Homo sapiens

80 known processes

UNC119

unc-119 homolog (C. elegans)

(Aliases: POC7,HRG4,POC7A)

UNC119 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intraciliary transport GO:0042073 7 0.915
ribonucleoside triphosphate catabolic process GO:0009203 391 0.914
gtp catabolic process GO:0006184 237 0.856
purine ribonucleotide catabolic process GO:0009154 404 0.850
purine containing compound catabolic process GO:0072523 411 0.813
positive regulation of protein polymerization GO:0032273 45 0.741
guanosine containing compound metabolic process GO:1901068 244 0.735
nucleoside triphosphate catabolic process GO:0009143 394 0.728
regulation of purine nucleotide catabolic process GO:0033121 205 0.704
purine nucleoside triphosphate catabolic process GO:0009146 392 0.699
glycosyl compound catabolic process GO:1901658 413 0.694
organophosphate catabolic process GO:0046434 430 0.670
purine nucleoside catabolic process GO:0006152 398 0.652
regulation of nucleotide catabolic process GO:0030811 205 0.630
regulation of nucleoside metabolic process GO:0009118 209 0.571
gtp metabolic process GO:0046039 239 0.568
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.565
regulation of gtpase activity GO:0043087 180 0.547
photoreceptor cell differentiation GO:0046530 2 0.528
regulation of nucleotide metabolic process GO:0006140 269 0.524
nucleotide catabolic process GO:0009166 408 0.519
purine ribonucleoside catabolic process GO:0046130 398 0.507
regulation of gtp catabolic process GO:0033124 180 0.504
purine nucleotide catabolic process GO:0006195 405 0.498
nucleoside phosphate catabolic process GO:1901292 412 0.437
guanosine containing compound catabolic process GO:1901069 239 0.435
positive regulation of nucleotide catabolic process GO:0030813 185 0.416
cellular component morphogenesis GO:0032989 314 0.402
nucleoside triphosphate metabolic process GO:0009141 422 0.394
nucleoside catabolic process GO:0009164 408 0.393
positive regulation of cellular component organization GO:0051130 376 0.391
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.385
ribonucleoside triphosphate metabolic process GO:0009199 412 0.377
protein polymerization GO:0051258 71 0.366
regulation of protein polymerization GO:0032271 63 0.359
post embryonic development GO:0009791 2 0.359
female gamete generation GO:0007292 2 0.346
purine nucleoside triphosphate metabolic process GO:0009144 412 0.331
regulation of purine nucleotide metabolic process GO:1900542 264 0.314
ribonucleotide catabolic process GO:0009261 405 0.310
pyrimidine containing compound catabolic process GO:0072529 13 0.302
ribonucleoside catabolic process GO:0042454 406 0.295
cellular macromolecular complex assembly GO:0034622 324 0.280
cell development GO:0048468 328 0.263
actin filament organization GO:0007015 128 0.249
kidney development GO:0001822 53 0.244
small gtpase mediated signal transduction GO:0007264 78 0.242
oogenesis GO:0048477 2 0.226
nervous system development GO:0007399 293 0.220
positive regulation of cytoskeleton organization GO:0051495 83 0.199
cellular response to endogenous stimulus GO:0071495 336 0.172
cation transport GO:0006812 331 0.170
urogenital system development GO:0001655 65 0.167
positive regulation of gtp catabolic process GO:0033126 166 0.161
positive regulation of actin filament polymerization GO:0030838 38 0.158
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.156
positive regulation of organelle organization GO:0010638 195 0.150
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.149
response to radiation GO:0009314 151 0.146
regulation of rho protein signal transduction GO:0035023 79 0.139
peptidyl threonine phosphorylation GO:0018107 41 0.138
positive regulation of catabolic process GO:0009896 310 0.134
central nervous system development GO:0007417 123 0.120
actin cytoskeleton organization GO:0030036 207 0.110
cell morphogenesis GO:0000902 296 0.108
cellular response to growth factor stimulus GO:0071363 197 0.103
regulation of cellular component size GO:0032535 82 0.101
amine metabolic process GO:0009308 44 0.100
negative regulation of cellular component movement GO:0051271 106 0.095
cytoskeleton dependent intracellular transport GO:0030705 21 0.095
purine ribonucleoside metabolic process GO:0046128 437 0.094
neuromuscular junction development GO:0007528 3 0.094
oocyte differentiation GO:0009994 2 0.093
regulation of cellular component biogenesis GO:0044087 281 0.093
