Homo sapiens

100 known processes

MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2

(Aliases: GCK,RAB8IP,BL44)

MAP4K2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 80 0.161
purine containing compound catabolic process GO:0072523 411 0.160
ribonucleoside triphosphate metabolic process GO:0009199 412 0.158
activation of jnkk activity GO:0007256 1 0.142
cellular amino acid metabolic process GO:0006520 116 0.134
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.128
nucleoside phosphate catabolic process GO:1901292 412 0.126
purine nucleoside triphosphate catabolic process GO:0009146 392 0.119
response to oxygen containing compound GO:1901700 369 0.119
Fly
positive regulation of mapk cascade GO:0043410 190 0.110
regulation of transferase activity GO:0051338 355 0.110
gtp metabolic process GO:0046039 239 0.109
purine nucleotide catabolic process GO:0006195 405 0.107
purine nucleoside triphosphate metabolic process GO:0009144 412 0.107
cellular amine metabolic process GO:0044106 41 0.103
regulation of protein kinase activity GO:0045859 289 0.101
positive regulation of nucleotide catabolic process GO:0030813 185 0.097
purine ribonucleoside metabolic process GO:0046128 437 0.097
nucleoside triphosphate metabolic process GO:0009141 422 0.095
ras protein signal transduction GO:0007265 73 0.093
nucleoside catabolic process GO:0009164 408 0.092
ribonucleoside triphosphate catabolic process GO:0009203 391 0.092
mapk cascade GO:0000165 288 0.091
organophosphate catabolic process GO:0046434 430 0.091
nucleotide catabolic process GO:0009166 408 0.089
purine nucleoside catabolic process GO:0006152 398 0.088
response to abiotic stimulus GO:0009628 336 0.087
Human
regulation of cellular amine metabolic process GO:0033238 11 0.086
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.086
regulation of cellular amino acid metabolic process GO:0006521 6 0.085
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.083
ribonucleotide catabolic process GO:0009261 405 0.082
purine ribonucleotide catabolic process GO:0009154 404 0.080
purine ribonucleoside catabolic process GO:0046130 398 0.080
positive regulation of cellular amine metabolic process GO:0033240 7 0.078
positive regulation of protein phosphorylation GO:0001934 313 0.075
amine metabolic process GO:0009308 44 0.075
regulation of nucleotide metabolic process GO:0006140 269 0.075
regulation of nucleotide catabolic process GO:0030811 205 0.073
positive regulation of cellular catabolic process GO:0031331 284 0.071
signal transduction by phosphorylation GO:0023014 297 0.070
regulation of map kinase activity GO:0043405 108 0.070
positive regulation of programmed cell death GO:0043068 249 0.068
Fly
determination of adult lifespan GO:0008340 2 0.063
post embryonic development GO:0009791 2 0.061
multicellular organismal aging GO:0010259 3 0.060
rho protein signal transduction GO:0007266 26 0.060
regulation of protein localization GO:0032880 296 0.059
regulation of cell migration GO:0030334 289 0.059
regulation of kinase activity GO:0043549 314 0.058
regulation of purine nucleotide catabolic process GO:0033121 205 0.058
regulation of gtpase activity GO:0043087 180 0.058
positive regulation of phosphorylation GO:0042327 394 0.057
negative regulation of cellular protein metabolic process GO:0032269 353 0.056
stress activated protein kinase signaling cascade GO:0031098 94 0.056
positive regulation of cell death GO:0010942 263 0.056
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.055
cellular response to endogenous stimulus GO:0071495 336 0.055
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.055
Fly
regulation of small gtpase mediated signal transduction GO:0051056 156 0.055
regulation of cellular component movement GO:0051270 334 0.053
regulation of protein serine threonine kinase activity GO:0071900 179 0.052
positive regulation of gtpase activity GO:0043547 166 0.051
positive regulation of nucleotide metabolic process GO:0045981 230 0.051
positive regulation of transferase activity GO:0051347 227 0.051
nucleoside triphosphate catabolic process GO:0009143 394 0.050
ribonucleoside catabolic process GO:0042454 406 0.050
glycosyl compound catabolic process GO:1901658 413 0.049
guanosine containing compound catabolic process GO:1901069 239 0.049
