|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.665
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.550
|
|
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.513
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.508
|
Yeast |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.429
|
Yeast |
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.427
|
|
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.416
|
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.402
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.374
|
|
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.358
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.353
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.349
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.333
|
Yeast |
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.325
|
|
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.277
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.228
|
Mouse |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.227
|
Worm |
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.223
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.222
|
|
|
|
acetyl coa metabolic process
|
GO:0006084 |
8 |
0.220
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.215
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.201
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.198
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.196
|
Yeast |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.192
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.185
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.184
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.179
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.160
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.152
|
|
|
|
regulation of fatty acid biosynthetic process
|
GO:0042304 |
9 |
0.152
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.149
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.148
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.139
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.136
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.136
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.134
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.133
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.132
|
|
|
|
phagosome lysosome fusion
|
GO:0090385 |
4 |
0.129
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.125
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.124
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.118
|
Yeast |
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.116
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.112
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.111
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.108
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.106
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.102
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.101
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.099
|
Human |
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.097
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.096
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.095
|
|
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.094
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.092
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.092
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.092
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.091
|
Worm |
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.091
|
Yeast |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.088
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.087
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.086
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.086
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.085
|
|
|
|
regulation of protein deubiquitination
|
GO:0090085 |
4 |
0.083
|
|
|
|
dolichol metabolic process
|
GO:0019348 |
3 |
0.081
|
|
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
5 |
0.080
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.079
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.078
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.076
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.075
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.074
|
|
|
|
hypoxia inducible factor 1alpha signaling pathway
|
GO:0097411 |
3 |
0.074
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.074
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.073
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.073
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.073
|
Human |
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.072
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.071
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.071
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.070
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
4 |
0.070
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.070
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.069
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.069
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.068
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.067
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
24 |
0.065
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.064
|
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.064
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.064
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.063
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.062
|
|
|
|
regulation of coenzyme metabolic process
|
GO:0051196 |
3 |
0.062
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.061
|
|
|
|
positive regulation of t cell tolerance induction
|
GO:0002666 |
2 |
0.059
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.059
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.059
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.059
|
Yeast |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.058
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.058
|
Yeast |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.058
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.057
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.056
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.056
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.056
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.055
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.055
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.054
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.054
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.054
|
Yeast |
|
|
macropinocytosis
|
GO:0044351 |
1 |
0.052
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.051
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.051
|
Worm |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.051
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.050
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.049
|
|
|
|
progesterone receptor signaling pathway
|
GO:0050847 |
3 |
0.049
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.049
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.049
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.049
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.048
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.048
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.048
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.048
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.048
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.048
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.047
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.047
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.047
|
Yeast |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.046
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.046
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.046
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.046
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.046
|
Human |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.045
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.045
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.045
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.045
|
|
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.045
|
|
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.045
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.044
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.044
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.044
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.044
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.043
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.043
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.043
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.042
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.042
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.042
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.042
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.042
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.042
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.042
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.042
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.041
|
Worm |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.041
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.041
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.040
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.040
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.039
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.039
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.039
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.039
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.039
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.039
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.038
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.038
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.038
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.038
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.038
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.038
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.038
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.037
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.037
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.037
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.037
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.037
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.037
|
Mouse |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.037
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.036
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.036
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.036
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.036
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.036
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.036
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.035
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.035
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.035
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.035
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.035
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.034
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.034
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.034
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.034
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.034
|
Yeast |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.034
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.034
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.034
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.034
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.034
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.033
|
|
|
|
protein homotetramerization
|
GO:0051289 |
28 |
0.033
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.033
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.033
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.033
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.033
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.033
|
Worm |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.033
|
|
|
|
regulation of acyl coa biosynthetic process
|
GO:0050812 |
2 |
0.033
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.033
|
|
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.033
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.033
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.032
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.032
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.032
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.032
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.032
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.032
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.032
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.032
|
|
|
|
regulation of multivesicular body size
|
GO:0010796 |
1 |
0.032
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.032
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.031
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.031
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.031
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.031
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.031
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.031
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.031
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.031
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.031
|
|
|
|
hexose metabolic process
|
GO:0019318 |
55 |
0.031
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.030
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.030
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.030
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.030
|
|
|
|
positive regulation of protein localization to cell surface
|
GO:2000010 |
6 |
0.030
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.030
