Homo sapiens

97 known processes

SERPING1

serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

(Aliases: C1IN,C1INH,HAE2,C1NH,HAE1)

SERPING1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of protein activation cascade GO:2000258 7 0.993
protein activation cascade GO:0072376 22 0.838
negative regulation of complement activation GO:0045916 7 0.828
regulation of protein activation cascade GO:2000257 8 0.746
regulation of complement activation GO:0030449 8 0.450
complement activation lectin pathway GO:0001867 7 0.373
negative regulation of complement activation lectin pathway GO:0001869 2 0.333
innate immune response GO:0045087 178 0.322
complement activation GO:0006956 19 0.312
defense response GO:0006952 315 0.298
negative regulation of protein maturation GO:1903318 142 0.287
immune effector process GO:0002252 159 0.272
immune response GO:0006955 307 0.264
negative regulation of immune system process GO:0002683 136 0.264
response to cytokine GO:0034097 232 0.248
positive regulation of immune system process GO:0002684 283 0.244
humoral immune response GO:0006959 49 0.233
protein maturation GO:0051604 233 0.227
negative regulation of protein processing GO:0010955 142 0.191
negative regulation of protein metabolic process GO:0051248 391 0.191
positive regulation of immune response GO:0050778 159 0.189
negative regulation of multicellular organismal process GO:0051241 317 0.171
Human
regulation of protein processing GO:0070613 150 0.154
regulation of cell migration GO:0030334 289 0.154
cellular lipid metabolic process GO:0044255 303 0.150
negative regulation of humoral immune response GO:0002921 7 0.145
regulation of defense response GO:0031347 154 0.144
regulation of response to external stimulus GO:0032101 222 0.142
regulation of cell motility GO:2000145 299 0.138
inflammatory response GO:0006954 79 0.132
response to wounding GO:0009611 168 0.114
protein processing GO:0016485 226 0.104
regulation of complement activation lectin pathway GO:0001868 2 0.101
regulation of protein maturation GO:1903317 150 0.094
negative regulation of catalytic activity GO:0043086 335 0.092
regulation of immune response GO:0050776 201 0.085
regulation of immune effector process GO:0002697 91 0.084
cytokine production GO:0001816 247 0.082
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.079
cellular response to cytokine stimulus GO:0071345 181 0.078
lipid metabolic process GO:0006629 381 0.078
regulation of response to wounding GO:1903034 101 0.078
multi organism cellular process GO:0044764 156 0.076
positive regulation of cellular amine metabolic process GO:0033240 7 0.076
cell activation GO:0001775 213 0.074
activation of immune response GO:0002253 114 0.071
vesicle mediated transport GO:0016192 371 0.070
response to oxygen containing compound GO:1901700 369 0.069
response to organic cyclic compound GO:0014070 204 0.069
negative regulation of cell motility GO:2000146 104 0.066
interspecies interaction between organisms GO:0044419 156 0.062
response to biotic stimulus GO:0009607 276 0.061
response to external biotic stimulus GO:0043207 261 0.060
regulation of inflammatory response GO:0050727 46 0.059
acute inflammatory response GO:0002526 21 0.058
negative regulation of immune effector process GO:0002698 38 0.053
cellular amino acid metabolic process GO:0006520 116 0.053
regulation of renal albumin absorption GO:2000532 1 0.053
positive regulation of transport GO:0051050 336 0.052
negative regulation of cell proliferation GO:0008285 228 0.051
negative regulation of hydrolase activity GO:0051346 182 0.049
regulation of cellular amine metabolic process GO:0033238 11 0.047
regulation of cellular component movement GO:0051270 334 0.046
negative regulation of peptidase activity GO:0010466 91 0.046
regulation of endopeptidase activity GO:0052548 170 0.045
lipid biosynthetic process GO:0008610 177 0.044
regulation of body fluid levels GO:0050878 99 0.044
Human
cellular response to oxygen containing compound GO:1901701 276 0.044
regulation of acute inflammatory response GO:0002673 13 0.043
negative regulation of cellular component movement GO:0051271 106 0.043
wound healing GO:0042060 115 0.042
Human
regulation of macrophage chemotaxis GO:0010758 4 0.042
negative regulation of multi organism process GO:0043901 92 0.042
negative regulation of immune response GO:0050777 40 0.041
cellular ketone metabolic process GO:0042180 80 0.041
regulation of cellular ketone metabolic process GO:0010565 50 0.039
regulation of multi organism process GO:0043900 157 0.038
viral genome replication GO:0019079 50 0.038
cellular amine metabolic process GO:0044106 41 0.038
biological adhesion GO:0022610 331 0.037
regulation of cell adhesion GO:0030155 166 0.037
viral process GO:0016032 146 0.036
