Homo sapiens

77 known processes

BHLHE40

basic helix-loop-helix family, member e40

(Aliases: HLHB2,BHLHB2,Stra14,STRA13,FLJ99214,DEC1,SHARP-2)

BHLHE40 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.993
hematopoietic or lymphoid organ development GO:0048534 186 0.815
cellular response to endogenous stimulus GO:0071495 336 0.811
positive regulation of cell differentiation GO:0045597 211 0.772
immune system development GO:0002520 195 0.662
urate metabolic process GO:0046415 11 0.593
cell development GO:0048468 328 0.585
negative regulation of protein metabolic process GO:0051248 391 0.580
enzyme linked receptor protein signaling pathway GO:0007167 303 0.545
circulatory system development GO:0072359 262 0.521
vascular wound healing GO:0061042 4 0.476
post embryonic development GO:0009791 2 0.476
positive regulation of developmental process GO:0051094 314 0.456
response to oxygen containing compound GO:1901700 369 0.448
neurofilament bundle assembly GO:0033693 2 0.430
cellular response to growth factor stimulus GO:0071363 197 0.415
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.395
regulation of cell cycle GO:0051726 393 0.392
regulation of transferase activity GO:0051338 355 0.372
mitotic cell cycle GO:0000278 326 0.372
amine metabolic process GO:0009308 44 0.368
regulation of cellular ketone metabolic process GO:0010565 50 0.358
apoptotic signaling pathway GO:0097190 268 0.334
regeneration GO:0031099 4 0.325
epithelium development GO:0060429 227 0.308
positive regulation of apoptotic process GO:0043065 246 0.297
negative regulation of cell differentiation GO:0045596 171 0.294
locomotory behavior GO:0007626 1 0.293
Zebrafish
response to growth factor GO:0070848 205 0.291
negative regulation of cellular protein metabolic process GO:0032269 353 0.286
embryonic placenta development GO:0001892 1 0.278
cellular amino acid metabolic process GO:0006520 116 0.276
carbohydrate metabolic process GO:0005975 207 0.272
positive regulation of p38mapk cascade GO:1900745 8 0.271
regulation of cell differentiation GO:0045595 393 0.265
negative regulation of cell death GO:0060548 345 0.264
erk1 and erk2 cascade GO:0070371 104 0.261
regulation of mitosis GO:0007088 63 0.248
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.247
response to nitrosative stress GO:0051409 4 0.237
cell cycle phase transition GO:0044770 173 0.236
regulation of cellular response to stress GO:0080135 244 0.235
epithelial cell differentiation GO:0030855 141 0.233
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 2 0.220
regulation of cell cycle process GO:0010564 266 0.215
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 0.215
vasculature development GO:0001944 181 0.205
protein acetylation GO:0006473 116 0.201
smad protein signal transduction GO:0060395 10 0.199
cellular amine metabolic process GO:0044106 41 0.197
cellular response to dna damage stimulus GO:0006974 379 0.196
intrinsic apoptotic signaling pathway GO:0097193 127 0.196
response to metal ion GO:0010038 84 0.183
hemopoiesis GO:0030097 180 0.180
cellular response to oxygen containing compound GO:1901701 276 0.175
positive regulation of catabolic process GO:0009896 310 0.167
cardiovascular system development GO:0072358 262 0.164
growth GO:0040007 202 0.159
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.157
myeloid cell differentiation GO:0030099 117 0.157
ion transmembrane transport GO:0034220 338 0.155
positive regulation of histone deacetylase activity GO:1901727 3 0.152
regulation of cellular amino acid metabolic process GO:0006521 6 0.151
negative regulation of apoptotic process GO:0043066 316 0.149
cell projection organization GO:0030030 252 0.148
protein processing GO:0016485 226 0.147
regulation of protein serine threonine kinase activity GO:0071900 179 0.147
cellular response to nitrogen compound GO:1901699 144 0.146
lipid biosynthetic process GO:0008610 177 0.145
covalent chromatin modification GO:0016569 254 0.144
negative regulation of protein modification process GO:0031400 200 0.144
lung alveolus development GO:0048286 4 0.143
carbohydrate biosynthetic process GO:0016051 42 0.141
determination of adult lifespan GO:0008340 2 0.140
negative regulation of cellular component organization GO:0051129 235 0.139
negative regulation of cellular carbohydrate metabolic process GO:0010677 14 0.139
protein localization to organelle GO:0033365 280 0.136
monocarboxylic acid metabolic process GO:0032787 185 0.132
