Homo sapiens

32 known processes

METTL1

methyltransferase like 1

(Aliases: YDL201w,C12orf1,TRM8,FLJ95748)

METTL1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trna processing GO:0008033 23 0.898
rna processing GO:0006396 255 0.848
ncrna metabolic process GO:0034660 108 0.687
rna modification GO:0009451 27 0.674
trna methylation GO:0030488 7 0.630
macromolecule methylation GO:0043414 97 0.606
oogenesis GO:0048477 2 0.553
ncrna processing GO:0034470 83 0.481
female gamete generation GO:0007292 2 0.427
methylation GO:0032259 106 0.365
trna metabolic process GO:0006399 35 0.266
post embryonic development GO:0009791 2 0.183
single organism reproductive process GO:0044702 98 0.177
mitochondrion organization GO:0007005 156 0.139
cell development GO:0048468 328 0.083
negative regulation of catalytic activity GO:0043086 335 0.082
ribonucleoprotein complex subunit organization GO:0071826 81 0.080
cellular macromolecular complex assembly GO:0034622 324 0.072
reproductive process GO:0022414 106 0.069
protein localization to organelle GO:0033365 280 0.059
cytoplasmic transport GO:0016482 379 0.058
ribonucleoprotein complex assembly GO:0022618 78 0.052
protein import GO:0017038 130 0.046
single organism carbohydrate metabolic process GO:0044723 193 0.045
blastocyst development GO:0001824 3 0.044
intracellular protein transport GO:0006886 270 0.044
blastocyst formation GO:0001825 3 0.043
organelle assembly GO:0070925 176 0.042
cellular ketone metabolic process GO:0042180 80 0.041
response to oxygen containing compound GO:1901700 369 0.041
protein targeting GO:0006605 187 0.038
vesicle mediated transport GO:0016192 371 0.037
cellular amino acid metabolic process GO:0006520 116 0.035
lipid metabolic process GO:0006629 381 0.035
developmental process involved in reproduction GO:0003006 66 0.035
multicellular organism reproduction GO:0032504 42 0.033
defense response GO:0006952 315 0.033
negative regulation of cell death GO:0060548 345 0.032
establishment of protein localization to organelle GO:0072594 172 0.032
multicellular organismal reproductive process GO:0048609 40 0.032
maturation of ssu rrna GO:0030490 3 0.032
cellular response to oxygen containing compound GO:1901701 276 0.030
response to other organism GO:0051707 261 0.030
rrna metabolic process GO:0016072 40 0.030
response to biotic stimulus GO:0009607 276 0.029
apoptotic signaling pathway GO:0097190 268 0.029
amine metabolic process GO:0009308 44 0.029
negative regulation of apoptotic process GO:0043066 316 0.029
protein maturation GO:0051604 233 0.028
endocytosis GO:0006897 159 0.028
negative regulation of peptidase activity GO:0010466 91 0.028
regulation of cellular response to stress GO:0080135 244 0.028
establishment of protein localization to mitochondrion GO:0072655 22 0.028
carbohydrate derivative biosynthetic process GO:1901137 207 0.028
maturation of lsu rrna GO:0000470 3 0.027
single organism membrane organization GO:0044802 268 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
regulation of proteolysis GO:0030162 293 0.025
negative regulation of cell proliferation GO:0008285 228 0.025
mitotic cell cycle GO:0000278 326 0.025
single organism cellular localization GO:1902580 332 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.024
nervous system development GO:0007399 293 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
rna interference GO:0016246 4 0.024
regulation of protein processing GO:0070613 150 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.023
small molecule biosynthetic process GO:0044283 157 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
regulation of establishment of protein localization GO:0070201 242 0.022
cell growth GO:0016049 160 0.022
memory GO:0007613 3 0.022
negative regulation of programmed cell death GO:0043069 321 0.022
multi organism reproductive process GO:0044703 54 0.022
cellular response to dna damage stimulus GO:0006974 379 0.022
nucleocytoplasmic transport GO:0006913 176 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
positive regulation of cellular amine metabolic process GO:0033240 7 0.021
regulation of endopeptidase activity GO:0052548 170 0.021
maintenance of location GO:0051235 112 0.021
neurogenesis GO:0022008 169 0.021
embryo development GO:0009790 123 0.021
negative regulation of phosphate metabolic process GO:0045936 267 0.021
positive regulation of transport GO:0051050 336 0.021
ribonucleoside triphosphate metabolic process GO:0009199 412 0.021
regulation of cell differentiation GO:0045595 393 0.020
cellular response to organic cyclic compound GO:0071407 127 0.020
regulation of protein maturation GO:1903317 150 0.020
negative regulation of immune system process GO:0002683 136 0.020
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
neuromuscular junction development GO:0007528 3 0.020
reproduction GO:0000003 63 0.020
regulation of immune response GO:0050776 201 0.020
growth GO:0040007 202 0.020
immune response GO:0006955 307 0.019
carbohydrate metabolic process GO:0005975 207 0.019
membrane organization GO:0061024 292 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
response to organic cyclic compound GO:0014070 204 0.018
regulation of transferase activity GO:0051338 355 0.018
response to abiotic stimulus GO:0009628 336 0.018
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.018
spermatid differentiation GO:0048515 4 0.018
protein ubiquitination GO:0016567 314 0.018
segmentation GO:0035282 4 0.018
cellular lipid metabolic process GO:0044255 303 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
transmembrane transport GO:0055085 399 0.018
protein localization to membrane GO:0072657 160 0.017
secretion GO:0046903 254 0.017
purine containing compound catabolic process GO:0072523 411 0.017
regeneration GO:0031099 4 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
ribonucleoprotein complex biogenesis GO:0022613 116 0.017
cellular amine metabolic process GO:0044106 41 0.017
multicellular organismal aging GO:0010259 3 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