memory GO:0007613 3 0.047
peptidyl serine phosphorylation GO:0018105 101 0.046
Human
response to hormone GO:0009725 175 0.045
Fly
negative regulation of catalytic activity GO:0043086 335 0.045
cellular macromolecular complex assembly GO:0034622 324 0.045
cellular response to oxygen containing compound GO:1901701 276 0.043
Fly
regulation of ras protein signal transduction GO:0046578 155 0.043
regulation of cell differentiation GO:0045595 393 0.043
cdc42 protein signal transduction GO:0032488 4 0.043
regulation of gtp catabolic process GO:0033124 180 0.042
positive regulation of gtp catabolic process GO:0033126 166 0.042
negative regulation of cellular component organization GO:0051129 235 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
female gamete generation GO:0007292 2 0.042
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.042
regulation of cellular ketone metabolic process GO:0010565 50 0.041
immune response GO:0006955 307 0.041
guanosine containing compound metabolic process GO:1901068 244 0.041
regulation of establishment of protein localization GO:0070201 242 0.040
regulation of cellular component biogenesis GO:0044087 281 0.040
cytoplasmic transport GO:0016482 379 0.038
single organism cellular localization GO:1902580 332 0.038
negative regulation of phosphate metabolic process GO:0045936 267 0.038
regulation of cell cycle GO:0051726 393 0.037
cell type specific apoptotic process GO:0097285 125 0.037
positive regulation of stress activated mapk cascade GO:0032874 60 0.037
jnk cascade GO:0007254 80 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.037
Fly
cellular lipid metabolic process GO:0044255 303 0.036
associative learning GO:0008306 1 0.036
positive regulation of kinase activity GO:0033674 204 0.036
regulation of mapk cascade GO:0043408 262 0.035
apoptotic signaling pathway GO:0097190 268 0.035
microtubule based process GO:0007017 210 0.034
locomotory behavior GO:0007626 1 0.034
peptidyl threonine phosphorylation GO:0018107 41 0.034
transmembrane transport GO:0055085 399 0.033
regulation of cell motility GO:2000145 299 0.032
response to organonitrogen compound GO:0010243 156 0.032
Fly
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.032
regulation of secretion by cell GO:1903530 177 0.032
actin cytoskeleton organization GO:0030036 207 0.032
g protein coupled receptor signaling pathway GO:0007186 207 0.031
positive regulation of apoptotic process GO:0043065 246 0.031
Fly
peptidyl threonine modification GO:0018210 45 0.031
positive regulation of cell cycle GO:0045787 140 0.031
epithelial cell differentiation GO:0030855 141 0.031
response to nitrogen compound GO:1901698 184 0.030
Fly
positive regulation of transport GO:0051050 336 0.030
peptidyl serine modification GO:0018209 106 0.030
Human
secretion GO:0046903 254 0.030
negative regulation of protein metabolic process GO:0051248 391 0.030
regulation of rho protein signal transduction GO:0035023 79 0.029
regulation of purine nucleotide metabolic process GO:1900542 264 0.028
lipid metabolic process GO:0006629 381 0.028
neuromuscular junction development GO:0007528 3 0.028
covalent chromatin modification GO:0016569 254 0.028
gtp catabolic process GO:0006184 237 0.028
stress activated mapk cascade GO:0051403 93 0.028
vesicle mediated transport GO:0016192 371 0.028
Mouse
epithelium development GO:0060429 227 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
thyroid hormone transport GO:0070327 2 0.028
oogenesis GO:0048477 2 0.027
response to external biotic stimulus GO:0043207 261 0.027
regulation of proteolysis GO:0030162 293 0.027
regulation of stress activated mapk cascade GO:0032872 84 0.027
cellular component morphogenesis GO:0032989 314 0.027
regulation of jnk cascade GO:0046328 73 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
nervous system development GO:0007399 293 0.027
organ formation GO:0048645 3 0.027
mitochondrion organization GO:0007005 156 0.026
negative regulation of hydrolase activity GO:0051346 182 0.026
negative regulation of protein maturation GO:1903318 142 0.026
oxidation reduction process GO:0055114 396 0.026
intracellular protein transport GO:0006886 270 0.026
regulation of cellular response to stress GO:0080135 244 0.026
