Homo sapiens

210 known processes

ERCC3

excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

(Aliases: TFIIH,GTF2H,RAD25,BTF2,XPB)

ERCC3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide excision repair GO:0006289 31 0.994
phosphorylation of rna polymerase ii c terminal domain GO:0070816 3 0.988
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 158 0.947
purine nucleoside triphosphate metabolic process GO:0009144 412 0.907
purine ribonucleotide catabolic process GO:0009154 404 0.904
purine nucleoside monophosphate catabolic process GO:0009128 158 0.886
nucleoside catabolic process GO:0009164 408 0.875
nucleoside phosphate catabolic process GO:1901292 412 0.867
purine nucleotide catabolic process GO:0006195 405 0.856
ribonucleotide catabolic process GO:0009261 405 0.847
purine nucleoside triphosphate catabolic process GO:0009146 392 0.832
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.827
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.824
dna repair GO:0006281 198 0.815
atp catabolic process GO:0006200 157 0.814
glycosyl compound catabolic process GO:1901658 413 0.814
ribonucleoside catabolic process GO:0042454 406 0.797
atp metabolic process GO:0046034 176 0.773
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.770
nucleoside monophosphate catabolic process GO:0009125 159 0.728
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.712
purine nucleoside monophosphate metabolic process GO:0009126 186 0.703
nucleoside triphosphate metabolic process GO:0009141 422 0.700
nucleotide catabolic process GO:0009166 408 0.699
ribonucleoside monophosphate metabolic process GO:0009161 187 0.694
ribonucleoside triphosphate metabolic process GO:0009199 412 0.644
purine nucleoside catabolic process GO:0006152 398 0.621
nucleoside triphosphate catabolic process GO:0009143 394 0.619
purine ribonucleoside metabolic process GO:0046128 437 0.588
nucleoside monophosphate metabolic process GO:0009123 191 0.533
regulation of cell cycle GO:0051726 393 0.494
purine containing compound catabolic process GO:0072523 411 0.494
purine ribonucleoside catabolic process GO:0046130 398 0.477
organophosphate catabolic process GO:0046434 430 0.444
cellular response to dna damage stimulus GO:0006974 379 0.431
ribonucleoside triphosphate catabolic process GO:0009203 391 0.398
regulation of mitotic cell cycle phase transition GO:1901990 118 0.221
mitotic cell cycle GO:0000278 326 0.175
mitotic cell cycle process GO:1903047 286 0.167
mrna metabolic process GO:0016071 175 0.142
Fly
negative regulation of cell cycle phase transition GO:1901988 89 0.127
multicellular organismal aging GO:0010259 3 0.121
regulation of mitotic cell cycle GO:0007346 189 0.113
mitotic cell cycle phase transition GO:0044772 162 0.105
ribonucleoprotein complex biogenesis GO:0022613 116 0.103
ribonucleoprotein complex assembly GO:0022618 78 0.093
regulation of meiotic cell cycle GO:0051445 4 0.090
negative regulation of cell cycle process GO:0010948 121 0.088
cell cycle phase transition GO:0044770 173 0.087
regulation of cell cycle process GO:0010564 266 0.087
oogenesis GO:0048477 2 0.085
vesicle mediated transport GO:0016192 371 0.081
cell cycle checkpoint GO:0000075 117 0.073
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.071
cellular macromolecular complex assembly GO:0034622 324 0.070
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.069
post embryonic development GO:0009791 2 0.066
dna damage checkpoint GO:0000077 68 0.061
determination of adult lifespan GO:0008340 2 0.060
regulation of protein kinase activity GO:0045859 289 0.057
endocytosis GO:0006897 159 0.056
regulation of purine nucleotide metabolic process GO:1900542 264 0.055
regulation of kinase activity GO:0043549 314 0.052
chromatin organization GO:0006325 351 0.048
positive regulation of cellular component organization GO:0051130 376 0.046
female gamete generation GO:0007292 2 0.046
single organism reproductive process GO:0044702 98 0.046
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.042
Yeast
cellular amine metabolic process GO:0044106 41 0.042
mrna processing GO:0006397 133 0.041
Fly
negative regulation of cell cycle GO:0045786 193 0.040
nervous system development GO:0007399 293 0.040
dna integrity checkpoint GO:0031570 71 0.038
ribonucleoprotein complex subunit organization GO:0071826 81 0.037
positive regulation of protein complex assembly GO:0031334 86 0.035
amine metabolic process GO:0009308 44 0.033
