|
|
response to nitrosative stress
|
GO:0051409 |
4 |
0.507
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.416
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.367
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.350
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.271
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.263
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.259
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.239
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.232
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.226
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.217
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.213
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.208
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.205
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.202
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.200
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.187
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.184
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.179
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.173
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.171
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.170
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.167
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.163
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.163
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.158
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.157
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.154
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.153
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.150
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.145
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.142
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.139
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.138
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.134
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.132
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.130
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.124
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.121
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
14 |
0.118
|
|
|
|
inactivation of mapk activity
|
GO:0000188 |
5 |
0.118
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.117
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.117
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.116
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.115
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.115
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.114
|
Fly |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.112
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.112
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.111
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.111
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.108
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.107
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.106
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.105
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.103
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.102
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.102
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.101
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.101
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.099
|
|
|
|
system process
|
GO:0003008 |
349 |
0.099
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.098
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.098
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.096
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.096
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.094
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.094
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.093
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.090
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.090
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.089
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.088
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.086
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.085
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.085
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.083
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.083
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.083
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.081
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.080
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.079
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.078
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.077
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.077
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.076
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.076
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.073
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.073
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.072
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.071
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.070
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.068
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.067
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.066
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.066
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.065
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.065
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.065
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.064
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.061
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.060
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.059
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.059
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.059
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.058
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.058
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.058
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.058
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.057
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.057
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.056
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.056
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.056
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.055
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.055
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.055
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.054
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.054
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.054
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.054
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.053
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.052
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.052
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.051
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.051
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.050
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.050
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.050
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.050
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.049
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.049
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.049
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.048
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.048
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.047
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.046
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.046
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.046
|
Human |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.045
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.045
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.045
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.044
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.043
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.043
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.042
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.042
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.042
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.041
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.041
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.041
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.041
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.041
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.041
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.040
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.040
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.040
|
|
|
|
translation
|
GO:0006412 |
132 |
0.039
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.038
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.037
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.037
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.037
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.037
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.037
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.036
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.036
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.036
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.036
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.036
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.036
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.036
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.035
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.035
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.035
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.035
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.035
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.034
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.033
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.033
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.033
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.033
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.033
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.033
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.032
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.032
|
|
|
|
defense response to fungus
|
GO:0050832 |
4 |
0.032
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.032
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.032
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.032
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.031
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.031
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.031
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.031
|
|
|
|
growth
|
GO:0040007 |
202 |
0.031
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.031
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.030
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.030
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.030
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.030
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.030
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.030
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.030
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.030
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.030
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.030
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.030
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.030
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.029
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.029
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.029
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.029
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.029
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.029
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.029
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.029
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.029
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.029
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.029
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.029
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.028
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.028
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.028
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.028
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.027
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.027
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.027
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.027
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.027
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.026
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.026
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.026
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.026
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.026
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.026
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.026
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.026
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.025
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.025
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.025
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.025
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.025
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.025
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.025
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.025
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.025
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.024
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.024
|
|
|
|
p38mapk cascade
|
GO:0038066 |
9 |
0.024
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.024
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.024
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.024
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.024
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.023
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.023
|
Human |
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.023
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.023
|
|
|
|
mechanosensory behavior
|
GO:0007638 |
4 |
0.023
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.023
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.023
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.023
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.023
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.022
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
11 |
0.022
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.022
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.022
|
Human |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.022
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.022
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.022
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.022
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.021
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.021
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.021
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.021
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.021
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.021
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.021
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.020
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.020
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.020
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.020
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.020
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.020
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.020
|
|
|
|
immune response in mucosal associated lymphoid tissue
|
GO:0002386 |
1 |
0.020
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.020
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.020
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.020
|
|
|
|
negative regulation of eosinophil activation
|
GO:1902567 |
1 |
0.020
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.020
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.020
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.020
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.019
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.019
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.019
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.019
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.019
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.019
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.019
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.019
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.019
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.019
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.019
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.018
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.018
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.018
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.018
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.018
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.018
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.018
|
|
|
|
memory
|
GO:0007613 |
3 |
0.018
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.018
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.018
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.018
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.018
|
|
|
|
head development
|
GO:0060322 |
108 |
0.018
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.018
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.018
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.018
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.017
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.017
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.017
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.017
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.017
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.017
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.017
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.017
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.017
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.017
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.017
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.017
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.017
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.017
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.017
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.017
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.017
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.017
|
|
|
|
mucosal immune response
|
GO:0002385 |
21 |
0.017
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.016
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.016
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.016
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.016
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.016
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.016
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.016
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.016
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.016
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.016
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.016
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.016
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.016
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.016
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.016
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.015
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.015
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.015
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.015
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.015
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.015
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.015
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.015
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.015
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.015
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.015
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.015
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.015
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.015
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.015
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.015
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.015
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.015
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.015
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.014
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.014
|
Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.014
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.014
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.014
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.014
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.014
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.014
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.014
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.014
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.014
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.014
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.014
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.014
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.014
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.014
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.014
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.014
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.014
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.014
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.014
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.014
|
Human |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.013
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.013
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.013
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.013
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.013
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.013
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.013
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.013
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.013
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.013
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.013
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.013
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.013
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.013
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.013
|
|
|
|
translational initiation
|
GO:0006413 |
48 |
0.013
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.013
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.013
|
|
|
|
regulation of eosinophil activation
|
GO:1902566 |
2 |
0.013
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.013
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.013
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.013
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.013
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.013
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.013
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.013
|
Human |
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
0.013
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.013
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.013
|
|
|
|
sensory perception of smell
|
GO:0007608 |
2 |
0.013
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.012
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.012
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.012
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.012
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.012
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.012
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.012
|
|
|
|
negative regulation of mast cell activation involved in immune response
|
GO:0033007 |
1 |
0.012
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.012
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.012
|
|
|
|
negative regulation of actin nucleation
|
GO:0051126 |
3 |
0.012
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.012
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.012
|
|
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.012
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.012
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.012
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.012
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.012
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.012
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.012
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.012
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.012
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.012
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.012
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
41 |
0.012
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.012
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.012
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.012
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.011
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.011
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.011
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.011
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.011
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.011
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.011
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.011
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.011
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.011
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.011
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.011
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.011
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.011
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.011
|
|
|
|
detection of chemical stimulus involved in sensory perception
|
GO:0050907 |
33 |
0.011
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.011
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.011
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.011
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.011
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.011
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.011
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.011
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.011
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.011
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.011
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.011
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.011
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.011
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.011
|
|
