Homo sapiens

8 known processes

SLC3A2

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

(Aliases: MDU1,4T2HC,CD98,CD98HC,4F2HC,NACAE,4F2)

SLC3A2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cation transport GO:0015695 13 0.957
amino acid transport GO:0006865 28 0.893
organic anion transport GO:0015711 103 0.657
toxin transport GO:1901998 4 0.597
carboxylic acid transport GO:0046942 63 0.551
organic acid transport GO:0015849 65 0.479
anion transport GO:0006820 161 0.452
modified amino acid transport GO:0072337 11 0.427
regulation of cellular ketone metabolic process GO:0010565 50 0.348
cellular amino acid metabolic process GO:0006520 116 0.320
proline transport GO:0015824 4 0.287
chloride transmembrane transport GO:1902476 38 0.230
nitrogen compound transport GO:0071705 191 0.215
cellular macromolecule catabolic process GO:0044265 380 0.188
patterning of blood vessels GO:0001569 2 0.187
blood vessel maturation GO:0001955 1 0.180
post embryonic development GO:0009791 2 0.173
cation transport GO:0006812 331 0.155
cellular ketone metabolic process GO:0042180 80 0.152
transmembrane transport GO:0055085 399 0.146
cation transmembrane transport GO:0098655 238 0.137
intrinsic apoptotic signaling pathway GO:0097193 127 0.137
response to endoplasmic reticulum stress GO:0034976 49 0.122
amine metabolic process GO:0009308 44 0.116
modification dependent protein catabolic process GO:0019941 209 0.116
negative regulation of catalytic activity GO:0043086 335 0.108
regulation of cellular amino acid metabolic process GO:0006521 6 0.097
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.097
prostate gland morphogenesis GO:0060512 1 0.097
response to oxidative stress GO:0006979 121 0.096
regulation of cellular response to stress GO:0080135 244 0.087
alanine transport GO:0032328 3 0.087
negative regulation of cell death GO:0060548 345 0.085
cellular response to endogenous stimulus GO:0071495 336 0.085
amino acid transmembrane transport GO:0003333 20 0.084
negative regulation of phosphate metabolic process GO:0045936 267 0.084
cellular lipid metabolic process GO:0044255 303 0.082
positive regulation of cellular amine metabolic process GO:0033240 7 0.081
ubiquitin dependent protein catabolic process GO:0006511 206 0.079
l alanine transport GO:0015808 3 0.075
positive regulation of cell death GO:0010942 263 0.073
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.068
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.067
apoptotic signaling pathway GO:0097190 268 0.066
epithelium development GO:0060429 227 0.065
blood vessel development GO:0001568 172 0.065
response to toxic substance GO:0009636 37 0.064
cellular amine metabolic process GO:0044106 41 0.064
chemical homeostasis GO:0048878 306 0.060
regulation of cellular amine metabolic process GO:0033238 11 0.057
cytokine production GO:0001816 247 0.049
anatomical structure formation involved in morphogenesis GO:0048646 284 0.049
Zebrafish
positive regulation of neutrophil apoptotic process GO:0033031 1 0.048
epithelial cell differentiation GO:0030855 141 0.048
negative regulation of hydrolase activity GO:0051346 182 0.047
negative regulation of cellular component organization GO:0051129 235 0.046
trna aminoacylation for protein translation GO:0006418 8 0.046
negative regulation of phosphorus metabolic process GO:0010563 267 0.045
positive regulation of apoptotic process GO:0043065 246 0.043
circulatory system development GO:0072359 262 0.042
syncytium formation by plasma membrane fusion GO:0000768 2 0.041
Zebrafish
sulfur amino acid transport GO:0000101 2 0.041
cellular protein catabolic process GO:0044257 261 0.040
mapk cascade GO:0000165 288 0.039
regulation of homeostatic process GO:0032844 121 0.039
calcium ion transport GO:0006816 147 0.039
signal transduction by phosphorylation GO:0023014 297 0.039
carbohydrate metabolic process GO:0005975 207 0.038
regulation of response to dna damage stimulus GO:2001020 94 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
cell activation GO:0001775 213 0.037
ion homeostasis GO:0050801 230 0.037
neutrophil apoptotic process GO:0001781 2 0.037
