location in cell GO:0051651 62 0.017
maintenance of protein location in cell GO:0032507 56 0.017
protein targeting GO:0006605 187 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
regulation of protein localization to nucleus GO:1900180 85 0.016
protein import GO:0017038 130 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.016
ras protein signal transduction GO:0007265 73 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
blastoderm segmentation GO:0007350 2 0.016
multi organism cellular process GO:0044764 156 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
protein secretion GO:0009306 98 0.016
serotonin transport GO:0006837 3 0.016
neuromuscular junction development GO:0007528 3 0.016
positive regulation of transferase activity GO:0051347 227 0.016
negative regulation of proteolysis GO:0045861 132 0.016
regulation of immune response GO:0050776 201 0.016
nuclear import GO:0051170 106 0.016
regulation of locomotion GO:0040012 329 0.015
lipid metabolic process GO:0006629 381 0.015
protein targeting to nucleus GO:0044744 104 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
proteasome regulatory particle assembly GO:0070682 2 0.015
Yeast
reactive oxygen species biosynthetic process GO:1903409 4 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
hindbrain development GO:0030902 3 0.015
dna repair GO:0006281 198 0.015
negative regulation of peptidase activity GO:0010466 91 0.015
viral process GO:0016032 146 0.015
negative regulation of apoptotic signaling pathway GO:2001234 97 0.015
innate immune response GO:0045087 178 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
response to salt stress GO:0009651 3 0.015
metencephalon development GO:0022037 2 0.015
regulation of cell differentiation GO:0045595 393 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
regulation of response to external stimulus GO:0032101 222 0.014
regulation of protein processing GO:0070613 150 0.014
single organism membrane organization GO:0044802 268 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.014
glycoprotein metabolic process GO:0009100 110 0.014
viral life cycle GO:0019058 132 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
negative regulation of protein processing GO:0010955 142 0.014
amide transport GO:0042886 76 0.014
organic acid biosynthetic process GO:0016053 97 0.014
covalent chromatin modification GO:0016569 254 0.014
actin filament based movement GO:0030048 17 0.014
negative regulation of organelle organization GO:0010639 126 0.014
negative regulation of protein modification process GO:0031400 200 0.014
regulation of cell division GO:0051302 116 0.014
regulation of protein import into nucleus GO:0042306 78 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
response to sucrose GO:0009744 1 0.013
regulation of dna metabolic process GO:0051052 153 0.013
spindle elongation GO:0051231 4 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
single organism nuclear import GO:1902593 104 0.013
regulation of peptide transport GO:0090087 62 0.013
myosin filament assembly GO:0031034 2 0.013
spindle organization GO:0007051 53 0.013
memory GO:0007613 3 0.013
organelle fission GO:0048285 149 0.013
negative regulation of immune system process GO:0002683 136 0.013
head development GO:0060322 108 0.013
oxidation reduction process GO:0055114 396 0.013
release of cytochrome c from mitochondria GO:0001836 35 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.013
protein maturation GO:0051604 233 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.013
double strand break repair GO:0006302 101 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.013
regulation of cell motility GO:2000145 299 0.013
negative regulation of intracellular transport GO:0032387 60 0.013
cation transport GO:0006812 331 0.012
transmembrane transport GO:0055085 399 0.012
protein dna complex assembly GO:0065004 64 0.012
regulation of protein targeting GO:1903533 91 0.012
positive regulation of cell cycle GO:0045787 140 0.012
ossification GO:0001503 121 0.012
striated muscle myosin thick filament assembly GO:0071688 2 0.012
positive regulation of endopeptidase activity GO:0010950 84 0.012
regulation of protein ubiquitination GO:0031396 95 0.012
protein import into nucleus GO:0006606 104 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
myeloid cell differentiation GO:0030099 117 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
receptor mediated endocytosis GO:0006898 84 0.012
negative regulation of protein localization to nucleus GO:1900181 34 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
leukocyte differentiation GO:0002521 98 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.012
regulation of multi organism process GO:0043900 157 0.012
cell adhesion GO:0007155 325 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of response to dna damage stimulus GO:2001021 33 0.012