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.030
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.030
|
Yeast |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.030
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.030
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.030
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.030
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.029
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.029
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.029
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.029
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.029
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.029
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.029
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.029
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.029
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.029
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.029
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.029
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.029
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.029
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.028
|
|
|
|
regulation of t cell tolerance induction
|
GO:0002664 |
4 |
0.028
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.028
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.028
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.028
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.028
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.028
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.028
|
Human |
|
|
pyruvate metabolic process
|
GO:0006090 |
26 |
0.028
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.027
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.027
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.027
|
|
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.027
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.027
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.027
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.027
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.027
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.027
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.027
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.027
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.026
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.026
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.026
|
Yeast |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.026
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.026
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.026
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.026
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.026
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.025
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.025
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.025
|
|
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.025
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.025
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.025
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.025
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.025
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.025
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.024
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.024
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.024
|
|
|
|
t cell tolerance induction
|
GO:0002517 |
4 |
0.024
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.024
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.024
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.024
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.024
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.024
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.024
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.024
|
Yeast |
|
|
cellular response to fatty acid
|
GO:0071398 |
8 |
0.024
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.024
|
Worm |
|
|
response to lipid
|
GO:0033993 |
206 |
0.024
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.024
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.024
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.024
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.024
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.023
|
|
|
|
response to fatty acid
|
GO:0070542 |
13 |
0.023
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.023
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.023
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.023
|
Yeast |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.023
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.023
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.023
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.023
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.023
|
|
|
|
acyl coa metabolic process
|
GO:0006637 |
23 |
0.023
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.023
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.023
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.023
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.023
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.022
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.022
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.022
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.022
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.022
|
Yeast Worm |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.022
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.022
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.022
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.022
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.022
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.022
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.022
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.022
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.021
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.021
|
|
|
|
thioester biosynthetic process
|
GO:0035384 |
6 |
0.021
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.021
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.021
|
Yeast |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.021
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.021
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.021
|
|
|
|
endosome organization
|
GO:0007032 |
20 |
0.021
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.021
|
Human |
|
|
thioester metabolic process
|
GO:0035383 |
23 |
0.021
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.021
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.021
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.021
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.021
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.020
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.020
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.020
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.020
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.020
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.020
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.020
|
Yeast |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.020
|
|
|
|
fibroblast apoptotic process
|
GO:0044346 |
8 |
0.020
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.020
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.020
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.020
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.020
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.020
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.020
|
|
|
|
regulation of tolerance induction
|
GO:0002643 |
4 |
0.020
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.020
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.020
|
Yeast |
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.020
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.020
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.020
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.019
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.019
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.019
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.019
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.019
|
Human |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.019
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.019
|
Worm |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.019
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.019
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.019
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.019
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.019
|
Yeast |
|
|
protein targeting
|
GO:0006605 |
187 |
0.019
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.019
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.019
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.019
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.018
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.018
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.018
|
Human |
|
|
immune effector process
|
GO:0002252 |
159 |
0.018
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.018
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.018
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.018
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.018
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.018
|
|
|
|
system process
|
GO:0003008 |
349 |
0.018
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.018
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.018
|
|
|
|
quinone metabolic process
|
GO:1901661 |
18 |
0.018
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.018
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.018
|
|
|
|
memory
|
GO:0007613 |
3 |
0.018
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.018
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.018
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.018
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.018
|
|
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.018
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.018
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.017
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.017
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.017
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.017
|
|
|
|
positive regulation of tolerance induction
|
GO:0002645 |
2 |
0.017
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.017
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.017
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.017
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.017
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.017
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.017
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.017
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.017
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.017
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.017
|
|
|
|
protein lipid complex subunit organization
|
GO:0071825 |
24 |
0.017
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.017
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.017
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.017
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.017
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.017
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.017
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.017
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.017
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.016
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.016
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.016
|
Yeast |
|
|
isoprenoid biosynthetic process
|
GO:0008299 |
9 |
0.016
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.016
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.016
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.016
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.016
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.016
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.016
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.016
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.016
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.016
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.016
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.016
|
|
|
|
protein lipid complex assembly
|
GO:0065005 |
12 |
0.016
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.016
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.016
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.016
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.016
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.016
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.016
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
6 |
0.016
|
|
|
|
growth
|
GO:0040007 |
202 |
0.016
|
Worm |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.016
|
Yeast |
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.016
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.016
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.016
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.015
|
Yeast |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.015
|
|
|
|
cellular response to hepatocyte growth factor stimulus
|
GO:0035729 |
6 |
0.015
|
|
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.015
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.015
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.015
|
|
|
|
acyl coa biosynthetic process
|
GO:0071616 |
6 |
0.015
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.015
|
|
|
|
negative regulation of heart growth
|
GO:0061117 |
2 |
0.015
|
|
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.015
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.015
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.015
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.015
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.015
|
|