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.129
mitotic cell cycle process GO:1903047 286 0.128
regulation of vascular wound healing GO:0061043 2 0.127
mitotic cell cycle phase transition GO:0044772 162 0.125
positive regulation of gliogenesis GO:0014015 4 0.122
positive regulation of cell proliferation GO:0008284 301 0.122
negative regulation of response to wounding GO:1903035 47 0.115
cellular macromolecule catabolic process GO:0044265 380 0.114
positive regulation of programmed cell death GO:0043068 249 0.114
fibroblast proliferation GO:0048144 33 0.113
negative regulation of cellular amine metabolic process GO:0033239 3 0.111
regulation of cell division GO:0051302 116 0.111
vascular smooth muscle cell development GO:0097084 1 0.111
blood vessel development GO:0001568 172 0.111
chromatin modification GO:0016568 298 0.106
cell division GO:0051301 168 0.105
response to organic cyclic compound GO:0014070 204 0.104
negative regulation of developmental process GO:0051093 247 0.104
regulation of cell development GO:0060284 161 0.099
nerve development GO:0021675 4 0.099
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.098
female gamete generation GO:0007292 2 0.098
protein modification by small protein conjugation GO:0032446 342 0.097
positive regulation of vascular wound healing GO:0035470 1 0.097
negative regulation of erythrocyte differentiation GO:0045647 3 0.096
angiogenesis involved in wound healing GO:0060055 4 0.096
negative regulation of protein maturation GO:1903318 142 0.096
negative regulation of programmed cell death GO:0043069 321 0.095
regulation of proteolysis GO:0030162 293 0.095
response to extracellular stimulus GO:0009991 85 0.094
rhythmic behavior GO:0007622 2 0.093
Zebrafish
regulation of mitotic cell cycle GO:0007346 189 0.093
dna repair GO:0006281 198 0.093
cellular response to organic cyclic compound GO:0071407 127 0.093
histone modification GO:0016570 251 0.092
response to abiotic stimulus GO:0009628 336 0.092
Mouse Rat
collateral sprouting GO:0048668 2 0.091
regulation of kinase activity GO:0043549 314 0.089
neurofilament cytoskeleton organization GO:0060052 2 0.089
cellular carbohydrate metabolic process GO:0044262 84 0.088
regulation of mast cell chemotaxis GO:0060753 4 0.086
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.086
single organism reproductive process GO:0044702 98 0.086
cellular response to radiation GO:0071478 65 0.085
protein acylation GO:0043543 138 0.085
microtubule based process GO:0007017 210 0.085
response to hypoxia GO:0001666 96 0.085
positive regulation of cell development GO:0010720 92 0.085
peptidyl lysine modification GO:0018205 144 0.085
chromatin organization GO:0006325 351 0.083
response to organonitrogen compound GO:0010243 156 0.082
negative regulation of phosphatidylinositol biosynthetic process GO:0010512 2 0.081
regulation of glomerulus development GO:0090192 3 0.080
response to transforming growth factor beta GO:0071559 94 0.080
cellular ketone metabolic process GO:0042180 80 0.078
peptidyl lysine acetylation GO:0018394 101 0.078
cellular response to ionizing radiation GO:0071479 32 0.077
negative regulation of phosphorus metabolic process GO:0010563 267 0.076
response to biotic stimulus GO:0009607 276 0.076
negative regulation of cell cycle process GO:0010948 121 0.076
negative regulation of organelle organization GO:0010639 126 0.075
positive regulation of mast cell chemotaxis GO:0060754 4 0.075
regulation of circadian rhythm GO:0042752 11 0.075
Mouse Rat
vesicle mediated transport GO:0016192 371 0.074
regulation of glial cell proliferation GO:0060251 4 0.074
hematopoietic progenitor cell differentiation GO:0002244 38 0.074
nervous system development GO:0007399 293 0.073
circadian rhythm GO:0007623 21 0.072
negative regulation of catalytic activity GO:0043086 335 0.072
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.070
neuron projection regeneration GO:0031102 1 0.069
regulation of growth GO:0040008 165 0.069
negative regulation of response to external stimulus GO:0032102 83 0.069
basophil chemotaxis GO:0002575 1 0.069
histone h3 acetylation GO:0043966 45 0.069
negative regulation of homeostatic process GO:0032845 59 0.068
regulation of endopeptidase activity GO:0052548 170 0.068
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.067
viral life cycle GO:0019058 132 0.067
generation of precursor metabolites and energy GO:0006091 68 0.066
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.065