vesicle organization GO:0016050 62 0.089
neuron development GO:0048666 113 0.089
positive regulation of protein complex assembly GO:0031334 86 0.088
positive regulation of cellular component biogenesis GO:0044089 158 0.087
negative regulation of programmed cell death GO:0043069 321 0.086
negative regulation of apoptotic process GO:0043066 316 0.085
epithelium development GO:0060429 227 0.084
regulation of axon guidance GO:1902667 3 0.084
cell part morphogenesis GO:0032990 137 0.080
regulation of cell projection organization GO:0031344 107 0.080
cell projection organization GO:0030030 252 0.079
chromatin organization GO:0006325 351 0.079
metencephalon development GO:0022037 2 0.076
neurogenesis GO:0022008 169 0.074
positive regulation of nucleotide metabolic process GO:0045981 230 0.072
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.072
positive regulation of cellular catabolic process GO:0031331 284 0.071
rho protein signal transduction GO:0007266 26 0.069
cellular amino acid metabolic process GO:0006520 116 0.066
nucleobase catabolic process GO:0046113 4 0.066
negative regulation of nucleotide catabolic process GO:0030812 16 0.065
regulation of anatomical structure morphogenesis GO:0022603 286 0.064
positive regulation of nucleoside metabolic process GO:0045979 186 0.063
regulation of cell morphogenesis GO:0022604 153 0.062
axonogenesis GO:0007409 31 0.062
vesicle mediated transport GO:0016192 371 0.062
Mouse
negative regulation of smoothened signaling pathway GO:0045879 3 0.059
regulation of cellular amine metabolic process GO:0033238 11 0.058
histone modification GO:0016570 251 0.058
taxis GO:0042330 157 0.055
renal system development GO:0072001 63 0.054
peptidyl serine modification GO:0018209 106 0.053
negative regulation of cell proliferation GO:0008285 228 0.053
neural tube formation GO:0001841 3 0.053
secretion by cell GO:0032940 226 0.052
regulation of chemotaxis GO:0050920 74 0.051
regulation of actin filament based process GO:0032970 141 0.050
positive regulation of hydrolase activity GO:0051345 331 0.050
negative regulation of phosphate metabolic process GO:0045936 267 0.049
establishment of nucleus localization GO:0040023 1 0.049
chemotaxis GO:0006935 157 0.049
negative regulation of hydrolase activity GO:0051346 182 0.049
cerebellum development GO:0021549 2 0.049
cellular protein complex assembly GO:0043623 188 0.048
negative regulation of hepatocyte growth factor receptor signaling pathway GO:1902203 1 0.048
organ morphogenesis GO:0009887 147 0.048
actin filament polymerization GO:0030041 45 0.047
regulation of axon extension involved in axon guidance GO:0048841 2 0.047
regulation of transferase activity GO:0051338 355 0.047
regulation of protein complex assembly GO:0043254 147 0.047
developmental cell growth GO:0048588 18 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
microtubule polymerization GO:0046785 18 0.044
phototransduction GO:0007602 3 0.043
negative regulation of nucleotide metabolic process GO:0045980 29 0.043
axon cargo transport GO:0008088 2 0.042
neuron differentiation GO:0030182 138 0.042
spinal cord development GO:0021510 4 0.041
negative regulation of cell motility GO:2000146 104 0.041
single organism cell adhesion GO:0098602 179 0.041
cellular amine metabolic process GO:0044106 41 0.041
stress fiber assembly GO:0043149 40 0.041
negative regulation of purine nucleotide metabolic process GO:1900543 28 0.040
negative regulation of ruffle assembly GO:1900028 3 0.040
response to oxygen levels GO:0070482 100 0.040
progesterone secretion GO:0042701 2 0.039
motor neuron axon guidance GO:0008045 2 0.038
regulation of nervous system development GO:0051960 88 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
cell cell signaling GO:0007267 155 0.038
growth GO:0040007 202 0.038
mitotic nuclear division GO:0007067 119 0.037
post golgi vesicle mediated transport GO:0006892 36 0.037
brain development GO:0007420 97 0.037
positive regulation of cellular amine metabolic process GO:0033240 7 0.036
regulation of response to external stimulus GO:0032101 222 0.035
regulation of stress fiber assembly GO:0051492 32 0.035
negative regulation of protein polymerization GO:0032272 16 0.035
endothelial cell proliferation GO:0001935 65 0.035
hippocampus development GO:0021766 1 0.035
negative regulation of cell death GO:0060548 345 0.034
spermatid differentiation GO:0048515 4 0.034