cytokine mediated signaling pathway GO:0019221 109 0.036
negative regulation of cell migration GO:0030336 102 0.035
positive regulation of protein kinase activity GO:0045860 190 0.035
regulation of establishment of protein localization GO:0070201 242 0.035
response to other organism GO:0051707 261 0.034
defense response to other organism GO:0098542 129 0.034
regulation of transferase activity GO:0051338 355 0.034
negative regulation of protein modification process GO:0031400 200 0.033
negative regulation of proteolysis GO:0045861 132 0.033
neurogenesis GO:0022008 169 0.033
Human
monocarboxylic acid metabolic process GO:0032787 185 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.032
amine metabolic process GO:0009308 44 0.032
purine nucleotide catabolic process GO:0006195 405 0.032
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.032
regulation of kinase activity GO:0043549 314 0.032
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
post embryonic development GO:0009791 2 0.031
positive regulation of cell death GO:0010942 263 0.031
organophosphate catabolic process GO:0046434 430 0.031
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.030
regeneration GO:0031099 4 0.030
positive regulation of transferase activity GO:0051347 227 0.030
response to interferon gamma GO:0034341 39 0.030
negative regulation of viral process GO:0048525 66 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.029
regulation of locomotion GO:0040012 329 0.029
negative regulation of response to wounding GO:1903035 47 0.029
Human
epithelium migration GO:0090132 119 0.029
regulation of cell differentiation GO:0045595 393 0.028
Human
negative regulation of locomotion GO:0040013 118 0.028
organonitrogen compound biosynthetic process GO:1901566 200 0.028
positive regulation of renal albumin absorption GO:2000534 1 0.028
response to abiotic stimulus GO:0009628 336 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
response to organophosphorus GO:0046683 41 0.027
regulation of cytokine production GO:0001817 232 0.027
Human
cellular protein catabolic process GO:0044257 261 0.027
regulation of viral process GO:0050792 103 0.027
purine nucleoside triphosphate catabolic process GO:0009146 392 0.027
viral life cycle GO:0019058 132 0.027
single organism cell adhesion GO:0098602 179 0.027
fatty acid metabolic process GO:0006631 115 0.027
coagulation GO:0050817 78 0.026
Human
organic hydroxy compound metabolic process GO:1901615 147 0.026
circulatory system development GO:0072359 262 0.025
Human
response to nitrogen compound GO:1901698 184 0.025
regulation of proteolysis GO:0030162 293 0.025
single organismal cell cell adhesion GO:0016337 148 0.024
regulation of protein kinase activity GO:0045859 289 0.024
organic acid biosynthetic process GO:0016053 97 0.024
purine containing compound catabolic process GO:0072523 411 0.024
nucleotide catabolic process GO:0009166 408 0.024
response to camp GO:0051591 25 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
Human
negative regulation of defense response GO:0031348 47 0.023
response to lipid GO:0033993 206 0.023
regulation of protein transport GO:0051223 213 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
positive regulation of cytokine production GO:0001819 167 0.023
Human
secretion GO:0046903 254 0.022
lipid transport GO:0006869 90 0.022
defense response to virus GO:0051607 71 0.022
acylglycerol metabolic process GO:0006639 27 0.022
purine nucleoside catabolic process GO:0006152 398 0.022
positive regulation of kinase activity GO:0033674 204 0.022
purine ribonucleoside metabolic process GO:0046128 437 0.022
regulation of secretion by cell GO:1903530 177 0.022
leukocyte activation GO:0045321 164 0.022
regulation of humoral immune response GO:0002920 11 0.021
regulation of viral genome replication GO:0045069 48 0.021
regulation of intracellular transport GO:0032386 195 0.021
secretion by cell GO:0032940 226 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
Human
positive regulation of cellular catabolic process GO:0031331 284 0.021
apoptotic signaling pathway GO:0097190 268 0.021
positive regulation of cellular component organization GO:0051130 376 0.021
Human
oxidation reduction process GO:0055114 396 0.021
cellular modified amino acid metabolic process GO:0006575 64 0.021
cation transport GO:0006812 331 0.021
divalent inorganic cation homeostasis GO:0072507 136 0.021
positive regulation of cell differentiation GO:0045597 211 0.020
Human
single organism carbohydrate metabolic process GO:0044723 193 0.020
cytokine secretion GO:0050663 64 0.020
carboxylic acid biosynthetic process GO:0046394 97 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
protein oligomerization GO:0051259 173 0.020
small molecule biosynthetic process GO:0044283 157 0.020