cell projection organization GO:0030030 252 0.026
atp metabolic process GO:0046034 176 0.026
regulation of protein maturation GO:1903317 150 0.026
positive regulation of cellular component biogenesis GO:0044089 158 0.025
cellular protein complex assembly GO:0043623 188 0.025
response to peptide hormone GO:0043434 61 0.025
Fly
regulation of locomotion GO:0040012 329 0.025
defense response GO:0006952 315 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
positive regulation of nucleoside metabolic process GO:0045979 186 0.025
chromatin organization GO:0006325 351 0.025
positive regulation of developmental process GO:0051094 314 0.025
positive regulation of cellular component organization GO:0051130 376 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.024
protein modification by small protein conjugation GO:0032446 342 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.024
positive regulation of catabolic process GO:0009896 310 0.024
regulation of secretion GO:0051046 194 0.024
regulation of synaptic plasticity GO:0048167 3 0.024
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.024
secretion by cell GO:0032940 226 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
organic anion transport GO:0015711 103 0.024
segmentation GO:0035282 4 0.024
negative regulation of proteolysis GO:0045861 132 0.024
cellular response to insulin stimulus GO:0032869 41 0.023
Fly
mitotic cell cycle GO:0000278 326 0.023
cellular response to dna damage stimulus GO:0006974 379 0.023
reactive oxygen species metabolic process GO:0072593 75 0.023
response to peptide GO:1901652 65 0.023
Fly
regulation of protein complex assembly GO:0043254 147 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
interspecies interaction between organisms GO:0044419 156 0.023
nuclear transport GO:0051169 179 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
histone modification GO:0016570 251 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.023
atp catabolic process GO:0006200 157 0.023
cation transport GO:0006812 331 0.023
response to other organism GO:0051707 261 0.023
protein localization to membrane GO:0072657 160 0.023
protein processing GO:0016485 226 0.023
growth GO:0040007 202 0.023
Fly
positive regulation of cellular component movement GO:0051272 181 0.022
regulation of growth rate GO:0040009 1 0.022
Fly
viral process GO:0016032 146 0.022
protein maturation GO:0051604 233 0.022
peptidyl lysine modification GO:0018205 144 0.022
regulation of protein processing GO:0070613 150 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
cell development GO:0048468 328 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
activation of protein kinase activity GO:0032147 90 0.022
regulation of intracellular transport GO:0032386 195 0.022
chromatin modification GO:0016568 298 0.022
positive regulation of cell motility GO:2000147 177 0.022
regulation of jun kinase activity GO:0043506 27 0.022
response to alcohol GO:0097305 64 0.021
Fly
nucleocytoplasmic transport GO:0006913 176 0.021
response to insulin GO:0032868 45 0.021
Fly
positive regulation of cell differentiation GO:0045597 211 0.021
negative regulation of protein phosphorylation GO:0001933 140 0.021
actin filament based process GO:0030029 224 0.021
exocytosis GO:0006887 71 0.021
ion homeostasis GO:0050801 230 0.021
neurological system process GO:0050877 163 0.021
cell growth GO:0016049 160 0.020
regulation of microtubule based process GO:0032886 74 0.020
negative regulation of organelle organization GO:0010639 126 0.020
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.020
negative regulation of protein processing GO:0010955 142 0.020
peptidyl tyrosine phosphorylation GO:0018108 170 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
regulation of cysteine type endopeptidase activity GO:2000116 127 0.020
regulation of endopeptidase activity GO:0052548 170 0.020
positive regulation of synaptic transmission GO:0050806 4 0.020
cell projection assembly GO:0030031 126 0.020
protein catabolic process GO:0030163 325 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.020
positive regulation of locomotion GO:0040017 186 0.020
nitrogen compound transport GO:0071705 191 0.020
negative regulation of protein modification process GO:0031400 200 0.019