negative regulation of cell cycle GO:0045786 193 0.065
regulation of axon guidance GO:1902667 3 0.065
negative regulation of proteolysis GO:0045861 132 0.064
negative regulation of catabolic process GO:0009895 104 0.063
regulation of protein kinase activity GO:0045859 289 0.062
positive regulation of cellular amine metabolic process GO:0033240 7 0.062
mapk cascade GO:0000165 288 0.061
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.061
negative regulation of phosphate metabolic process GO:0045936 267 0.061
anatomical structure formation involved in morphogenesis GO:0048646 284 0.061
single organism membrane organization GO:0044802 268 0.061
regulation of neural precursor cell proliferation GO:2000177 4 0.060
multicellular organismal aging GO:0010259 3 0.059
nephron morphogenesis GO:0072028 15 0.059
regulation of carbohydrate metabolic process GO:0006109 54 0.059
epidermis development GO:0008544 59 0.058
cellular response to cytokine stimulus GO:0071345 181 0.058
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.057
negative regulation of mitotic cell cycle GO:0045930 102 0.057
positive regulation of hemoglobin biosynthetic process GO:0046985 1 0.057
secretion GO:0046903 254 0.057
response to radiation GO:0009314 151 0.056
Mouse Rat
cell morphogenesis involved in differentiation GO:0000904 144 0.056
response to fibroblast growth factor GO:0071774 39 0.056
positive regulation of peptidyl tyrosine autophosphorylation GO:1900086 1 0.056
apoptotic mitochondrial changes GO:0008637 57 0.056
protein catabolic process GO:0030163 325 0.056
developmental growth involved in morphogenesis GO:0060560 23 0.055
developmental growth GO:0048589 48 0.054
muscle tissue development GO:0060537 62 0.054
defense response GO:0006952 315 0.054
positive regulation of glial cell proliferation GO:0060252 2 0.054
regulation of cell growth GO:0001558 135 0.054
mitochondrial outer membrane permeabilization GO:0097345 15 0.054
proteasomal protein catabolic process GO:0010498 176 0.054
response to estrogen GO:0043627 47 0.053
organ morphogenesis GO:0009887 147 0.053
positive regulation of cellular catabolic process GO:0031331 284 0.052
negative regulation of protein processing GO:0010955 142 0.052
protein ubiquitination GO:0016567 314 0.052
response to ionizing radiation GO:0010212 65 0.052
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.052
negative regulation of intracellular signal transduction GO:1902532 183 0.051
cell projection morphogenesis GO:0048858 129 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.050
positive regulation of cell death GO:0010942 263 0.050
negative regulation of cell proliferation GO:0008285 228 0.049
endocytosis GO:0006897 159 0.049
multi organism cellular process GO:0044764 156 0.049
glomerular mesangial cell proliferation GO:0072110 3 0.049
regulation of dna repair GO:0006282 47 0.048
chemical homeostasis GO:0048878 306 0.048
regulation of mitochondrial membrane permeability GO:0046902 25 0.048
signal transduction in response to dna damage GO:0042770 57 0.048
muscle structure development GO:0061061 98 0.048
protein maturation GO:0051604 233 0.048
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.048
regulation of reactive oxygen species metabolic process GO:2000377 41 0.048
blood vessel morphogenesis GO:0048514 162 0.047
ossification GO:0001503 121 0.047
negative regulation of apoptotic signaling pathway GO:2001234 97 0.046
response to oxygen levels GO:0070482 100 0.046
neuron projection development GO:0031175 106 0.046
protein dephosphorylation GO:0006470 81 0.046
skin development GO:0043588 76 0.046
single organism carbohydrate metabolic process GO:0044723 193 0.046
metanephric mesenchymal cell migration GO:0035789 2 0.046
generation of neurons GO:0048699 152 0.046
response to other organism GO:0051707 261 0.045
neuron differentiation GO:0030182 138 0.045
transmembrane transport GO:0055085 399 0.045
regulation of cellular amine metabolic process GO:0033238 11 0.044
positive regulation of mesonephros development GO:0061213 2 0.044
endothelial cell migration GO:0043542 86 0.043
regulation of axon extension involved in axon guidance GO:0048841 2 0.043
modification dependent protein catabolic process GO:0019941 209 0.043
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.043
neuron development GO:0048666 113 0.043
regulation of protein maturation GO:1903317 150 0.042
vitamin transport GO:0051180 14 0.042
glucose homeostasis GO:0042593 31 0.042
membrane organization GO:0061024 292 0.042