negative regulation of mitotic cell cycle GO:0045930 102 0.033
positive regulation of hydrolase activity GO:0051345 331 0.033
regulation of protein serine threonine kinase activity GO:0071900 179 0.032
regulation of nucleotide metabolic process GO:0006140 269 0.031
positive regulation of cellular component biogenesis GO:0044089 158 0.030
receptor mediated endocytosis GO:0006898 84 0.030
cell division GO:0051301 168 0.029
ras protein signal transduction GO:0007265 73 0.028
cellular protein complex assembly GO:0043623 188 0.028
rna interference GO:0016246 4 0.028
regulation of transferase activity GO:0051338 355 0.028
negative regulation of phosphorus metabolic process GO:0010563 267 0.028
regulation of meiosis GO:0040020 3 0.028
cellular ketone metabolic process GO:0042180 80 0.027
regulation of sister chromatid segregation GO:0033045 27 0.027
response to abiotic stimulus GO:0009628 336 0.027
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.026
cellular amino acid metabolic process GO:0006520 116 0.025
peptidyl lysine modification GO:0018205 144 0.025
positive regulation of cell death GO:0010942 263 0.025
positive regulation of nucleotide metabolic process GO:0045981 230 0.025
reproductive system development GO:0061458 56 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
nuclear division GO:0000280 128 0.024
mitotic cell cycle checkpoint GO:0007093 68 0.024
internal peptidyl lysine acetylation GO:0018393 97 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
protein acylation GO:0043543 138 0.024
negative regulation of phosphate metabolic process GO:0045936 267 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
regulation of nucleotide catabolic process GO:0030811 205 0.023
locomotory behavior GO:0007626 1 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
embryo development GO:0009790 123 0.022
Worm
posttranscriptional regulation of gene expression GO:0010608 213 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
regulation of purine nucleotide catabolic process GO:0033121 205 0.021
adult locomotory behavior GO:0008344 1 0.021
regulation of gtpase activity GO:0043087 180 0.020
rna processing GO:0006396 255 0.020
Fly
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.020
striated muscle contraction GO:0006941 52 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
negative regulation of cellular protein metabolic process GO:0032269 353 0.020
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.020
regulation of cell division GO:0051302 116 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
neurogenesis GO:0022008 169 0.019
reproduction GO:0000003 63 0.019
cell morphogenesis GO:0000902 296 0.019
cytoplasmic transport GO:0016482 379 0.019
Yeast
guanosine containing compound catabolic process GO:1901069 239 0.018
regulation of defense response GO:0031347 154 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
carbohydrate derivative biosynthetic process GO:1901137 207 0.018
protein dephosphorylation GO:0006470 81 0.018
positive regulation of catabolic process GO:0009896 310 0.018
cellular macromolecule catabolic process GO:0044265 380 0.018
meiosis i GO:0007127 4 0.017
dephosphorylation GO:0016311 209 0.017
guanosine containing compound metabolic process GO:1901068 244 0.017
regulation of cellular component movement GO:0051270 334 0.017
gtp metabolic process GO:0046039 239 0.017
intracellular protein transport GO:0006886 270 0.016
cellular response to organic cyclic compound GO:0071407 127 0.016
response to inorganic substance GO:0010035 127 0.016
circulatory system development GO:0072359 262 0.016
negative regulation of cell differentiation GO:0045596 171 0.016
central nervous system development GO:0007417 123 0.016
ubiquitin dependent protein catabolic process GO:0006511 206 0.016
internal protein amino acid acetylation GO:0006475 101 0.016
regulation of chromosome organization GO:0033044 103 0.016
regulation of ras protein signal transduction GO:0046578 155 0.015
transmembrane transport GO:0055085 399 0.015
regulation of microtubule based process GO:0032886 74 0.015
regulation of gtp catabolic process GO:0033124 180 0.015
regulation of cytokine production GO:0001817 232 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
mapk cascade GO:0000165 288 0.015
defense response GO:0006952 315 0.015
chromosome segregation GO:0007059 114 0.014
reproductive process GO:0022414 106 0.014
gtp catabolic process GO:0006184 237 0.014
