Homo sapiens

76 known processes

UBE2O

ubiquitin-conjugating enzyme E2O

(Aliases: FLJ12878,E2-230K,KIAA1734)

UBE2O biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.112
protein catabolic process GO:0030163 325 0.104
protein maturation GO:0051604 233 0.099
post embryonic development GO:0009791 2 0.095
cellular macromolecule catabolic process GO:0044265 380 0.094
protein deubiquitination GO:0016579 79 0.087
chromatin organization GO:0006325 351 0.071
regulation of proteolysis GO:0030162 293 0.070
negative regulation of protein metabolic process GO:0051248 391 0.069
cellular protein catabolic process GO:0044257 261 0.065
protein processing GO:0016485 226 0.060
chromatin modification GO:0016568 298 0.059
negative regulation of protein processing GO:0010955 142 0.057
regulation of cellular amino acid metabolic process GO:0006521 6 0.055
protein modification by small protein removal GO:0070646 92 0.054
cellular amino acid metabolic process GO:0006520 116 0.052
regulation of cell differentiation GO:0045595 393 0.051
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.048
regulation of proteasomal protein catabolic process GO:0061136 87 0.048
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
amine metabolic process GO:0009308 44 0.047
cellular amine metabolic process GO:0044106 41 0.045
negative regulation of protein maturation GO:1903318 142 0.044
multicellular organismal aging GO:0010259 3 0.044
regulation of cellular protein catabolic process GO:1903362 96 0.043
protein ubiquitination GO:0016567 314 0.042
ras protein signal transduction GO:0007265 73 0.042
regulation of cell growth GO:0001558 135 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.041
regulation of protein catabolic process GO:0042176 155 0.041
regulation of cellular amine metabolic process GO:0033238 11 0.041
negative regulation of hydrolase activity GO:0051346 182 0.040
negative regulation of multicellular organismal process GO:0051241 317 0.037
histone modification GO:0016570 251 0.037
protein modification by small protein conjugation GO:0032446 342 0.036
small gtpase mediated signal transduction GO:0007264 78 0.036
regulation of endopeptidase activity GO:0052548 170 0.036
regulation of protein processing GO:0070613 150 0.035
determination of adult lifespan GO:0008340 2 0.035
negative regulation of gliogenesis GO:0014014 3 0.035
negative regulation of proteolysis GO:0045861 132 0.034
cellular ketone metabolic process GO:0042180 80 0.034
cytoplasmic transport GO:0016482 379 0.033
negative regulation of catalytic activity GO:0043086 335 0.033
female gamete generation GO:0007292 2 0.033
regulation of growth GO:0040008 165 0.033
proteasomal protein catabolic process GO:0010498 176 0.032
regulation of protein maturation GO:1903317 150 0.032
covalent chromatin modification GO:0016569 254 0.032
neuromuscular junction development GO:0007528 3 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
growth GO:0040007 202 0.030
positive regulation of catabolic process GO:0009896 310 0.030
interspecies interaction between organisms GO:0044419 156 0.030
regulation of cellular ketone metabolic process GO:0010565 50 0.030
ribonucleoside triphosphate metabolic process GO:0009199 412 0.030
negative regulation of phosphate metabolic process GO:0045936 267 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.029
positive regulation of cellular component organization GO:0051130 376 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.029
immune response GO:0006955 307 0.029
cell growth GO:0016049 160 0.029
negative regulation of endopeptidase activity GO:0010951 84 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
ribonucleoside catabolic process GO:0042454 406 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
nucleoside phosphate catabolic process GO:1901292 412 0.028
regulation of protein localization GO:0032880 296 0.028
regulation of cell cycle GO:0051726 393 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
positive regulation of cellular catabolic process GO:0031331 284 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
single organism cellular localization GO:1902580 332 0.027
locomotory behavior GO:0007626 1 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
purine nucleoside catabolic process GO:0006152 398 0.026
positive regulation of developmental process GO:0051094 314 0.026
nucleoside catabolic process GO:0009164 408 0.026
response to oxygen containing compound GO:1901700 369 0.025
organophosphate catabolic process GO:0046434 430 0.025
oogenesis GO:0048477 2 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
regulation of transferase activity GO:0051338 355 0.024
nucleotide catabolic process GO:0009166 408 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
apoptotic signaling pathway GO:0097190 268 0.024
regulation of cellular response to stress GO:0080135 244 0.024
mitotic cell cycle GO:0000278 326 0.024
