Homo sapiens

25 known processes

WARS

tryptophanyl-tRNA synthetase

(Aliases: GAMMA-2,IFI53,IFP53)

WARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.205
Worm
nervous system development GO:0007399 293 0.158
determination of adult lifespan GO:0008340 2 0.142
cellular amino acid metabolic process GO:0006520 116 0.130
multicellular organismal aging GO:0010259 3 0.115
negative regulation of cell death GO:0060548 345 0.110
immune effector process GO:0002252 159 0.102
defense response GO:0006952 315 0.102
hematopoietic or lymphoid organ development GO:0048534 186 0.101
cellular macromolecule catabolic process GO:0044265 380 0.097
regulation of peptidase activity GO:0052547 180 0.092
chemical homeostasis GO:0048878 306 0.082
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.074
trna aminoacylation for protein translation GO:0006418 8 0.068
coenzyme metabolic process GO:0006732 65 0.068
transmembrane transport GO:0055085 399 0.068
negative regulation of catalytic activity GO:0043086 335 0.066
negative regulation of apoptotic process GO:0043066 316 0.065
cell type specific apoptotic process GO:0097285 125 0.063
inorganic ion transmembrane transport GO:0098660 231 0.062
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.061
oogenesis GO:0048477 2 0.060
negative regulation of programmed cell death GO:0043069 321 0.060
innate immune response GO:0045087 178 0.055
female gamete generation GO:0007292 2 0.053
cellular response to endogenous stimulus GO:0071495 336 0.053
regulation of endopeptidase activity GO:0052548 170 0.053
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.050
cellular response to cytokine stimulus GO:0071345 181 0.047
immune response GO:0006955 307 0.046
protein catabolic process GO:0030163 325 0.046
interspecies interaction between organisms GO:0044419 156 0.046
organonitrogen compound biosynthetic process GO:1901566 200 0.046
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.045
response to nitrogen compound GO:1901698 184 0.044
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.044
protein oligomerization GO:0051259 173 0.043
system process GO:0003008 349 0.042
modification dependent protein catabolic process GO:0019941 209 0.042
cellular homeostasis GO:0019725 196 0.041
regulation of proteolysis GO:0030162 293 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.040
syncytium formation by plasma membrane fusion GO:0000768 2 0.040
translation GO:0006412 132 0.040
cellular protein catabolic process GO:0044257 261 0.039
cofactor metabolic process GO:0051186 87 0.039
positive regulation of cell death GO:0010942 263 0.039
positive regulation of cell differentiation GO:0045597 211 0.038
viral process GO:0016032 146 0.036
positive regulation of developmental process GO:0051094 314 0.036
protein processing GO:0016485 226 0.035
cellular modified amino acid metabolic process GO:0006575 64 0.035
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.035
cellular chemical homeostasis GO:0055082 180 0.034
regulation of cellular ketone metabolic process GO:0010565 50 0.034
ncrna metabolic process GO:0034660 108 0.034
regulation of cell differentiation GO:0045595 393 0.033
positive regulation of hydrolase activity GO:0051345 331 0.033
vesicle mediated transport GO:0016192 371 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
response to endoplasmic reticulum stress GO:0034976 49 0.032
nucleoside phosphate biosynthetic process GO:1901293 109 0.032
response to biotic stimulus GO:0009607 276 0.031
biological adhesion GO:0022610 331 0.031
purine containing compound catabolic process GO:0072523 411 0.030
carbohydrate metabolic process GO:0005975 207 0.030
neurogenesis GO:0022008 169 0.030
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.029
positive regulation of peptidase activity GO:0010952 88 0.029
defense response to other organism GO:0098542 129 0.029
response to cytokine GO:0034097 232 0.029
atp catabolic process GO:0006200 157 0.029
regulation of cellular response to stress GO:0080135 244 0.028
leukocyte differentiation GO:0002521 98 0.028
response to organonitrogen compound GO:0010243 156 0.028
single organism membrane organization GO:0044802 268 0.028
response to external biotic stimulus GO:0043207 261 0.028
purine nucleoside catabolic process GO:0006152 398 0.028
organophosphate biosynthetic process GO:0090407 163 0.027
antigen processing and presentation GO:0019882 33 0.027
neurological system process GO:0050877 163 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.026