establishment of protein localization to membrane GO:0090150 121 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
neuron death GO:0070997 65 0.019
cell fate determination GO:0001709 3 0.019
regulation of ras gtpase activity GO:0032318 128 0.019
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
response to light stimulus GO:0009416 87 0.019
Human
maintenance of location GO:0051235 112 0.019
negative regulation of endopeptidase activity GO:0010951 84 0.019
mitotic cell cycle process GO:1903047 286 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
adult locomotory behavior GO:0008344 1 0.018
viral life cycle GO:0019058 132 0.018
innate immune response GO:0045087 178 0.018
regulation of binding GO:0051098 111 0.018
metal ion transport GO:0030001 272 0.018
regulation of microtubule cytoskeleton organization GO:0070507 61 0.018
multi organism cellular process GO:0044764 156 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
positive regulation of secretion by cell GO:1903532 108 0.018
regulation of cell development GO:0060284 161 0.018
positive regulation of rho gtpase activity GO:0032321 56 0.018
single organism membrane organization GO:0044802 268 0.018
purine nucleoside monophosphate catabolic process GO:0009128 158 0.018
negative regulation of gliogenesis GO:0014014 3 0.018
generation of neurons GO:0048699 152 0.017
regulation of cell projection organization GO:0031344 107 0.017
ion transmembrane transport GO:0034220 338 0.017
histone serine phosphorylation GO:0035404 4 0.017
regulation of dna metabolic process GO:0051052 153 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
protein localization to organelle GO:0033365 280 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
positive regulation of jun kinase activity GO:0043507 23 0.017
cellular response to abiotic stimulus GO:0071214 117 0.017
regulation of chromosome organization GO:0033044 103 0.017
receptor metabolic process GO:0043112 81 0.017
cellular response to nitrogen compound GO:1901699 144 0.017
Fly
protein acylation GO:0043543 138 0.017
regulation of rho gtpase activity GO:0032319 66 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
regeneration GO:0031099 4 0.016
anion transport GO:0006820 161 0.016
oocyte development GO:0048599 1 0.016
system process GO:0003008 349 0.016
regulation of cell cycle process GO:0010564 266 0.016
oocyte differentiation GO:0009994 2 0.016
regulation of anatomical structure size GO:0090066 101 0.016
Fly
regulation of growth GO:0040008 165 0.016
Fly
response to extracellular stimulus GO:0009991 85 0.016
negative regulation of cell death GO:0060548 345 0.016
positive regulation of cell proliferation GO:0008284 301 0.016
mitotic nuclear division GO:0007067 119 0.016
photoreceptor cell differentiation GO:0046530 2 0.016
response to hypoxia GO:0001666 96 0.016
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
regulation of protein transport GO:0051223 213 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
leukocyte activation GO:0045321 164 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
regulation of cell adhesion GO:0030155 166 0.015
long term memory GO:0007616 2 0.015
immune system development GO:0002520 195 0.015
regulation of exocytosis GO:0017157 46 0.015
protein homooligomerization GO:0051260 100 0.015
response to decreased oxygen levels GO:0036293 96 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
response to radiation GO:0009314 151 0.015
Human
cation transmembrane transport GO:0098655 238 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
muscle system process GO:0003012 81 0.015
actin filament bundle assembly GO:0051017 54 0.015
regulation of membrane potential GO:0042391 95 0.015
ubiquitin dependent protein catabolic process GO:0006511 206 0.015
regulation of reactive oxygen species metabolic process GO:2000377 41 0.015
activation of mapkk activity GO:0000186 18 0.015
response to bacterium GO:0009617 144 0.014
somatic stem cell division GO:0048103 1 0.014
endodermal cell fate commitment GO:0001711 4 0.014
internal protein amino acid acetylation GO:0006475 101 0.014
sequestering of calcium ion GO:0051208 17 0.014
negative regulation of cell cycle GO:0045786 193 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.014
