Homo sapiens

7 known processes

NLRP8

NLR family, pyrin domain containing 8

(Aliases: CLR19.2,NALP8,NOD16,PAN4)

NLRP8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.314
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.065
post embryonic development GO:0009791 2 0.053
determination of adult lifespan GO:0008340 2 0.036
multicellular organismal aging GO:0010259 3 0.036
female gamete generation GO:0007292 2 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
negative regulation of protein metabolic process GO:0051248 391 0.032
Human
oogenesis GO:0048477 2 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.031
regulation of cellular amine metabolic process GO:0033238 11 0.031
detection of chemical stimulus GO:0009593 55 0.031
Human
cellular amine metabolic process GO:0044106 41 0.030
amine metabolic process GO:0009308 44 0.030
defense response GO:0006952 315 0.029
Human
cellular amino acid metabolic process GO:0006520 116 0.029
cellular ketone metabolic process GO:0042180 80 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
detection of stimulus GO:0051606 85 0.027
Human
system process GO:0003008 349 0.025
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
innate immune response GO:0045087 178 0.024
Human
sensory perception of smell GO:0007608 2 0.024
locomotory behavior GO:0007626 1 0.023
regeneration GO:0031099 4 0.023
detection of muramyl dipeptide GO:0032498 1 0.023
Human
immune response GO:0006955 307 0.022
Human
regulation of response to external stimulus GO:0032101 222 0.022
Human
cytoplasmic transport GO:0016482 379 0.022
Human
negative regulation of catalytic activity GO:0043086 335 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
Human
single organism cellular localization GO:1902580 332 0.021
Human
neuromuscular junction development GO:0007528 3 0.021
cellular response to endogenous stimulus GO:0071495 336 0.020
Human
signal transduction by phosphorylation GO:0023014 297 0.020
Human
negative regulation of phosphate metabolic process GO:0045936 267 0.020
Human
response to other organism GO:0051707 261 0.020
Human
segmentation GO:0035282 4 0.020
cellular macromolecule catabolic process GO:0044265 380 0.019
regulation of proteolysis GO:0030162 293 0.019
Human
response to oxygen containing compound GO:1901700 369 0.019
Human
positive regulation of transport GO:0051050 336 0.019
Human
chemical homeostasis GO:0048878 306 0.019
response to biotic stimulus GO:0009607 276 0.019
Human
regulation of cell cycle GO:0051726 393 0.019
mapk cascade GO:0000165 288 0.018
Human
actin mediated cell contraction GO:0070252 12 0.018
ion homeostasis GO:0050801 230 0.018
negative regulation of protein modification process GO:0031400 200 0.018
Human
protein localization to organelle GO:0033365 280 0.018
Human
regulation of transferase activity GO:0051338 355 0.018
regulation of peptidase activity GO:0052547 180 0.018
Human
negative regulation of programmed cell death GO:0043069 321 0.018
single organism membrane organization GO:0044802 268 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
Human
positive regulation of immune system process GO:0002684 283 0.017
Human
regulation of protein localization GO:0032880 296 0.017
Human
regulation of establishment of protein localization GO:0070201 242 0.017
Human
positive regulation of cell death GO:0010942 263 0.017
Human
spermatid differentiation GO:0048515 4 0.017
cellular lipid metabolic process GO:0044255 303 0.017
oocyte differentiation GO:0009994 2 0.017
positive regulation of proteolysis GO:0045862 142 0.017
Human
response to external biotic stimulus GO:0043207 261 0.017
Human
regulation of protein transport GO:0051223 213 0.017
Human
neurological system process GO:0050877 163 0.016
regulation of cell cycle process GO:0010564 266 0.016
mitotic cell cycle GO:0000278 326 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
Human
regulation of endopeptidase activity GO:0052548 170 0.016
Human
intracellular protein transport GO:0006886 270 0.016
Human
cellular protein catabolic process GO:0044257 261 0.016
regulation of intracellular transport GO:0032386 195 0.016
Human
regulation of cytokine production GO:0001817 232 0.016
Human
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
oocyte development GO:0048599 1 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
lipid metabolic process GO:0006629 381 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
Human
regulation of cellular component movement GO:0051270 334 0.015
cell morphogenesis GO:0000902 296 0.015
positive regulation of mhc class i biosynthetic process GO:0045345 4 0.015
Human
cardiac muscle cell contraction GO:0086003 4 0.015
protein maturation GO:0051604 233 0.015