monosaccharide metabolic process GO:0005996 74 0.042
regulation of anatomical structure morphogenesis GO:0022603 286 0.042
epidermal cell differentiation GO:0009913 45 0.041
response to decreased oxygen levels GO:0036293 96 0.041
protein autophosphorylation GO:0046777 123 0.041
response to nutrient levels GO:0031667 81 0.041
regulation of hormone levels GO:0010817 125 0.041
regulation of epidermis development GO:0045682 19 0.041
secretion by cell GO:0032940 226 0.041
cranial nerve development GO:0021545 4 0.040
ubiquitin dependent protein catabolic process GO:0006511 206 0.040
system process GO:0003008 349 0.040
lung vasculature development GO:0060426 2 0.040
neuromuscular junction development GO:0007528 3 0.040
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.040
regulation of erk1 and erk2 cascade GO:0070372 99 0.040
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.040
regulation of metal ion transport GO:0010959 120 0.040
cellular component morphogenesis GO:0032989 314 0.040
purine containing compound catabolic process GO:0072523 411 0.040
oxidation reduction process GO:0055114 396 0.040
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.040
cellular lipid metabolic process GO:0044255 303 0.039
response to wounding GO:0009611 168 0.039
neuron projection morphogenesis GO:0048812 50 0.039
single organism cellular localization GO:1902580 332 0.038
neurogenesis GO:0022008 169 0.038
cell part morphogenesis GO:0032990 137 0.038
erythrocyte differentiation GO:0030218 28 0.037
cell cycle checkpoint GO:0000075 117 0.037
regulation of cytokine production GO:0001817 232 0.037
circadian behavior GO:0048512 2 0.036
Zebrafish
central nervous system development GO:0007417 123 0.036
modification dependent macromolecule catabolic process GO:0043632 212 0.036
metal ion transport GO:0030001 272 0.036
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.036
osteoblast differentiation GO:0001649 92 0.036
response to hexose GO:0009746 20 0.035
positive regulation of immune system process GO:0002684 283 0.035
cellular protein catabolic process GO:0044257 261 0.035
posttranscriptional regulation of gene expression GO:0010608 213 0.035
regulation of stress activated mapk cascade GO:0032872 84 0.035
tube development GO:0035295 125 0.035
circulatory system process GO:0003013 113 0.035
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 2 0.034
negative regulation of protein phosphorylation GO:0001933 140 0.034
cellular response to organonitrogen compound GO:0071417 124 0.034
response to nitrogen compound GO:1901698 184 0.034
glycolytic process GO:0006096 17 0.033
post embryonic organ development GO:0048569 1 0.033
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.033
urogenital system development GO:0001655 65 0.033
cell growth GO:0016049 160 0.033
regulation of system process GO:0044057 101 0.033
nucleoside triphosphate metabolic process GO:0009141 422 0.033
astrocyte differentiation GO:0048708 4 0.033
regulation of histone modification GO:0031056 47 0.033
cellular response to abiotic stimulus GO:0071214 117 0.033
single organism carbohydrate catabolic process GO:0044724 33 0.033
cell morphogenesis GO:0000902 296 0.033
cellular response to external stimulus GO:0071496 111 0.032
interspecies interaction between organisms GO:0044419 156 0.032
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.032
negative regulation of cell cycle phase transition GO:1901988 89 0.032
muscle cell differentiation GO:0042692 63 0.032
lipid metabolic process GO:0006629 381 0.032
negative regulation of kinase activity GO:0033673 106 0.031
mitotic nuclear division GO:0007067 119 0.031
rhythmic process GO:0048511 31 0.031
regulation of jnk cascade GO:0046328 73 0.031
lymphocyte proliferation GO:0046651 70 0.031
cellular response to glucocorticoid stimulus GO:0071385 4 0.031
regulation of cell cycle phase transition GO:1901987 126 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.030
positive regulation of stress activated mapk cascade GO:0032874 60 0.030
cytokine production GO:0001816 247 0.030
negative regulation of transferase activity GO:0051348 124 0.030
embryo development GO:0009790 123 0.030
response to external biotic stimulus GO:0043207 261 0.030
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.030
regulation of nervous system development GO:0051960 88 0.030
stress activated mapk cascade GO:0051403 93 0.030
regulation of mitotic cell cycle phase transition GO:1901990 118 0.030
