Homo sapiens

0 known processes

THOP1

thimet oligopeptidase 1

(Aliases: EP24.15,MP78,TOP,MEPD_HUMAN)

THOP1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
multicellular organismal aging GO:0010259 3 0.285
post embryonic development GO:0009791 2 0.173
cellular amino acid metabolic process GO:0006520 116 0.168
determination of adult lifespan GO:0008340 2 0.165
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.100
nucleoside phosphate catabolic process GO:1901292 412 0.080
purine ribonucleoside metabolic process GO:0046128 437 0.080
vesicle mediated transport GO:0016192 371 0.072
regulation of cell cycle GO:0051726 393 0.070
ribonucleoside triphosphate catabolic process GO:0009203 391 0.066
nucleotide catabolic process GO:0009166 408 0.065
purine ribonucleotide biosynthetic process GO:0009152 79 0.062
protein catabolic process GO:0030163 325 0.062
cellular amine metabolic process GO:0044106 41 0.061
positive regulation of developmental process GO:0051094 314 0.059
rna processing GO:0006396 255 0.058
locomotory behavior GO:0007626 1 0.056
regulation of cellular ketone metabolic process GO:0010565 50 0.056
ribonucleotide catabolic process GO:0009261 405 0.055
ncrna metabolic process GO:0034660 108 0.055
single organism cellular localization GO:1902580 332 0.055
ribonucleoside triphosphate metabolic process GO:0009199 412 0.053
ribonucleoside catabolic process GO:0042454 406 0.053
positive regulation of cellular amine metabolic process GO:0033240 7 0.052
purine nucleoside triphosphate catabolic process GO:0009146 392 0.050
purine nucleotide catabolic process GO:0006195 405 0.050
amine metabolic process GO:0009308 44 0.049
regulation of cellular amine metabolic process GO:0033238 11 0.049
purine ribonucleoside catabolic process GO:0046130 398 0.048
purine containing compound catabolic process GO:0072523 411 0.047
cellular ketone metabolic process GO:0042180 80 0.047
regulation of cellular amino acid metabolic process GO:0006521 6 0.045
endocytosis GO:0006897 159 0.045
negative regulation of cell cycle GO:0045786 193 0.045
cellular macromolecule catabolic process GO:0044265 380 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.043
cellular macromolecular complex assembly GO:0034622 324 0.043
glycosyl compound catabolic process GO:1901658 413 0.043
nucleoside triphosphate catabolic process GO:0009143 394 0.042
nucleoside catabolic process GO:0009164 408 0.042
cellular protein catabolic process GO:0044257 261 0.041
fatty acid metabolic process GO:0006631 115 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.037
mitochondrial rna metabolic process GO:0000959 15 0.036
meiotic chromosome segregation GO:0045132 4 0.034
purine ribonucleotide catabolic process GO:0009154 404 0.034
nucleoside triphosphate metabolic process GO:0009141 422 0.033
microtubule based process GO:0007017 210 0.032
embryo development GO:0009790 123 0.032
atp catabolic process GO:0006200 157 0.031
nuclear migration GO:0007097 1 0.031
organophosphate catabolic process GO:0046434 430 0.030
organonitrogen compound biosynthetic process GO:1901566 200 0.030
growth GO:0040007 202 0.030
cell development GO:0048468 328 0.029
cell cell signaling GO:0007267 155 0.029
sulfate transmembrane transport GO:1902358 3 0.028
cell cycle checkpoint GO:0000075 117 0.028
protein modification by small protein conjugation GO:0032446 342 0.028
regulation of growth GO:0040008 165 0.028
organophosphate biosynthetic process GO:0090407 163 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.026
mitotic cell cycle GO:0000278 326 0.026
actin filament based process GO:0030029 224 0.026
adult locomotory behavior GO:0008344 1 0.025
female gamete generation GO:0007292 2 0.025
dna recombination GO:0006310 77 0.025
cell cycle arrest GO:0007050 71 0.025
atp metabolic process GO:0046034 176 0.025
nervous system development GO:0007399 293 0.024
regulation of protein localization GO:0032880 296 0.024
cellular protein complex assembly GO:0043623 188 0.024
oogenesis GO:0048477 2 0.023
cellular component morphogenesis GO:0032989 314 0.023
rna splicing GO:0008380 131 0.022
secretion GO:0046903 254 0.022
enzyme linked receptor protein signaling pathway GO:0007167 303 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.022
intracellular protein transport GO:0006886 270 0.022
mitochondrion organization GO:0007005 156 0.021
dephosphorylation GO:0016311 209 0.021
positive regulation of cell proliferation GO:0008284 301 0.021
nucleotide biosynthetic process GO:0009165 109 0.021
neurogenesis GO:0022008 169 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.021
nucleoside phosphate biosynthetic process GO:1901293 109 0.020
protein localization to organelle GO:0033365 280 0.020
positive regulation of organelle organization GO:0010638 195 0.020
response to hypoxia GO:0001666 96 0.020
response to abiotic stimulus GO:0009628 336 0.020
regulation of transferase activity GO:0051338 355 0.020
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
immune system development GO:0002520 195 0.019
oocyte differentiation GO:0009994 2 0.018
regulation of ras gtpase activity GO:0032318 128 0.018
cell projection organization GO:0030030 252 0.018