blastoderm segmentation GO:0007350 2 0.014
regulation of response to external stimulus GO:0032101 222 0.014
cation homeostasis GO:0055080 189 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
somatic stem cell maintenance GO:0035019 4 0.014
activation of immune response GO:0002253 114 0.014
organic hydroxy compound metabolic process GO:1901615 147 0.014
cell cycle phase transition GO:0044770 173 0.014
cellular ion homeostasis GO:0006873 168 0.014
negative regulation of cytoskeleton organization GO:0051494 45 0.014
lipid biosynthetic process GO:0008610 177 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
response to wounding GO:0009611 168 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
defense response to other organism GO:0098542 129 0.014
sensory perception of smell GO:0007608 2 0.014
nucleoside monophosphate metabolic process GO:0009123 191 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
dephosphorylation GO:0016311 209 0.014
ameboidal type cell migration GO:0001667 135 0.014
mitotic cell cycle phase transition GO:0044772 162 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
cardiac muscle contraction GO:0060048 34 0.014
positive regulation of immune system process GO:0002684 283 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
cell activation GO:0001775 213 0.014
protein oligomerization GO:0051259 173 0.014
cellular protein catabolic process GO:0044257 261 0.014
heart formation GO:0060914 2 0.014
cell matrix adhesion GO:0007160 85 0.014
plasma membrane organization GO:0007009 115 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.014
organophosphate biosynthetic process GO:0090407 163 0.013
negative regulation of transport GO:0051051 176 0.013
biological adhesion GO:0022610 331 0.013
glycoprotein metabolic process GO:0009100 110 0.013
metal ion homeostasis GO:0055065 169 0.013
protein localization to plasma membrane GO:0072659 93 0.013
negative regulation of kinase activity GO:0033673 106 0.013
endosomal transport GO:0016197 129 0.013
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.013
circadian behavior GO:0048512 2 0.013
tissue regeneration GO:0042246 3 0.013
regulation of cytokine production GO:0001817 232 0.013
visual learning GO:0008542 1 0.013
rna processing GO:0006396 255 0.013
regulation of epithelial cell migration GO:0010632 93 0.013
rhythmic behavior GO:0007622 2 0.013
cellular response to peptide GO:1901653 59 0.013
Fly
negative regulation of peptidase activity GO:0010466 91 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.013
regulation of cell growth GO:0001558 135 0.013
epithelium migration GO:0090132 119 0.013
nucleoside phosphate biosynthetic process GO:1901293 109 0.013
neuron apoptotic process GO:0051402 39 0.013
actin filament bundle organization GO:0061572 54 0.013
limbic system development GO:0021761 3 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
vesicle organization GO:0016050 62 0.013
cardiovascular system development GO:0072358 262 0.013
protein ubiquitination GO:0016567 314 0.013
carbohydrate metabolic process GO:0005975 207 0.013
negative regulation of transferase activity GO:0051348 124 0.013
cellular response to extracellular stimulus GO:0031668 72 0.013
neuroblast proliferation GO:0007405 4 0.013
cellular response to external stimulus GO:0071496 111 0.013
protein acetylation GO:0006473 116 0.013
cell morphogenesis involved in differentiation GO:0000904 144 0.013
peripheral nervous system development GO:0007422 2 0.013
endodermal cell fate specification GO:0001714 4 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
regulation of neuron apoptotic process GO:0043523 35 0.012
positive regulation of secretion GO:0051047 116 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
behavior GO:0007610 112 0.012
Fly
chemotaxis GO:0006935 157 0.012
response to oxidative stress GO:0006979 121 0.012
nuclear division GO:0000280 128 0.012
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.012
metencephalon development GO:0022037 2 0.012
regulation of multi organism process GO:0043900 157 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of cell substrate adhesion GO:0010810 68 0.012
regulation of cellular component size GO:0032535 82 0.012
Fly