protein catabolic process GO:0030163 325 0.015
actin filament based process GO:0030029 224 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
cellular component morphogenesis GO:0032989 314 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
regulation of immune response GO:0050776 201 0.015
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.015
Human
metal ion homeostasis GO:0055065 169 0.015
mitotic cell cycle process GO:1903047 286 0.015
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
regulation of cellular response to stress GO:0080135 244 0.015
Human
purine ribonucleoside metabolic process GO:0046128 437 0.015
protein processing GO:0016485 226 0.015
sensory perception GO:0007600 103 0.015
dephosphorylation GO:0016311 209 0.015
protein targeting GO:0006605 187 0.014
Human
spermatid development GO:0007286 4 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
Human
membrane organization GO:0061024 292 0.014
negative regulation of cellular amine metabolic process GO:0033239 3 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
transmembrane transport GO:0055085 399 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
protein ubiquitination GO:0016567 314 0.014
cell growth GO:0016049 160 0.014
apoptotic signaling pathway GO:0097190 268 0.014
blastoderm segmentation GO:0007350 2 0.014
anterior posterior axis specification GO:0009948 2 0.014
biological adhesion GO:0022610 331 0.014
regulation of mhc class i biosynthetic process GO:0045343 4 0.014
Human
posttranscriptional regulation of gene expression GO:0010608 213 0.014
negative regulation of cell death GO:0060548 345 0.014
circulatory system development GO:0072359 262 0.014
organelle assembly GO:0070925 176 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
Human
negative regulation of hydrolase activity GO:0051346 182 0.013
vesicle mediated transport GO:0016192 371 0.013
nitrogen compound transport GO:0071705 191 0.013
Human
negative regulation of protein phosphorylation GO:0001933 140 0.013
Human
negative regulation of transport GO:0051051 176 0.013
Human
cell division GO:0051301 168 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
Human
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
microtubule based process GO:0007017 210 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
response to abiotic stimulus GO:0009628 336 0.013
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.013
Human
meiosis i GO:0007127 4 0.013
actin filament based movement GO:0030048 17 0.013
circadian behavior GO:0048512 2 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.013
maintenance of location GO:0051235 112 0.013
Human
cellular chemical homeostasis GO:0055082 180 0.013
cytokine production GO:0001816 247 0.013
Human
negative regulation of developmental process GO:0051093 247 0.013
response to lipid GO:0033993 206 0.013
Human
rhythmic behavior GO:0007622 2 0.013
cell projection organization GO:0030030 252 0.013
regulation of protein kinase activity GO:0045859 289 0.013
organophosphate catabolic process GO:0046434 430 0.012
positive regulation of immune response GO:0050778 159 0.012
Human
ras protein signal transduction GO:0007265 73 0.012
defense response to other organism GO:0098542 129 0.012
Human
regulation of protein processing GO:0070613 150 0.012
hair follicle morphogenesis GO:0031069 2 0.012
cellular response to lipid GO:0071396 127 0.012
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.012
anatomical structure homeostasis GO:0060249 100 0.012
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
cell activation GO:0001775 213 0.012
Human
positive regulation of cellular catabolic process GO:0031331 284 0.012
cardiovascular system development GO:0072358 262 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
chromatin organization GO:0006325 351 0.012
angiogenesis GO:0001525 147 0.012
epidermis morphogenesis GO:0048730 3 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
cell adhesion GO:0007155 325 0.012
reactive oxygen species metabolic process GO:0072593 75 0.012
detection of peptidoglycan GO:0032499 1 0.012
Human
negative regulation of multicellular organismal process GO:0051241 317 0.012
Human
cation homeostasis GO:0055080 189 0.012
cellular homeostasis GO:0019725 196 0.012
associative learning GO:0008306 1 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
response to fungus GO:0009620 4 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
activation of immune response GO:0002253 114 0.012
Human
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
positive regulation of catabolic process GO:0009896 310 0.012
purine containing compound catabolic process GO:0072523 411 0.012
regulation of cell growth GO:0001558 135 0.012