regulation of cell morphogenesis GO:0022604 153 0.029
regulation of response to dna damage stimulus GO:2001020 94 0.029
regulation of nuclear division GO:0051783 65 0.029
cellular response to lipid GO:0071396 127 0.029
mitochondrion organization GO:0007005 156 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
mitochondrial transport GO:0006839 60 0.029
purine ribonucleoside metabolic process GO:0046128 437 0.029
response to inorganic substance GO:0010035 127 0.029
reproductive system development GO:0061458 56 0.029
regulation of myeloid cell differentiation GO:0045637 81 0.029
inflammatory response GO:0006954 79 0.028
jnk cascade GO:0007254 80 0.028
blood vessel endothelial cell migration GO:0043534 42 0.028
immune response GO:0006955 307 0.028
negative regulation of transport GO:0051051 176 0.028
rna interference GO:0016246 4 0.028
cation transport GO:0006812 331 0.028
signal transduction by p53 class mediator GO:0072331 72 0.028
regulation of protein ubiquitination GO:0031396 95 0.028
regulation of dna metabolic process GO:0051052 153 0.028
regulation of mesonephros development GO:0061217 3 0.028
chordate embryonic development GO:0043009 34 0.028
myeloid leukocyte differentiation GO:0002573 60 0.028
regulation of neuroblast proliferation GO:1902692 3 0.027
embryonic organ development GO:0048568 36 0.027
histone deacetylation GO:0016575 32 0.027
positive regulation of peptidyl serine phosphorylation of stat protein GO:0033141 3 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.027
carbohydrate catabolic process GO:0016052 36 0.026
response to peptide GO:1901652 65 0.026
adult locomotory behavior GO:0008344 1 0.026
aging GO:0007568 66 0.026
axonogenesis GO:0007409 31 0.026
ectoderm development GO:0007398 3 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.026
response to drug GO:0042493 81 0.026
positive regulation of ion transport GO:0043270 87 0.026
brain development GO:0007420 97 0.026
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.025
regulation of cell projection organization GO:0031344 107 0.025
regulation of cell activation GO:0050865 125 0.025
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.025
cell migration involved in sprouting angiogenesis GO:0002042 19 0.025
rna processing GO:0006396 255 0.025
glucose metabolic process GO:0006006 45 0.025
organelle fission GO:0048285 149 0.025
negative regulation of endopeptidase activity GO:0010951 84 0.025
regulation of nucleoside metabolic process GO:0009118 209 0.025
regulation of purine nucleotide metabolic process GO:1900542 264 0.025
cellular response to insulin stimulus GO:0032869 41 0.025
positive regulation of cell proliferation involved in kidney development GO:1901724 1 0.025
stress activated protein kinase signaling cascade GO:0031098 94 0.025
midbrain development GO:0030901 45 0.025
fatty acid metabolic process GO:0006631 115 0.025
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.024
response to monosaccharide GO:0034284 20 0.024
negative regulation of synaptic transmission GO:0050805 2 0.024
nuclear division GO:0000280 128 0.024
forebrain neuron development GO:0021884 2 0.024
regulation of chromosome organization GO:0033044 103 0.024
negative regulation of peptidase activity GO:0010466 91 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.024
positive regulation of metanephros development GO:0072216 3 0.024
positive regulation of fibroblast proliferation GO:0048146 21 0.024
cytoplasmic transport GO:0016482 379 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
response to oxidative stress GO:0006979 121 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.024
positive regulation of mapk cascade GO:0043410 190 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
sensory organ development GO:0007423 52 0.024
regulation of response to external stimulus GO:0032101 222 0.024
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
internal protein amino acid acetylation GO:0006475 101 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
regulation of protein catabolic process GO:0042176 155 0.023
head development GO:0060322 108 0.023
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
blood circulation GO:0008015 113 0.023
hematopoietic stem cell differentiation GO:0060218 4 0.023
oogenesis GO:0048477 2 0.023
regulation of mitochondrion organization GO:0010821 54 0.023
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.023
negative regulation of gliogenesis GO:0014014 3 0.022