cell projection morphogenesis GO:0048858 129 0.033
biological adhesion GO:0022610 331 0.032
cell growth GO:0016049 160 0.032
neuron projection morphogenesis GO:0048812 50 0.032
nucleus localization GO:0051647 1 0.031
nitrogen compound transport GO:0071705 191 0.031
secretion GO:0046903 254 0.031
microtubule based process GO:0007017 210 0.030
regulation of endopeptidase activity GO:0052548 170 0.030
cd8 positive alpha beta t cell activation GO:0036037 3 0.030
cell morphogenesis involved in differentiation GO:0000904 144 0.030
tube development GO:0035295 125 0.030
endocrine hormone secretion GO:0060986 13 0.030
asymmetric stem cell division GO:0098722 1 0.029
internal peptidyl lysine acetylation GO:0018393 97 0.029
positive regulation of cell death GO:0010942 263 0.029
cellular response to organic cyclic compound GO:0071407 127 0.029
microtubule based movement GO:0007018 32 0.029
negative regulation of cellular component organization GO:0051129 235 0.029
Mouse
cellular response to abiotic stimulus GO:0071214 117 0.028
regulation of stress activated mapk cascade GO:0032872 84 0.028
i kappab kinase nf kappab signaling GO:0007249 166 0.028
ossification GO:0001503 121 0.028
negative regulation of developmental process GO:0051093 247 0.027
reproductive process GO:0022414 106 0.027
response to abiotic stimulus GO:0009628 336 0.027
regulation of lymphocyte activation GO:0051249 103 0.027
semaphorin plexin signaling pathway GO:0071526 4 0.027
cilium organization GO:0044782 68 0.027
determination of adult lifespan GO:0008340 2 0.027
cellular response to radiation GO:0071478 65 0.026
response to oxygen containing compound GO:1901700 369 0.025
negative regulation of cell migration GO:0030336 102 0.025
endosomal transport GO:0016197 129 0.025
maintenance of location GO:0051235 112 0.025
response to wounding GO:0009611 168 0.025
smoothened signaling pathway GO:0007224 14 0.024
positive regulation of ras gtpase activity GO:0032320 117 0.024
single organismal cell cell adhesion GO:0016337 148 0.024
primary neural tube formation GO:0014020 3 0.024
response to molecule of bacterial origin GO:0002237 82 0.024
embryo development GO:0009790 123 0.023
hair follicle morphogenesis GO:0031069 2 0.023
response to lipopolysaccharide GO:0032496 70 0.023
regulation of t cell activation GO:0050863 77 0.023
generation of neurons GO:0048699 152 0.023
regulation of cell cell adhesion mediated by cadherin GO:2000047 4 0.023
cell adhesion GO:0007155 325 0.023
negative regulation of actin filament bundle assembly GO:0032232 9 0.023
regulation of actin filament polymerization GO:0030833 50 0.023
negative regulation of catabolic process GO:0009895 104 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.022
response to growth factor GO:0070848 205 0.022
regulation of cell cycle GO:0051726 393 0.022
regulation of actin filament bundle assembly GO:0032231 36 0.022
neuron projection development GO:0031175 106 0.022
cytokinesis GO:0000910 96 0.022
defense response GO:0006952 315 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
system process GO:0003008 349 0.021
positive regulation of cell projection organization GO:0031346 64 0.021
multicellular organismal aging GO:0010259 3 0.021
actin filament based process GO:0030029 224 0.021
immune effector process GO:0002252 159 0.021
positive regulation of kinase activity GO:0033674 204 0.021
acetylcholine transport GO:0015870 1 0.021
leukocyte migration GO:0050900 107 0.021
positive regulation of ruffle assembly GO:1900029 4 0.020
response to organic cyclic compound GO:0014070 204 0.020
leukocyte activation GO:0045321 164 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
chromatin modification GO:0016568 298 0.020
regeneration GO:0031099 4 0.020
hormone secretion GO:0046879 65 0.020
response to biotic stimulus GO:0009607 276 0.020
negative regulation of locomotion GO:0040013 118 0.020
regulation of ras gtpase activity GO:0032318 128 0.020
spermatid development GO:0007286 4 0.020
endomembrane system organization GO:0010256 196 0.019
positive regulation of atpase activity GO:0032781 19 0.019
regulation of rho gtpase activity GO:0032319 66 0.019
limbic system development GO:0021761 3 0.018
negative regulation of cytoskeleton organization GO:0051494 45 0.018
cranial nerve development GO:0021545 4 0.018
regulation of cell development GO:0060284 161 0.018
negative regulation of organelle organization GO:0010639 126 0.018