positive regulation of ras gtpase activity GO:0032320 117 0.012
visual behavior GO:0007632 2 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
negative regulation of immune system process GO:0002683 136 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
positive regulation of purine nucleotide biosynthetic process GO:1900373 38 0.012
positive regulation of protein transport GO:0051222 135 0.012
negative regulation of cell differentiation GO:0045596 171 0.012
regulation of protein binding GO:0043393 66 0.012
hindbrain development GO:0030902 3 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
regulation of erk1 and erk2 cascade GO:0070372 99 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
regulation of immune response GO:0050776 201 0.012
neuron development GO:0048666 113 0.012
negative regulation of protein kinase activity GO:0006469 98 0.011
organelle assembly GO:0070925 176 0.011
negative regulation of cell migration GO:0030336 102 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
wnt signaling pathway GO:0016055 156 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of peptidase activity GO:0052547 180 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
regulation of ion transport GO:0043269 189 0.011
tripartite regional subdivision GO:0007351 2 0.011
syncytium formation by plasma membrane fusion GO:0000768 2 0.011
regulation of neural precursor cell proliferation GO:2000177 4 0.011
prostate gland development GO:0030850 3 0.011
response to lipid GO:0033993 206 0.011
cell morphogenesis GO:0000902 296 0.011
neurogenesis GO:0022008 169 0.011
spermatid differentiation GO:0048515 4 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.011
positive regulation of map kinase activity GO:0043406 80 0.011
negative regulation of monocyte differentiation GO:0045656 3 0.011
mating GO:0007618 1 0.011
regulation of viral process GO:0050792 103 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
immune response activating signal transduction GO:0002757 90 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.011
internal peptidyl lysine acetylation GO:0018393 97 0.011
cellular homeostasis GO:0019725 196 0.011
response to oxygen levels GO:0070482 100 0.011
tissue migration GO:0090130 119 0.011
aortic valve development GO:0003176 3 0.011
regulation of homeostatic process GO:0032844 121 0.011
positive regulation of proteolysis GO:0045862 142 0.011
positive regulation of cell development GO:0010720 92 0.011
erk1 and erk2 cascade GO:0070371 104 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.011
peptidyl lysine acetylation GO:0018394 101 0.011
regulation of chromatin organization GO:1902275 56 0.011
regulation of cardioblast differentiation GO:0051890 4 0.011
regulation of cell activation GO:0050865 125 0.011
regulation of chromatin modification GO:1903308 51 0.011
regulation of transporter activity GO:0032409 82 0.011
asymmetric neuroblast division GO:0055059 1 0.011
positive regulation of binding GO:0051099 45 0.011
response to temperature stimulus GO:0009266 22 0.011
head development GO:0060322 108 0.011
methylation GO:0032259 106 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
protein targeting GO:0006605 187 0.011
immune effector process GO:0002252 159 0.011
cytokinesis GO:0000910 96 0.011
protein autophosphorylation GO:0046777 123 0.011
Human
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
circulatory system development GO:0072359 262 0.011
neuroblast division GO:0055057 1 0.011
salivary gland morphogenesis GO:0007435 4 0.011
detection of stimulus GO:0051606 85 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
cellular chemical homeostasis GO:0055082 180 0.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.011
spermatid development GO:0007286 4 0.011

MAP4K2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.032
nervous system disease DOID:863 431 0.032
disease of metabolism DOID:0014667 295 0.023
disease of cellular proliferation DOID:14566 174 0.023
cancer DOID:162 167 0.022
organ system cancer DOID:0050686 164 0.022
inherited metabolic disorder DOID:655 242 0.015
neurodegenerative disease DOID:1289 102 0.012
musculoskeletal system disease DOID:17 223 0.012
connective tissue disease DOID:65 109 0.012
sensory system disease DOID:0050155 203 0.012