viral process GO:0016032 146 0.024
cellular protein complex assembly GO:0043623 188 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
negative regulation of peptidase activity GO:0010466 91 0.023
multi organism cellular process GO:0044764 156 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
actin filament based process GO:0030029 224 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
regulation of establishment of protein localization GO:0070201 242 0.023
cell development GO:0048468 328 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
neuroblast proliferation GO:0007405 4 0.023
regulation of kinase activity GO:0043549 314 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
negative regulation of protein modification process GO:0031400 200 0.022
purine containing compound catabolic process GO:0072523 411 0.022
spermatid differentiation GO:0048515 4 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
dephosphorylation GO:0016311 209 0.022
negative regulation of cell death GO:0060548 345 0.022
blastoderm segmentation GO:0007350 2 0.022
cell fate determination GO:0001709 3 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
posttranscriptional regulation of gene expression GO:0010608 213 0.022
system process GO:0003008 349 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
positive regulation of cell differentiation GO:0045597 211 0.021
vesicle mediated transport GO:0016192 371 0.020
lipid metabolic process GO:0006629 381 0.020
adult locomotory behavior GO:0008344 1 0.020
regulation of protein kinase activity GO:0045859 289 0.020
negative regulation of developmental process GO:0051093 247 0.020
mapk cascade GO:0000165 288 0.020
response to abiotic stimulus GO:0009628 336 0.020
nucleocytoplasmic transport GO:0006913 176 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
cytokine production GO:0001816 247 0.019
cell projection organization GO:0030030 252 0.019
spermatid development GO:0007286 4 0.019
response to biotic stimulus GO:0009607 276 0.019
segmentation GO:0035282 4 0.019
nervous system development GO:0007399 293 0.019
regulation of protein transport GO:0051223 213 0.019
regulation of cellular component biogenesis GO:0044087 281 0.019
secretion GO:0046903 254 0.019
positive regulation of transport GO:0051050 336 0.019
positive regulation of immune system process GO:0002684 283 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.018
response to organic cyclic compound GO:0014070 204 0.018
negative regulation of glial cell proliferation GO:0060253 2 0.018
memory GO:0007613 3 0.018
anterior posterior axis specification GO:0009948 2 0.018
negative regulation of cell cycle GO:0045786 193 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
mitotic cell cycle process GO:1903047 286 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.018
protein autoubiquitination GO:0051865 37 0.018
oocyte development GO:0048599 1 0.018
methylation GO:0032259 106 0.018
ribonucleotide catabolic process GO:0009261 405 0.018
cation transport GO:0006812 331 0.018
regeneration GO:0031099 4 0.018
purine ribonucleotide catabolic process GO:0009154 404 0.017
positive regulation of nucleotide metabolic process GO:0045981 230 0.017
rho protein signal transduction GO:0007266 26 0.017
response to other organism GO:0051707 261 0.017
regulation of response to external stimulus GO:0032101 222 0.017
protein polyubiquitination GO:0000209 110 0.017
transmembrane transport GO:0055085 399 0.017
biological adhesion GO:0022610 331 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
positive regulation of cell death GO:0010942 263 0.017
microtubule based process GO:0007017 210 0.017
gtp catabolic process GO:0006184 237 0.017
negative regulation of apoptotic process GO:0043066 316 0.017
midgut development GO:0007494 1 0.017
regulation of gtpase activity GO:0043087 180 0.017
regulation of protein stability GO:0031647 87 0.017
carbohydrate metabolic process GO:0005975 207 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.016
gtp metabolic process GO:0046039 239 0.016
secretion by cell GO:0032940 226 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
monoubiquitinated protein deubiquitination GO:0035520 6 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
histone deubiquitination GO:0016578 16 0.016
response to external biotic stimulus GO:0043207 261 0.016
actin cytoskeleton organization GO:0030036 207 0.016
cell morphogenesis GO:0000902 296 0.016
regulation of intracellular transport GO:0032386 195 0.016
cellular lipid metabolic process GO:0044255 303 0.016
endocytosis GO:0006897 159 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
cell adhesion GO:0007155 325 0.016
regulation of glial cell proliferation GO:0060251 4 0.016
cellular component morphogenesis GO:0032989 314 0.016
nitrogen compound transport GO:0071705 191 0.016
negative regulation of transport GO:0051051 176 0.016
regulation of secretion GO:0051046 194 0.016