regulation of neuron differentiation GO:0045664 70 0.018
mitotic cell cycle process GO:1903047 286 0.018
regulation of atp catabolic process GO:1903289 25 0.018
membrane organization GO:0061024 292 0.018
regulation of cytoskeleton organization GO:0051493 177 0.017
lipid metabolic process GO:0006629 381 0.017
renal water homeostasis GO:0003091 4 0.017
regulation of jnk cascade GO:0046328 73 0.017
regulation of cell growth GO:0001558 135 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
neuron projection extension GO:1990138 14 0.017
canonical wnt signaling pathway GO:0060070 116 0.017
response to tumor necrosis factor GO:0034612 76 0.017
protein oligomerization GO:0051259 173 0.017
head development GO:0060322 108 0.017
retinal ganglion cell axon guidance GO:0031290 2 0.017
jnk cascade GO:0007254 80 0.017
regulation of leukocyte activation GO:0002694 115 0.016
regulation of hormone secretion GO:0046883 57 0.016
regulation of actin cytoskeleton organization GO:0032956 116 0.016
negative regulation of epithelial cell migration GO:0010633 38 0.016
response to increased oxygen levels GO:0036296 4 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
fear response GO:0042596 0 0.016
cellular response to organonitrogen compound GO:0071417 124 0.016
positive regulation of actin filament bundle assembly GO:0032233 25 0.016
regulation of cellular response to stress GO:0080135 244 0.016
peptidyl serine phosphorylation GO:0018105 101 0.016
meiotic chromosome segregation GO:0045132 4 0.016
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.016
internal protein amino acid acetylation GO:0006475 101 0.016
establishment of organelle localization GO:0051656 59 0.016
tissue morphogenesis GO:0048729 96 0.016
positive regulation of t cell apoptotic process GO:0070234 4 0.015
actin polymerization or depolymerization GO:0008154 56 0.015
positive regulation of rho gtpase activity GO:0032321 56 0.015
axon development GO:0061564 34 0.015
regulation of cell adhesion GO:0030155 166 0.015
response to light stimulus GO:0009416 87 0.015
dephosphorylation GO:0016311 209 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
protein acylation GO:0043543 138 0.015
anoikis GO:0043276 22 0.015
negative regulation of cell growth GO:0030308 83 0.014
regulation of anatomical structure size GO:0090066 101 0.014
detection of stimulus GO:0051606 85 0.014
actin filament bundle organization GO:0061572 54 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
nuclear migration GO:0007097 1 0.014
cellular response to oxidative stress GO:0034599 85 0.014
regulation of cell shape GO:0008360 48 0.014
regulation of neuron projection development GO:0010975 57 0.014
dendritic spine morphogenesis GO:0060997 3 0.014
regulation of axonogenesis GO:0050770 16 0.014
regulation of cell projection assembly GO:0060491 47 0.014
regulation of locomotion GO:0040012 329 0.014
embryonic hindlimb morphogenesis GO:0035116 2 0.014
locomotory behavior GO:0007626 1 0.014
cellular ketone metabolic process GO:0042180 80 0.014
protein homooligomerization GO:0051260 100 0.014
behavioral defense response GO:0002209 0 0.014
regulation of hormone levels GO:0010817 125 0.014
protein localization to organelle GO:0033365 280 0.014
cilium morphogenesis GO:0060271 75 0.014
digestive tract morphogenesis GO:0048546 56 0.014
oxidative stress induced premature senescence GO:0090403 3 0.014
microtubule polymerization or depolymerization GO:0031109 37 0.013
negative regulation of actin nucleation GO:0051126 3 0.013
cellular biogenic amine catabolic process GO:0042402 4 0.013
negative regulation of angiogenesis GO:0016525 39 0.013
morphogenesis of an epithelium GO:0002009 60 0.013
polyamine catabolic process GO:0006598 2 0.013
positive regulation of t cell activation GO:0050870 54 0.013
covalent chromatin modification GO:0016569 254 0.013
regulation of histone deacetylation GO:0031063 9 0.013
phototransduction visible light GO:0007603 2 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.013
alcohol metabolic process GO:0006066 114 0.013
metal ion transport GO:0030001 272 0.013
ruffle organization GO:0031529 18 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
ras protein signal transduction GO:0007265 73 0.013
fibroblast proliferation GO:0048144 33 0.013
stem cell division GO:0017145 2 0.013
neuroblast division GO:0055057 1 0.013
organelle fission GO:0048285 149 0.013
epithelial cell migration GO:0010631 119 0.013