regulation of transcription factor import into nucleus GO:0042990 39 0.012
protein deubiquitination GO:0016579 79 0.012
chromosome segregation GO:0007059 114 0.012
nerve development GO:0021675 4 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
endosomal transport GO:0016197 129 0.012
dephosphorylation GO:0016311 209 0.012
rna interference GO:0016246 4 0.011
negative regulation of cytoplasmic transport GO:1903650 46 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
blood vessel development GO:0001568 172 0.011
positive regulation of cell death GO:0010942 263 0.011
tissue regeneration GO:0042246 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
regulation of interleukin 8 secretion GO:2000482 13 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
regulation of cytokine production GO:0001817 232 0.011
epidermal cell differentiation GO:0009913 45 0.011
regulation of cellular component movement GO:0051270 334 0.011
cell projection organization GO:0030030 252 0.011
inner ear morphogenesis GO:0042472 4 0.011
chromosome separation GO:0051304 23 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
cell projection assembly GO:0030031 126 0.011
negative regulation of transferase activity GO:0051348 124 0.011
positive regulation of transport GO:0051050 336 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of secretion GO:0051046 194 0.011
rna processing GO:0006396 255 0.011
epithelial cell differentiation GO:0030855 141 0.011
myosin filament organization GO:0031033 2 0.011
icosanoid metabolic process GO:0006690 35 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
regulation of cell migration GO:0030334 289 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
negative regulation of intracellular protein transport GO:0090317 42 0.011
response to calcium ion GO:0051592 46 0.011
peripheral nervous system development GO:0007422 2 0.011
negative regulation of developmental process GO:0051093 247 0.011
salivary gland morphogenesis GO:0007435 4 0.011
response to organic cyclic compound GO:0014070 204 0.011
negative regulation of mapk cascade GO:0043409 56 0.011
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 0.011
meiosis i GO:0007127 4 0.011
nuclear division GO:0000280 128 0.011
mitotic sister chromatid separation GO:0051306 18 0.011
atp metabolic process GO:0046034 176 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
negative regulation of protein import into nucleus GO:0042308 30 0.011
cell substrate adhesion GO:0031589 132 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
cell development GO:0048468 328 0.011
sister chromatid segregation GO:0000819 54 0.011
reproductive process GO:0022414 106 0.011
cellular response to oxygen containing compound GO:1901701 276 0.010
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.010
response to nitrogen compound GO:1901698 184 0.010
lens development in camera type eye GO:0002088 2 0.010
dna conformation change GO:0071103 113 0.010
response to hormone GO:0009725 175 0.010
mitotic spindle elongation GO:0000022 4 0.010
signal transduction by phosphorylation GO:0023014 297 0.010
myeloid leukocyte differentiation GO:0002573 60 0.010
chromosome passenger complex localization to spindle midzone GO:0035853 1 0.010
rhythmic behavior GO:0007622 2 0.010
oocyte development GO:0048599 1 0.010
adult locomotory behavior GO:0008344 1 0.010
regulation of chromosome organization GO:0033044 103 0.010
monocarboxylic acid biosynthetic process GO:0072330 67 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
long chain fatty acid metabolic process GO:0001676 30 0.010
cardiovascular system development GO:0072358 262 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
neurogenesis GO:0022008 169 0.010
associative learning GO:0008306 1 0.010
cranial nerve development GO:0021545 4 0.010
cell morphogenesis GO:0000902 296 0.010
regulation of secretion by cell GO:1903530 177 0.010
aging GO:0007568 66 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
regulation of meiotic cell cycle GO:0051445 4 0.010
neutrophil clearance GO:0097350 1 0.010
dna geometric change GO:0032392 32 0.010
nucleotide biosynthetic process GO:0009165 109 0.010
wnt signaling pathway GO:0016055 156 0.010

PAAF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.051
inherited metabolic disorder DOID:655 242 0.051
musculoskeletal system disease DOID:17 223 0.030
immune system disease DOID:2914 155 0.021
sensory system disease DOID:0050155 203 0.020
nervous system disease DOID:863 431 0.020
cancer DOID:162 167 0.018
disease of cellular proliferation DOID:14566 174 0.018
connective tissue disease DOID:65 109 0.018
bone disease DOID:0080001 88 0.016
central nervous system disease DOID:331 186 0.015
organ system cancer DOID:0050686 164 0.014
amino acid metabolic disorder DOID:9252 50 0.012
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.010