rna splicing via transesterification reactions GO:0000375 90 0.014
Fly
reproductive structure development GO:0048608 55 0.014
regulation of dna metabolic process GO:0051052 153 0.014
Yeast
apoptotic signaling pathway GO:0097190 268 0.014
regulation of viral process GO:0050792 103 0.013
regulation of small gtpase mediated signal transduction GO:0051056 156 0.013
rna splicing GO:0008380 131 0.013
Fly
cardiovascular system development GO:0072358 262 0.013
cerebellum development GO:0021549 2 0.013
defense response to other organism GO:0098542 129 0.013
response to metal ion GO:0010038 84 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
receptor metabolic process GO:0043112 81 0.013
ncrna metabolic process GO:0034660 108 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
protein dna complex assembly GO:0065004 64 0.013
mitotic dna integrity checkpoint GO:0044774 30 0.013
cellular component morphogenesis GO:0032989 314 0.013
protein localization to organelle GO:0033365 280 0.013
negative regulation of protein metabolic process GO:0051248 391 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
response to radiation GO:0009314 151 0.012
response to uv GO:0009411 73 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
positive regulation of dna templated transcription elongation GO:0032786 18 0.012
response to uv b GO:0010224 10 0.012
rho protein signal transduction GO:0007266 26 0.012
positive regulation of transport GO:0051050 336 0.012
7 methylguanosine mrna capping GO:0006370 7 0.012
carbohydrate metabolic process GO:0005975 207 0.012
thymus development GO:0048538 3 0.012
single organism membrane organization GO:0044802 268 0.012
response to oxygen containing compound GO:1901700 369 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
nucleotide excision repair dna incision GO:0033683 7 0.011
covalent chromatin modification GO:0016569 254 0.011
endomembrane system organization GO:0010256 196 0.011
chromatin modification GO:0016568 298 0.011
response to light stimulus GO:0009416 87 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
response to nitrogen compound GO:1901698 184 0.011
mitochondrion organization GO:0007005 156 0.011
protein acetylation GO:0006473 116 0.011
biological adhesion GO:0022610 331 0.011
regulation of protein complex assembly GO:0043254 147 0.011
histone acetylation GO:0016573 93 0.011
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.011
negative regulation of cellular component movement GO:0051271 106 0.011
microtubule based process GO:0007017 210 0.011
transcription from rna polymerase i promoter GO:0006360 11 0.011
maintenance of location GO:0051235 112 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
Fly
cytokine production GO:0001816 247 0.011
mrna splicing via spliceosome GO:0000398 89 0.011
Fly
response to hormone GO:0009725 175 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
immune system development GO:0002520 195 0.011
cellular lipid metabolic process GO:0044255 303 0.011
regulation of cell motility GO:2000145 299 0.011
response to wounding GO:0009611 168 0.011
organelle fission GO:0048285 149 0.011
growth GO:0040007 202 0.011
regulation of protein localization GO:0032880 296 0.010
blood vessel development GO:0001568 172 0.010
negative regulation of protein modification process GO:0031400 200 0.010
response to bacterium GO:0009617 144 0.010
segmentation GO:0035282 4 0.010
tripartite regional subdivision GO:0007351 2 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
gene silencing by mirna GO:0035195 23 0.010
regulation of mapk cascade GO:0043408 262 0.010
regulation of response to external stimulus GO:0032101 222 0.010
negative regulation of locomotion GO:0040013 118 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
nitrogen compound transport GO:0071705 191 0.010
Yeast

ERCC3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.040
nervous system disease DOID:863 431 0.040
neurodegenerative disease DOID:1289 102 0.028
sensory system disease DOID:0050155 203 0.025
eye and adnexa disease DOID:1492 150 0.023
eye disease DOID:5614 149 0.023
xeroderma pigmentosum DOID:0050427 8 0.019
retinal disease DOID:5679 118 0.018
cancer DOID:162 167 0.016
disease of cellular proliferation DOID:14566 174 0.016
retinal degeneration DOID:8466 89 0.015
disease of mental health DOID:150 70 0.013
muscular disease DOID:0080000 114 0.011
musculoskeletal system disease DOID:17 223 0.011
photosensitive trichothiodystrophy DOID:2960 3 0.000