cell projection assembly GO:0030031 126 0.013
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of actin polymerization or depolymerization GO:0008064 56 0.012
microtubule based transport GO:0010970 21 0.012
immune response GO:0006955 307 0.012
regulation of ossification GO:0030278 58 0.012
double strand break repair GO:0006302 101 0.012
response to uv GO:0009411 73 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
uracil metabolic process GO:0019860 2 0.012
negative regulation of binding GO:0051100 57 0.012
pyrimidine nucleobase catabolic process GO:0006208 3 0.012
maintenance of protein localization in organelle GO:0072595 15 0.012
kidney interstitial fibroblast differentiation GO:0072071 2 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
multi organism reproductive process GO:0044703 54 0.012
developmental growth GO:0048589 48 0.012
embryonic morphogenesis GO:0048598 85 0.012
negative regulation of nucleoside metabolic process GO:0045978 18 0.012
collateral sprouting GO:0048668 2 0.012
cell cell junction organization GO:0045216 69 0.012
regulation of peptidyl serine phosphorylation GO:0033135 50 0.012
osteoblast differentiation GO:0001649 92 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
forelimb morphogenesis GO:0035136 4 0.012
behavioral fear response GO:0001662 0 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
positive regulation of cell activation GO:0050867 81 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
regulation of mapk cascade GO:0043408 262 0.012
response to nitrogen compound GO:1901698 184 0.012
developmental process involved in reproduction GO:0003006 66 0.012
neural nucleus development GO:0048857 47 0.011
protein maturation GO:0051604 233 0.011
regulation of dna metabolic process GO:0051052 153 0.011
tube closure GO:0060606 3 0.011
negative regulation of immune system process GO:0002683 136 0.011
positive regulation of autophagy GO:0010508 24 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
epithelium migration GO:0090132 119 0.011
positive regulation of alpha beta t cell activation GO:0046635 10 0.011
single organism membrane organization GO:0044802 268 0.011
polyamine metabolic process GO:0006595 4 0.011
regulation of cell cell adhesion GO:0022407 57 0.011
focal adhesion assembly GO:0048041 30 0.011
keratinocyte proliferation GO:0043616 17 0.011
protein folding GO:0006457 38 0.011
response to alcohol GO:0097305 64 0.011
neuron death GO:0070997 65 0.011
regulation of proteasomal protein catabolic process GO:0061136 87 0.011
response to external biotic stimulus GO:0043207 261 0.011
regulation of epithelial cell migration GO:0010632 93 0.011
regulation of homeostatic process GO:0032844 121 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.011
blastocyst development GO:0001824 3 0.011
negative regulation of ion transport GO:0043271 39 0.011
negative regulation of axonogenesis GO:0050771 4 0.011
apoptotic signaling pathway GO:0097190 268 0.011
response to interleukin 1 GO:0070555 47 0.011
positive regulation of blood pressure GO:0045777 3 0.011
peptidyl lysine acetylation GO:0018394 101 0.011
regulation of jun kinase activity GO:0043506 27 0.011
rna processing GO:0006396 255 0.010
regulation of smooth muscle cell proliferation GO:0048660 28 0.010
midgut development GO:0007494 1 0.010
regulation of cell cycle g1 s phase transition GO:1902806 42 0.010
negative regulation of myeloid cell differentiation GO:0045638 42 0.010
response to bacterium GO:0009617 144 0.010
myeloid leukocyte migration GO:0097529 62 0.010
chromosome segregation GO:0007059 114 0.010
neurological system process GO:0050877 163 0.010
regulation of cellular response to hepatocyte growth factor stimulus GO:2001112 1 0.010
leukocyte chemotaxis GO:0030595 76 0.010
cellular response to light stimulus GO:0071482 34 0.010
calcium ion transport GO:0006816 147 0.010
meiosis i GO:0007127 4 0.010
response to salt stress GO:0009651 3 0.010
nucleobase metabolic process GO:0009112 8 0.010
organelle localization GO:0051640 84 0.010

UNC119 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.093
nervous system disease DOID:863 431 0.093
neurodegenerative disease DOID:1289 102 0.016
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
musculoskeletal system disease DOID:17 223 0.013
retinal disease DOID:5679 118 0.011
night blindness DOID:8499 10 0.011
congenital stationary night blindness DOID:0050534 8 0.011
eye disease DOID:5614 149 0.011