negative regulation of protein maturation GO:1903318 142 0.016
response to external biotic stimulus GO:0043207 261 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
regulation of defense response GO:0031347 154 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
protein modification by small protein conjugation GO:0032446 342 0.016
organophosphate catabolic process GO:0046434 430 0.016
protein catabolic process GO:0030163 325 0.016
regulation of protein transport GO:0051223 213 0.016
trophectodermal cell differentiation GO:0001829 3 0.016
negative regulation of cell cycle GO:0045786 193 0.016
organophosphate biosynthetic process GO:0090407 163 0.015
regulation of kinase activity GO:0043549 314 0.015
nuclear transport GO:0051169 179 0.015
protein oligomerization GO:0051259 173 0.015
sexual reproduction GO:0019953 37 0.015
cellular homeostasis GO:0019725 196 0.015
canonical wnt signaling pathway GO:0060070 116 0.015
regulation of protein localization GO:0032880 296 0.015
system process GO:0003008 349 0.015
actin filament based process GO:0030029 224 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
cellular response to endogenous stimulus GO:0071495 336 0.014
t cell differentiation in thymus GO:0033077 4 0.014
vitamin k biosynthetic process GO:0042371 2 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
regulation of protein kinase activity GO:0045859 289 0.014
cell cycle arrest GO:0007050 71 0.014
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 3 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
protein localization to mitochondrion GO:0070585 25 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
receptor mediated endocytosis GO:0006898 84 0.014
cell morphogenesis GO:0000902 296 0.014
positive regulation of developmental process GO:0051094 314 0.014
negative regulation of protein processing GO:0010955 142 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
positive regulation of hydrolase activity GO:0051345 331 0.013
immune effector process GO:0002252 159 0.013
negative regulation of endopeptidase activity GO:0010951 84 0.013
oxidation reduction process GO:0055114 396 0.013
negative regulation of protein modification process GO:0031400 200 0.013
regulation of growth GO:0040008 165 0.013
cell projection assembly GO:0030031 126 0.013
nucleotide catabolic process GO:0009166 408 0.013
innate immune response GO:0045087 178 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
negative regulation of proteolysis GO:0045861 132 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.012
cellular component morphogenesis GO:0032989 314 0.012
response to bacterium GO:0009617 144 0.012
secretion by cell GO:0032940 226 0.012
tripartite regional subdivision GO:0007351 2 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.012
nuclear import GO:0051170 106 0.012
negative regulation of organelle organization GO:0010639 126 0.012
regulation of intracellular transport GO:0032386 195 0.012
negative regulation of transferase activity GO:0051348 124 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
mitotic cell cycle process GO:1903047 286 0.012
regulation of cell growth GO:0001558 135 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.012
ribosome biogenesis GO:0042254 48 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
cell projection organization GO:0030030 252 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
regulation of peptidase activity GO:0052547 180 0.012
tube development GO:0035295 125 0.012
regulation of cell cycle GO:0051726 393 0.012
negative regulation of developmental process GO:0051093 247 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
protein import into nucleus GO:0006606 104 0.011
nucleoside catabolic process GO:0009164 408 0.011
regulation of anatomical structure size GO:0090066 101 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
wnt signaling pathway GO:0016055 156 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
lipid biosynthetic process GO:0008610 177 0.011
microtubule based process GO:0007017 210 0.011
regulation of protein catabolic process GO:0042176 155 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
protein targeting to nucleus GO:0044744 104 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
cell cycle phase transition GO:0044770 173 0.011
defense response to bacterium GO:0042742 63 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
lipid localization GO:0010876 106 0.011
male gamete generation GO:0048232 22 0.011
protein secretion GO:0009306 98 0.010
mitochondrial transport GO:0006839 60 0.010
compound eye development GO:0048749 1 0.010
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
glycoprotein metabolic process GO:0009100 110 0.010
circulatory system development GO:0072359 262 0.010
positive regulation of protein transport GO:0051222 135 0.010
blastoderm segmentation GO:0007350 2 0.010
positive regulation of immune system process GO:0002684 283 0.010
purine ribonucleotide catabolic process GO:0009154 404 0.010
response to hormone GO:0009725 175 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
defense response to other organism GO:0098542 129 0.010
locomotory behavior GO:0007626 1 0.010
cardiovascular system development GO:0072358 262 0.010
intrinsic apoptotic signaling pathway GO:0097193 127 0.010
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.010
glycosyl compound catabolic process GO:1901658 413 0.010

METTL1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.177
inherited metabolic disorder DOID:655 242 0.140
carbohydrate metabolic disorder DOID:2978 55 0.032
congenital disorder of glycosylation DOID:5212 26 0.032
disease of cellular proliferation DOID:14566 174 0.020
congenital disorder of glycosylation type i DOID:0050570 16 0.019
musculoskeletal system disease DOID:17 223 0.018
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
porphyria DOID:13268 8 0.014
connective tissue disease DOID:65 109 0.013
cancer DOID:162 167 0.010