positive regulation of developmental process GO:0051094 314 0.020
Human
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
glycerolipid metabolic process GO:0046486 107 0.019
positive regulation of catabolic process GO:0009896 310 0.019
negative regulation of response to external stimulus GO:0032102 83 0.019
Human
nucleoside catabolic process GO:0009164 408 0.019
cell adhesion GO:0007155 325 0.019
positive regulation of cell proliferation GO:0008284 301 0.019
cell chemotaxis GO:0060326 112 0.019
negative regulation of cell death GO:0060548 345 0.019
negative regulation of viral genome replication GO:0045071 35 0.019
regulation of hormone levels GO:0010817 125 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
regulation of cellular response to stress GO:0080135 244 0.018
Human
nuclear transport GO:0051169 179 0.018
positive regulation of lymphocyte activation GO:0051251 73 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.018
protein catabolic process GO:0030163 325 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
transmembrane transport GO:0055085 399 0.017
endocytosis GO:0006897 159 0.017
negative regulation of transport GO:0051051 176 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
response to virus GO:0009615 126 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
chemical homeostasis GO:0048878 306 0.017
g protein coupled receptor signaling pathway GO:0007186 207 0.017
lipid localization GO:0010876 106 0.017
positive regulation of secretion GO:0051047 116 0.017
cellular amide metabolic process GO:0043603 69 0.017
regulation of leukocyte migration GO:0002685 63 0.017
positive regulation of nucleoside metabolic process GO:0045979 186 0.017
negative regulation of homotypic cell cell adhesion GO:0034111 3 0.016
single organism cellular localization GO:1902580 332 0.016
blood coagulation GO:0007596 76 0.016
Human
epithelial cell migration GO:0010631 119 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
single organism membrane organization GO:0044802 268 0.016
monocarboxylic acid biosynthetic process GO:0072330 67 0.016
positive regulation of cell migration GO:0030335 172 0.016
regulation of protein catabolic process GO:0042176 155 0.016
negative regulation of platelet aggregation GO:0090331 3 0.016
regulation of peptidase activity GO:0052547 180 0.016
cholesterol transport GO:0030301 39 0.016
response to purine containing compound GO:0014074 40 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
blood vessel morphogenesis GO:0048514 162 0.015
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
female gamete generation GO:0007292 2 0.015
hemostasis GO:0007599 76 0.015
Human
small molecule catabolic process GO:0044282 92 0.015
regulation of leukocyte activation GO:0002694 115 0.015
intracellular protein transport GO:0006886 270 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
negative regulation of endopeptidase activity GO:0010951 84 0.015
determination of adult lifespan GO:0008340 2 0.015
multicellular organismal aging GO:0010259 3 0.015
membrane organization GO:0061024 292 0.015
negative regulation of blood coagulation GO:0030195 22 0.015
Human
nucleoside triphosphate metabolic process GO:0009141 422 0.015
i kappab kinase nf kappab signaling GO:0007249 166 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
renal albumin absorption GO:0097018 1 0.015
ossification GO:0001503 121 0.015
metal ion transport GO:0030001 272 0.014
cation homeostasis GO:0055080 189 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
cellular response to dna damage stimulus GO:0006974 379 0.014
entry into host GO:0044409 25 0.014
negative regulation of cytokine production GO:0001818 82 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.014
ion homeostasis GO:0050801 230 0.014
organic hydroxy compound transport GO:0015850 63 0.014
nervous system development GO:0007399 293 0.014
Human
regulation of smooth muscle cell proliferation GO:0048660 28 0.014
positive regulation of locomotion GO:0040017 186 0.014
regulation of protein localization GO:0032880 296 0.014
positive regulation of secretion by cell GO:1903532 108 0.013
positive regulation of leukocyte activation GO:0002696 80 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
Human
negative regulation of developmental process GO:0051093 247 0.013
Human
sulfur compound metabolic process GO:0006790 101 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
renal system process involved in regulation of blood volume GO:0001977 4 0.013
glucose metabolic process GO:0006006 45 0.013
sterol transport GO:0015918 39 0.013
phospholipid metabolic process GO:0006644 99 0.013
circadian behavior GO:0048512 2 0.013
system process GO:0003008 349 0.013
regulation of platelet aggregation GO:0090330 4 0.013