small molecule biosynthetic process GO:0044283 157 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.036
regulation of proteolysis GO:0030162 293 0.036
fatty acid metabolic process GO:0006631 115 0.034
positive regulation of phosphorylation GO:0042327 394 0.034
regulation of transferase activity GO:0051338 355 0.034
negative regulation of homeostatic process GO:0032845 59 0.034
protein catabolic process GO:0030163 325 0.034
l amino acid import GO:0043092 4 0.034
cardiovascular system development GO:0072358 262 0.033
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.033
regulation of protein kinase activity GO:0045859 289 0.033
lipid metabolic process GO:0006629 381 0.033
organonitrogen compound biosynthetic process GO:1901566 200 0.032
negative regulation of protein processing GO:0010955 142 0.032
negative regulation of protein modification process GO:0031400 200 0.032
cellular chemical homeostasis GO:0055082 180 0.032
coenzyme metabolic process GO:0006732 65 0.032
positive regulation of programmed cell death GO:0043068 249 0.032
negative regulation of apoptotic process GO:0043066 316 0.032
protein modification by small protein conjugation GO:0032446 342 0.031
response to nutrient levels GO:0031667 81 0.030
cellular response to dna damage stimulus GO:0006974 379 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
metal ion transport GO:0030001 272 0.030
regulation of mapk cascade GO:0043408 262 0.029
regulation of cell migration GO:0030334 289 0.029
regulation of protein maturation GO:1903317 150 0.029
segmentation GO:0035282 4 0.029
biological adhesion GO:0022610 331 0.028
wound healing GO:0042060 115 0.028
response to organonitrogen compound GO:0010243 156 0.028
negative regulation of programmed cell death GO:0043069 321 0.028
tube development GO:0035295 125 0.028
negative regulation of phosphorylation GO:0042326 174 0.028
cytoplasmic transport GO:0016482 379 0.027
oxidation reduction process GO:0055114 396 0.027
system process GO:0003008 349 0.027
er nucleus signaling pathway GO:0006984 23 0.027
maintenance of location GO:0051235 112 0.027
response to abiotic stimulus GO:0009628 336 0.027
monocyte aggregation GO:0070487 4 0.027
branching morphogenesis of an epithelial tube GO:0048754 19 0.026
metencephalon development GO:0022037 2 0.026
mitochondrion organization GO:0007005 156 0.026
negative regulation of protein metabolic process GO:0051248 391 0.026
positive regulation of transport GO:0051050 336 0.026
response to extracellular stimulus GO:0009991 85 0.025
lipid modification GO:0030258 84 0.025
regulation of peptidyl serine phosphorylation GO:0033135 50 0.025
connective tissue development GO:0061448 39 0.025
cell division GO:0051301 168 0.025
secretion GO:0046903 254 0.025
proteasomal protein catabolic process GO:0010498 176 0.025
response to nitrogen compound GO:1901698 184 0.025
mucopolysaccharide metabolic process GO:1903510 27 0.025
cell adhesion GO:0007155 325 0.024
regulation of mitotic cell cycle GO:0007346 189 0.024
cellular response to oxidative stress GO:0034599 85 0.024
regulation of erk1 and erk2 cascade GO:0070372 99 0.024
regeneration GO:0031099 4 0.024
angiogenesis GO:0001525 147 0.024
positive regulation of protein phosphorylation GO:0001934 313 0.024
regulation of kinase activity GO:0043549 314 0.024
response to wounding GO:0009611 168 0.023
peptidyl serine modification GO:0018209 106 0.023
negative regulation of protein maturation GO:1903318 142 0.023
divalent inorganic cation transport GO:0072511 158 0.023
response to unfolded protein GO:0006986 24 0.023
regulation of leukocyte cell cell adhesion GO:1903037 7 0.023
single organism carbohydrate metabolic process GO:0044723 193 0.023
l serine metabolic process GO:0006563 5 0.023
regulation of dephosphorylation GO:0035303 96 0.023
tissue regeneration GO:0042246 3 0.023
d aspartate transport GO:0070777 3 0.023
basic amino acid transport GO:0015802 3 0.023
regulation of apoptotic signaling pathway GO:2001233 175 0.023
single organism cell adhesion GO:0098602 179 0.023
response to decreased oxygen levels GO:0036293 96 0.023
peptidyl serine phosphorylation GO:0018105 101 0.022
ion transmembrane transport GO:0034220 338 0.022
cellular response to biotic stimulus GO:0071216 71 0.022