protein modification by small protein conjugation GO:0032446 342 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
cell development GO:0048468 328 0.025
nucleotide catabolic process GO:0009166 408 0.025
response to abiotic stimulus GO:0009628 336 0.025
cellular amine metabolic process GO:0044106 41 0.025
cellular ion homeostasis GO:0006873 168 0.025
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
regulation of protein catabolic process GO:0042176 155 0.024
response to bacterium GO:0009617 144 0.024
regulation of cell migration GO:0030334 289 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
ribonucleoside triphosphate catabolic process GO:0009203 391 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
negative regulation of developmental process GO:0051093 247 0.024
cellular protein complex assembly GO:0043623 188 0.023
alpha amino acid metabolic process GO:1901605 72 0.023
apoptotic signaling pathway GO:0097190 268 0.023
negative regulation of protein modification process GO:0031400 200 0.023
nucleoside monophosphate metabolic process GO:0009123 191 0.023
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.023
ribonucleoside monophosphate catabolic process GO:0009158 158 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
aging GO:0007568 66 0.022
nucleoside catabolic process GO:0009164 408 0.022
atp metabolic process GO:0046034 176 0.022
trna metabolic process GO:0006399 35 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
cellular component morphogenesis GO:0032989 314 0.021
protein homooligomerization GO:0051260 100 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
viral life cycle GO:0019058 132 0.020
positive regulation of endopeptidase activity GO:0010950 84 0.020
regeneration GO:0031099 4 0.020
positive regulation of proteolysis GO:0045862 142 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.019
purine nucleoside monophosphate metabolic process GO:0009126 186 0.019
epithelium development GO:0060429 227 0.019
regulation of ion transport GO:0043269 189 0.019
regulation of transferase activity GO:0051338 355 0.019
rna processing GO:0006396 255 0.019
purine nucleoside monophosphate catabolic process GO:0009128 158 0.019
ion homeostasis GO:0050801 230 0.019
positive regulation of programmed cell death GO:0043068 249 0.019
response to other organism GO:0051707 261 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
single organism cellular localization GO:1902580 332 0.019
regulation of cellular component movement GO:0051270 334 0.019
protein maturation GO:0051604 233 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.018
dicarboxylic acid metabolic process GO:0043648 29 0.018
negative regulation of locomotion GO:0040013 118 0.018
cell projection organization GO:0030030 252 0.018
negative regulation of multi organism process GO:0043901 92 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.017
cell morphogenesis GO:0000902 296 0.017
generation of precursor metabolites and energy GO:0006091 68 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
leukocyte mediated cytotoxicity GO:0001909 27 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
defense response to virus GO:0051607 71 0.017
regulation of intracellular transport GO:0032386 195 0.017
regulation of viral process GO:0050792 103 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
positive regulation of cellular component organization GO:0051130 376 0.016
purine ribonucleoside catabolic process GO:0046130 398 0.016
ribonucleotide catabolic process GO:0009261 405 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
cytoplasmic transport GO:0016482 379 0.016
multi organism cellular process GO:0044764 156 0.016
embryo development GO:0009790 123 0.016
Worm
cation transmembrane transport GO:0098655 238 0.016
regulation of cell motility GO:2000145 299 0.016
spermatid development GO:0007286 4 0.016
maintenance of location GO:0051235 112 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.015
cardiovascular system development GO:0072358 262 0.015
regulation of anatomical structure size GO:0090066 101 0.015
response to interferon gamma GO:0034341 39 0.015
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
mitotic cell cycle GO:0000278 326 0.015
metencephalon development GO:0022037 2 0.015
endomembrane system organization GO:0010256 196 0.015
cellular cation homeostasis GO:0030003 163 0.015
positive regulation of immune system process GO:0002684 283 0.015
response to oxygen containing compound GO:1901700 369 0.015
response to axon injury GO:0048678 1 0.015