regulation of cellular protein catabolic process GO:1903362 96 0.022
compound eye development GO:0048749 1 0.022
oocyte differentiation GO:0009994 2 0.022
positive regulation of epithelial cell proliferation GO:0050679 65 0.022
action potential GO:0001508 34 0.022
ureteric bud morphogenesis GO:0060675 10 0.022
heart morphogenesis GO:0003007 48 0.022
smooth muscle cell differentiation GO:0051145 8 0.022
blood vessel remodeling GO:0001974 2 0.022
meiotic chromosome segregation GO:0045132 4 0.022
negative regulation of protein ubiquitination GO:0031397 35 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
cellular response to unfolded protein GO:0034620 16 0.021
developmental process involved in reproduction GO:0003006 66 0.021
regulation of leukocyte activation GO:0002694 115 0.021
cytokine secretion GO:0050663 64 0.021
regulation of homeostatic process GO:0032844 121 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.021
reactive nitrogen species metabolic process GO:2001057 3 0.021
endothelial cell apoptotic process GO:0072577 26 0.021
maintenance of location GO:0051235 112 0.021
positive regulation of ion transmembrane transport GO:0034767 40 0.021
positive regulation of cellular protein catabolic process GO:1903364 37 0.021
negative regulation of lipid metabolic process GO:0045833 38 0.021
regulation of peptidyl tyrosine autophosphorylation GO:1900084 1 0.021
regulation of glomerular mesangial cell proliferation GO:0072124 3 0.020
protein sumoylation GO:0016925 25 0.020
retinal ganglion cell axon guidance GO:0031290 2 0.020
eye photoreceptor cell differentiation GO:0001754 2 0.020
developmental programmed cell death GO:0010623 3 0.020
regulation of neurogenesis GO:0050767 82 0.020
signal release GO:0023061 70 0.020
response to calcium ion GO:0051592 46 0.020
positive regulation of nervous system development GO:0051962 54 0.020
calcium ion import GO:0070509 23 0.020
regulation of defense response GO:0031347 154 0.020
internal peptidyl lysine acetylation GO:0018393 97 0.020
mitotic cell cycle checkpoint GO:0007093 68 0.020
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.019
endothelial cell proliferation GO:0001935 65 0.019
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.019
cranial nerve morphogenesis GO:0021602 1 0.019
glycerolipid biosynthetic process GO:0045017 51 0.019
regulation of binding GO:0051098 111 0.019
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.019
divalent metal ion transport GO:0070838 152 0.019
negative regulation of chromosome organization GO:2001251 48 0.018
nephron tubule morphogenesis GO:0072078 13 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
regulation of chromatin modification GO:1903308 51 0.018
positive regulation of proteolysis GO:0045862 142 0.018
endothelial cell chemotaxis GO:0035767 13 0.018
dna integrity checkpoint GO:0031570 71 0.018
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.018
receptor mediated endocytosis GO:0006898 84 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
negative regulation of growth GO:0045926 97 0.018
carbohydrate transport GO:0008643 37 0.018
regulation of endothelial cell differentiation GO:0045601 4 0.018
nucleoside catabolic process GO:0009164 408 0.018
regulation of membrane permeability GO:0090559 25 0.018
regulation of glucose metabolic process GO:0010906 28 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.018
regulation of neuron differentiation GO:0045664 70 0.017
cellular response to oxidative stress GO:0034599 85 0.017
sodium ion transport GO:0006814 61 0.017
regulation of protein complex assembly GO:0043254 147 0.017
cell activation GO:0001775 213 0.017
regulation of epithelial cell differentiation GO:0030856 24 0.017
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.017
homeostasis of number of cells GO:0048872 40 0.017
positive regulation of vasculogenesis GO:2001214 1 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.017
neurological system process GO:0050877 163 0.017
regulation of fibroblast proliferation GO:0048145 32 0.017
response to lipid GO:0033993 206 0.017

BHLHE40 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.073
disease of cellular proliferation DOID:14566 174 0.073
organ system cancer DOID:0050686 164 0.044
nervous system disease DOID:863 431 0.037
neuropathy DOID:870 52 0.037
charcot marie tooth disease type 4 DOID:0050541 11 0.029
neuromuscular disease DOID:440 38 0.029
charcot marie tooth disease DOID:10595 33 0.029
disease of metabolism DOID:0014667 295 0.029