negative regulation of cytokine production GO:0001818 82 0.012
Human
reactive nitrogen species metabolic process GO:2001057 3 0.012
rho protein signal transduction GO:0007266 26 0.012
nucleoside phosphate catabolic process GO:1901292 412 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.011
regulation of protein maturation GO:1903317 150 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
protein localization to membrane GO:0072657 160 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
endomembrane system organization GO:0010256 196 0.011
memory GO:0007613 3 0.011
regulation of mapk cascade GO:0043408 262 0.011
Human
regulation of growth GO:0040008 165 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
positive regulation of cytokine production GO:0001819 167 0.011
Human
nucleocytoplasmic transport GO:0006913 176 0.011
Human
secretion GO:0046903 254 0.011
Human
tissue regeneration GO:0042246 3 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
Human
response to bacterium GO:0009617 144 0.011
Human
regulation of cytoplasmic transport GO:1903649 149 0.011
Human
detection of stimulus involved in sensory perception GO:0050906 43 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
regulation of cell differentiation GO:0045595 393 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
small molecule biosynthetic process GO:0044283 157 0.011
regulation of kinase activity GO:0043549 314 0.011
compound eye development GO:0048749 1 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
lipid biosynthetic process GO:0008610 177 0.011
positive regulation of transferase activity GO:0051347 227 0.011
establishment of protein localization to organelle GO:0072594 172 0.011
Human
regulation of meiotic cell cycle GO:0051445 4 0.011
defense response to bacterium GO:0042742 63 0.011
Human
tissue homeostasis GO:0001894 63 0.011
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.011
cellular protein complex assembly GO:0043623 188 0.011
cell cycle phase transition GO:0044770 173 0.011
leukocyte activation GO:0045321 164 0.011
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
positive regulation of peptidase activity GO:0010952 88 0.011
Human
positive regulation of mapk cascade GO:0043410 190 0.011
Human
regulation of meiosis GO:0040020 3 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
nuclear transport GO:0051169 179 0.011
Human
nucleotide catabolic process GO:0009166 408 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
meiotic chromosome segregation GO:0045132 4 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
oxidation reduction process GO:0055114 396 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.010
Human
cellular response to hormone stimulus GO:0032870 125 0.010
purine nucleotide catabolic process GO:0006195 405 0.010
regulation of apoptotic signaling pathway GO:2001233 175 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.010
chromatin modification GO:0016568 298 0.010
purine nucleoside triphosphate catabolic process GO:0009146 392 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
fatty acid metabolic process GO:0006631 115 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
modification dependent protein catabolic process GO:0019941 209 0.010
vasculature development GO:0001944 181 0.010
wnt signaling pathway GO:0016055 156 0.010
purine ribonucleotide catabolic process GO:0009154 404 0.010
rna interference GO:0016246 4 0.010
regulation of cell motility GO:2000145 299 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
visual behavior GO:0007632 2 0.010
negative regulation of protein maturation GO:1903318 142 0.010
cardiac muscle contraction GO:0060048 34 0.010
positive regulation of organelle organization GO:0010638 195 0.010
interspecies interaction between organisms GO:0044419 156 0.010
ribonucleoside catabolic process GO:0042454 406 0.010
negative regulation of proteolysis GO:0045861 132 0.010
regulation of cell adhesion GO:0030155 166 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
Human
regulation of locomotion GO:0040012 329 0.010
positive regulation of developmental process GO:0051094 314 0.010

NLRP8 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
disease of metabolism DOID:0014667 295 0.017
immune system disease DOID:2914 155 0.016
Human
musculoskeletal system disease DOID:17 223 0.015
retinal disease DOID:5679 118 0.013
retinal degeneration DOID:8466 89 0.012
inherited metabolic disorder DOID:655 242 0.012
cancer DOID:162 167 0.011
Human
disease of cellular proliferation DOID:14566 174 0.011
Human
bone disease DOID:0080001 88 0.011
connective tissue disease DOID:65 109 0.011
organ system cancer DOID:0050686 164 0.011