mitotic spindle elongation GO:0000022 4 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
myeloid cell homeostasis GO:0002262 34 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
neuron apoptotic process GO:0051402 39 0.014
endocytosis GO:0006897 159 0.014
cation homeostasis GO:0055080 189 0.014
regulation of cellular protein catabolic process GO:1903362 96 0.014
secretion GO:0046903 254 0.014
neuron death GO:0070997 65 0.014
myosin filament organization GO:0031033 2 0.014
actin cytoskeleton organization GO:0030036 207 0.014
cation transport GO:0006812 331 0.014
regulation of kinase activity GO:0043549 314 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
lipid metabolic process GO:0006629 381 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
regulation of cellular amine metabolic process GO:0033238 11 0.013
amino acid activation GO:0043038 12 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
leukocyte activation GO:0045321 164 0.013
cell activation GO:0001775 213 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
sulfur compound metabolic process GO:0006790 101 0.013
membrane organization GO:0061024 292 0.013
actin filament based process GO:0030029 224 0.013
protein ubiquitination GO:0016567 314 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
regulation of locomotion GO:0040012 329 0.013
angiogenesis GO:0001525 147 0.012
mitochondrion organization GO:0007005 156 0.012
myoblast fusion GO:0007520 1 0.012
leukocyte mediated immunity GO:0002443 59 0.012
ion transmembrane transport GO:0034220 338 0.012
negative regulation of cell migration GO:0030336 102 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.012
single organism reproductive process GO:0044702 98 0.012
ncrna processing GO:0034470 83 0.012
response to virus GO:0009615 126 0.012
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
organelle assembly GO:0070925 176 0.012
regulation of translation GO:0006417 89 0.012
cellular ketone metabolic process GO:0042180 80 0.012
regulation of membrane potential GO:0042391 95 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
Worm
inorganic cation transmembrane transport GO:0098662 194 0.012
cellular response to glucocorticoid stimulus GO:0071385 4 0.012
response to oxidative stress GO:0006979 121 0.011
cellular divalent inorganic cation homeostasis GO:0072503 128 0.011
plasma membrane organization GO:0007009 115 0.011
response to peptidoglycan GO:0032494 3 0.011
regulation of viral genome replication GO:0045069 48 0.011
hindbrain development GO:0030902 3 0.011
divalent inorganic cation transport GO:0072511 158 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
vasodilation GO:0042311 4 0.011
spermatid differentiation GO:0048515 4 0.011
intracellular protein transport GO:0006886 270 0.011
cellular calcium ion homeostasis GO:0006874 117 0.011
protein acylation GO:0043543 138 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
secretion by cell GO:0032940 226 0.011
negative regulation of cell motility GO:2000146 104 0.011
immune system development GO:0002520 195 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.011
rna catabolic process GO:0006401 71 0.011
glucose metabolic process GO:0006006 45 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
cell part morphogenesis GO:0032990 137 0.011
carboxylic acid catabolic process GO:0046395 71 0.010
generation of neurons GO:0048699 152 0.010
natural killer cell mediated cytotoxicity GO:0042267 23 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.010
cell projection assembly GO:0030031 126 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
antigen processing and presentation of exogenous antigen GO:0019884 4 0.010
internal protein amino acid acetylation GO:0006475 101 0.010
regulation of binding GO:0051098 111 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
anion transport GO:0006820 161 0.010
regulation of homeostatic process GO:0032844 121 0.010

WARS disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.024
neuropathy DOID:870 52 0.024
immune system disease DOID:2914 155 0.023
neuromuscular disease DOID:440 38 0.019
central nervous system disease DOID:331 186 0.019
musculoskeletal system disease DOID:17 223 0.019
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
organ system cancer DOID:0050686 164 0.017
bone disease DOID:0080001 88 0.012
connective tissue disease DOID:65 109 0.012
disease of metabolism DOID:0014667 295 0.012
sensory system disease DOID:0050155 203 0.012
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011
charcot marie tooth disease DOID:10595 33 0.011