response to bacterium GO:0009617 144 0.013
cdc42 protein signal transduction GO:0032488 4 0.013
cellular homeostasis GO:0019725 196 0.013
negative regulation of blood pressure GO:0045776 3 0.013
regulation of endocytosis GO:0030100 72 0.012
regulation of secretion GO:0051046 194 0.012
regulation of cytokine secretion GO:0050707 57 0.012
complement activation classical pathway GO:0006958 3 0.012
positive regulation of corticosteroid hormone secretion GO:2000848 5 0.012
mapk cascade GO:0000165 288 0.012
Human
gtp metabolic process GO:0046039 239 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
cellular protein complex assembly GO:0043623 188 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
growth GO:0040007 202 0.012
neurological system process GO:0050877 163 0.012
response to axon injury GO:0048678 1 0.012
chemotaxis GO:0006935 157 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
cell development GO:0048468 328 0.012
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.012
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
peptide metabolic process GO:0006518 51 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
rhythmic behavior GO:0007622 2 0.012
cellular cation homeostasis GO:0030003 163 0.012
cardiovascular system development GO:0072358 262 0.012
Human
t cell activation GO:0042110 99 0.012
regulation of tumor necrosis factor production GO:0032680 43 0.012
oogenesis GO:0048477 2 0.012
organ morphogenesis GO:0009887 147 0.011
maintenance of location GO:0051235 112 0.011
interaction with host GO:0051701 42 0.011
regulation of blood coagulation GO:0030193 42 0.011
Human
gtp catabolic process GO:0006184 237 0.011
cell morphogenesis GO:0000902 296 0.011
response to hormone GO:0009725 175 0.011
negative regulation of macrophage differentiation GO:0045650 2 0.011
negative regulation of catabolic process GO:0009895 104 0.011
regulation of mapk cascade GO:0043408 262 0.011
Human
embryo development GO:0009790 123 0.011
multi organism metabolic process GO:0044033 41 0.011
regulation of viral entry into host cell GO:0046596 17 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
negative regulation of leukocyte differentiation GO:1902106 24 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
hindbrain development GO:0030902 3 0.011
endothelial cell proliferation GO:0001935 65 0.011
lymphocyte activation GO:0046649 133 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
vasculature development GO:0001944 181 0.011
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.011
negative regulation of response to cytokine stimulus GO:0060761 25 0.011
negative regulation of synaptic transmission GO:0050805 2 0.011
response to organonitrogen compound GO:0010243 156 0.011
protein modification by small protein conjugation GO:0032446 342 0.011
spermatid differentiation GO:0048515 4 0.011
cytoplasmic transport GO:0016482 379 0.011
response to inorganic substance GO:0010035 127 0.011
locomotory behavior GO:0007626 1 0.011
cellular carbohydrate metabolic process GO:0044262 84 0.011
ras protein signal transduction GO:0007265 73 0.011
lipopolysaccharide transport GO:0015920 2 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
rho protein signal transduction GO:0007266 26 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
positive regulation of protein transport GO:0051222 135 0.011
regulation of cell activation GO:0050865 125 0.011
immune system development GO:0002520 195 0.011
inorganic anion transmembrane transport GO:0098661 47 0.011
metal ion homeostasis GO:0055065 169 0.010
positive regulation of cell motility GO:2000147 177 0.010
epithelial cell differentiation GO:0030855 141 0.010
plasma membrane organization GO:0007009 115 0.010
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.010
purine nucleoside monophosphate catabolic process GO:0009128 158 0.010
carbohydrate metabolic process GO:0005975 207 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
platelet activation GO:0030168 44 0.010
endothelial cell migration GO:0043542 86 0.010
cellular response to biotic stimulus GO:0071216 71 0.010

SERPING1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.094
hemolytic anemia DOID:583 20 0.055
hemolytic uremic syndrome DOID:12554 8 0.055
normocytic anemia DOID:720 20 0.055
anemia DOID:2355 55 0.055
hematopoietic system disease DOID:74 100 0.055
disease of metabolism DOID:0014667 295 0.037
sensory system disease DOID:0050155 203 0.035
nervous system disease DOID:863 431 0.035
eye and adnexa disease DOID:1492 150 0.030
inherited metabolic disorder DOID:655 242 0.018
eye disease DOID:5614 149 0.014
central nervous system disease DOID:331 186 0.013
neurodegenerative disease DOID:1289 102 0.012
integumentary system disease DOID:16 43 0.004
skin disease DOID:37 33 0.002