sequestering of calcium ion GO:0051208 17 0.022
single organism membrane organization GO:0044802 268 0.022
cation homeostasis GO:0055080 189 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
regulation of cell growth GO:0001558 135 0.022
regulation of dna repair GO:0006282 47 0.022
mitotic cell cycle GO:0000278 326 0.021
cellular ion homeostasis GO:0006873 168 0.021
cell type specific apoptotic process GO:0097285 125 0.021
single organism cellular localization GO:1902580 332 0.021
regulation of locomotion GO:0040012 329 0.021
wnt signaling pathway GO:0016055 156 0.021
response to oxygen containing compound GO:1901700 369 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
vasculature development GO:0001944 181 0.020
sequestering of metal ion GO:0051238 24 0.020
response to topologically incorrect protein GO:0035966 29 0.020
cellular homeostasis GO:0019725 196 0.020
female gamete generation GO:0007292 2 0.020
protein processing GO:0016485 226 0.020
reactive oxygen species metabolic process GO:0072593 75 0.020
amino acid import GO:0043090 4 0.020
regulation of lipid biosynthetic process GO:0046890 47 0.020
wound healing involved in inflammatory response GO:0002246 2 0.020
d aspartate import GO:0070779 3 0.020
renal tubule development GO:0061326 19 0.020
cellular metal ion homeostasis GO:0006875 146 0.020
modification dependent macromolecule catabolic process GO:0043632 212 0.019
urogenital system development GO:0001655 65 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
nucleoside catabolic process GO:0009164 408 0.019
vesicle mediated transport GO:0016192 371 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
metal ion homeostasis GO:0055065 169 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.019
anatomical structure maturation GO:0071695 9 0.018
negative regulation of immune system process GO:0002683 136 0.018
nephron tubule morphogenesis GO:0072078 13 0.018
ribonucleoside monophosphate catabolic process GO:0009158 158 0.018
one carbon metabolic process GO:0006730 1 0.018
positive regulation of transferase activity GO:0051347 227 0.018
lymphocyte homeostasis GO:0002260 4 0.018
cellular calcium ion homeostasis GO:0006874 117 0.018
carbohydrate transport GO:0008643 37 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
cell development GO:0048468 328 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.018
atp catabolic process GO:0006200 157 0.018
negative regulation of peptidase activity GO:0010466 91 0.018
myeloid cell differentiation GO:0030099 117 0.017
dephosphorylation GO:0016311 209 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
secretion by cell GO:0032940 226 0.017
epithelial tube morphogenesis GO:0060562 38 0.017
atp metabolic process GO:0046034 176 0.017
signal transduction by p53 class mediator GO:0072331 72 0.017
myeloid cell homeostasis GO:0002262 34 0.017
response to nutrient GO:0007584 20 0.017
negative regulation of cell migration GO:0030336 102 0.017
regulation of dna metabolic process GO:0051052 153 0.017
regulation of lipid metabolic process GO:0019216 96 0.017
negative regulation of protein kinase activity GO:0006469 98 0.017
protein maturation GO:0051604 233 0.016
determination of adult lifespan GO:0008340 2 0.016
regulation of cell activation GO:0050865 125 0.016
cellular response to unfolded protein GO:0034620 16 0.016
positive regulation of immune system process GO:0002684 283 0.016
positive regulation of cellular catabolic process GO:0031331 284 0.016
positive regulation of cellular component organization GO:0051130 376 0.016
multicellular organismal aging GO:0010259 3 0.016
regulation of vesicle mediated transport GO:0060627 130 0.016
membrane organization GO:0061024 292 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.016
regulation of ion transmembrane transport GO:0034765 132 0.016
oogenesis GO:0048477 2 0.016
head development GO:0060322 108 0.016
regulation of growth GO:0040008 165 0.016
rna splicing GO:0008380 131 0.016
negative regulation of locomotion GO:0040013 118 0.016
oocyte differentiation GO:0009994 2 0.016
cellular divalent inorganic cation homeostasis GO:0072503 128 0.016