transmission of nerve impulse GO:0019226 11 0.016
ion transmembrane transport GO:0034220 338 0.016
regulation of cytokine production GO:0001817 232 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
positive regulation of organelle organization GO:0010638 195 0.015
t cell differentiation in thymus GO:0033077 4 0.015
membrane organization GO:0061024 292 0.015
metal ion transport GO:0030001 272 0.015
innate immune response GO:0045087 178 0.015
wnt signaling pathway GO:0016055 156 0.015
neurological system process GO:0050877 163 0.015
positive regulation of transferase activity GO:0051347 227 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
regulation of protein complex assembly GO:0043254 147 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
positive regulation of proteolysis GO:0045862 142 0.014
oocyte differentiation GO:0009994 2 0.014
regulation of secretion by cell GO:1903530 177 0.014
negative regulation of cellular component organization GO:0051129 235 0.014
endosomal transport GO:0016197 129 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
generation of neurons GO:0048699 152 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
intracellular protein transport GO:0006886 270 0.014
protein localization to organelle GO:0033365 280 0.014
negative regulation of transferase activity GO:0051348 124 0.014
regulation of mapk cascade GO:0043408 262 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
regulation of cell development GO:0060284 161 0.014
neurotransmitter secretion GO:0007269 4 0.014
hindbrain development GO:0030902 3 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
embryonic epithelial tube formation GO:0001838 4 0.014
macromolecule methylation GO:0043414 97 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
defense response GO:0006952 315 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
retinal ganglion cell axon guidance GO:0031290 2 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
positive regulation of gtpase activity GO:0043547 166 0.014
neurogenesis GO:0022008 169 0.013
regulation of immune response GO:0050776 201 0.013
nuclear transport GO:0051169 179 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
cell projection morphogenesis GO:0048858 129 0.013
tripartite regional subdivision GO:0007351 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
rna processing GO:0006396 255 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
response to cytokine GO:0034097 232 0.013
stem cell division GO:0017145 2 0.013
positive regulation of kinase activity GO:0033674 204 0.013
single organism membrane organization GO:0044802 268 0.013
modification dependent macromolecule catabolic process GO:0043632 212 0.013
positive regulation of immune response GO:0050778 159 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
regulation of cytoskeleton organization GO:0051493 177 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.013
protein stabilization GO:0050821 64 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
regulation of gtp catabolic process GO:0033124 180 0.013
mrna metabolic process GO:0016071 175 0.013
regulation of locomotion GO:0040012 329 0.013
organelle assembly GO:0070925 176 0.013
ion homeostasis GO:0050801 230 0.013
regulation of nervous system development GO:0051960 88 0.013
cellular homeostasis GO:0019725 196 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
maintenance of location GO:0051235 112 0.013
protein acylation GO:0043543 138 0.013
regulation of neurogenesis GO:0050767 82 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
positive regulation of protein transport GO:0051222 135 0.012
protein oligomerization GO:0051259 173 0.012
compound eye development GO:0048749 1 0.012
intracellular mrna localization GO:0008298 1 0.012
cell part morphogenesis GO:0032990 137 0.012
associative learning GO:0008306 1 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
atp metabolic process GO:0046034 176 0.012
inner ear morphogenesis GO:0042472 4 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
carbohydrate derivative biosynthetic process GO:1901137 207 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
regulation of membrane potential GO:0042391 95 0.012
protein autophosphorylation GO:0046777 123 0.012
regulation of neural precursor cell proliferation GO:2000177 4 0.012
microtubule cytoskeleton organization GO:0000226 176 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
regulation of system process GO:0044057 101 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
negative regulation of growth GO:0045926 97 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
peptidyl lysine modification GO:0018205 144 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
oxidation reduction process GO:0055114 396 0.012
monoubiquitinated histone h2a deubiquitination GO:0035522 3 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