single organism membrane organization GO:0044802 268 0.018
transcription from mitochondrial promoter GO:0006390 7 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
trna metabolic process GO:0006399 35 0.018
proteasomal protein catabolic process GO:0010498 176 0.017
spermatid development GO:0007286 4 0.017
gtp metabolic process GO:0046039 239 0.017
regulation of establishment of protein localization GO:0070201 242 0.016
histone modification GO:0016570 251 0.016
protein localization to nucleus GO:0034504 136 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
response to biotic stimulus GO:0009607 276 0.016
regulation of secretion GO:0051046 194 0.016
cell division GO:0051301 168 0.016
nucleus organization GO:0006997 28 0.016
nuclear division GO:0000280 128 0.016
reproduction GO:0000003 63 0.015
cell morphogenesis GO:0000902 296 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
single organism reproductive process GO:0044702 98 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
positive regulation of catabolic process GO:0009896 310 0.015
cell growth GO:0016049 160 0.015
cell cycle phase transition GO:0044770 173 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
ribonucleoprotein complex subunit organization GO:0071826 81 0.015
protein oligomerization GO:0051259 173 0.015
spliceosomal snrnp assembly GO:0000387 28 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
covalent chromatin modification GO:0016569 254 0.015
response to oxygen levels GO:0070482 100 0.015
aging GO:0007568 66 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
nucleus localization GO:0051647 1 0.014
chemical homeostasis GO:0048878 306 0.014
developmental process involved in reproduction GO:0003006 66 0.014
hemopoiesis GO:0030097 180 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
mitotic cell cycle process GO:1903047 286 0.014
ribonucleotide biosynthetic process GO:0009260 81 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.013
membrane organization GO:0061024 292 0.013
myosin filament organization GO:0031033 2 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
inorganic anion transport GO:0015698 60 0.013
immune response GO:0006955 307 0.013
myosin filament assembly GO:0031034 2 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
dna integrity checkpoint GO:0031570 71 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
positive regulation of cell death GO:0010942 263 0.013
organelle assembly GO:0070925 176 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
protein ubiquitination GO:0016567 314 0.013
chromatin organization GO:0006325 351 0.012
regulation of proteolysis GO:0030162 293 0.012
protein targeting to nucleus GO:0044744 104 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
ribonucleoprotein complex assembly GO:0022618 78 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
response to decreased oxygen levels GO:0036293 96 0.012
nuclear transport GO:0051169 179 0.012
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.012
dna replication GO:0006260 116 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
neuron development GO:0048666 113 0.012
reproductive system development GO:0061458 56 0.012
purine nucleoside catabolic process GO:0006152 398 0.012
spermatid differentiation GO:0048515 4 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
regulation of dna metabolic process GO:0051052 153 0.012
positive regulation of camp biosynthetic process GO:0030819 35 0.012
inorganic anion transmembrane transport GO:0098661 47 0.011
negative regulation of developmental process GO:0051093 247 0.011
cell projection assembly GO:0030031 126 0.011
gene silencing GO:0016458 49 0.011
regulation of cell cycle process GO:0010564 266 0.011
lipid metabolic process GO:0006629 381 0.011
maintenance of location GO:0051235 112 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
cell projection morphogenesis GO:0048858 129 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
establishment of nucleus localization GO:0040023 1 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
receptor mediated endocytosis GO:0006898 84 0.011
mrna metabolic process GO:0016071 175 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
oocyte development GO:0048599 1 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
protein dephosphorylation GO:0006470 81 0.011
peptidyl lysine modification GO:0018205 144 0.010
reproductive process GO:0022414 106 0.010
regulation of protein transport GO:0051223 213 0.010
regulation of gene expression epigenetic GO:0040029 73 0.010
cellular component assembly involved in morphogenesis GO:0010927 73 0.010
ion homeostasis GO:0050801 230 0.010
positive regulation of hydrolase activity GO:0051345 331 0.010
response to other organism GO:0051707 261 0.010
microtubule organizing center organization GO:0031023 62 0.010
dna damage checkpoint GO:0000077 68 0.010

THOP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.052
disease of cellular proliferation DOID:14566 174 0.052
organ system cancer DOID:0050686 164 0.052
disease of metabolism DOID:0014667 295 0.017
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011