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
nephron tubule development GO:0072080 17 0.015
regulation of cellular component movement GO:0051270 334 0.015
regulation of cell cycle process GO:0010564 266 0.015
inorganic ion transmembrane transport GO:0098660 231 0.015
cellular response to lipid GO:0071396 127 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
negative regulation of cell differentiation GO:0045596 171 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.015
reproductive system development GO:0061458 56 0.015
regulation of ion transport GO:0043269 189 0.015
l amino acid transport GO:0015807 14 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
cell growth GO:0016049 160 0.014
regulation of protein serine threonine kinase activity GO:0071900 179 0.014
erk1 and erk2 cascade GO:0070371 104 0.014
negative regulation of phosphatase activity GO:0010923 61 0.014
positive regulation of organelle organization GO:0010638 195 0.014
divalent metal ion transport GO:0070838 152 0.014
response to starvation GO:0042594 59 0.014
protein ubiquitination GO:0016567 314 0.014
growth GO:0040007 202 0.014
renal system development GO:0072001 63 0.014
locomotory behavior GO:0007626 1 0.014
response to peptide GO:1901652 65 0.014
establishment of protein localization to membrane GO:0090150 121 0.014
regulation of ion homeostasis GO:2000021 73 0.014
hexose metabolic process GO:0019318 55 0.014
oocyte development GO:0048599 1 0.014
alpha amino acid metabolic process GO:1901605 72 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
protein localization to membrane GO:0072657 160 0.014
nephron morphogenesis GO:0072028 15 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.013
translation GO:0006412 132 0.013
regulation of cell development GO:0060284 161 0.013
motor neuron axon guidance GO:0008045 2 0.013
regulation of phosphatase activity GO:0010921 81 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
regulation of intracellular transport GO:0032386 195 0.013
negative regulation of transferase activity GO:0051348 124 0.013
regulation of angiogenesis GO:0045765 92 0.013
immune system development GO:0002520 195 0.013
regulation of calcium ion transport GO:0051924 79 0.013
ribonucleoside triphosphate metabolic process GO:0009199 412 0.013
regulation of secretion GO:0051046 194 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of cell division GO:0051302 116 0.013
kidney morphogenesis GO:0060993 19 0.013
blastoderm segmentation GO:0007350 2 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
negative regulation of organelle organization GO:0010639 126 0.013
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.013
negative regulation of developmental process GO:0051093 247 0.013
response to oxygen levels GO:0070482 100 0.013
glycerolipid metabolic process GO:0046486 107 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
morphogenesis of a branching structure GO:0001763 21 0.012
cell projection organization GO:0030030 252 0.012
mitotic cell cycle process GO:1903047 286 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.012
hemopoiesis GO:0030097 180 0.012
macrophage fusion GO:0034238 1 0.012
hindbrain development GO:0030902 3 0.012
regulation of axon guidance GO:1902667 3 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
organophosphate catabolic process GO:0046434 430 0.012
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
regulation of cytokine production GO:0001817 232 0.012
embryo development GO:0009790 123 0.012
protein oligomerization GO:0051259 173 0.012
rna processing GO:0006396 255 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
ncrna metabolic process GO:0034660 108 0.012
immune response GO:0006955 307 0.012
inorganic anion transmembrane transport GO:0098661 47 0.012
cellular lipid catabolic process GO:0044242 65 0.012
neurogenesis GO:0022008 169 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
leukocyte apoptotic process GO:0071887 31 0.012
positive regulation of apoptotic signaling pathway GO:2001235 70 0.012
fatty acid biosynthetic process GO:0006633 46 0.012
response to external biotic stimulus GO:0043207 261 0.012
lipid oxidation GO:0034440 33 0.012