anatomical structure homeostasis GO:0060249 100 0.012
cellular component disassembly GO:0022411 92 0.012
circadian behavior GO:0048512 2 0.011
metencephalon development GO:0022037 2 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
negative regulation of protein transport GO:0051224 75 0.011
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.011
circulatory system development GO:0072359 262 0.011
regulation of peptidase activity GO:0052547 180 0.011
histone acetylation GO:0016573 93 0.011
cation transmembrane transport GO:0098655 238 0.011
cardiac muscle cell contraction GO:0086003 4 0.011
anion transport GO:0006820 161 0.011
epithelium development GO:0060429 227 0.011
response to oxidative stress GO:0006979 121 0.011
motor neuron axon guidance GO:0008045 2 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
endomembrane system organization GO:0010256 196 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.011
immune response regulating signaling pathway GO:0002764 97 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
single organism cell adhesion GO:0098602 179 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
regulation of neuroblast proliferation GO:1902692 3 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
chemical homeostasis GO:0048878 306 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
internal protein amino acid acetylation GO:0006475 101 0.011
epidermis morphogenesis GO:0048730 3 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.011
rhythmic behavior GO:0007622 2 0.011
regulation of actin filament based process GO:0032970 141 0.011
negative regulation of cell growth GO:0030308 83 0.011
rna interference GO:0016246 4 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
cell cycle phase transition GO:0044770 173 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
regulation of dephosphorylation GO:0035303 96 0.011
limbic system development GO:0021761 3 0.011
hindlimb morphogenesis GO:0035137 2 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
organ formation GO:0048645 3 0.011
tissue regeneration GO:0042246 3 0.011
activation of immune response GO:0002253 114 0.011
response to lipid GO:0033993 206 0.011
forebrain generation of neurons GO:0021872 3 0.011
sex determination GO:0007530 3 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
regulation of cellular component movement GO:0051270 334 0.011
single organism nuclear import GO:1902593 104 0.011
sleep GO:0030431 2 0.011
viral life cycle GO:0019058 132 0.011
meiotic chromosome segregation GO:0045132 4 0.011
regulation of cell migration GO:0030334 289 0.010
nuclear import GO:0051170 106 0.010
regulation of cell adhesion GO:0030155 166 0.010
mating GO:0007618 1 0.010
reproductive process GO:0022414 106 0.010
immune system development GO:0002520 195 0.010
negative regulation of catabolic process GO:0009895 104 0.010
peptidyl tyrosine modification GO:0018212 170 0.010
myeloid cell differentiation GO:0030099 117 0.010
regulation of cell motility GO:2000145 299 0.010
neural tube formation GO:0001841 3 0.010
immune response activating signal transduction GO:0002757 90 0.010
primary neural tube formation GO:0014020 3 0.010
immune effector process GO:0002252 159 0.010
positive regulation of cell proliferation GO:0008284 301 0.010
protein k48 linked deubiquitination GO:0071108 19 0.010
leukocyte activation GO:0045321 164 0.010
internal peptidyl lysine acetylation GO:0018393 97 0.010
peptidyl serine modification GO:0018209 106 0.010
cellular response to nutrient levels GO:0031669 69 0.010
reactive nitrogen species metabolic process GO:2001057 3 0.010
tube closure GO:0060606 3 0.010
sequestering of metal ion GO:0051238 24 0.010
sensory perception of smell GO:0007608 2 0.010
somitogenesis GO:0001756 2 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
salivary gland morphogenesis GO:0007435 4 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
action potential GO:0001508 34 0.010
dna repair GO:0006281 198 0.010
blastocyst development GO:0001824 3 0.010
neuron projection development GO:0031175 106 0.010
negative regulation of organelle organization GO:0010639 126 0.010
single organismal cell cell adhesion GO:0016337 148 0.010
cell substrate adhesion GO:0031589 132 0.010
cerebellum development GO:0021549 2 0.010

UBE2O disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.027
cardiovascular system disease DOID:1287 106 0.022
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
disease of metabolism DOID:0014667 295 0.017
organ system cancer DOID:0050686 164 0.017
inherited metabolic disorder DOID:655 242 0.016
central nervous system disease DOID:331 186 0.016
muscular disease DOID:0080000 114 0.015
muscle tissue disease DOID:66 113 0.015
eye and adnexa disease DOID:1492 150 0.015
heart disease DOID:114 68 0.013
eye disease DOID:5614 149 0.011
brain disease DOID:936 73 0.011
connective tissue disease DOID:65 109 0.011