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.012
regulation of metal ion transport GO:0010959 120 0.012
response to fungus GO:0009620 4 0.012
nephron epithelium morphogenesis GO:0072088 15 0.012
regulation of protein localization GO:0032880 296 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
regulation of cell cycle GO:0051726 393 0.012
positive regulation of kinase activity GO:0033674 204 0.012
chloride transport GO:0006821 41 0.012
regulation of neutrophil apoptotic process GO:0033029 1 0.012
regulation of mitosis GO:0007088 63 0.012
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of cellular component biogenesis GO:0044087 281 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.011
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
cellular response to decreased oxygen levels GO:0036294 51 0.011
cellular response to topologically incorrect protein GO:0035967 19 0.011
response to lipid GO:0033993 206 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
spermatid differentiation GO:0048515 4 0.011
b cell homeostasis GO:0001782 1 0.011
brain development GO:0007420 97 0.011
positive regulation of catabolic process GO:0009896 310 0.011
regulation of mitotic cell cycle phase transition GO:1901990 118 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
signal transduction in response to dna damage GO:0042770 57 0.011
regulation of multi organism process GO:0043900 157 0.011
regulation of peptidase activity GO:0052547 180 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
neurological system process GO:0050877 163 0.011
lipid biosynthetic process GO:0008610 177 0.011
monocarboxylic acid transport GO:0015718 32 0.011
response to inorganic substance GO:0010035 127 0.011
dna templated transcription termination GO:0006353 3 0.011
regulation of protein processing GO:0070613 150 0.011
cellular cation homeostasis GO:0030003 163 0.011
aspartate transport GO:0015810 5 0.011
regulation of map kinase activity GO:0043405 108 0.011
trna metabolic process GO:0006399 35 0.011
negative regulation of response to dna damage stimulus GO:2001021 33 0.011
mitotic nuclear division GO:0007067 119 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
purine ribonucleoside metabolic process GO:0046128 437 0.011
ureteric bud morphogenesis GO:0060675 10 0.011
serine family amino acid metabolic process GO:0009069 12 0.011
endocytosis GO:0006897 159 0.010
innate immune response GO:0045087 178 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.010
negative regulation of cell cycle process GO:0010948 121 0.010
muscle cell cellular homeostasis GO:0046716 3 0.010
cardiac muscle contraction GO:0060048 34 0.010
lens development in camera type eye GO:0002088 2 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.010
t cell differentiation in thymus GO:0033077 4 0.010
inflammatory response to wounding GO:0090594 2 0.010
divalent inorganic cation homeostasis GO:0072507 136 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.010
muscle contraction GO:0006936 73 0.010
anterior posterior axis specification embryo GO:0008595 2 0.010
defense response GO:0006952 315 0.010
ribonucleoside triphosphate catabolic process GO:0009203 391 0.010
carboxylic acid catabolic process GO:0046395 71 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
ribonucleotide catabolic process GO:0009261 405 0.010
spermatid development GO:0007286 4 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
positive regulation of immune response GO:0050778 159 0.010

SLC3A2 disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.101
neuropathy DOID:870 52 0.101
central nervous system disease DOID:331 186 0.037
disease of metabolism DOID:0014667 295 0.022
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
organ system cancer DOID:0050686 164 0.015
inherited metabolic disorder DOID:655 242 0.014
musculoskeletal system disease DOID:17 223 0.013
neurodegenerative disease DOID:1289 102 0.013
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
eye disease DOID:5614 149 0.013
neuromuscular disease DOID:440 38 0.012
motor neuron disease DOID:231 27 0.011
distal hereditary motor neuropathy DOID:0050582 5 0.011
motor neuritis DOID:683 5 0.011